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The map label for this gene is ycgM [C]

Identifier: 110635231

GI number: 110635231

Start: 3152562

End: 3153425

Strand: Reverse

Name: ycgM [C]

Synonym: Meso_2901

Alternate gene names: 110635231

Gene position: 3153425-3152562 (Counterclockwise)

Preceding gene: 110635232

Following gene: 110635230

Centisome position: 71.47

GC content: 57.06

Gene sequence:

>864_bases
ATGAAGTTGGCTTTGTTCACCCACGGCGGTGTAAGGCGTATCGGGCTGGTCGAGCGCGGGGAAGTTGTCGACCTGCTAAG
CGGCAATCCGCGTCTGCCGAACGATATGGTGGCCATTCTGGAAGGTGGGGCTGAAACTCTGGAAGCAGTCCGCTTGGCCG
CAGGTCGCGCCAATCGGCTTGCCCTTAACGAGGTTCAACTGAATGCGCCGATTACAAGGCCGCGAAAATTCCTCGGGCTT
GGCCTGAGTTTCAAATCCAGCGCCGATGAGTTCCGCGCGAAGGGTGTTGCTATCCCCGAACATCAGGTCTGGTTTAACAA
GCAGGTCACCGCGATTAATGGCCCCTATGACCCCGTCCATATGCCGCGCGTCTCATCGGAACTCGATTATGAGGGAGAAT
TGGCTCTCGTGATCGGCAAGCGGATACGTCATGCGAGGACGTCAGACGCGGAAAAAATTATTGCCGGGTTCTTGGTCTGC
AATGATTTCAGTGTTCGCGACTGGCAACGCCGCTCACCCACGGCCACGCTGGGCAAATCTTTTGACACGCACGGTCCGAT
CGGCCCGTGGCTGACAACCTTCGACGAAGTCGATCCGAGCAGCCTGCGGATACGGACCTGGGTGGATGGCGAGCTGCGGC
AAGACGGCAATACCGATGACCTGCTCTATACGTTTGGTGAAATGATCGCGGAACTCTCCACTGCTTTCACGCTCGAACCG
GGTGACATACTGGCGACCGGCAGTCCTACAGGTGCCGGGCAATATATGCGTCCACCGACTTATCTGAAGACCGGGCAAAC
AGTACGAGTGGAAATCGAGGGGCTTGGGCACATCGAAAATATGATCGTGGATGAGCCAGGCTGA

Upstream 100 bases:

>100_bases
GGGGTGACGGCCGAAGTCCCGGCATCTTGAACCTCCGGCACAGGTGGTGGATTCCAACCGCGGCGTACAAGCAGCAAAGC
GCGATAACTAGGAGCGACTG

Downstream 100 bases:

>100_bases
TGTAGACTCAGGCAAAGCCGGTAACCACTCTTAATCCAGTTTTGAATGTGTCCTGGAAAGGGGTGGCGATCAGCTATCTT
GTCGGTTTCCGCAGCCGCCA

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKLALFTHGGVRRIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVRLAAGRANRLALNEVQLNAPITRPRKFLGL
GLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVHMPRVSSELDYEGELALVIGKRIRHARTSDAEKIIAGFLVC
NDFSVRDWQRRSPTATLGKSFDTHGPIGPWLTTFDEVDPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEP
GDILATGSPTGAGQYMRPPTYLKTGQTVRVEIEGLGHIENMIVDEPG

Sequences:

>Translated_287_residues
MKLALFTHGGVRRIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVRLAAGRANRLALNEVQLNAPITRPRKFLGL
GLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVHMPRVSSELDYEGELALVIGKRIRHARTSDAEKIIAGFLVC
NDFSVRDWQRRSPTATLGKSFDTHGPIGPWLTTFDEVDPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEP
GDILATGSPTGAGQYMRPPTYLKTGQTVRVEIEGLGHIENMIVDEPG
>Mature_287_residues
MKLALFTHGGVRRIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVRLAAGRANRLALNEVQLNAPITRPRKFLGL
GLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVHMPRVSSELDYEGELALVIGKRIRHARTSDAEKIIAGFLVC
NDFSVRDWQRRSPTATLGKSFDTHGPIGPWLTTFDEVDPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEP
GDILATGSPTGAGQYMRPPTYLKTGQTVRVEIEGLGHIENMIVDEPG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=268, Percent_Identity=41.7910447761194, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI40786394, Length=268, Percent_Identity=40.6716417910448, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI215422413, Length=173, Percent_Identity=33.5260115606936, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI13654274, Length=173, Percent_Identity=33.5260115606936, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66348062, Length=173, Percent_Identity=33.5260115606936, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1787428, Length=213, Percent_Identity=30.5164319248826, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17557057, Length=181, Percent_Identity=31.4917127071823, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324161, Length=177, Percent_Identity=29.9435028248588, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28572127, Length=277, Percent_Identity=36.8231046931408, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24663695, Length=279, Percent_Identity=30.8243727598566, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571789, Length=185, Percent_Identity=30.2702702702703, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 31505; Mature: 31505

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLALFTHGGVRRIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVRLAAGRANRL
CEEEEEECCCCEEECEECCCCEEEECCCCCCCCHHHHHEECCCHHHHHHHHHHCCCCCCE
ALNEVQLNAPITRPRKFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVH
EEEEEEECCCCCCCHHHHEECCCCCCCHHHHHHCCCCCCCCCEEECCEEEEECCCCCCCC
MPRVSSELDYEGELALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTATLGKS
CCCCCCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHEECCCCCCCHHHCCCCHHHCCC
FDTHGPIGPWLTTFDEVDPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEP
CCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEECC
GDILATGSPTGAGQYMRPPTYLKTGQTVRVEIEGLGHIENMIVDEPG
CCEEEECCCCCCCCCCCCCCEEECCCEEEEEECCCCCCHHEEECCCC
>Mature Secondary Structure
MKLALFTHGGVRRIGLVERGEVVDLLSGNPRLPNDMVAILEGGAETLEAVRLAAGRANRL
CEEEEEECCCCEEECEECCCCEEEECCCCCCCCHHHHHEECCCHHHHHHHHHHCCCCCCE
ALNEVQLNAPITRPRKFLGLGLSFKSSADEFRAKGVAIPEHQVWFNKQVTAINGPYDPVH
EEEEEEECCCCCCCHHHHEECCCCCCCHHHHHHCCCCCCCCCEEECCEEEEECCCCCCCC
MPRVSSELDYEGELALVIGKRIRHARTSDAEKIIAGFLVCNDFSVRDWQRRSPTATLGKS
CCCCCCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHHHHEECCCCCCCHHHCCCCHHHCCC
FDTHGPIGPWLTTFDEVDPSSLRIRTWVDGELRQDGNTDDLLYTFGEMIAELSTAFTLEP
CCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEECC
GDILATGSPTGAGQYMRPPTYLKTGQTVRVEIEGLGHIENMIVDEPG
CCEEEECCCCCCCCCCCCCCEEECCCEEEEEECCCCCCHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA