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The map label for this gene is siaT [H]

Identifier: 110635232

GI number: 110635232

Start: 3153601

End: 3154863

Strand: Reverse

Name: siaT [H]

Synonym: Meso_2902

Alternate gene names: 110635232

Gene position: 3154863-3153601 (Counterclockwise)

Preceding gene: 110635233

Following gene: 110635231

Centisome position: 71.5

GC content: 55.82

Gene sequence:

>1263_bases
TTGGTCTACGCTGGCTTGCATGTGCCTGTAGCCTTTATTCTGGTTTCCTTTTTCGGCGTTTTTCTCGTTCGCGGCAGTTT
CGACGTTGCCGCTAACTCGCTGGTGATCGCCGCGACGGATTCAATATCGAGCTACACCTTTGCAACGGTCCCGGTCTTCG
TGTTCATGGGATTGCTGGTTGTTCTCGCCGGAATGGGACGCTCTACATTTGATGTCGCCGCCCATGCCACTAGGCGTCTT
CCGGGCGGCCTCGCCATCGGTTCAGTCGGTGCGAACGCGATTTTTGCGGCTACCATCGGTGTGGGTATCGCGGCGGCTGC
AATCTTTTCCAAACTCGCGATTCCGGAGATGCAGCGATACGGCTATTCGCTCCGGCGATCTGCAGGCGTGGTCGCAGCGG
CATCCCTTCTGGGCCCGCTCATTCCGCCCAGTCTGTTACTGATCCTTTTCGGCGTGATGACGTTCACCTCGATAGGGTCA
CTCTTTCTCGCCGCAGTAATTCCAGGGTTGTTGCTTGCTGCCGCCTATGTGCTGTTCATTGTGCTAGAGGCGCGCTTCCG
GCCGGCCATCTATGGGGGCACGGATGCGGATCGTCCCTGCGGGCCTGCCATGACCTGGCGCGAGATCATCCTCAAGATCG
GACCCATCACTGTCCTCGTATTTCTAATCTTCGGTGGCCTTTATGGTGGCATTTTCACAGCGAACGAGGCCGGCGCGATG
GGTGCATTCGGCGCACTTCTGTTCGCGCTTTTCAAGGTTAGAAACCCGAAAACCTACTGGCGTCTGCTGACCGAAACCGG
CCAGGTCACCGCATCTATTCTGCTGCTGGTGATTGGTGCCAGTATTTATACCCGTATGCTGGCTCTCACGGGCGTTCCTG
CAGCTCTTGTAGGTCTCTTCTCCGACCTCGGCCTGGGTGTCGTCGGAACGCTGGTCATCTACGTGACCATAATCCTTCTG
CTCGGTACTCTTATTGACTCCGCGTCCATCATTCTTCTCGTGGTTCCGCTGATGTATCCTATCTTTCAGTCCATGAACGT
GGACCCGATCTGGCTGGGAATAATAACCGTCATGAGCGTCGAAGTCGGTCTTCTGACACCACCTTTCGGCATGGCCGCCT
TCGTCGTTAAAGCCACTTCGGAGCAGAAAGAACTGAAGGTCGAGGACGTATATTGGGGAGCCGCACCATTTGCGATCATC
ACGATTGGCGTGGTCGGTCTTTTGATCCTGTTTCCTCAGCTAACGACTGTTCTGTTAAGGTAG

Upstream 100 bases:

>100_bases
AGTTCCTCTTTTCGTTGCTTGAGAATGCACGCGCAGTGCGGCGGGGAAAGTCGTAAGCGGTTTTGAAATAGGTCTATCCT
CTGTTGGGTTATTGATATTA

Downstream 100 bases:

>100_bases
CAAAGGGAAAGAAGCATTCGAATTGGGTTCTCTACTTGATCGCTCCGGACGGCAAGCCACCAGCCCTCGCTAGCGGGGGT
GACGGCCGAAGTCCCGGCAT

Product: TRAP C4-dicarboxylate transport system permease DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MVYAGLHVPVAFILVSFFGVFLVRGSFDVAANSLVIAATDSISSYTFATVPVFVFMGLLVVLAGMGRSTFDVAAHATRRL
PGGLAIGSVGANAIFAATIGVGIAAAAIFSKLAIPEMQRYGYSLRRSAGVVAAASLLGPLIPPSLLLILFGVMTFTSIGS
LFLAAVIPGLLLAAAYVLFIVLEARFRPAIYGGTDADRPCGPAMTWREIILKIGPITVLVFLIFGGLYGGIFTANEAGAM
GAFGALLFALFKVRNPKTYWRLLTETGQVTASILLLVIGASIYTRMLALTGVPAALVGLFSDLGLGVVGTLVIYVTIILL
LGTLIDSASIILLVVPLMYPIFQSMNVDPIWLGIITVMSVEVGLLTPPFGMAAFVVKATSEQKELKVEDVYWGAAPFAII
TIGVVGLLILFPQLTTVLLR

Sequences:

>Translated_420_residues
MVYAGLHVPVAFILVSFFGVFLVRGSFDVAANSLVIAATDSISSYTFATVPVFVFMGLLVVLAGMGRSTFDVAAHATRRL
PGGLAIGSVGANAIFAATIGVGIAAAAIFSKLAIPEMQRYGYSLRRSAGVVAAASLLGPLIPPSLLLILFGVMTFTSIGS
LFLAAVIPGLLLAAAYVLFIVLEARFRPAIYGGTDADRPCGPAMTWREIILKIGPITVLVFLIFGGLYGGIFTANEAGAM
GAFGALLFALFKVRNPKTYWRLLTETGQVTASILLLVIGASIYTRMLALTGVPAALVGLFSDLGLGVVGTLVIYVTIILL
LGTLIDSASIILLVVPLMYPIFQSMNVDPIWLGIITVMSVEVGLLTPPFGMAAFVVKATSEQKELKVEDVYWGAAPFAII
TIGVVGLLILFPQLTTVLLR
>Mature_420_residues
MVYAGLHVPVAFILVSFFGVFLVRGSFDVAANSLVIAATDSISSYTFATVPVFVFMGLLVVLAGMGRSTFDVAAHATRRL
PGGLAIGSVGANAIFAATIGVGIAAAAIFSKLAIPEMQRYGYSLRRSAGVVAAASLLGPLIPPSLLLILFGVMTFTSIGS
LFLAAVIPGLLLAAAYVLFIVLEARFRPAIYGGTDADRPCGPAMTWREIILKIGPITVLVFLIFGGLYGGIFTANEAGAM
GAFGALLFALFKVRNPKTYWRLLTETGQVTASILLLVIGASIYTRMLALTGVPAALVGLFSDLGLGVVGTLVIYVTIILL
LGTLIDSASIILLVVPLMYPIFQSMNVDPIWLGIITVMSVEVGLLTPPFGMAAFVVKATSEQKELKVEDVYWGAAPFAII
TIGVVGLLILFPQLTTVLLR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=401, Percent_Identity=27.431421446384, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44128; Mature: 44128

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYAGLHVPVAFILVSFFGVFLVRGSFDVAANSLVIAATDSISSYTFATVPVFVFMGLLV
CEECCHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHH
VLAGMGRSTFDVAAHATRRLPGGLAIGSVGANAIFAATIGVGIAAAAIFSKLAIPEMQRY
HHHCCCCCHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GYSLRRSAGVVAAASLLGPLIPPSLLLILFGVMTFTSIGSLFLAAVIPGLLLAAAYVLFI
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLEARFRPAIYGGTDADRPCGPAMTWREIILKIGPITVLVFLIFGGLYGGIFTANEAGAM
HHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCH
GAFGALLFALFKVRNPKTYWRLLTETGQVTASILLLVIGASIYTRMLALTGVPAALVGLF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SDLGLGVVGTLVIYVTIILLLGTLIDSASIILLVVPLMYPIFQSMNVDPIWLGIITVMSV
HHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EVGLLTPPFGMAAFVVKATSEQKELKVEDVYWGAAPFAIITIGVVGLLILFPQLTTVLLR
HHHCCCCCCHHHHHHHHCCCCHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVYAGLHVPVAFILVSFFGVFLVRGSFDVAANSLVIAATDSISSYTFATVPVFVFMGLLV
CEECCHHHHHHHHHHHHHHHHHHCCCHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHH
VLAGMGRSTFDVAAHATRRLPGGLAIGSVGANAIFAATIGVGIAAAAIFSKLAIPEMQRY
HHHCCCCCHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GYSLRRSAGVVAAASLLGPLIPPSLLLILFGVMTFTSIGSLFLAAVIPGLLLAAAYVLFI
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLEARFRPAIYGGTDADRPCGPAMTWREIILKIGPITVLVFLIFGGLYGGIFTANEAGAM
HHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCH
GAFGALLFALFKVRNPKTYWRLLTETGQVTASILLLVIGASIYTRMLALTGVPAALVGLF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SDLGLGVVGTLVIYVTIILLLGTLIDSASIILLVVPLMYPIFQSMNVDPIWLGIITVMSV
HHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EVGLLTPPFGMAAFVVKATSEQKELKVEDVYWGAAPFAIITIGVVGLLILFPQLTTVLLR
HHHCCCCCCHHHHHHHHCCCCHHHCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]