Click here to switch to the map view.

The map label for this gene is nudG [H]

Identifier: 110635339

GI number: 110635339

Start: 3276722

End: 3277135

Strand: Reverse

Name: nudG [H]

Synonym: Meso_3010

Alternate gene names: 110635339

Gene position: 3277135-3276722 (Counterclockwise)

Preceding gene: 110635340

Following gene: 110635338

Centisome position: 74.27

GC content: 63.77

Gene sequence:

>414_bases
GTGGAAAGCGCCGGAAAACCAATCCTGCTCGTCGCTGCCTGCGCGCTGATCGATGCCGACGGCCGAATCCTCCTGGCCCA
GCGGCCGGAGGGCAAGTCCATGGCCGGGCTGTGGGAGTTTCCGGGCGGAAAGGTCGAGACCGGCGAGACGCCGGAGGAAA
CCCTCATCCGCGAGCTGCATGAGGAACTGGGCATCGAAACGAAGGTGGAGTGCCTGGCGCCGCTCACATTCGCGAGCCAT
TCCTATGAGACGTTCCACCTGCTCATGCCGCTTTATGTCTGCCGTCGTTTTCAGGGCATCCCCCAGTCACGCGAGGGACA
GGCGCTGAAATGGGTCCGCCCGCGGAACCTTCGTGACTACCCCATGCCGCCCGCTGACGAGCCGCTCATCCCCTTTCTGA
TCGATCTCCTCTGA

Upstream 100 bases:

>100_bases
CGAAGAGGATAATGAGAAAGCGCTGGCGCTTTATCGCTCGCTCGGCTTTGAAGCCGTATACCGGTACCATTACCGGCGAT
CGGCGCAGGAAGGCTGAGCT

Downstream 100 bases:

>100_bases
ACGTTAAATCTTCCTTCAGCGAAAGCTGAGAATTTTACGGGACGGGGGCAAGATCAGTTGCGTGATCTCGTCCAAAACGT
CTGCGATTTCGGGATCGCCT

Product: mutator MutT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MESAGKPILLVAACALIDADGRILLAQRPEGKSMAGLWEFPGGKVETGETPEETLIRELHEELGIETKVECLAPLTFASH
SYETFHLLMPLYVCRRFQGIPQSREGQALKWVRPRNLRDYPMPPADEPLIPFLIDLL

Sequences:

>Translated_137_residues
MESAGKPILLVAACALIDADGRILLAQRPEGKSMAGLWEFPGGKVETGETPEETLIRELHEELGIETKVECLAPLTFASH
SYETFHLLMPLYVCRRFQGIPQSREGQALKWVRPRNLRDYPMPPADEPLIPFLIDLL
>Mature_137_residues
MESAGKPILLVAACALIDADGRILLAQRPEGKSMAGLWEFPGGKVETGETPEETLIRELHEELGIETKVECLAPLTFASH
SYETFHLLMPLYVCRRFQGIPQSREGQALKWVRPRNLRDYPMPPADEPLIPFLIDLL

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=130, Percent_Identity=43.0769230769231, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1786288, Length=124, Percent_Identity=35.4838709677419, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-

Molecular weight: Translated: 15368; Mature: 15368

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAGKPILLVAACALIDADGRILLAQRPEGKSMAGLWEFPGGKVETGETPEETLIRELH
CCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCEEECCCCCHHHHHHHHH
EELGIETKVECLAPLTFASHSYETFHLLMPLYVCRRFQGIPQSREGQALKWVRPRNLRDY
HHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCC
PMPPADEPLIPFLIDLL
CCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MESAGKPILLVAACALIDADGRILLAQRPEGKSMAGLWEFPGGKVETGETPEETLIRELH
CCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCEEECCCCCHHHHHHHHH
EELGIETKVECLAPLTFASHSYETFHLLMPLYVCRRFQGIPQSREGQALKWVRPRNLRDY
HHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCC
PMPPADEPLIPFLIDLL
CCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]