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The map label for this gene is dctM [H]

Identifier: 110833551

GI number: 110833551

Start: 766004

End: 767293

Strand: Direct

Name: dctM [H]

Synonym: ABO_0690

Alternate gene names: 110833551

Gene position: 766004-767293 (Clockwise)

Preceding gene: 110833550

Following gene: 110833557

Centisome position: 24.55

GC content: 51.71

Gene sequence:

>1290_bases
ATGATTACAGCGGCGATTATCCTGCTGGTGGTATTGGCGTTAATGGGCGCGCCTTTGTTTGCCATTATTCTTGGCGCGGC
AGCACTGGGGTTTTATACCCTAGAGATTGAGTTGGCAGTGCTGCACATCGATATCTATCAGCTCAGCAATTCTGTGGTGC
TGATGGCATTGCCATTGTTTACGTTTGCGGGTTTTCTGCTGAGTGAATCGAAAACCGCTGATCGTATGTTGCGGCTAAGC
CAAGCCGCCTTCGGCTGGATGCCCGGTGGCATGGCTTTTGTAGCGTTGATTGCCTGTGCTTTTTTTACCGCTTTAACCGG
CGGCTCTGGCGTCACTATTGTGGCATTAGGGGCGCTGTTGCTGCCCGCGCTGGTGAAAGGCAATTACCCGGAAAAATTTA
GCTTGGGTCTGGTGACCTCTTCAGGGAGTTTGGGCTTGCTATTGGTGCCGTCTGTGCCCCTGTTGATCTACGGCATTATT
GCTCAGCAAATGTCTCAGCAATTGGACATGCCCACAGTGGAGATTGTCGATCTGTATCTGGCTGGCCTATTGCCCGCATT
GCTGATGATCGTGCTACTTTACGGCTACTGTGTGTGGGCTACCCGCGGCACCGATGTACCCCGGCAGGCGTTTGATTTCC
GTGAACTGGTGGATGCGTTATGGCAGGCTCGTTGGGAGCTGCCATTACCATTGGTGGTGCTGGGCGGAATCTTCTCCGGC
TTTTTAGTCATTAGTGAGGCGGCGGCGGTGACGGCGCTGTATGTGCTGGTGGCGGAGGTGTTTCTGTATCGGGAAATTTC
CCTGCGCAAGCTGCCGACAATTATGCGTGATTCCATGATCATGGTAGGCGGCATATTGTTGATTTTGGCGGTGGCGCAGG
CGTTTTCTGACTACTTGGTGTATGCCGGTGTGCCAGAGGAGCTATTTGCTCTAATCCAAACGCATGTGGAAAGCAAAATC
ACCTTCCTGATCCTGCTTAATATTTTGCTGCTGTTATTGGGCGCGTTACTGGATATTTTTGCGGCGCTGGTGATCATGGT
GCCACTGATTTTGCCGGTGGCGTTGCGCTACGGTATTGACCCTGTGCATCTGGGGATTATCTTCGTGGCGAACATGCAGA
TTGGCTATATCACCCCGCCGGTGGGTATGAATCTGTTTATTGCCAGTTACCGCTTCAAGAAGAAAGTTACGGAGCTGTTC
GCGGCAACCATTCCTTTCATGCTGATATTGATTATCGCTTTGTTAATGATTACCTATGTACCGCAGTTGAGCTTGTGGCT
GGTGCGCTGA

Upstream 100 bases:

>100_bases
CGATTATTCCAGTGGGCTTCTCGGTCATGGCCTTGCGCTATGTGGTGTTGTTTGCGATGGGGTTGATTGGTAAACGGCCG
AAGATGCAGGAGCTGACGCC

Downstream 100 bases:

>100_bases
TTTAAGCGGCACGTTGAGAGTGAAAAGTTGAAACGCGATCAGATTTTTTGCTGAGGCAGAGGTCAAAGAGGCCGCGCTCA
TTCTCCGAGCGCGGCCTCTT

Product: TRAP dicarboxylate transporter

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MITAAIILLVVLALMGAPLFAIILGAAALGFYTLEIELAVLHIDIYQLSNSVVLMALPLFTFAGFLLSESKTADRMLRLS
QAAFGWMPGGMAFVALIACAFFTALTGGSGVTIVALGALLLPALVKGNYPEKFSLGLVTSSGSLGLLLVPSVPLLIYGII
AQQMSQQLDMPTVEIVDLYLAGLLPALLMIVLLYGYCVWATRGTDVPRQAFDFRELVDALWQARWELPLPLVVLGGIFSG
FLVISEAAAVTALYVLVAEVFLYREISLRKLPTIMRDSMIMVGGILLILAVAQAFSDYLVYAGVPEELFALIQTHVESKI
TFLILLNILLLLLGALLDIFAALVIMVPLILPVALRYGIDPVHLGIIFVANMQIGYITPPVGMNLFIASYRFKKKVTELF
AATIPFMLILIIALLMITYVPQLSLWLVR

Sequences:

>Translated_429_residues
MITAAIILLVVLALMGAPLFAIILGAAALGFYTLEIELAVLHIDIYQLSNSVVLMALPLFTFAGFLLSESKTADRMLRLS
QAAFGWMPGGMAFVALIACAFFTALTGGSGVTIVALGALLLPALVKGNYPEKFSLGLVTSSGSLGLLLVPSVPLLIYGII
AQQMSQQLDMPTVEIVDLYLAGLLPALLMIVLLYGYCVWATRGTDVPRQAFDFRELVDALWQARWELPLPLVVLGGIFSG
FLVISEAAAVTALYVLVAEVFLYREISLRKLPTIMRDSMIMVGGILLILAVAQAFSDYLVYAGVPEELFALIQTHVESKI
TFLILLNILLLLLGALLDIFAALVIMVPLILPVALRYGIDPVHLGIIFVANMQIGYITPPVGMNLFIASYRFKKKVTELF
AATIPFMLILIIALLMITYVPQLSLWLVR
>Mature_429_residues
MITAAIILLVVLALMGAPLFAIILGAAALGFYTLEIELAVLHIDIYQLSNSVVLMALPLFTFAGFLLSESKTADRMLRLS
QAAFGWMPGGMAFVALIACAFFTALTGGSGVTIVALGALLLPALVKGNYPEKFSLGLVTSSGSLGLLLVPSVPLLIYGII
AQQMSQQLDMPTVEIVDLYLAGLLPALLMIVLLYGYCVWATRGTDVPRQAFDFRELVDALWQARWELPLPLVVLGGIFSG
FLVISEAAAVTALYVLVAEVFLYREISLRKLPTIMRDSMIMVGGILLILAVAQAFSDYLVYAGVPEELFALIQTHVESKI
TFLILLNILLLLLGALLDIFAALVIMVPLILPVALRYGIDPVHLGIIFVANMQIGYITPPVGMNLFIASYRFKKKVTELF
AATIPFMLILIIALLMITYVPQLSLWLVR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=405, Percent_Identity=27.4074074074074, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46582; Mature: 46582

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAAIILLVVLALMGAPLFAIILGAAALGFYTLEIELAVLHIDIYQLSNSVVLMALPLF
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEEEEEEEEHHHHCCCHHHHHHHHH
TFAGFLLSESKTADRMLRLSQAAFGWMPGGMAFVALIACAFFTALTGGSGVTIVALGALL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LPALVKGNYPEKFSLGLVTSSGSLGLLLVPSVPLLIYGIIAQQMSQQLDMPTVEIVDLYL
HHHHHCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGLLPALLMIVLLYGYCVWATRGTDVPRQAFDFRELVDALWQARWELPLPLVVLGGIFSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLVISEAAAVTALYVLVAEVFLYREISLRKLPTIMRDSMIMVGGILLILAVAQAFSDYLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YAGVPEELFALIQTHVESKITFLILLNILLLLLGALLDIFAALVIMVPLILPVALRYGID
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVHLGIIFVANMQIGYITPPVGMNLFIASYRFKKKVTELFAATIPFMLILIIALLMITYV
HHHHHEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PQLSLWLVR
CCHHHEECC
>Mature Secondary Structure
MITAAIILLVVLALMGAPLFAIILGAAALGFYTLEIELAVLHIDIYQLSNSVVLMALPLF
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEEEEEEEEHHHHCCCHHHHHHHHH
TFAGFLLSESKTADRMLRLSQAAFGWMPGGMAFVALIACAFFTALTGGSGVTIVALGALL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LPALVKGNYPEKFSLGLVTSSGSLGLLLVPSVPLLIYGIIAQQMSQQLDMPTVEIVDLYL
HHHHHCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AGLLPALLMIVLLYGYCVWATRGTDVPRQAFDFRELVDALWQARWELPLPLVVLGGIFSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLVISEAAAVTALYVLVAEVFLYREISLRKLPTIMRDSMIMVGGILLILAVAQAFSDYLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
YAGVPEELFALIQTHVESKITFLILLNILLLLLGALLDIFAALVIMVPLILPVALRYGID
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVHLGIIFVANMQIGYITPPVGMNLFIASYRFKKKVTELFAATIPFMLILIIALLMITYV
HHHHHEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PQLSLWLVR
CCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]