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The map label for this gene is argJ [H]

Identifier: 110635341

GI number: 110635341

Start: 3277919

End: 3279160

Strand: Reverse

Name: argJ [H]

Synonym: Meso_3012

Alternate gene names: 110635341

Gene position: 3279160-3277919 (Counterclockwise)

Preceding gene: 110635342

Following gene: 110635340

Centisome position: 74.32

GC content: 64.41

Gene sequence:

>1242_bases
ATGTCTTCTGTCGTCTCGCCGCTCGCGCCGAAACGTTATCCGAAAATGCCCGAAGTCGATGGCGTGCGGATTGCCGCTGC
CGAAGCCGGCATCAAATACAAGAACCGCAAGGACCTGATGGTCATGGTCTTCGACGAGGGGACAGCGGCGGCGGGCGTTT
TCACCCGCTCCAGATGCCCCTCGGCGCCGGTGGAGTTCTGCCGAAAAAATCTCGCCGGCGGCAAGGCGCGCGTGCTGGTG
GTCAATTCAGGCAACGCGAACGCTTTTACCGGAAAAAAGGGCCGGGAAACGACTGCCGCGACTGCGCTGGCCGCGGCCAA
GGCGGCGGGCGCCAGCGAGGACGAGGTGTTCCTCGCCTCGACCGGCGTGATCGGCGAGCCGCTCGATCCCAGAAAGTTCT
CGCATCTGTTGGGCGACCTCACGAAACGTGCCGAGCCCAAGGCCTGGGAAGAGGCGGCACGCGCGATCATGACGACGGAC
ACCTATCCGAAGCTTGTCACGGCGACGGCTCGGCTCGGAGAAGCGGAGGTGGTCATCAACGGGATTGCCAAGGGGGCCGG
CATGATCGCGCCGGATATGGCCACCATGCTCTCCTTCGTGGCGACGGACGCGCCAATCGCCGCGCCGGTGCTGCAAGAGC
TTCTTTCCAAGGCGACGTCGAAGACCTTCAACGCGGTGACGGTCGACAGCGACACCTCCACCAGCGACACGCTCATGCTT
TTTGCCACAGGTAAGGCCGCCGCGCGCGGTGCGCCGCAGATCACGGATGCCAAAGATCCGCGGCTTCAGGGCTTCCGCCG
CGCGCTAGGCAAGCTCCTGAAGACGCTGGCGCTGCAGGTGGTGCGCGACGGTGAAGGGGCGCGCAAGCAGGTGGAGGTGA
CGGTGACCGGCGCGCGCTCCTCGCGTTCGGCCAAGCGCATCGCCCTTTCGATCGCCAATTCGCCGCTGGTGAAGACAGCG
ATTGCCGGCGAGGATGCAAATTGGGGCCGCATCGTTATGGCGGTCGGCAAGGCCGGCGAACCAGCCGATCGCGATCTTCT
CTCGATATGGTTCGGCAACAGCCGTGTGGCCCATGAGGGCGAGCGGGACCCCGGCTATTCGGAAGAGGAAGTCTCTGCCT
ATATGAAGCGCGACGAAATCGATATCCGGGTCGACCTCGGGCTGGGCCGGGGCAAGGCCACGGTCTGGACCTGCGACCTC
ACCAAGGAGTATGTCGCCATCAATGGCGATTACAGGAGCTGA

Upstream 100 bases:

>100_bases
ATCGCGACGGGGTGTTTCCGCTGTTTCGGCTTGCGTCTGGCACGGGCTTGAGGCACACGGAAGCGCATCCCGAGTTCCTG
TGCTTTTTCCGGAATCGCCC

Downstream 100 bases:

>100_bases
TTTGGCGTGGAAAAAGAGGTGGTTGAGCGGCTGGCAACGATCCGCCGGTTCGAGGCGGCGGGATTTCGCGCCTGGCCGGC
CACCTCGGTGCAATATGACG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSSVVSPLAPKRYPKMPEVDGVRIAAAEAGIKYKNRKDLMVMVFDEGTAAAGVFTRSRCPSAPVEFCRKNLAGGKARVLV
VNSGNANAFTGKKGRETTAATALAAAKAAGASEDEVFLASTGVIGEPLDPRKFSHLLGDLTKRAEPKAWEEAARAIMTTD
TYPKLVTATARLGEAEVVINGIAKGAGMIAPDMATMLSFVATDAPIAAPVLQELLSKATSKTFNAVTVDSDTSTSDTLML
FATGKAAARGAPQITDAKDPRLQGFRRALGKLLKTLALQVVRDGEGARKQVEVTVTGARSSRSAKRIALSIANSPLVKTA
IAGEDANWGRIVMAVGKAGEPADRDLLSIWFGNSRVAHEGERDPGYSEEEVSAYMKRDEIDIRVDLGLGRGKATVWTCDL
TKEYVAINGDYRS

Sequences:

>Translated_413_residues
MSSVVSPLAPKRYPKMPEVDGVRIAAAEAGIKYKNRKDLMVMVFDEGTAAAGVFTRSRCPSAPVEFCRKNLAGGKARVLV
VNSGNANAFTGKKGRETTAATALAAAKAAGASEDEVFLASTGVIGEPLDPRKFSHLLGDLTKRAEPKAWEEAARAIMTTD
TYPKLVTATARLGEAEVVINGIAKGAGMIAPDMATMLSFVATDAPIAAPVLQELLSKATSKTFNAVTVDSDTSTSDTLML
FATGKAAARGAPQITDAKDPRLQGFRRALGKLLKTLALQVVRDGEGARKQVEVTVTGARSSRSAKRIALSIANSPLVKTA
IAGEDANWGRIVMAVGKAGEPADRDLLSIWFGNSRVAHEGERDPGYSEEEVSAYMKRDEIDIRVDLGLGRGKATVWTCDL
TKEYVAINGDYRS
>Mature_412_residues
SSVVSPLAPKRYPKMPEVDGVRIAAAEAGIKYKNRKDLMVMVFDEGTAAAGVFTRSRCPSAPVEFCRKNLAGGKARVLVV
NSGNANAFTGKKGRETTAATALAAAKAAGASEDEVFLASTGVIGEPLDPRKFSHLLGDLTKRAEPKAWEEAARAIMTTDT
YPKLVTATARLGEAEVVINGIAKGAGMIAPDMATMLSFVATDAPIAAPVLQELLSKATSKTFNAVTVDSDTSTSDTLMLF
ATGKAAARGAPQITDAKDPRLQGFRRALGKLLKTLALQVVRDGEGARKQVEVTVTGARSSRSAKRIALSIANSPLVKTAI
AGEDANWGRIVMAVGKAGEPADRDLLSIWFGNSRVAHEGERDPGYSEEEVSAYMKRDEIDIRVDLGLGRGKATVWTCDLT
KEYVAINGDYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=424, Percent_Identity=37.0283018867925, Blast_Score=240, Evalue=3e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 43762; Mature: 43631

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVVSPLAPKRYPKMPEVDGVRIAAAEAGIKYKNRKDLMVMVFDEGTAAAGVFTRSRCP
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCEEEEEECCCCCCCCEEECCCCC
SAPVEFCRKNLAGGKARVLVVNSGNANAFTGKKGRETTAATALAAAKAAGASEDEVFLAS
CCHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
TGVIGEPLDPRKFSHLLGDLTKRAEPKAWEEAARAIMTTDTYPKLVTATARLGEAEVVIN
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCHHHHHHHHCCCCEEEEE
GIAKGAGMIAPDMATMLSFVATDAPIAAPVLQELLSKATSKTFNAVTVDSDTSTSDTLML
EHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
FATGKAAARGAPQITDAKDPRLQGFRRALGKLLKTLALQVVRDGEGARKQVEVTVTGARS
EECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
SRSAKRIALSIANSPLVKTAIAGEDANWGRIVMAVGKAGEPADRDLLSIWFGNSRVAHEG
CCCHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCEECCCC
ERDPGYSEEEVSAYMKRDEIDIRVDLGLGRGKATVWTCDLTKEYVAINGDYRS
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCC
>Mature Secondary Structure 
SSVVSPLAPKRYPKMPEVDGVRIAAAEAGIKYKNRKDLMVMVFDEGTAAAGVFTRSRCP
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCEEEEEECCCCCCCCEEECCCCC
SAPVEFCRKNLAGGKARVLVVNSGNANAFTGKKGRETTAATALAAAKAAGASEDEVFLAS
CCHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
TGVIGEPLDPRKFSHLLGDLTKRAEPKAWEEAARAIMTTDTYPKLVTATARLGEAEVVIN
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCHHHHHHHHCCCCEEEEE
GIAKGAGMIAPDMATMLSFVATDAPIAAPVLQELLSKATSKTFNAVTVDSDTSTSDTLML
EHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
FATGKAAARGAPQITDAKDPRLQGFRRALGKLLKTLALQVVRDGEGARKQVEVTVTGARS
EECCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
SRSAKRIALSIANSPLVKTAIAGEDANWGRIVMAVGKAGEPADRDLLSIWFGNSRVAHEG
CCCHHEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCEECCCC
ERDPGYSEEEVSAYMKRDEIDIRVDLGLGRGKATVWTCDLTKEYVAINGDYRS
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]