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The map label for this gene is clpB [H]

Identifier: 110833340

GI number: 110833340

Start: 519451

End: 522048

Strand: Direct

Name: clpB [H]

Synonym: ABO_0479

Alternate gene names: 110833340

Gene position: 519451-522048 (Clockwise)

Preceding gene: 110833339

Following gene: 110833342

Centisome position: 16.65

GC content: 56.43

Gene sequence:

>2598_bases
ATGCGAATGGATAAACTCACTGCCCGCCTGCAGGAAGCGCTGTCAGACGCGCAATCCTTGGCCGTGGGGCAGGGTAATAG
CACCATTGAGCCAGTTCATCTGATGTTGGCGTTGATGCAGCAGCAGGGAGGCGCCGCTCGGCCGTTGTTGGAAAAAGCAG
GCGCCAACGTTGCCGATGTGATTACCGCCCTGAACATGGCTGTGGACAAGCTGCCCACGGTGACTAACTTCAATGGTGAT
GTGCAGATGGGACAAGCCACCGGGCGGATGCTGAATATTGCCGACCGGGAAGCTCAGCAGCGCGGTGACCAGTATCTTTC
TACGGAAGTGGTGTTGCTGGCGGCCTGTGACGATAGCGGTGAGCTGGGTAAGCTGTTTAAGAATGCCGGCGTCACTCGTA
AGGTGCTGGCTGAAAAAATTGCTGAAGTACGAGGGGGCGAAACGGTGAACGATCCCAACGCGGAAGACAAACGTGAAGCG
CTAGATAAGTACACCGTGAACCTGACCGAGCGAGCGGAATCCGGCAAGCTTGACCCGGTGATCGGCCGGGACGACGAAAT
TCGCCGTACTATTCAGGTCTTGCAGCGTCGCACCAAGAACAACCCGGTATTGATCGGTGAGCCCGGGGTGGGCAAGACCG
CCATTGTCGAAGGCCTTGCTCAGCGTATTGTGAATGGCGAAGTCCCTGAAGGCTTGAAGGACAAGCAAGTGCTCTCGCTG
GATATGGCCGCGCTGATCGCGGGTGCTAAATATCGAGGAGAGTTCGAAGAGCGCTTGAAAGCGGTACTCAACGAGTTGGC
TAAGCAGGAAGGGCGCATCATTCTTTTCATTGATGAGCTGCATACCATGGTCGGCGCCGGCAAGGGTGAAGGGTCCATGG
ATGCGGGCAATATGCTCAAGCCGGCACTGGCTCGGGGTGAGCTGCACTGTGTGGGTGCTACCACGCTGGACGAATACCGG
CAGTACATTGAGAAAGATGCCGCGCTGGAGCGTCGTTTTCAGAAAGTGCTGGTGGATGAGCCCACGGTGGAAGACACCAT
TGCCATTCTGCGGGGCTTGAAAGAGCGTTACGAAGTTCACCATGGCGTGGACATCACCGATGGCGCCATCATTGCCGCTG
CTCGCTTGAGTCATCGCTACATTACCGATCGACAACTGCCGGATAAGGCCATTGATCTGATCGACGAGGCCGGCAGCCGT
ATCCGTATGGAAATCGACTCTATGCCGGAGGAAATGGACCGCCTAGATCGCCGTTTGATCCAGCTGAAAATGGAGCGTGA
AGCGCTGCGCAAGGAAGACGATGATGCCAGCCGCAAGCGGCTGGAAAAGCTGGAAGATGAGATTGATGAGCTGGAAAAAG
AGTACGCGGATCTAGAGGAAATTTGGCAGGCGGAGAAAGCCGCGTTGCAGGGCGCAGCCGAATATAAGGCGGAGCTGGAG
CAGGCTCGTGTGGAGCTGGAGCAGGCCCGTCGCGCCGGCGACCTGAGCCGTATGTCCGAACTGCAGTACGGCGAAATTCC
GGAACTGGAAAAGAAAGTTCAGGATGCCCAGGACCGGGAAGAACAAGCCCAAACTGAGACGCAGCTGCTGCGTAACAAGG
TCACCGACGAGGAAATTGCTGAGGTGGTGGCCAAGTGGACCGGCATTCCTGTATCGAAAATGTTGGAAGGTGAGAAAGAC
AAGTTGCTGCGTATGGAAGATGCCTTGCATGATCGGGTGGTCGGCCAGAATGAGGCTGTTGAGGCGGTGGCTAATGCGGT
ACGCCGCTCCCGGGCAGGGTTGTCAGATCCGAATCGACCCAACGGCAGCTTCCTGTTTCTGGGCCCCACCGGGGTGGGTA
AAACGGAACTTTGTAAGGCGCTGGCCAACTTCCTGTTCGACACCGAAGAGGCCATGGTTCGCATCGACATGTCTGAGTTT
ATGGAAAAACATTCCGTGGCTCGGCTGGTCGGTGCCCCTCCGGGCTATGTGGGTTATGAGGAAGGCGGCTACCTCACCGA
GTTAGTGCGACGTAAACCTTACTCGGTGGTGTTGCTGGACGAGGTGGAAAAAGCCCACCCGGATGTGTTCAACATTCTGT
TGCAGGTGCTCGATGATGGTCGCCTGACGGATGGCCAAGGCCGTACCGTGGACTTCCGCAATACTGTGGTGGTGATGACA
TCCAACCTGGGTTCTGATCTGATTCAGAAGCTGGCAGGTTCTGATGCCGAATCTGCTAGTGATTATGAAACGATGAAATC
GGCGGTGATGGAGGTGGTAGGTAACCACTTCCGCCCGGAGTTCCTCAACCGAGTAGATGAAACCGTGGTGTTCCATCCGC
TGGCCAAAGATCAGCTCAAGGGCATTGCGTCCATTCAGTTGGGTTTCTTGCGCAAGCGATTGGCGGAGCGGGAAATGAGC
CTGGAGCTGAGTGATGCGGCGCTTGATCAGCTGGTGGATGCCGGTTTTGATCCCGTCTACGGGGCTCGTCCGCTTAAGCG
GGCTATCCAGCAGCAGTTGGAAAATCCGCTGGCTCAATCGCTGCTGAAAGGCGAGTACGTTCAGGGCGATACCATTCACG
TGGATGTGGAAGAGGGGCGGTTTACGTTTGGCCGTTAA

Upstream 100 bases:

>100_bases
GGACCCATCTATGATTCAGTTGATAGATAACCGGTGATCACATTGGCCTTGCCGACAGGGAGGCGTTGTGTGGATCACGA
CCGGATAGGAGAGCGATACA

Downstream 100 bases:

>100_bases
TCGTCCCTTTGGGCCAAGTAAAGAAAAGCCGCCGGTGGTAACGCCGGCGGCTTTTTTGTGGGCGGGCTTTTAGTCTCAGC
TTAGCGGCCTTCGCATTTCT

Product: ATP-dependent Clp protease, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MRMDKLTARLQEALSDAQSLAVGQGNSTIEPVHLMLALMQQQGGAARPLLEKAGANVADVITALNMAVDKLPTVTNFNGD
VQMGQATGRMLNIADREAQQRGDQYLSTEVVLLAACDDSGELGKLFKNAGVTRKVLAEKIAEVRGGETVNDPNAEDKREA
LDKYTVNLTERAESGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKQVLSL
DMAALIAGAKYRGEFEERLKAVLNELAKQEGRIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEVHHGVDITDGAIIAAARLSHRYITDRQLPDKAIDLIDEAGSR
IRMEIDSMPEEMDRLDRRLIQLKMEREALRKEDDDASRKRLEKLEDEIDELEKEYADLEEIWQAEKAALQGAAEYKAELE
QARVELEQARRAGDLSRMSELQYGEIPELEKKVQDAQDREEQAQTETQLLRNKVTDEEIAEVVAKWTGIPVSKMLEGEKD
KLLRMEDALHDRVVGQNEAVEAVANAVRRSRAGLSDPNRPNGSFLFLGPTGVGKTELCKALANFLFDTEEAMVRIDMSEF
MEKHSVARLVGAPPGYVGYEEGGYLTELVRRKPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVVMT
SNLGSDLIQKLAGSDAESASDYETMKSAVMEVVGNHFRPEFLNRVDETVVFHPLAKDQLKGIASIQLGFLRKRLAEREMS
LELSDAALDQLVDAGFDPVYGARPLKRAIQQQLENPLAQSLLKGEYVQGDTIHVDVEEGRFTFGR

Sequences:

>Translated_865_residues
MRMDKLTARLQEALSDAQSLAVGQGNSTIEPVHLMLALMQQQGGAARPLLEKAGANVADVITALNMAVDKLPTVTNFNGD
VQMGQATGRMLNIADREAQQRGDQYLSTEVVLLAACDDSGELGKLFKNAGVTRKVLAEKIAEVRGGETVNDPNAEDKREA
LDKYTVNLTERAESGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKQVLSL
DMAALIAGAKYRGEFEERLKAVLNELAKQEGRIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEVHHGVDITDGAIIAAARLSHRYITDRQLPDKAIDLIDEAGSR
IRMEIDSMPEEMDRLDRRLIQLKMEREALRKEDDDASRKRLEKLEDEIDELEKEYADLEEIWQAEKAALQGAAEYKAELE
QARVELEQARRAGDLSRMSELQYGEIPELEKKVQDAQDREEQAQTETQLLRNKVTDEEIAEVVAKWTGIPVSKMLEGEKD
KLLRMEDALHDRVVGQNEAVEAVANAVRRSRAGLSDPNRPNGSFLFLGPTGVGKTELCKALANFLFDTEEAMVRIDMSEF
MEKHSVARLVGAPPGYVGYEEGGYLTELVRRKPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVVMT
SNLGSDLIQKLAGSDAESASDYETMKSAVMEVVGNHFRPEFLNRVDETVVFHPLAKDQLKGIASIQLGFLRKRLAEREMS
LELSDAALDQLVDAGFDPVYGARPLKRAIQQQLENPLAQSLLKGEYVQGDTIHVDVEEGRFTFGR
>Mature_865_residues
MRMDKLTARLQEALSDAQSLAVGQGNSTIEPVHLMLALMQQQGGAARPLLEKAGANVADVITALNMAVDKLPTVTNFNGD
VQMGQATGRMLNIADREAQQRGDQYLSTEVVLLAACDDSGELGKLFKNAGVTRKVLAEKIAEVRGGETVNDPNAEDKREA
LDKYTVNLTERAESGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKQVLSL
DMAALIAGAKYRGEFEERLKAVLNELAKQEGRIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEVHHGVDITDGAIIAAARLSHRYITDRQLPDKAIDLIDEAGSR
IRMEIDSMPEEMDRLDRRLIQLKMEREALRKEDDDASRKRLEKLEDEIDELEKEYADLEEIWQAEKAALQGAAEYKAELE
QARVELEQARRAGDLSRMSELQYGEIPELEKKVQDAQDREEQAQTETQLLRNKVTDEEIAEVVAKWTGIPVSKMLEGEKD
KLLRMEDALHDRVVGQNEAVEAVANAVRRSRAGLSDPNRPNGSFLFLGPTGVGKTELCKALANFLFDTEEAMVRIDMSEF
MEKHSVARLVGAPPGYVGYEEGGYLTELVRRKPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVVMT
SNLGSDLIQKLAGSDAESASDYETMKSAVMEVVGNHFRPEFLNRVDETVVFHPLAKDQLKGIASIQLGFLRKRLAEREMS
LELSDAALDQLVDAGFDPVYGARPLKRAIQQQLENPLAQSLLKGEYVQGDTIHVDVEEGRFTFGR

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=323, Percent_Identity=38.6996904024768, Blast_Score=217, Evalue=3e-56,
Organism=Escherichia coli, GI1788943, Length=862, Percent_Identity=70.5336426914153, Blast_Score=1241, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=386, Percent_Identity=41.4507772020725, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6320464, Length=711, Percent_Identity=55.2742616033755, Blast_Score=793, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=869, Percent_Identity=42.1173762945915, Blast_Score=674, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96084; Mature: 96084

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMDKLTARLQEALSDAQSLAVGQGNSTIEPVHLMLALMQQQGGAARPLLEKAGANVADV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHH
ITALNMAVDKLPTVTNFNGDVQMGQATGRMLNIADREAQQRGDQYLSTEVVLLAACDDSG
HHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCC
ELGKLFKNAGVTRKVLAEKIAEVRGGETVNDPNAEDKREALDKYTVNLTERAESGKLDPV
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
IGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKQVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DMAALIAGAKYRGEFEERLKAVLNELAKQEGRIILFIDELHTMVGAGKGEGSMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHH
PALARGELHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEVH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDGAIIAAARLSHRYITDRQLPDKAIDLIDEAGSRIRMEIDSMPEEMDRLDRRLI
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHCCHHHHHHHHHHHH
QLKMEREALRKEDDDASRKRLEKLEDEIDELEKEYADLEEIWQAEKAALQGAAEYKAELE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARVELEQARRAGDLSRMSELQYGEIPELEKKVQDAQDREEQAQTETQLLRNKVTDEEIA
HHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EVVAKWTGIPVSKMLEGEKDKLLRMEDALHDRVVGQNEAVEAVANAVRRSRAGLSDPNRP
HHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
NGSFLFLGPTGVGKTELCKALANFLFDTEEAMVRIDMSEFMEKHSVARLVGAPPGYVGYE
CCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGYLTELVRRKPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVVMT
CCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEE
SNLGSDLIQKLAGSDAESASDYETMKSAVMEVVGNHFRPEFLNRVDETVVFHPLAKDQLK
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCHHHHH
GIASIQLGFLRKRLAEREMSLELSDAALDQLVDAGFDPVYGARPLKRAIQQQLENPLAQS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGEYVQGDTIHVDVEEGRFTFGR
HHCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MRMDKLTARLQEALSDAQSLAVGQGNSTIEPVHLMLALMQQQGGAARPLLEKAGANVADV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHH
ITALNMAVDKLPTVTNFNGDVQMGQATGRMLNIADREAQQRGDQYLSTEVVLLAACDDSG
HHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCC
ELGKLFKNAGVTRKVLAEKIAEVRGGETVNDPNAEDKREALDKYTVNLTERAESGKLDPV
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
IGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKQVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DMAALIAGAKYRGEFEERLKAVLNELAKQEGRIILFIDELHTMVGAGKGEGSMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHH
PALARGELHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEVH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDGAIIAAARLSHRYITDRQLPDKAIDLIDEAGSRIRMEIDSMPEEMDRLDRRLI
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEHHCCHHHHHHHHHHHH
QLKMEREALRKEDDDASRKRLEKLEDEIDELEKEYADLEEIWQAEKAALQGAAEYKAELE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARVELEQARRAGDLSRMSELQYGEIPELEKKVQDAQDREEQAQTETQLLRNKVTDEEIA
HHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EVVAKWTGIPVSKMLEGEKDKLLRMEDALHDRVVGQNEAVEAVANAVRRSRAGLSDPNRP
HHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
NGSFLFLGPTGVGKTELCKALANFLFDTEEAMVRIDMSEFMEKHSVARLVGAPPGYVGYE
CCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGYLTELVRRKPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVVMT
CCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEE
SNLGSDLIQKLAGSDAESASDYETMKSAVMEVVGNHFRPEFLNRVDETVVFHPLAKDQLK
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCHHHHH
GIASIQLGFLRKRLAEREMSLELSDAALDQLVDAGFDPVYGARPLKRAIQQQLENPLAQS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGEYVQGDTIHVDVEEGRFTFGR
HHCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]