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The map label for this gene is tesA [C]

Identifier: 110635678

GI number: 110635678

Start: 3619905

End: 3620585

Strand: Reverse

Name: tesA [C]

Synonym: Meso_3350

Alternate gene names: 110635678

Gene position: 3620585-3619905 (Counterclockwise)

Preceding gene: 110635683

Following gene: 110635677

Centisome position: 82.05

GC content: 60.35

Gene sequence:

>681_bases
ATGGCAATCAAATTCTTGGGCAAGTTTTTAGCCGCTGTCTCGCCCCTCGCGAAAATGTTATCGGCGGCGGCCGCTCTTTT
CGTCGTTTTGGCCGCCCAACTGCCCGCCCAGGCGGAGCCTTTCAACATCGTCGGCTTCGGCGACAGCCTGATGGCAGGAT
ATGAGCTCGGCCCCGGCGAAGGCTTCACGGACAGGTTGCAAGCCGCGCTGCGCGAGCGCGGCCATGAGGTGACAGTCGCA
AACGCCGGGGTGTCGGGCGATACAACGAGTGGCGGACTGTCGCGTTTGGACTGGTCCGTGCCCGACGGCACCGACCTGGT
GATCCTCGAACTCGGCGCAAACGATATGCTGCGCGGCGTCGCGCCCGCTTCCACGGAAAAGAACCTGGAAGAGATCATCA
CAAGGCTAAAGGCGCGGGACATAAGGATTCTGCTGGTCGGAATGTATGCCGCTCCAAATCTCGGGCCTGACTACCAACAG
GCCTTCAATTCCATCTATCCGCGGCTTGCGGAAAAACACGAGCTGCCGCTTGTGCCCTTCTTCCTCGAGGGCGTTGCCGG
AAACGCATCGCTCCAGCTCGCCGATGGAATGCATCCCAACGCGCAGGGGATCGATCTCATGGTGAAGAACGTTCTGCCCG
AGGTGGAACTCCTTCTTCAGGGGGACAAGCCGAACATGTGA

Upstream 100 bases:

>100_bases
CAGGGAAACGTCTTTCAGGTCTATCACCGGTGCAGTCACGTTTGGGGCGTCCTATATGTGAGGGGTAGCGTGGGGCGTGA
TCAGATATGGGTTGGATTCC

Downstream 100 bases:

>100_bases
GGGGAGAGCGGGAGAAACCGCTTGCCCCAACACTCAATCGATGATTCGCTGATGGTGACATAGCGAATCGAGGAGGTTGC
CATGCCGCGACTTTTCACCG

Product: lipolytic enzyme, G-D-S-L

Products: NA

Alternate protein names: Aryl-ester hydrolase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MAIKFLGKFLAAVSPLAKMLSAAAALFVVLAAQLPAQAEPFNIVGFGDSLMAGYELGPGEGFTDRLQAALRERGHEVTVA
NAGVSGDTTSGGLSRLDWSVPDGTDLVILELGANDMLRGVAPASTEKNLEEIITRLKARDIRILLVGMYAAPNLGPDYQQ
AFNSIYPRLAEKHELPLVPFFLEGVAGNASLQLADGMHPNAQGIDLMVKNVLPEVELLLQGDKPNM

Sequences:

>Translated_226_residues
MAIKFLGKFLAAVSPLAKMLSAAAALFVVLAAQLPAQAEPFNIVGFGDSLMAGYELGPGEGFTDRLQAALRERGHEVTVA
NAGVSGDTTSGGLSRLDWSVPDGTDLVILELGANDMLRGVAPASTEKNLEEIITRLKARDIRILLVGMYAAPNLGPDYQQ
AFNSIYPRLAEKHELPLVPFFLEGVAGNASLQLADGMHPNAQGIDLMVKNVLPEVELLLQGDKPNM
>Mature_225_residues
AIKFLGKFLAAVSPLAKMLSAAAALFVVLAAQLPAQAEPFNIVGFGDSLMAGYELGPGEGFTDRLQAALRERGHEVTVAN
AGVSGDTTSGGLSRLDWSVPDGTDLVILELGANDMLRGVAPASTEKNLEEIITRLKARDIRILLVGMYAAPNLGPDYQQA
FNSIYPRLAEKHELPLVPFFLEGVAGNASLQLADGMHPNAQGIDLMVKNVLPEVELLLQGDKPNM

Specific function: Favors the hydrolysis of several arylesters [H]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786702, Length=195, Percent_Identity=36.4102564102564, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =3.1.1.2 [H]

Molecular weight: Translated: 24022; Mature: 23891

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKFLGKFLAAVSPLAKMLSAAAALFVVLAAQLPAQAEPFNIVGFGDSLMAGYELGPGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCCCCCCCC
GFTDRLQAALRERGHEVTVANAGVSGDTTSGGLSRLDWSVPDGTDLVILELGANDMLRGV
CHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCHHHHCC
APASTEKNLEEIITRLKARDIRILLVGMYAAPNLGPDYQQAFNSIYPRLAEKHELPLVPF
CCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
FLEGVAGNASLQLADGMHPNAQGIDLMVKNVLPEVELLLQGDKPNM
HHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure 
AIKFLGKFLAAVSPLAKMLSAAAALFVVLAAQLPAQAEPFNIVGFGDSLMAGYELGPGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCCCCCCCC
GFTDRLQAALRERGHEVTVANAGVSGDTTSGGLSRLDWSVPDGTDLVILELGANDMLRGV
CHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCHHHHCC
APASTEKNLEEIITRLKARDIRILLVGMYAAPNLGPDYQQAFNSIYPRLAEKHELPLVPF
CCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
FLEGVAGNASLQLADGMHPNAQGIDLMVKNVLPEVELLLQGDKPNM
HHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8141782 [H]