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The map label for this gene is glpG [H]

Identifier: 110833547

GI number: 110833547

Start: 762757

End: 763578

Strand: Direct

Name: glpG [H]

Synonym: ABO_0686

Alternate gene names: 110833547

Gene position: 762757-763578 (Clockwise)

Preceding gene: 110833546

Following gene: 110833548

Centisome position: 24.45

GC content: 56.81

Gene sequence:

>822_bases
ATGGAACTGATTCGTACCCCCCAGGTAGAGCTGGCGAATCTGATCGAACGCACCCTGAAACGCAATGGTTTTCAGGTGCA
CCGTCATGAGGATGAAGGTCAGTTCGTGCTGAGTGTGCCTGATGCTGAGCAATATCCCCATGCGCGAACACTGACCGCAG
AGCTGATTGCCGACCTGAAACGGGGGCAGGACCGACAAGCTGTGGAGCCTCTCACCGGCCAGCCACAGCCCTTGCTGTCT
GGTGGCTGGCTGGCCAGCATGGGTTGGGTGACCAAGCTTGGGCTGGGGTTGTGTGTGGCCATCTTCTTGACGCCTTATCT
AATGGGCGACGGGGTCTATCTTGCCCTGTTGTTTCCCGCGACCATGGAGGGGTTGACCAGCCAGCCATGGCGGTTGATCA
CTCCTATGCTGATGCACTTCTCCCTTCTCCATATCATTTTCAACTTGCTGTGGTGGGCAGATCTGGGGCGTCTGATTGAA
CGCCATCAATCGTCTGCCCAGCTGTTGCTGGTCACCCTGGTGACCTCAGCGGTTTCCAATGTGGCTCAGTTCTTATACAG
CGGGCCCATGTTCGGTGGCTTGTCCGGAGTGGTGTACGGTTTGTTGGGCTACCTATGGATCTTCGGGTGGCTGAATCCGG
GTGCCGGGTTTGCCCTGCGTCGGCAGATTGTGGTTTTTATGCTGGTATGGATGGTGATTTGTTTCGTAGGGCTATCGGAT
GTGGTGGCGAATGCGGCACATCTGGCAGGGCTGGTAAGCGGTTGTTTGTTGGGCGGCATTTTCGGCATGGTGCGGCGCAG
CCAGAAGCAAGGAGCAGTTTGA

Upstream 100 bases:

>100_bases
TTTCACAGTGCCAGCAGCAATGGGGCTGTTTCTGGCAGCAGGTAGATAACTTGTCTGATTTGGATGATGTACAACGCAAG
CAAGCCCTGGAGGCACTGGC

Downstream 100 bases:

>100_bases
GTTACCCCCGGTGGACTGCTATAAAGACAGCCAAAACGATGACGTTACAACAATGAAAGGATGTCAGCGACCTATGCAGT
GGCGCTCTGTACCCTATTGG

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MELIRTPQVELANLIERTLKRNGFQVHRHEDEGQFVLSVPDAEQYPHARTLTAELIADLKRGQDRQAVEPLTGQPQPLLS
GGWLASMGWVTKLGLGLCVAIFLTPYLMGDGVYLALLFPATMEGLTSQPWRLITPMLMHFSLLHIIFNLLWWADLGRLIE
RHQSSAQLLLVTLVTSAVSNVAQFLYSGPMFGGLSGVVYGLLGYLWIFGWLNPGAGFALRRQIVVFMLVWMVICFVGLSD
VVANAAHLAGLVSGCLLGGIFGMVRRSQKQGAV

Sequences:

>Translated_273_residues
MELIRTPQVELANLIERTLKRNGFQVHRHEDEGQFVLSVPDAEQYPHARTLTAELIADLKRGQDRQAVEPLTGQPQPLLS
GGWLASMGWVTKLGLGLCVAIFLTPYLMGDGVYLALLFPATMEGLTSQPWRLITPMLMHFSLLHIIFNLLWWADLGRLIE
RHQSSAQLLLVTLVTSAVSNVAQFLYSGPMFGGLSGVVYGLLGYLWIFGWLNPGAGFALRRQIVVFMLVWMVICFVGLSD
VVANAAHLAGLVSGCLLGGIFGMVRRSQKQGAV
>Mature_273_residues
MELIRTPQVELANLIERTLKRNGFQVHRHEDEGQFVLSVPDAEQYPHARTLTAELIADLKRGQDRQAVEPLTGQPQPLLS
GGWLASMGWVTKLGLGLCVAIFLTPYLMGDGVYLALLFPATMEGLTSQPWRLITPMLMHFSLLHIIFNLLWWADLGRLIE
RHQSSAQLLLVTLVTSAVSNVAQFLYSGPMFGGLSGVVYGLLGYLWIFGWLNPGAGFALRRQIVVFMLVWMVICFVGLSD
VVANAAHLAGLVSGCLLGGIFGMVRRSQKQGAV

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=184, Percent_Identity=40.2173913043478, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 30072; Mature: 30072

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIRTPQVELANLIERTLKRNGFQVHRHEDEGQFVLSVPDAEQYPHARTLTAELIADLK
CCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCHHHCCCHHHHHHHHHHHHH
RGQDRQAVEPLTGQPQPLLSGGWLASMGWVTKLGLGLCVAIFLTPYLMGDGVYLALLFPA
CCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TMEGLTSQPWRLITPMLMHFSLLHIIFNLLWWADLGRLIERHQSSAQLLLVTLVTSAVSN
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VAQFLYSGPMFGGLSGVVYGLLGYLWIFGWLNPGAGFALRRQIVVFMLVWMVICFVGLSD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVANAAHLAGLVSGCLLGGIFGMVRRSQKQGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELIRTPQVELANLIERTLKRNGFQVHRHEDEGQFVLSVPDAEQYPHARTLTAELIADLK
CCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCHHHCCCHHHHHHHHHHHHH
RGQDRQAVEPLTGQPQPLLSGGWLASMGWVTKLGLGLCVAIFLTPYLMGDGVYLALLFPA
CCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TMEGLTSQPWRLITPMLMHFSLLHIIFNLLWWADLGRLIERHQSSAQLLLVTLVTSAVSN
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VAQFLYSGPMFGGLSGVVYGLLGYLWIFGWLNPGAGFALRRQIVVFMLVWMVICFVGLSD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VVANAAHLAGLVSGCLLGGIFGMVRRSQKQGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA