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The map label for this gene is glk

Identifier: 110635920

GI number: 110635920

Start: 3875989

End: 3877017

Strand: Reverse

Name: glk

Synonym: Meso_3594

Alternate gene names: 110635920

Gene position: 3877017-3875989 (Counterclockwise)

Preceding gene: 110635921

Following gene: 110635919

Centisome position: 87.87

GC content: 63.75

Gene sequence:

>1029_bases
ATGGCGTATTCCACCGACCATGACGTGGTGCTCGATTTCCCGATTTTGATCGGTGACATCGGCGGCACCAATGCGCGCTT
CGCCATTGTCGTGGACTCCTATGCCGAGCCGCGGGAATTTCCCGTCGTACAGACGGCCGATTTCGCAACGATAGAGGACG
CCATCCAGACGGCGATCCTTGACCAGACGCATCTCATTCCGCGCTCCGCCGTCCTGGCGGTTGCGGGACCCGTGAACGGA
GACGAAATCGATCTCACCAATTCAAATTGGGTGGTCCGGCCGCGCGAGATGATGGCCCATCTGGGTTTCAGCGATATCGT
CGTACTCAACGATTTCGAGGCGCAGGCGCTGGCTGTCGTGGCGCTTGGGGAAGAGCATCTGGAAAAGATTGGCGGCAACG
TCGCCGAAACCGTCGGGAGCCGCGTCGTCCTGGGGCCGGGGACCGGCCTCGGCGTGGCTGGCCTGGTGCACGCGCGCCGA
ACCTGGATCCCCGTTCCGGGCGAGGGCGGCCATATGGATCTTGGACCAAGGACAGCGCGCGACGAGCAGATCTTCCCGCA
TCTGGAGCGGATCGAGGGGAGGGTTTCCGGCGAACAGGTGCTTTGCGGGCGCGGTCTCGTCAACCTCTACCGTGCGATCG
CAAAGGCGGATGCCAAGGAGGCTGCTTTCTCCTCGCCCGCTGAGATTACGACGGCCGGGCTGGCGCAGGCCGATGAGATC
GCGGTTGAGACCCTGAACCTCTTCGTGACCTATCTCGGCAGGGTCGCGGGTGATCTCGGTCTTGTGTTCATGAGCCGGGG
CGGAGTGTTCCTGACAGGAGGCATCGCCCAGAAGATCGTGCCGGCGCTGAAGAACAGCCTGTTCCGCGCCGCCTTTGAAG
ACAAGGCGCCGCACAATGAACTGATGGCGTCCATGCCGGTTTATGTCATCACCCATCCGCTGGCCGCGCTGCACGGGCTT
GCGGCCTATGCCCGAACGCCAGCGCGCTTCGGCGTCGAAACGGCGGGCCGGCGCTGGCGCTTGCGCTGA

Upstream 100 bases:

>100_bases
ATTCCAATGGCGTTGAACCGGGCCACGGCCGAAAATATTCTTGCCTTGGAAGAGGCGGCAGGCCCGGAGCCGATAGTTGA
GCAAGGAGGCTCCTAGCCCG

Downstream 100 bases:

>100_bases
GGGCAGCGGCGCCTTTTGCCCTGCTGCGATTGCATATGTGCCTTTGATCGGGCATAGGCTGCTGCGAGCAATGCCGGTGT
GCAGAGCCGGCGGCAGCATA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAYSTDHDVVLDFPILIGDIGGTNARFAIVVDSYAEPREFPVVQTADFATIEDAIQTAILDQTHLIPRSAVLAVAGPVNG
DEIDLTNSNWVVRPREMMAHLGFSDIVVLNDFEAQALAVVALGEEHLEKIGGNVAETVGSRVVLGPGTGLGVAGLVHARR
TWIPVPGEGGHMDLGPRTARDEQIFPHLERIEGRVSGEQVLCGRGLVNLYRAIAKADAKEAAFSSPAEITTAGLAQADEI
AVETLNLFVTYLGRVAGDLGLVFMSRGGVFLTGGIAQKIVPALKNSLFRAAFEDKAPHNELMASMPVYVITHPLAALHGL
AAYARTPARFGVETAGRRWRLR

Sequences:

>Translated_342_residues
MAYSTDHDVVLDFPILIGDIGGTNARFAIVVDSYAEPREFPVVQTADFATIEDAIQTAILDQTHLIPRSAVLAVAGPVNG
DEIDLTNSNWVVRPREMMAHLGFSDIVVLNDFEAQALAVVALGEEHLEKIGGNVAETVGSRVVLGPGTGLGVAGLVHARR
TWIPVPGEGGHMDLGPRTARDEQIFPHLERIEGRVSGEQVLCGRGLVNLYRAIAKADAKEAAFSSPAEITTAGLAQADEI
AVETLNLFVTYLGRVAGDLGLVFMSRGGVFLTGGIAQKIVPALKNSLFRAAFEDKAPHNELMASMPVYVITHPLAALHGL
AAYARTPARFGVETAGRRWRLR
>Mature_341_residues
AYSTDHDVVLDFPILIGDIGGTNARFAIVVDSYAEPREFPVVQTADFATIEDAIQTAILDQTHLIPRSAVLAVAGPVNGD
EIDLTNSNWVVRPREMMAHLGFSDIVVLNDFEAQALAVVALGEEHLEKIGGNVAETVGSRVVLGPGTGLGVAGLVHARRT
WIPVPGEGGHMDLGPRTARDEQIFPHLERIEGRVSGEQVLCGRGLVNLYRAIAKADAKEAAFSSPAEITTAGLAQADEIA
VETLNLFVTYLGRVAGDLGLVFMSRGGVFLTGGIAQKIVPALKNSLFRAAFEDKAPHNELMASMPVYVITHPLAALHGLA
AYARTPARFGVETAGRRWRLR

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=312, Percent_Identity=40.0641025641026, Blast_Score=215, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_MESSB (Q11CB2)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_676128.1
- ProteinModelPortal:   Q11CB2
- SMR:   Q11CB2
- STRING:   Q11CB2
- GeneID:   4182193
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3594
- NMPDR:   fig|266779.1.peg.942
- eggNOG:   COG0837
- HOGENOM:   HBG644410
- OMA:   VDIGGTH
- PhylomeDB:   Q11CB2
- ProtClustDB:   PRK00292
- BioCyc:   MSP266779:MESO_3594-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 36572; Mature: 36441

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSTDHDVVLDFPILIGDIGGTNARFAIVVDSYAEPREFPVVQTADFATIEDAIQTAIL
CCCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHHHHHH
DQTHLIPRSAVLAVAGPVNGDEIDLTNSNWVVRPREMMAHLGFSDIVVLNDFEAQALAVV
HHHHCCCCCEEEEEECCCCCCEEEECCCCCEECHHHHHHHCCCCEEEEEECCCCCEEEEE
ALGEEHLEKIGGNVAETVGSRVVLGPGTGLGVAGLVHARRTWIPVPGEGGHMDLGPRTAR
EECHHHHHHHCCHHHHHHCCEEEECCCCCCHHHHHHHHHHCEEECCCCCCCCCCCCCCCC
DEQIFPHLERIEGRVSGEQVLCGRGLVNLYRAIAKADAKEAAFSSPAEITTAGLAQADEI
CCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCHHHHH
AVETLNLFVTYLGRVAGDLGLVFMSRGGVFLTGGIAQKIVPALKNSLFRAAFEDKAPHNE
HHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHH
LMASMPVYVITHPLAALHGLAAYARTPARFGVETAGRRWRLR
HHHHCCHHHHHHHHHHHHHHHHHHCCCHHHCHHCCCCEECCC
>Mature Secondary Structure 
AYSTDHDVVLDFPILIGDIGGTNARFAIVVDSYAEPREFPVVQTADFATIEDAIQTAIL
CCCCCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHHHHHH
DQTHLIPRSAVLAVAGPVNGDEIDLTNSNWVVRPREMMAHLGFSDIVVLNDFEAQALAVV
HHHHCCCCCEEEEEECCCCCCEEEECCCCCEECHHHHHHHCCCCEEEEEECCCCCEEEEE
ALGEEHLEKIGGNVAETVGSRVVLGPGTGLGVAGLVHARRTWIPVPGEGGHMDLGPRTAR
EECHHHHHHHCCHHHHHHCCEEEECCCCCCHHHHHHHHHHCEEECCCCCCCCCCCCCCCC
DEQIFPHLERIEGRVSGEQVLCGRGLVNLYRAIAKADAKEAAFSSPAEITTAGLAQADEI
CCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHCCHHHHH
AVETLNLFVTYLGRVAGDLGLVFMSRGGVFLTGGIAQKIVPALKNSLFRAAFEDKAPHNE
HHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHH
LMASMPVYVITHPLAALHGLAAYARTPARFGVETAGRRWRLR
HHHHCCHHHHHHHHHHHHHHHHHHCCCHHHCHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA