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The map label for this gene is nudL [H]

Identifier: 110833652

GI number: 110833652

Start: 885920

End: 886411

Strand: Direct

Name: nudL [H]

Synonym: ABO_0791

Alternate gene names: 110833652

Gene position: 885920-886411 (Clockwise)

Preceding gene: 110833650

Following gene: 110833653

Centisome position: 28.39

GC content: 50.61

Gene sequence:

>492_bases
ATGCCGTTAGTGGATGTGCCTGACCCCCAGATCATCCTGACGGTTCGCTCCAATTCCATGCCCACTCATGCGGGCGAAGT
GGCCTTTCCTGGAGGCAAGCGGGATCCAGGCGACAAAGATTTGTTGATGACCGCTTTGCGAGAAAGCGAAGAAGAAGTTG
GGTTGTCACCGGATTATGTGGATGTGCTCGGGCAATTATCTCCCTTGGCGTCCCGTTATGGTATGAAAGTGACGCCCTTT
GTGGGCATTGTTCGTCCTGACGTGGAGCTGCAAGCGGAGCCCGGCGAGATTGACACGATTTTTCAGGTTCCCTTGCAGTT
TTTCCTGGATGAGATACCAGAGCTTTCCAGTCCTATCGATGTGTTTGGTCGCCAGTTTCGTATTCCCAGCTATTACTATG
AAGACAAGCGTATTTGGGGGCTAACCGCCTTCATGATTCTGGACTTGATTAACCATGTTTATGACGCAGGCATTGAGTTC
GAAGTGAAATAA

Upstream 100 bases:

>100_bases
TTGTGAATTGGAGAAGGGTGTGCTTGAGCAGCTCAGGCAGCGTTTGCCGGATTACAGACGCACAGAATTGTCCCTGGCCT
TACCTGAGGCCGCTGTTTTA

Downstream 100 bases:

>100_bases
CCCGCCGCTGGGTATCAGTAAAAAGGGGAAAGGCATGATTTATAAGATTGGTGAGCGTCGCTTAGAGCAACGTGGTGATG
GCCACTGGATAGCGGATAAC

Product: MutT/nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MPLVDVPDPQIILTVRSNSMPTHAGEVAFPGGKRDPGDKDLLMTALRESEEEVGLSPDYVDVLGQLSPLASRYGMKVTPF
VGIVRPDVELQAEPGEIDTIFQVPLQFFLDEIPELSSPIDVFGRQFRIPSYYYEDKRIWGLTAFMILDLINHVYDAGIEF
EVK

Sequences:

>Translated_163_residues
MPLVDVPDPQIILTVRSNSMPTHAGEVAFPGGKRDPGDKDLLMTALRESEEEVGLSPDYVDVLGQLSPLASRYGMKVTPF
VGIVRPDVELQAEPGEIDTIFQVPLQFFLDEIPELSSPIDVFGRQFRIPSYYYEDKRIWGLTAFMILDLINHVYDAGIEF
EVK
>Mature_162_residues
PLVDVPDPQIILTVRSNSMPTHAGEVAFPGGKRDPGDKDLLMTALRESEEEVGLSPDYVDVLGQLSPLASRYGMKVTPFV
GIVRPDVELQAEPGEIDTIFQVPLQFFLDEIPELSSPIDVFGRQFRIPSYYYEDKRIWGLTAFMILDLINHVYDAGIEFE
VK

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=160, Percent_Identity=35, Blast_Score=93, Evalue=1e-19,
Organism=Escherichia coli, GI1788115, Length=151, Percent_Identity=40.3973509933775, Blast_Score=88, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17510677, Length=142, Percent_Identity=33.8028169014084, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536993, Length=174, Percent_Identity=30.4597701149425, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18859683, Length=138, Percent_Identity=31.8840579710145, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 18300; Mature: 18169

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVDVPDPQIILTVRSNSMPTHAGEVAFPGGKRDPGDKDLLMTALRESEEEVGLSPDYV
CCCCCCCCCEEEEEECCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
DVLGQLSPLASRYGMKVTPFVGIVRPDVELQAEPGEIDTIFQVPLQFFLDEIPELSSPID
HHHHHHHHHHHHCCCEECCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHH
VFGRQFRIPSYYYEDKRIWGLTAFMILDLINHVYDAGIEFEVK
HHHHEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure 
PLVDVPDPQIILTVRSNSMPTHAGEVAFPGGKRDPGDKDLLMTALRESEEEVGLSPDYV
CCCCCCCCEEEEEECCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
DVLGQLSPLASRYGMKVTPFVGIVRPDVELQAEPGEIDTIFQVPLQFFLDEIPELSSPID
HHHHHHHHHHHHCCCEECCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHH
VFGRQFRIPSYYYEDKRIWGLTAFMILDLINHVYDAGIEFEVK
HHHHEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]