Click here to switch to the map view.

The map label for this gene is plsC [C]

Identifier: 110635417

GI number: 110635417

Start: 3359498

End: 3360304

Strand: Reverse

Name: plsC [C]

Synonym: Meso_3088

Alternate gene names: 110635417

Gene position: 3360304-3359498 (Counterclockwise)

Preceding gene: 110635418

Following gene: 110635415

Centisome position: 76.16

GC content: 59.11

Gene sequence:

>807_bases
ATGCTCTTCCTCCGCTCGCTGTTTTTCAACATTGCCCTGTATCTGAATACCGTGATCCAGATGCTTCTCTGGGCTCCGAT
CTATTTCCTGTTGCCGCGGAAAAGTGCCTGGTTCGTGCCGAAATTCTGGGCAGCCTCCTGTTTGTGGCTCCATAAGGTGT
GTGCGGGCGCAAGGGCGGAAATCTCCGGCCTCGAAAATCTTCCCGAAGGCTCGTGCATTATTGCTCCGAAGCACCAGTCA
TTCTGGGACACGATCGCCTTTCTGCCCTGGATCCCCGACGCAGTTTACATCCTGAAGCGGGAACTCATGTGGATCCCGCT
TTTCGGCTGGTATGTGGCAAAGATGCGCATGATCCCTATCGATCGCGGGAGCCGCTCGAAGGCTCTGAAACAGGCGGTGA
AGATTGGCCGCGAGCGAATGCGGGAAAACCGGCAGCTCATCATCTATCCTGAGGGAACGCGCAGGCCGCCGGGCGCGGAG
CCTGCTTACAAATACGGCATCGTCGAGCTCTACACTCAGCTCCAAGTGCCCGTCGTGCCGGTTGCACATGTTGCTGGCCT
TTATTGGCCGCGACGGAAATTCATGCGTTATCCCGGCGTGATCCGCGCCCGATTTTTGCCTCCCATCGAGCCGGGGCTCC
CACGGGAGGAATTCCTGCGGCGCCTGATCGGGGAAACCGAGGCAGCTTGCGATGAGCTGCTCCTGGACGCGGCGCGTAGC
CCTGGCTCCCCACCACTCCCGCCGACCGCTGTTGCGCGTATCGAGCAGCTGAATAGAGAGGCTTCGGCTTCAAAGGAGCA
AACGTGA

Upstream 100 bases:

>100_bases
CACCGTCGCGCACAAATAAACTTCCGCTCTTTACATCGGGCCCGCTTGCGGTAACCAACAGCTGATGGTGGCGCCTCGCG
CCTTTCGATCGGGTTCCCGC

Downstream 100 bases:

>100_bases
AATTTACGGAAGGCATCCAGTCGCTATAGGCCTTTTGCTGGCTCGGCAATCCCGGCTGCCACAGCTTCCAGCCAGTGATC
GCGCAGTCCAAGCGCCCGTA

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; 2-Acylglycerophosphoethanolamine Acyltransferase; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLFLRSLFFNIALYLNTVIQMLLWAPIYFLLPRKSAWFVPKFWAASCLWLHKVCAGARAEISGLENLPEGSCIIAPKHQS
FWDTIAFLPWIPDAVYILKRELMWIPLFGWYVAKMRMIPIDRGSRSKALKQAVKIGRERMRENRQLIIYPEGTRRPPGAE
PAYKYGIVELYTQLQVPVVPVAHVAGLYWPRRKFMRYPGVIRARFLPPIEPGLPREEFLRRLIGETEAACDELLLDAARS
PGSPPLPPTAVARIEQLNREASASKEQT

Sequences:

>Translated_268_residues
MLFLRSLFFNIALYLNTVIQMLLWAPIYFLLPRKSAWFVPKFWAASCLWLHKVCAGARAEISGLENLPEGSCIIAPKHQS
FWDTIAFLPWIPDAVYILKRELMWIPLFGWYVAKMRMIPIDRGSRSKALKQAVKIGRERMRENRQLIIYPEGTRRPPGAE
PAYKYGIVELYTQLQVPVVPVAHVAGLYWPRRKFMRYPGVIRARFLPPIEPGLPREEFLRRLIGETEAACDELLLDAARS
PGSPPLPPTAVARIEQLNREASASKEQT
>Mature_268_residues
MLFLRSLFFNIALYLNTVIQMLLWAPIYFLLPRKSAWFVPKFWAASCLWLHKVCAGARAEISGLENLPEGSCIIAPKHQS
FWDTIAFLPWIPDAVYILKRELMWIPLFGWYVAKMRMIPIDRGSRSKALKQAVKIGRERMRENRQLIIYPEGTRRPPGAE
PAYKYGIVELYTQLQVPVVPVAHVAGLYWPRRKFMRYPGVIRARFLPPIEPGLPREEFLRRLIGETEAACDELLLDAARS
PGSPPLPPTAVARIEQLNREASASKEQT

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6041665, Length=178, Percent_Identity=31.4606741573034, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5453718, Length=166, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI15100175, Length=166, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564032, Length=237, Percent_Identity=24.4725738396624, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24641614, Length=184, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641612, Length=184, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 30771; Mature: 30771

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLRSLFFNIALYLNTVIQMLLWAPIYFLLPRKSAWFVPKFWAASCLWLHKVCAGARAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
ISGLENLPEGSCIIAPKHQSFWDTIAFLPWIPDAVYILKRELMWIPLFGWYVAKMRMIPI
HHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEECC
DRGSRSKALKQAVKIGRERMRENRQLIIYPEGTRRPPGAEPAYKYGIVELYTQLQVPVVP
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
VAHVAGLYWPRRKFMRYPGVIRARFLPPIEPGLPREEFLRRLIGETEAACDELLLDAARS
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
PGSPPLPPTAVARIEQLNREASASKEQT
CCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLFLRSLFFNIALYLNTVIQMLLWAPIYFLLPRKSAWFVPKFWAASCLWLHKVCAGARAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
ISGLENLPEGSCIIAPKHQSFWDTIAFLPWIPDAVYILKRELMWIPLFGWYVAKMRMIPI
HHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEECC
DRGSRSKALKQAVKIGRERMRENRQLIIYPEGTRRPPGAEPAYKYGIVELYTQLQVPVVP
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
VAHVAGLYWPRRKFMRYPGVIRARFLPPIEPGLPREEFLRRLIGETEAACDELLLDAARS
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
PGSPPLPPTAVARIEQLNREASASKEQT
CCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA