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The map label for this gene is glmS [C]

Identifier: 110635881

GI number: 110635881

Start: 3827988

End: 3828980

Strand: Reverse

Name: glmS [C]

Synonym: Meso_3554

Alternate gene names: 110635881

Gene position: 3828980-3827988 (Counterclockwise)

Preceding gene: 110635882

Following gene: 110635879

Centisome position: 86.78

GC content: 63.34

Gene sequence:

>993_bases
ATGAGTTACCGTTCCACGATAGCCCGCCAGCCCGAAGCGCTGGCCGACACCTATGCAGCCGCTAGCGAGCAGCTTGCCGG
GATGGATCTGGCGTCGCTCGACAGGCCGGTGATCGGAATTACGGGCATCGGCGCCAGCTTTGCCGCGGCGGTGGTTGGCG
CCGGCGAGCTGCAAGCGCAGCGGCGACGTGCCTTCGCGATCCGCGCCTGCGATATGGCCGAAGGGCGTAACCTGGTCGAC
GCGCTTGTGGGCCTGTCCCATCGCGGCCGCAGCGTCGAGACGGTCCTGGCGCATGAGAAGCTTGCATCTGCAAAGCGCCT
GGCGATCACAAATGATCCGGCGAGCCCGCTGGCGCGGGCTTCCGACCTGCATCTCACGTTGAACAACGGCTCGGACGCGA
CCCCATCGAGCACGGGCTACACTGCAACGCTTTTGGCTATGGGTATGGCGTTTGAGAAGATGACCGGAGGAGCTCGCGGC
GACTTCGCGTCGATCCCTGAACTCGCGCGGGAGATGCTCGCCAACGCATCCGTAAAGATGAAGCGGCTGCGCGAACTGTT
TCATCAGCGCCGCGCCATCGACTGCGTCGGGGCAGGCGCATCGCTGGGCACCGCCGACGGAGCATCGCTGCTGATCAGGG
AGGCGGCACGCATTCCCGCATCGGCCTACGATACACGCCATTATCTCCACGGTCCGCTCGAATCTATGGATGGGACCACC
GGCGTGGTCATCTTCGGCGATGGTCGGGAAATCGAGCTGGCGCACCAGGTGGAGAAAATCGGATGTCCCGTCCTGCTCGT
TACCACCGACGCCTCTGTGAAGGACGGGGATCTGCTGACCGTCATTACCGTTCCGAAGCAGTCGAACCAGATCGCGCAAG
GCATCCTGAACATCCTGGCGCCTCAGCTGTTCGCCGCGGAACTATCGGACGCGGCTAACCTCACCGATACCAAGTTCCGT
TACCGCATGAACGACACGAAAGTGCCAGCGTAA

Upstream 100 bases:

>100_bases
GGGGCATGCCGTCTCGCCGCGATGCTTTCTAATTCTTTGCCCGGCCGGCGGAACTCCTACCCGGCCACGGCGCGAACCTG
ACCAAAAAGAAGGAAATCCG

Downstream 100 bases:

>100_bases
TCCCGAGGGCGCCAATACGCACTTGAGGAGATGCCCAGCGGCCCACGGCAGACGCACTGCTGCTCGGAGGCAAAGGGTCC
GTGTTTGGACAGCTGTCCGT

Product: sugar isomerase (SIS)

Products: D-Glucosamine 6-phosphate; L-Glutamate [C]

Alternate protein names: Glutamine-Fructose-6-Phosphate Transaminase; Sugar Isomerase Domain-Containing Protein; SIS Domain Protein

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSYRSTIARQPEALADTYAAASEQLAGMDLASLDRPVIGITGIGASFAAAVVGAGELQAQRRRAFAIRACDMAEGRNLVD
ALVGLSHRGRSVETVLAHEKLASAKRLAITNDPASPLARASDLHLTLNNGSDATPSSTGYTATLLAMGMAFEKMTGGARG
DFASIPELAREMLANASVKMKRLRELFHQRRAIDCVGAGASLGTADGASLLIREAARIPASAYDTRHYLHGPLESMDGTT
GVVIFGDGREIELAHQVEKIGCPVLLVTTDASVKDGDLLTVITVPKQSNQIAQGILNILAPQLFAAELSDAANLTDTKFR
YRMNDTKVPA

Sequences:

