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The map label for this gene is exaA [H]

Identifier: 110635223

GI number: 110635223

Start: 3143770

End: 3145521

Strand: Reverse

Name: exaA [H]

Synonym: Meso_2890

Alternate gene names: 110635223

Gene position: 3145521-3143770 (Counterclockwise)

Preceding gene: 110635224

Following gene: 110635222

Centisome position: 71.29

GC content: 60.96

Gene sequence:

>1752_bases
GTGAAAACTCTTATAAAGTCGCTCCTGATGGCGACAGCCGCGTTCGCGGTGATCTCAGCGCCCGCCCTTGCCCAGAACAC
GCGTGAATATTCGCCCGTCACGGACGAGATGCTCGCCAATCCGCCGGCAGAAGACTGGCTTTCCTTCCGTGGCGCCTACA
ACAACCAGGGTTACAGCAAGCTCGACCTCATCAACAAGGATACGGTTGACGATCTGGAGCTGGCATGGGCTTGGCCCATG
GCCGAGGCGGGCATTCAGGAAACGGCTCCCCTCATCCATGACGGCATCCTTTTCCTGCAGACCAACAACAATATCGTCGA
GGCGCTCGACGCCAAGACCGGCGACCGCATCTGGACCTATATCCATGAGTTGCCTGAACTGCCGGCAAGCTGGAGTTACC
AGCTCAACCAGGCACGCCGTCAGAAGGCGTCCATCGCGCTCTATCAGGACAAGGTGGTCCTGACCACCGTCGATGCCAAG
ATCGTCGTGCTCAACGCACTCGACGGCAAGGTCGTCTGGGAAAAGCAGGTTCTCGACTACAACAAGGGCTACAGCTACAC
GGTCGGCCCGATCGTCGTTGACAATAAAATCATCAGCGCCATTTCGGGCTGCTCCATCGCCGGCACCGCGGGCGGCTGCT
ATATCCTGGCCCATGATTTCGAGACGGGCGAGGAGCTCTGGCGCTTCAACACGATCAATGACCCCGACAATCCTGAACAG
CAGGCGAGCTGGGGTGAGGTTCCGCCGGAAAACCGCTGGGGCGGCACGCCCTGGACCATCGGCTCCTATGATCCCGAGAC
CCGCACTACCTTCTGGGGCATCGGAATGCCCGGTCCCTATTCCGAGCTGATTCGCGGCTCGGGCGACGGGTCGGTGCTCT
ACACCAACTCAACGATCGCGCTCGACATCGATACCGGTAAGCTCAAGTGGTACTACCAGCACCTGCCGCGCGACAACTGG
GATCTCGACAGCCCGTTCGAACGCATCCTCGTCGACCAGGAAGTCGATGGCGAAGTCAAGAAGATGCTCGTGACCGTCGC
AGGCAAGAACGGCATCGCCTTCGGGCTTGACCGGGAGACCGGCAAGTATCTCTGGCACAAGGAGACGGTCCATCAGAACG
TGGTCACCGGGATCGATCCGGATGGCACCGTGCATATCAATGAGGACCTGGTTGCGAAGGCAGTCGGCGAGGAGCATCTT
GTCTGCGCCTCGGTATCGGGTGGTAAGCTGTGGCAGGCAGGTTCCTATAGTCCGCTGACCCAAGCTTATTATGTGCCCTT
GACGGAAGCCTGCAATACCGTGGCTCCGACCCAGACCGAGTTCACTGCCGGCAACGCGGTGGGCGCGATGAAGTTTGGTC
CGCGTGTCCTGCCCGAAGGCGTCACCGAGGCCGGCCTTGTTCAGGCAATCGCGGTCACTCCGACGTCCGGCAAGACCAAG
TGGGACTACCGTTCGCGCCCGACCCCGACCAGCTCCGTGCTGGCGACGGCCGGTGGTCTTGTCTTCGGTGGTGACGCAGC
GCGCGATGTGAAGGCCTGGGACCAGGAAACGGGCGAGGTGGTCTGGTCGCAGCGCCTCAATGCTCCGATCGGCGGCTATC
CTGCCACCTATGCAGTCGATGGCGAGCAGTACCTGGTGGTGCCCACCGGCTACTCGAACTCCGCCAGCTCGATTTCTTCG
GCATTCCCGGAGATTCCGCTGCCGACAGGCTCGGGCAACTCCATCTTCGTGTTCAAGCTGCCCAGCAAGTAA

Upstream 100 bases:

>100_bases
CGGCCGTTCCACAGGCATACACTTGGGGCAAGCAATTGCCGCAAGCCAGCCCGCAATAAGCTTCATCCGCCGACAAGCAC
TGTTCACTTCGGAGGTATCC

Downstream 100 bases:

>100_bases
ATCGGAATAGACGCGAGAAAGGGGCCGCAAGGCCCCTTTCGACTTTAGGTAATATGATGCGACAGTTCCTCTCAGCGGTT
TTTCTTCTCGTCGCGTGCGC

Product: Pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKTLIKSLLMATAAFAVISAPALAQNTREYSPVTDEMLANPPAEDWLSFRGAYNNQGYSKLDLINKDTVDDLELAWAWPM
AEAGIQETAPLIHDGILFLQTNNNIVEALDAKTGDRIWTYIHELPELPASWSYQLNQARRQKASIALYQDKVVLTTVDAK
IVVLNALDGKVVWEKQVLDYNKGYSYTVGPIVVDNKIISAISGCSIAGTAGGCYILAHDFETGEELWRFNTINDPDNPEQ
QASWGEVPPENRWGGTPWTIGSYDPETRTTFWGIGMPGPYSELIRGSGDGSVLYTNSTIALDIDTGKLKWYYQHLPRDNW
DLDSPFERILVDQEVDGEVKKMLVTVAGKNGIAFGLDRETGKYLWHKETVHQNVVTGIDPDGTVHINEDLVAKAVGEEHL
VCASVSGGKLWQAGSYSPLTQAYYVPLTEACNTVAPTQTEFTAGNAVGAMKFGPRVLPEGVTEAGLVQAIAVTPTSGKTK
WDYRSRPTPTSSVLATAGGLVFGGDAARDVKAWDQETGEVVWSQRLNAPIGGYPATYAVDGEQYLVVPTGYSNSASSISS
AFPEIPLPTGSGNSIFVFKLPSK

Sequences:

>Translated_583_residues
MKTLIKSLLMATAAFAVISAPALAQNTREYSPVTDEMLANPPAEDWLSFRGAYNNQGYSKLDLINKDTVDDLELAWAWPM
AEAGIQETAPLIHDGILFLQTNNNIVEALDAKTGDRIWTYIHELPELPASWSYQLNQARRQKASIALYQDKVVLTTVDAK
IVVLNALDGKVVWEKQVLDYNKGYSYTVGPIVVDNKIISAISGCSIAGTAGGCYILAHDFETGEELWRFNTINDPDNPEQ
QASWGEVPPENRWGGTPWTIGSYDPETRTTFWGIGMPGPYSELIRGSGDGSVLYTNSTIALDIDTGKLKWYYQHLPRDNW
DLDSPFERILVDQEVDGEVKKMLVTVAGKNGIAFGLDRETGKYLWHKETVHQNVVTGIDPDGTVHINEDLVAKAVGEEHL
VCASVSGGKLWQAGSYSPLTQAYYVPLTEACNTVAPTQTEFTAGNAVGAMKFGPRVLPEGVTEAGLVQAIAVTPTSGKTK
WDYRSRPTPTSSVLATAGGLVFGGDAARDVKAWDQETGEVVWSQRLNAPIGGYPATYAVDGEQYLVVPTGYSNSASSISS
AFPEIPLPTGSGNSIFVFKLPSK
>Mature_583_residues
MKTLIKSLLMATAAFAVISAPALAQNTREYSPVTDEMLANPPAEDWLSFRGAYNNQGYSKLDLINKDTVDDLELAWAWPM
AEAGIQETAPLIHDGILFLQTNNNIVEALDAKTGDRIWTYIHELPELPASWSYQLNQARRQKASIALYQDKVVLTTVDAK
IVVLNALDGKVVWEKQVLDYNKGYSYTVGPIVVDNKIISAISGCSIAGTAGGCYILAHDFETGEELWRFNTINDPDNPEQ
QASWGEVPPENRWGGTPWTIGSYDPETRTTFWGIGMPGPYSELIRGSGDGSVLYTNSTIALDIDTGKLKWYYQHLPRDNW
DLDSPFERILVDQEVDGEVKKMLVTVAGKNGIAFGLDRETGKYLWHKETVHQNVVTGIDPDGTVHINEDLVAKAVGEEHL
VCASVSGGKLWQAGSYSPLTQAYYVPLTEACNTVAPTQTEFTAGNAVGAMKFGPRVLPEGVTEAGLVQAIAVTPTSGKTK
WDYRSRPTPTSSVLATAGGLVFGGDAARDVKAWDQETGEVVWSQRLNAPIGGYPATYAVDGEQYLVVPTGYSNSASSISS
AFPEIPLPTGSGNSIFVFKLPSK

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=370, Percent_Identity=27.8378378378378, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 63442; Mature: 63442

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLIKSLLMATAAFAVISAPALAQNTREYSPVTDEMLANPPAEDWLSFRGAYNNQGYSK
CHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCCCE
LDLINKDTVDDLELAWAWPMAEAGIQETAPLIHDGILFLQTNNNIVEALDAKTGDRIWTY
EEECCCCCCCCCEEEEECCHHHCCHHHCCCHHHCCEEEEEECCCEEEECCCCCCCHHHHH
IHELPELPASWSYQLNQARRQKASIALYQDKVVLTTVDAKIVVLNALDGKVVWEKQVLDY
HHHHHCCCCCCCHHHHHHHHHHCEEEEEECEEEEEEECEEEEEEEECCCCEEEEHHHHCC
NKGYSYTVGPIVVDNKIISAISGCSIAGTAGGCYILAHDFETGEELWRFNTINDPDNPEQ
CCCCCEEECCEEECCHHHHHHCCCEEEECCCCEEEEEECCCCCHHHHEECCCCCCCCCHH
QASWGEVPPENRWGGTPWTIGSYDPETRTTFWGIGMPGPYSELIRGSGDGSVLYTNSTIA
HCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCEEEECCEEE
LDIDTGKLKWYYQHLPRDNWDLDSPFERILVDQEVDGEVKKMLVTVAGKNGIAFGLDRET
EEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCHHEEEEEEEECCCCEEEECCCCC
GKYLWHKETVHQNVVTGIDPDGTVHINEDLVAKAVGEEHLVCASVSGGKLWQAGSYSPLT
CCEEEEHHHHHHHHHCCCCCCCEEEECHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCC
QAYYVPLTEACNTVAPTQTEFTAGNAVGAMKFGPRVLPEGVTEAGLVQAIAVTPTSGKTK
EEEEEEHHHHCCCCCCCCCEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
WDYRSRPTPTSSVLATAGGLVFGGDAARDVKAWDQETGEVVWSQRLNAPIGGYPATYAVD
CCCCCCCCCHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
GEQYLVVPTGYSNSASSISSAFPEIPLPTGSGNSIFVFKLPSK
CCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKTLIKSLLMATAAFAVISAPALAQNTREYSPVTDEMLANPPAEDWLSFRGAYNNQGYSK
CHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCCCE
LDLINKDTVDDLELAWAWPMAEAGIQETAPLIHDGILFLQTNNNIVEALDAKTGDRIWTY
EEECCCCCCCCCEEEEECCHHHCCHHHCCCHHHCCEEEEEECCCEEEECCCCCCCHHHHH
IHELPELPASWSYQLNQARRQKASIALYQDKVVLTTVDAKIVVLNALDGKVVWEKQVLDY
HHHHHCCCCCCCHHHHHHHHHHCEEEEEECEEEEEEECEEEEEEEECCCCEEEEHHHHCC
NKGYSYTVGPIVVDNKIISAISGCSIAGTAGGCYILAHDFETGEELWRFNTINDPDNPEQ
CCCCCEEECCEEECCHHHHHHCCCEEEECCCCEEEEEECCCCCHHHHEECCCCCCCCCHH
QASWGEVPPENRWGGTPWTIGSYDPETRTTFWGIGMPGPYSELIRGSGDGSVLYTNSTIA
HCCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCEEEECCEEE
LDIDTGKLKWYYQHLPRDNWDLDSPFERILVDQEVDGEVKKMLVTVAGKNGIAFGLDRET
EEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCHHEEEEEEEECCCCEEEECCCCC
GKYLWHKETVHQNVVTGIDPDGTVHINEDLVAKAVGEEHLVCASVSGGKLWQAGSYSPLT
CCEEEEHHHHHHHHHCCCCCCCEEEECHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCC
QAYYVPLTEACNTVAPTQTEFTAGNAVGAMKFGPRVLPEGVTEAGLVQAIAVTPTSGKTK
EEEEEEHHHHCCCCCCCCCEECCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
WDYRSRPTPTSSVLATAGGLVFGGDAARDVKAWDQETGEVVWSQRLNAPIGGYPATYAVD
CCCCCCCCCHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
GEQYLVVPTGYSNSASSISSAFPEIPLPTGSGNSIFVFKLPSK
CCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]