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The map label for this gene is degQ [H]

Identifier: 110833676

GI number: 110833676

Start: 909252

End: 910655

Strand: Direct

Name: degQ [H]

Synonym: ABO_0815

Alternate gene names: 110833676

Gene position: 909252-910655 (Clockwise)

Preceding gene: 110833675

Following gene: 110833677

Centisome position: 29.14

GC content: 54.06

Gene sequence:

>1404_bases
TTGTTTGAAAAAACGTTGTCTATGAAAAATAAGCCGAGTCTTTCTCTTGTCTGTGTGCTGATGTTGTTATACCTGGCCTT
TTCCCCGGTTCATGCGGCCTTGCCTGCCGTCACCGCTGAAGGCGATGCGCTTCCCTCTCTGGCCCCCATGCTGGAGAAAA
CCTCCCCGGCGGTGGTCAATATCGCTATCGAAACCCGGGTGAGGGCAGCGCGAAACCCATTAATGGATGACCCTTTCTTT
CGCCGGTTCTTCAATATACCGGAACAACAGCGGCCTGCAGAGCGCCGTGCGGTTAGTGCCGGCTCCGGGGTCATTGTGGA
TGCTAGAGAAGGTTATGTGCTGACCAATGCCCATGTGGTTAAGAATGCTGACAACATTGAAGTCACTCTCACTGATGGAC
GTGAACTGTCGGCGGAGCTGGTGGGAGTGGATGATGAAGTGGATCTTGCCGTACTTAAACTCGAAGATGCGGAGCGCCTG
ACTCAGATTGCGATTGCTGATTCCACAGGCTTGCGGGTGGGTGATTTTGTGGTGGCCATCGGCAACCCCTTTGGGCTTGG
GCAAACGGTGACCAGCGGTATCGTGTCTGCACTGGGGCGTACTGGTCTTGGCATTGAAGGGTACGAGAGCTTTATTCAGA
CCGATGCCTCCATTAATCCTGGGAACTCTGGTGGGGCGCTGGTTAATCTGAACGGCGAGTTGGTCGGTATAAATACCGCC
ATTTTGGCCCCAGCCGGCGGTAATGTGGGCATCGGTTTTGCCATCCCCACGGAGATGGCCGAAAACGTGATGCAGCAGTT
GATTGAACACGGTGAAGTACGCCGTGGCATGCTTGGTGTCACCATTCAGGACTTAACGGCTGAATTGGCTGAAGCCTTTG
GTGTAGAGCGCCAGCGTGGTGTAGTCATTACTCAAGTGGTTGAAGATAGTGCGGCAGAGAAAGCGGGTTTGAAAAGTGGT
GACGTCGTTACTGCCGTGGACGGCCGCCCGGTAAACCGAGCCGCGGACCTGCGCAATAAAGTGGGTATGGCTCCGGTGGG
CGAGAAGGTCACTCTCAGTATCCTCCGTGAGGGTAACAAGAGAAATATTACTGCTGTGATTAGCGAGTTATCGCGGGAAA
CCGCAGGTGGTGAGGTGGTTTCCAAATTCCTGGAAGGTGCCAATCTGCGCGACTTGAGAAAAGGCGAATTGCAACATGCC
GACACGGGCGTGCTGGTGGACGAAGTAGAACGAGGCTCTCCCGCCTGGCGTGCCGGGTTGCGTAAAGGTGATGTGATCAT
CAACGTGAATCGACAGGATGTTGAAACCATGGACGGATTACGTAAAGCGGTGGACGATAAAGAAGCTGCCCTGTTGTTGC
GGGTTAACCGCAATGGTGGCGTTTTCTTTGTGGTAGTGCGCTAA

Upstream 100 bases:

>100_bases
CCGCTTTGTGCTACAAGCATTTCTGGGTGTCATCCGCTACTGCCTTTAGCTCATCATCGTTTTTAACGATGATGTTTCCT
TGCAACAGGAGGAACAACCG

Downstream 100 bases:

>100_bases
TCGACGGTCGGTAGCGCCGACAAAAAAGCCGGCAATCAGTGCCGGCTTTTTTGTCTCTTATTTTCCGTAGGTCGGCTTAG
CTGTAGCTGTATGCTGACAG

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MFEKTLSMKNKPSLSLVCVLMLLYLAFSPVHAALPAVTAEGDALPSLAPMLEKTSPAVVNIAIETRVRAARNPLMDDPFF
RRFFNIPEQQRPAERRAVSAGSGVIVDAREGYVLTNAHVVKNADNIEVTLTDGRELSAELVGVDDEVDLAVLKLEDAERL
TQIAIADSTGLRVGDFVVAIGNPFGLGQTVTSGIVSALGRTGLGIEGYESFIQTDASINPGNSGGALVNLNGELVGINTA
ILAPAGGNVGIGFAIPTEMAENVMQQLIEHGEVRRGMLGVTIQDLTAELAEAFGVERQRGVVITQVVEDSAAEKAGLKSG
DVVTAVDGRPVNRAADLRNKVGMAPVGEKVTLSILREGNKRNITAVISELSRETAGGEVVSKFLEGANLRDLRKGELQHA
DTGVLVDEVERGSPAWRAGLRKGDVIINVNRQDVETMDGLRKAVDDKEAALLLRVNRNGGVFFVVVR

Sequences:

>Translated_467_residues
MFEKTLSMKNKPSLSLVCVLMLLYLAFSPVHAALPAVTAEGDALPSLAPMLEKTSPAVVNIAIETRVRAARNPLMDDPFF
RRFFNIPEQQRPAERRAVSAGSGVIVDAREGYVLTNAHVVKNADNIEVTLTDGRELSAELVGVDDEVDLAVLKLEDAERL
TQIAIADSTGLRVGDFVVAIGNPFGLGQTVTSGIVSALGRTGLGIEGYESFIQTDASINPGNSGGALVNLNGELVGINTA
ILAPAGGNVGIGFAIPTEMAENVMQQLIEHGEVRRGMLGVTIQDLTAELAEAFGVERQRGVVITQVVEDSAAEKAGLKSG
DVVTAVDGRPVNRAADLRNKVGMAPVGEKVTLSILREGNKRNITAVISELSRETAGGEVVSKFLEGANLRDLRKGELQHA
DTGVLVDEVERGSPAWRAGLRKGDVIINVNRQDVETMDGLRKAVDDKEAALLLRVNRNGGVFFVVVR
>Mature_467_residues
MFEKTLSMKNKPSLSLVCVLMLLYLAFSPVHAALPAVTAEGDALPSLAPMLEKTSPAVVNIAIETRVRAARNPLMDDPFF
RRFFNIPEQQRPAERRAVSAGSGVIVDAREGYVLTNAHVVKNADNIEVTLTDGRELSAELVGVDDEVDLAVLKLEDAERL
TQIAIADSTGLRVGDFVVAIGNPFGLGQTVTSGIVSALGRTGLGIEGYESFIQTDASINPGNSGGALVNLNGELVGINTA
ILAPAGGNVGIGFAIPTEMAENVMQQLIEHGEVRRGMLGVTIQDLTAELAEAFGVERQRGVVITQVVEDSAAEKAGLKSG
DVVTAVDGRPVNRAADLRNKVGMAPVGEKVTLSILREGNKRNITAVISELSRETAGGEVVSKFLEGANLRDLRKGELQHA
DTGVLVDEVERGSPAWRAGLRKGDVIINVNRQDVETMDGLRKAVDDKEAALLLRVNRNGGVFFVVVR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=338, Percent_Identity=34.9112426035503, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI24308541, Length=286, Percent_Identity=35.6643356643357, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI22129776, Length=341, Percent_Identity=31.6715542521994, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI7019477, Length=314, Percent_Identity=35.6687898089172, Blast_Score=142, Evalue=5e-34,
Organism=Escherichia coli, GI1789629, Length=455, Percent_Identity=48.3516483516484, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1786356, Length=453, Percent_Identity=47.682119205298, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1789630, Length=339, Percent_Identity=38.6430678466077, Blast_Score=204, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24646839, Length=288, Percent_Identity=32.9861111111111, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49654; Mature: 49654

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKTLSMKNKPSLSLVCVLMLLYLAFSPVHAALPAVTAEGDALPSLAPMLEKTSPAVVN
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCEECCCCCCCHHHHHHHCCCCEEEE
IAIETRVRAARNPLMDDPFFRRFFNIPEQQRPAERRAVSAGSGVIVDAREGYVLTNAHVV
EEEHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCEEEECCEEE
KNADNIEVTLTDGRELSAELVGVDDEVDLAVLKLEDAERLTQIAIADSTGLRVGDFVVAI
ECCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECCHHHHHEEEEECCCCCEECEEEEEE
GNPFGLGQTVTSGIVSALGRTGLGIEGYESFIQTDASINPGNSGGALVNLNGELVGINTA
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEE
ILAPAGGNVGIGFAIPTEMAENVMQQLIEHGEVRRGMLGVTIQDLTAELAEAFGVERQRG
EEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHCEEHHHHHHHHHHHHCCCCCCC
VVITQVVEDSAAEKAGLKSGDVVTAVDGRPVNRAADLRNKVGMAPVGEKVTLSILREGNK
EEEEEEHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCC
RNITAVISELSRETAGGEVVSKFLEGANLRDLRKGELQHADTGVLVDEVERGSPAWRAGL
CHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHCC
RKGDVIINVNRQDVETMDGLRKAVDDKEAALLLRVNRNGGVFFVVVR
CCCCEEEEECHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MFEKTLSMKNKPSLSLVCVLMLLYLAFSPVHAALPAVTAEGDALPSLAPMLEKTSPAVVN
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCEECCCCCCCHHHHHHHCCCCEEEE
IAIETRVRAARNPLMDDPFFRRFFNIPEQQRPAERRAVSAGSGVIVDAREGYVLTNAHVV
EEEHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHCCCCCEEEECCCCEEEECCEEE
KNADNIEVTLTDGRELSAELVGVDDEVDLAVLKLEDAERLTQIAIADSTGLRVGDFVVAI
ECCCCEEEEEECCCCCCEEEECCCCCCCEEEEEECCHHHHHEEEEECCCCCEECEEEEEE
GNPFGLGQTVTSGIVSALGRTGLGIEGYESFIQTDASINPGNSGGALVNLNGELVGINTA
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEE
ILAPAGGNVGIGFAIPTEMAENVMQQLIEHGEVRRGMLGVTIQDLTAELAEAFGVERQRG
EEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHCEEHHHHHHHHHHHHCCCCCCC
VVITQVVEDSAAEKAGLKSGDVVTAVDGRPVNRAADLRNKVGMAPVGEKVTLSILREGNK
EEEEEEHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCC
RNITAVISELSRETAGGEVVSKFLEGANLRDLRKGELQHADTGVLVDEVERGSPAWRAGL
CHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHCC
RKGDVIINVNRQDVETMDGLRKAVDDKEAALLLRVNRNGGVFFVVVR
CCCCEEEEECHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]