>Translated_330_residues
MSYRSTIARQPEALADTYAAASEQLAGMDLASLDRPVIGITGIGASFAAAVVGAGELQAQRRRAFAIRACDMAEGRNLVD
ALVGLSHRGRSVETVLAHEKLASAKRLAITNDPASPLARASDLHLTLNNGSDATPSSTGYTATLLAMGMAFEKMTGGARG
DFASIPELAREMLANASVKMKRLRELFHQRRAIDCVGAGASLGTADGASLLIREAARIPASAYDTRHYLHGPLESMDGTT
GVVIFGDGREIELAHQVEKIGCPVLLVTTDASVKDGDLLTVITVPKQSNQIAQGILNILAPQLFAAELSDAANLTDTKFR
YRMNDTKVPA
>Mature_329_residues
SYRSTIARQPEALADTYAAASEQLAGMDLASLDRPVIGITGIGASFAAAVVGAGELQAQRRRAFAIRACDMAEGRNLVDA
LVGLSHRGRSVETVLAHEKLASAKRLAITNDPASPLARASDLHLTLNNGSDATPSSTGYTATLLAMGMAFEKMTGGARGD
FASIPELAREMLANASVKMKRLRELFHQRRAIDCVGAGASLGTADGASLLIREAARIPASAYDTRHYLHGPLESMDGTTG
VVIFGDGREIELAHQVEKIGCPVLLVTTDASVKDGDLLTVITVPKQSNQIAQGILNILAPQLFAAELSDAANLTDTKFRY
RMNDTKVPA

Specific function: Catalyzes The First Step In Hexosamine Metabolism, Converting Fructose-6p Into Glucosamine-6p Using Glutamine As A Nitrogen Source. [C]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.6.1.16 [C]

Molecular weight: Translated: 34857; Mature: 34726

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRSTIARQPEALADTYAAASEQLAGMDLASLDRPVIGITGIGASFAAAVVGAGELQAQ
CCCHHHHHCCCHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCHHHHHHHHCCHHHHHH
RRRAFAIRACDMAEGRNLVDALVGLSHRGRSVETVLAHEKLASAKRLAITNDPASPLARA
HHHHHHHEECCHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHCC
SDLHLTLNNGSDATPSSTGYTATLLAMGMAFEKMTGGARGDFASIPELAREMLANASVKM
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHH
KRLRELFHQRRAIDCVGAGASLGTADGASLLIREAARIPASAYDTRHYLHGPLESMDGTT
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCHHHHCCCHHHCCCCC
GVVIFGDGREIELAHQVEKIGCPVLLVTTDASVKDGDLLTVITVPKQSNQIAQGILNILA
EEEEEECCCEEHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
PQLFAAELSDAANLTDTKFRYRMNDTKVPA
HHHHHHHHHHCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SYRSTIARQPEALADTYAAASEQLAGMDLASLDRPVIGITGIGASFAAAVVGAGELQAQ
CCHHHHHCCCHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECCCHHHHHHHHCCHHHHHH
RRRAFAIRACDMAEGRNLVDALVGLSHRGRSVETVLAHEKLASAKRLAITNDPASPLARA
HHHHHHHEECCHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHCC
SDLHLTLNNGSDATPSSTGYTATLLAMGMAFEKMTGGARGDFASIPELAREMLANASVKM
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHH
KRLRELFHQRRAIDCVGAGASLGTADGASLLIREAARIPASAYDTRHYLHGPLESMDGTT
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCHHHHCCCHHHCCCCC
GVVIFGDGREIELAHQVEKIGCPVLLVTTDASVKDGDLLTVITVPKQSNQIAQGILNILA
EEEEEECCCEEHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
PQLFAAELSDAANLTDTKFRYRMNDTKVPA
HHHHHHHHHHCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): 1140 [C]

Specific activity: NA

Km value (mM): 0.65 {glutamine}} 2 {fructose} [C]

Substrates: D-Fructose 6-phosphate; L-Glutamine [C]

Specific reaction: D-Fructose 6-phosphate + L-Glutamine --> D-Glucosamine 6-phosphate + L-Glutamate [C]

General reaction: Amino group transfer [C]

Inhibitor: 5, 5'-Dithiobis (2-nitrobenzoate); 6-Diazo-5-oxo-L-norleucine; Anticapsin; Azaserine; Dithiodiformamidine; Dithiodinicotinic acid; Iodoacetamide; N-Ethyl maleimide; N3-(4-Methoxyfumaroyl)-L-2, 3-diaminopropanoic acid [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA