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The map label for this gene is yafV [C]

Identifier: 110635333

GI number: 110635333

Start: 3272984

End: 3273835

Strand: Reverse

Name: yafV [C]

Synonym: Meso_3004

Alternate gene names: 110635333

Gene position: 3273835-3272984 (Counterclockwise)

Preceding gene: 110635334

Following gene: 110635332

Centisome position: 74.2

GC content: 64.08

Gene sequence:

>852_bases
ATGACGGCCGTCCGCGTCGCTGCGCTGCAGATGCGCTCCGGCACGGAGCCGGAGGCAAATCTTTCCGCTTTTGAAGCGCT
TGTGCGTGAAGCGGCGGCCCGAGGCGCAAAATATGTGCAAAGCCCGGAGATGACGGGCGCGCTTGTGCGCTCTCGCGAGG
CGCTTATGGCGCGGATTAAGCCGGCGGATGAAAACCCGCTCGTGCGGCGTGCCGCGGAGTTGGCGCGCGAACTTTCGATA
TATGTGCATCTCGGTTCGACGGCGATTCCCCTCGATGGCGGCAAGGTTGCGAACAGGGCCTTTCTGTTCGGCCCCGACGG
AACGTTGATCGCCACCTATGACAAGATCCACATGTTCGATGTCGATCTCGACAAGGGGGAAAGCTGGCGCGAATCGGCGA
CCTACGCGCCGGGCGCACGGACCGTCGTGGCGGCGCTTCCCTTCGCCCGCATCGGACTTGCCGTTTGTTACGATCTGCGG
TTTCCCCAGCTTTTCCGCGCGCAGGCGCTGGCAGGCGCCGAGGTGCTGACCGTGCCTGCCGCCTTTACCCGGCAGACCGG
CGAGGCGCACTGGCATGTTCTGACGCGTGCGCGGGCCATCGAAAACGGTGCCTGGGTCATCGCGGCGGCACAGGGCGGGT
TGCATGAGGACCGCCGCGAGACCTTCGGTCACTCGCTGATCGTCGATCCTTGGGGGCGGATCGTCGCCGAGGCAAATCAT
GATGAACCGGCGGTGGTGCTGGCTGAGATCGATCCGGCGGCTTCGGCGGAGGCGCGGCAGAAAATCCCGAATCTCAAGAA
CGCTCGCGAATTCAGGATAGAAGAAGCTTCTTACCGCGAGGTGACAGCGTGA

Upstream 100 bases:

>100_bases
GGAATATTCATGTAGGCGGTTCTGACGATCTGCACGCGCTGGAGCGGGAAGGCAGGCTTGACGCCCTTCTGGAGGAACGG
GACATCGTGGGGAGCAGTCG

Downstream 100 bases:

>100_bases
TCCGCTACGGCCTCATTTGCGACAAGGAACATGAGTTCGAGGCGTGGTTCCGCAGTGGCGAGGATTTCGAGACGCAGAAG
AGCCGCAAGCTTGTCTCCTG

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTAVRVAALQMRSGTEPEANLSAFEALVREAAARGAKYVQSPEMTGALVRSREALMARIKPADENPLVRRAAELARELSI
YVHLGSTAIPLDGGKVANRAFLFGPDGTLIATYDKIHMFDVDLDKGESWRESATYAPGARTVVAALPFARIGLAVCYDLR
FPQLFRAQALAGAEVLTVPAAFTRQTGEAHWHVLTRARAIENGAWVIAAAQGGLHEDRRETFGHSLIVDPWGRIVAEANH
DEPAVVLAEIDPAASAEARQKIPNLKNAREFRIEEASYREVTA

Sequences:

>Translated_283_residues
MTAVRVAALQMRSGTEPEANLSAFEALVREAAARGAKYVQSPEMTGALVRSREALMARIKPADENPLVRRAAELARELSI
YVHLGSTAIPLDGGKVANRAFLFGPDGTLIATYDKIHMFDVDLDKGESWRESATYAPGARTVVAALPFARIGLAVCYDLR
FPQLFRAQALAGAEVLTVPAAFTRQTGEAHWHVLTRARAIENGAWVIAAAQGGLHEDRRETFGHSLIVDPWGRIVAEANH
DEPAVVLAEIDPAASAEARQKIPNLKNAREFRIEEASYREVTA
>Mature_282_residues
TAVRVAALQMRSGTEPEANLSAFEALVREAAARGAKYVQSPEMTGALVRSREALMARIKPADENPLVRRAAELARELSIY
VHLGSTAIPLDGGKVANRAFLFGPDGTLIATYDKIHMFDVDLDKGESWRESATYAPGARTVVAALPFARIGLAVCYDLRF
PQLFRAQALAGAEVLTVPAAFTRQTGEAHWHVLTRARAIENGAWVIAAAQGGLHEDRRETFGHSLIVDPWGRIVAEANHD
EPAVVLAEIDPAASAEARQKIPNLKNAREFRIEEASYREVTA

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=37.4074074074074, Blast_Score=184, Evalue=7e-47,
Organism=Homo sapiens, GI297632348, Length=272, Percent_Identity=37.8676470588235, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI5031947, Length=272, Percent_Identity=37.8676470588235, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI297632350, Length=272, Percent_Identity=37.8676470588235, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI297632346, Length=194, Percent_Identity=35.5670103092784, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI1786412, Length=189, Percent_Identity=33.8624338624339, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17556280, Length=267, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322335, Length=296, Percent_Identity=33.445945945946, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323383, Length=288, Percent_Identity=32.9861111111111, Blast_Score=156, Evalue=3e-39,
Organism=Drosophila melanogaster, GI17933642, Length=270, Percent_Identity=37.7777777777778, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI21355835, Length=264, Percent_Identity=28.4090909090909, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30791; Mature: 30660

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVRVAALQMRSGTEPEANLSAFEALVREAAARGAKYVQSPEMTGALVRSREALMARIK
CCCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCC
PADENPLVRRAAELARELSIYVHLGSTAIPLDGGKVANRAFLFGPDGTLIATYDKIHMFD
CCCCCHHHHHHHHHHHHEEEEEEECCEEEECCCCCCCCEEEEECCCCCEEEEECEEEEEE
VDLDKGESWRESATYAPGARTVVAALPFARIGLAVCYDLRFPQLFRAQALAGAEVLTVPA
EECCCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECH
AFTRQTGEAHWHVLTRARAIENGAWVIAAAQGGLHEDRRETFGHSLIVDPWGRIVAEANH
HHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCEEEECCHHHHEECCCC
DEPAVVLAEIDPAASAEARQKIPNLKNAREFRIEEASYREVTA
CCCEEEEEECCCCCCHHHHHHCCCCCCCHHHEECCCCCCCCCC
>Mature Secondary Structure 
TAVRVAALQMRSGTEPEANLSAFEALVREAAARGAKYVQSPEMTGALVRSREALMARIK
CCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHCC
PADENPLVRRAAELARELSIYVHLGSTAIPLDGGKVANRAFLFGPDGTLIATYDKIHMFD
CCCCCHHHHHHHHHHHHEEEEEEECCEEEECCCCCCCCEEEEECCCCCEEEEECEEEEEE
VDLDKGESWRESATYAPGARTVVAALPFARIGLAVCYDLRFPQLFRAQALAGAEVLTVPA
EECCCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECH
AFTRQTGEAHWHVLTRARAIENGAWVIAAAQGGLHEDRRETFGHSLIVDPWGRIVAEANH
HHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCCCEEEECCHHHHEECCCC
DEPAVVLAEIDPAASAEARQKIPNLKNAREFRIEEASYREVTA
CCCEEEEEECCCCCCHHHHHHCCCCCCCHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]