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The map label for this gene is hmp [H]

Identifier: 110833719

GI number: 110833719

Start: 956514

End: 956921

Strand: Direct

Name: hmp [H]

Synonym: ABO_0858

Alternate gene names: 110833719

Gene position: 956514-956921 (Clockwise)

Preceding gene: 110833718

Following gene: 110833720

Centisome position: 30.66

GC content: 55.39

Gene sequence:

>408_bases
ATGACTCCGGTACAGATTGCTTTGGTACAGAACAGCTGGGACAAGGTGGATGCTATTTCCGATCAGGCTGCGAGCTTGTT
TTACGATCGCCTGTTTACCAATGACCCCGCCCTGAAACCGCTCTTCAAGGGCAACATGGAAGAACAGGGCAAGAAGCTGA
TGACCATGATTGGTGTGGCAGTGAGAGGCTTGGACAAGCTCGATACCATCGTCCCCGCTGTTCAGAAGCTGGGCGCTCGT
CACAAGGATTATGGTGTGAAACCAGCAGACTACGACACGGTGGCACAGGCCTTGCTTTGGACTTTGGGCCAGGGGCTGGG
CGATGCGTTCGACAGCGACACAGAAGCCGCCTGGGTTGCCGCCTACACCATTTTGGCCACGACCATGATTGCCGCCGCGG
ACTATTAA

Upstream 100 bases:

>100_bases
TAAAGTTCGATCAACAACGACCCAAGTACGGGCTTAACCGATTATAGCGTCGGATGGGCGGCGCTAAAGGCCATTATCTA
TATTCAACGGGAGAAACATC

Downstream 100 bases:

>100_bases
GGCGCCTAGAGGGATAAGGGCCATTTTGGCACCTGGATTTGCACCACAATGGCTCGCTTTTGGGGTGCCTTATTCATGGA
AAATAAAATAGACCATAAAA

Product: oxidoreductase

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MTPVQIALVQNSWDKVDAISDQAASLFYDRLFTNDPALKPLFKGNMEEQGKKLMTMIGVAVRGLDKLDTIVPAVQKLGAR
HKDYGVKPADYDTVAQALLWTLGQGLGDAFDSDTEAAWVAAYTILATTMIAAADY

Sequences:

>Translated_135_residues
MTPVQIALVQNSWDKVDAISDQAASLFYDRLFTNDPALKPLFKGNMEEQGKKLMTMIGVAVRGLDKLDTIVPAVQKLGAR
HKDYGVKPADYDTVAQALLWTLGQGLGDAFDSDTEAAWVAAYTILATTMIAAADY
>Mature_134_residues
TPVQIALVQNSWDKVDAISDQAASLFYDRLFTNDPALKPLFKGNMEEQGKKLMTMIGVAVRGLDKLDTIVPAVQKLGARH
KDYGVKPADYDTVAQALLWTLGQGLGDAFDSDTEAAWVAAYTILATTMIAAADY

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI10864065, Length=137, Percent_Identity=29.1970802919708, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788903, Length=109, Percent_Identity=33.0275229357798, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 14669; Mature: 14538

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVQIALVQNSWDKVDAISDQAASLFYDRLFTNDPALKPLFKGNMEEQGKKLMTMIGVA
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHH
VRGLDKLDTIVPAVQKLGARHKDYGVKPADYDTVAQALLWTLGQGLGDAFDSDTEAAWVA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AYTILATTMIAAADY
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPVQIALVQNSWDKVDAISDQAASLFYDRLFTNDPALKPLFKGNMEEQGKKLMTMIGVA
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHH
VRGLDKLDTIVPAVQKLGARHKDYGVKPADYDTVAQALLWTLGQGLGDAFDSDTEAAWVA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AYTILATTMIAAADY
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]