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The map label for this gene is sdhB [H]

Identifier: 110635572

GI number: 110635572

Start: 3510254

End: 3511033

Strand: Reverse

Name: sdhB [H]

Synonym: Meso_3243

Alternate gene names: 110635572

Gene position: 3511033-3510254 (Counterclockwise)

Preceding gene: 110635573

Following gene: 110635571

Centisome position: 79.57

GC content: 60.64

Gene sequence:

>780_bases
ATGGTCCAACTTACTCTTCCCAAGAACTCGAAGGTCAAGCAAGGCAAGGTCTGGCCGAAGCCGGAAGGCGCCACAAACCT
GCGCGAATACCGCATCTATCGCTGGTCGCCGGACGATACGGAAAATCCGCGCGTCGACACCTATTATGTCGACCTCGACG
ATTGCGGGCCGATGGTGCTGGACGGGCTCATCTGGATCAAGAACAAGGTCGATTCGACGCTCACCTTCCGCCGGTCGTGC
CGGGAAGGCATCTGCGGTTCATGCGCCATGAATATCGACGGCGCGAACACGCTTGCCTGCACCAAGGGCATGGACGACAT
CGGTGGTGCCGTGCGGGTCTATCCCCTGCCGCATATGCCAGTGGTGAAGGATTTGGTGCCGGATCTCTCGATCCCCTATG
CGCAGCTTTCCTCGATCGAGCCGTGGCTTCAGACGGTCACGCCGGAACCCGCGATCGAGTGGAAGCAAAGCCATGAGGAC
CGGGCGAAGCTCGATGGACTCTACGAGTGCATCCTCTGCTTCTGCTGCCAGACCTCGTGCCCCAGCTATTGGTGGAACGG
CGAGCGCTATCTGGGGCCTGCCGTGCTGCTCCAGGCCTATCGCTGGCTGATCGATTCGCGCGACGAGGCTACAGGCGAGC
GGCTCGACAAGCTGGAGGATCCCTTCCGGCTTTATCGCTGCCACACGATCATGAACTGCACGCAGACCTGCCCGAAGGGG
CTCAATCCGGCGAAGGCGATCGCCGAGATAAAGAAGATGATGGTGGAGCGGCGGGTTTGA

Upstream 100 bases:

>100_bases
CGCCCGGTGCATACTGAGCCGATGCTGAAGCCCGAGAATGGCGGCATCGATCCGGCAAGGATCGCGCCGAAGAAGCGCGT
ATACTGAGGCAGAGGACATC

Downstream 100 bases:

>100_bases
TACCGGCGCCCTCAGGCGCGGCGATCTATTTGGCGCTGTGATCCCTTCCCGCCACTCACGCAACCGTGTAGGGGCGAGAG
TTTGCAGCGGGAACTCTTCG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVQLTLPKNSKVKQGKVWPKPEGATNLREYRIYRWSPDDTENPRVDTYYVDLDDCGPMVLDGLIWIKNKVDSTLTFRRSC
REGICGSCAMNIDGANTLACTKGMDDIGGAVRVYPLPHMPVVKDLVPDLSIPYAQLSSIEPWLQTVTPEPAIEWKQSHED
RAKLDGLYECILCFCCQTSCPSYWWNGERYLGPAVLLQAYRWLIDSRDEATGERLDKLEDPFRLYRCHTIMNCTQTCPKG
LNPAKAIAEIKKMMVERRV

Sequences:

>Translated_259_residues
MVQLTLPKNSKVKQGKVWPKPEGATNLREYRIYRWSPDDTENPRVDTYYVDLDDCGPMVLDGLIWIKNKVDSTLTFRRSC
REGICGSCAMNIDGANTLACTKGMDDIGGAVRVYPLPHMPVVKDLVPDLSIPYAQLSSIEPWLQTVTPEPAIEWKQSHED
RAKLDGLYECILCFCCQTSCPSYWWNGERYLGPAVLLQAYRWLIDSRDEATGERLDKLEDPFRLYRCHTIMNCTQTCPKG
LNPAKAIAEIKKMMVERRV
>Mature_259_residues
MVQLTLPKNSKVKQGKVWPKPEGATNLREYRIYRWSPDDTENPRVDTYYVDLDDCGPMVLDGLIWIKNKVDSTLTFRRSC
REGICGSCAMNIDGANTLACTKGMDDIGGAVRVYPLPHMPVVKDLVPDLSIPYAQLSSIEPWLQTVTPEPAIEWKQSHED
RAKLDGLYECILCFCCQTSCPSYWWNGERYLGPAVLLQAYRWLIDSRDEATGERLDKLEDPFRLYRCHTIMNCTQTCPKG
LNPAKAIAEIKKMMVERRV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=236, Percent_Identity=68.6440677966102, Blast_Score=339, Evalue=1e-93,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=51.2820512820513, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1790596, Length=223, Percent_Identity=31.390134529148, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17533915, Length=234, Percent_Identity=61.5384615384615, Blast_Score=304, Evalue=3e-83,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=64.6551724137931, Blast_Score=310, Evalue=2e-85,
Organism=Drosophila melanogaster, GI17137106, Length=247, Percent_Identity=62.753036437247, Blast_Score=330, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24643156, Length=233, Percent_Identity=63.519313304721, Blast_Score=309, Evalue=1e-84,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29571; Mature: 29571

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLTLPKNSKVKQGKVWPKPEGATNLREYRIYRWSPDDTENPRVDTYYVDLDDCGPMVL
CEEEECCCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCEEEEEEECCCCCHHHH
DGLIWIKNKVDSTLTFRRSCREGICGSCAMNIDGANTLACTKGMDDIGGAVRVYPLPHMP
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHHCCEEEEEECCCCC
VVKDLVPDLSIPYAQLSSIEPWLQTVTPEPAIEWKQSHEDRAKLDGLYECILCFCCQTSC
HHHHHCCCCCCCHHHHHCCCHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGERYLGPAVLLQAYRWLIDSRDEATGERLDKLEDPFRLYRCHTIMNCTQTCPKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKKMMVERRV
CCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQLTLPKNSKVKQGKVWPKPEGATNLREYRIYRWSPDDTENPRVDTYYVDLDDCGPMVL
CEEEECCCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCCCEEEEEEECCCCCHHHH
DGLIWIKNKVDSTLTFRRSCREGICGSCAMNIDGANTLACTKGMDDIGGAVRVYPLPHMP
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCHHHCCEEEEEECCCCC
VVKDLVPDLSIPYAQLSSIEPWLQTVTPEPAIEWKQSHEDRAKLDGLYECILCFCCQTSC
HHHHHCCCCCCCHHHHHCCCHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
PSYWWNGERYLGPAVLLQAYRWLIDSRDEATGERLDKLEDPFRLYRCHTIMNCTQTCPKG
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
LNPAKAIAEIKKMMVERRV
CCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA