Click here to switch to the map view.

The map label for this gene is murG

Identifier: 110833459

GI number: 110833459

Start: 655984

End: 657057

Strand: Direct

Name: murG

Synonym: ABO_0598

Alternate gene names: 110833459

Gene position: 655984-657057 (Clockwise)

Preceding gene: 110833458

Following gene: 110833460

Centisome position: 21.02

GC content: 62.29

Gene sequence:

>1074_bases
ATGAGTGGCACCGTCCTGATTATGGCTGGCGGTACGGGTGGGCATGTATTCCCTGCGCTGGCTGTGGCTGACCAACTGCG
CACCCGCGGTTTCGATATTCTCTGGCTGGGCGCGGAAAACGGCATGGAAGGCAACTTAGTGCGCCAGTATGGCTACGAAA
TTGCCGAATTGTCTGTGTCCCGCCTACGCGGTGGTGGCATCAAGCGTAAGTTGACCGCGCCGTTCAACCTGTTGCGGGCG
GTGTTACAGGCGCGGCAGCTGATTCGCGCCCGTCAGCCGGTGCTGGCGGTGGGCTTTGGTGGTTTTGCCAGCGGCCCCGG
TGGGCTGGCTGCGCGCTTGTGCAAGGTGCCGGTGGTGGTACATGAGCAGAATGCGGTTCCCGGGCTGACTAATCGCTTGT
TGTCTCGTTTATCGACGGTGACCCTGGAAGGGTTCCAGGGTGCTTTTGGTCACCCGCAAGCCTGCTGGGTGGGCAACCCG
GTACGTCCGCAGATTACTGCTCTAGAGGAGCCGGCTCGTCGTTATGCACAGCATCAGGGCGGGCTTCGTGTGCTGGTTCT
GGGCGGAAGCCAAGGGGCGCTGGTACTTAATCAGGATCTGCCGGAATTACTATTGGCGGTACTGGGTCGCGATATACAGG
TGCGCCATCAATGCGGCGCCGGGCGTACCGCTGAAGCTGCACCGATTTACCAGGCGCTGGGGCTGCAGGCTCAGGTGAGT
GAATTTATTGATGATATGGCAGAAGCCTACGGGTGGGCGGATTTGGTGATCTGCCGGGCCGGCGCACTGACCGTGGCGGA
AGTGGCCGCAGCGGGCGTGGCCGCCCTGTTTGTACCACTGCCCAGCGCAGTGGATGACCACCAGACATTGAACGCCCGTT
GGTTGTCAGAGCGCGGGGCTGCCCTGTTGCTGCCCCAACGGGACCTGGGTGCGGTAAGTCTTGCTGGCACCTTGAAACCG
GTTGCAGAGCGTGGCCTGTTGGCGCAAATCGCCGAGCGGGCCCGTGAGCAGGCGATGGCGGATAGTGCAGAGCGCGCCGC
CACGCTGTGTGAGGAGGTGGCCAATGGCCGATAA

Upstream 100 bases:

>100_bases
ATGGGGGGTCTTCCCTGTTGATTTCCGCCGTTATGGTGGGGCTGATTTTACGAGCCGGAGCGGAAGCGGACCACCTGAAA
GCCAGAGGGAGGGCTGCACG

Downstream 100 bases:

>100_bases
CGACATTATTCATACGGTGCCGGAGATGCGCCGCATTCGCGGTATCCACTTTGTGGGTATCGGCGGTGTGGGCATGTGCG
GCATTGCGGAAGTGCTGGCC

Product: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentap eptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSGTVLIMAGGTGGHVFPALAVADQLRTRGFDILWLGAENGMEGNLVRQYGYEIAELSVSRLRGGGIKRKLTAPFNLLRA
VLQARQLIRARQPVLAVGFGGFASGPGGLAARLCKVPVVVHEQNAVPGLTNRLLSRLSTVTLEGFQGAFGHPQACWVGNP
VRPQITALEEPARRYAQHQGGLRVLVLGGSQGALVLNQDLPELLLAVLGRDIQVRHQCGAGRTAEAAPIYQALGLQAQVS
EFIDDMAEAYGWADLVICRAGALTVAEVAAAGVAALFVPLPSAVDDHQTLNARWLSERGAALLLPQRDLGAVSLAGTLKP
VAERGLLAQIAERAREQAMADSAERAATLCEEVANGR

Sequences:

>Translated_357_residues
MSGTVLIMAGGTGGHVFPALAVADQLRTRGFDILWLGAENGMEGNLVRQYGYEIAELSVSRLRGGGIKRKLTAPFNLLRA
VLQARQLIRARQPVLAVGFGGFASGPGGLAARLCKVPVVVHEQNAVPGLTNRLLSRLSTVTLEGFQGAFGHPQACWVGNP
VRPQITALEEPARRYAQHQGGLRVLVLGGSQGALVLNQDLPELLLAVLGRDIQVRHQCGAGRTAEAAPIYQALGLQAQVS
EFIDDMAEAYGWADLVICRAGALTVAEVAAAGVAALFVPLPSAVDDHQTLNARWLSERGAALLLPQRDLGAVSLAGTLKP
VAERGLLAQIAERAREQAMADSAERAATLCEEVANGR
>Mature_356_residues
SGTVLIMAGGTGGHVFPALAVADQLRTRGFDILWLGAENGMEGNLVRQYGYEIAELSVSRLRGGGIKRKLTAPFNLLRAV
LQARQLIRARQPVLAVGFGGFASGPGGLAARLCKVPVVVHEQNAVPGLTNRLLSRLSTVTLEGFQGAFGHPQACWVGNPV
RPQITALEEPARRYAQHQGGLRVLVLGGSQGALVLNQDLPELLLAVLGRDIQVRHQCGAGRTAEAAPIYQALGLQAQVSE
FIDDMAEAYGWADLVICRAGALTVAEVAAAGVAALFVPLPSAVDDHQTLNARWLSERGAALLLPQRDLGAVSLAGTLKPV
AERGLLAQIAERAREQAMADSAERAATLCEEVANGR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=46.927374301676, Blast_Score=294, Evalue=6e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ALCBS (Q0VS02)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_692318.1
- ProteinModelPortal:   Q0VS02
- SMR:   Q0VS02
- STRING:   Q0VS02
- GeneID:   4211245
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_0598
- NMPDR:   fig|393595.12.peg.596
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   AKWINDM
- PhylomeDB:   Q0VS02
- BioCyc:   ABOR393595:ABO_0598-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37659; Mature: 37528

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTVLIMAGGTGGHVFPALAVADQLRTRGFDILWLGAENGMEGNLVRQYGYEIAELSVS
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHCCHHHHHHHH
RLRGGGIKRKLTAPFNLLRAVLQARQLIRARQPVLAVGFGGFASGPGGLAARLCKVPVVV
HHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCEEE
HEQNAVPGLTNRLLSRLSTVTLEGFQGAFGHPQACWVGNPVRPQITALEEPARRYAQHQG
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCC
GLRVLVLGGSQGALVLNQDLPELLLAVLGRDIQVRHQCGAGRTAEAAPIYQALGLQAQVS
CEEEEEEECCCCCEEECCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHH
EFIDDMAEAYGWADLVICRAGALTVAEVAAAGVAALFVPLPSAVDDHQTLNARWLSERGA
HHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
ALLLPQRDLGAVSLAGTLKPVAERGLLAQIAERAREQAMADSAERAATLCEEVANGR
EEEECCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGTVLIMAGGTGGHVFPALAVADQLRTRGFDILWLGAENGMEGNLVRQYGYEIAELSVS
CCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHCCHHHHHHHH
RLRGGGIKRKLTAPFNLLRAVLQARQLIRARQPVLAVGFGGFASGPGGLAARLCKVPVVV
HHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCEEE
HEQNAVPGLTNRLLSRLSTVTLEGFQGAFGHPQACWVGNPVRPQITALEEPARRYAQHQG
ECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCC
GLRVLVLGGSQGALVLNQDLPELLLAVLGRDIQVRHQCGAGRTAEAAPIYQALGLQAQVS
CEEEEEEECCCCCEEECCCHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHH
EFIDDMAEAYGWADLVICRAGALTVAEVAAAGVAALFVPLPSAVDDHQTLNARWLSERGA
HHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCC
ALLLPQRDLGAVSLAGTLKPVAERGLLAQIAERAREQAMADSAERAATLCEEVANGR
EEEECCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA