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The map label for this gene is grx [H]

Identifier: 110635334

GI number: 110635334

Start: 3273832

End: 3274113

Strand: Reverse

Name: grx [H]

Synonym: Meso_3005

Alternate gene names: 110635334

Gene position: 3274113-3273832 (Counterclockwise)

Preceding gene: 110635335

Following gene: 110635333

Centisome position: 74.2

GC content: 59.22

Gene sequence:

>282_bases
ATGGCAGATGTGACGATCTATACCCGGATGGGCTGCGGTTATTGCGTGGCGGCCAAGCGGCTGCTCGAGCGCAAGGGCAT
TGCCTATACCGAGCAGGACGCCAGTTTCTCGCCCGAATTGCGCAAGGAAATGATCGGCCGGGCAAACGGGCGCTCCACCT
TTCCCCAGATTTTTATCGGGAATATTCATGTAGGCGGTTCTGACGATCTGCACGCGCTGGAGCGGGAAGGCAGGCTTGAC
GCCCTTCTGGAGGAACGGGACATCGTGGGGAGCAGTCGATGA

Upstream 100 bases:

>100_bases
GCGAGGTGGACGTGCTTACTTTTGCCCGTGCGCTCAAGGAGGACTTTGCGCCGGAGGATGCGCTAACTATATAGGCGGCC
AAACAAATGCGGATGACGTT

Downstream 100 bases:

>100_bases
CGGCCGTCCGCGTCGCTGCGCTGCAGATGCGCTCCGGCACGGAGCCGGAGGCAAATCTTTCCGCTTTTGAAGCGCTTGTG
CGTGAAGCGGCGGCCCGAGG

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 93; Mature: 92

Protein sequence:

>93_residues
MADVTIYTRMGCGYCVAAKRLLERKGIAYTEQDASFSPELRKEMIGRANGRSTFPQIFIGNIHVGGSDDLHALEREGRLD
ALLEERDIVGSSR

Sequences:

>Translated_93_residues
MADVTIYTRMGCGYCVAAKRLLERKGIAYTEQDASFSPELRKEMIGRANGRSTFPQIFIGNIHVGGSDDLHALEREGRLD
ALLEERDIVGSSR
>Mature_92_residues
ADVTIYTRMGCGYCVAAKRLLERKGIAYTEQDASFSPELRKEMIGRANGRSTFPQIFIGNIHVGGSDDLHALEREGRLDA
LLEERDIVGSSR

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=84, Percent_Identity=50, Blast_Score=80, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10332; Mature: 10201

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVTIYTRMGCGYCVAAKRLLERKGIAYTEQDASFSPELRKEMIGRANGRSTFPQIFIG
CCCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHCCCCCCCCCCEEEEE
NIHVGGSDDLHALEREGRLDALLEERDIVGSSR
EEEECCCCCHHHHHHCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADVTIYTRMGCGYCVAAKRLLERKGIAYTEQDASFSPELRKEMIGRANGRSTFPQIFIG
CCEEEEECCCCCHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHCCCCCCCCCCEEEEE
NIHVGGSDDLHALEREGRLDALLEERDIVGSSR
EEEECCCCCHHHHHHCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]