Click here to switch to the map view.

The map label for this gene is murQ [H]

Identifier: 110635198

GI number: 110635198

Start: 3116387

End: 3117280

Strand: Reverse

Name: murQ [H]

Synonym: Meso_2865

Alternate gene names: 110635198

Gene position: 3117280-3116387 (Counterclockwise)

Preceding gene: 110635203

Following gene: 110635197

Centisome position: 70.65

GC content: 62.98

Gene sequence:

>894_bases
ATGGTGAGCCTGCACACGGAAAGCACGGGTGACAGATACCGAGATCTTGAGCTTGCGCCGGACGGCGAGCTGCTGCGCAT
GATGCTGGATGGGCAGAAAAATGCCTTCTCCGCCGTATCCGACGCTCTTCCCGCGTTGGAGAGCGCACTTGCAGCGATGG
TGAAGCGGCTTCGTGGATCCGCGGGGCGATTGTTCTATGTGGGCGCTGGCACCTCGGGCAGGCTGGCGGTGCTTGATGCG
CTGGAACTTGGGCCTACATTCAGTTGGCCGGATGAGCGCCTGGTGTTGTTGCTTGCGGGCGGTCTTGGCCTTGCGGGTGT
GGCCGAGGCGGCCGAAGACGACATACACGCGGCGGTGCGCGCCATAGAGAATGCCGGCTGCGGGCATGACGATGTTATTC
TCGCGCTCGCGGCGAGCGGGACGACACCGTACACATTGGCGGCCGTTGAAGCGGCGCGCAAATGCGGCGCGCTTACCATA
GGGCTTGCCAATAATCCCGGCGCGCCGCTGCTTGGGAGAGCGGAGATTGGCATTCTGCTCGACACCGGCCCGGAGGCGGT
TGCGGGCTCCACGCGCCTTGCCGCGGGAACGAGCCAGAAGATAGCCCTCAACCTGCTTTCCACGGCTCTTATGGCGCGGC
TCGGTAAAGTCTTCCGCGGCCAGATGGTGGATATGAAGGCAGCAAACGACAAGCTCCATCGCAGGGCCGCGACCATACTT
GTCGAGATTTCGGGATGCAGCAGAGAAGAGGCTGTCGCGGCACTGGAGAAAACGGGCTATCGCTTAAAGCCGGCGGTGCT
GGTCCTGAAGGGCATGGAGCCGAGCGCGGCGGAGGCGGCTTTGGAGCGGCATGGCGGTGATCTTCATGCGGTGCTTGGAA
TAAAGACGGTCTGA

Upstream 100 bases:

>100_bases
GGGCGCTGAAACGCAGTCCAAACGGCCCAGGCTGGCGTTTATTTGACCAGGATCTTCCGATGATACATTGGTATCGCATT
GTTCCTATTGGAGCGGAAAA

Downstream 100 bases:

>100_bases
TGTAAACGGAGACCAAACGGTGAGTGAGCGATCGCGGATGTTCCGGGAAACGGGCGAAGCACCGGAAGCCGTTCACAGGC
TTCTTCAACGTGAAGGCAGG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MVSLHTESTGDRYRDLELAPDGELLRMMLDGQKNAFSAVSDALPALESALAAMVKRLRGSAGRLFYVGAGTSGRLAVLDA
LELGPTFSWPDERLVLLLAGGLGLAGVAEAAEDDIHAAVRAIENAGCGHDDVILALAASGTTPYTLAAVEAARKCGALTI
GLANNPGAPLLGRAEIGILLDTGPEAVAGSTRLAAGTSQKIALNLLSTALMARLGKVFRGQMVDMKAANDKLHRRAATIL
VEISGCSREEAVAALEKTGYRLKPAVLVLKGMEPSAAEAALERHGGDLHAVLGIKTV

Sequences:

>Translated_297_residues
MVSLHTESTGDRYRDLELAPDGELLRMMLDGQKNAFSAVSDALPALESALAAMVKRLRGSAGRLFYVGAGTSGRLAVLDA
LELGPTFSWPDERLVLLLAGGLGLAGVAEAAEDDIHAAVRAIENAGCGHDDVILALAASGTTPYTLAAVEAARKCGALTI
GLANNPGAPLLGRAEIGILLDTGPEAVAGSTRLAAGTSQKIALNLLSTALMARLGKVFRGQMVDMKAANDKLHRRAATIL
VEISGCSREEAVAALEKTGYRLKPAVLVLKGMEPSAAEAALERHGGDLHAVLGIKTV
>Mature_297_residues
MVSLHTESTGDRYRDLELAPDGELLRMMLDGQKNAFSAVSDALPALESALAAMVKRLRGSAGRLFYVGAGTSGRLAVLDA
LELGPTFSWPDERLVLLLAGGLGLAGVAEAAEDDIHAAVRAIENAGCGHDDVILALAASGTTPYTLAAVEAARKCGALTI
GLANNPGAPLLGRAEIGILLDTGPEAVAGSTRLAAGTSQKIALNLLSTALMARLGKVFRGQMVDMKAANDKLHRRAATIL
VEISGCSREEAVAALEKTGYRLKPAVLVLKGMEPSAAEAALERHGGDLHAVLGIKTV

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=272, Percent_Identity=41.9117647058824, Blast_Score=190, Evalue=8e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30677; Mature: 30677

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLHTESTGDRYRDLELAPDGELLRMMLDGQKNAFSAVSDALPALESALAAMVKRLRGS
CEEECCCCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGRLFYVGAGTSGRLAVLDALELGPTFSWPDERLVLLLAGGLGLAGVAEAAEDDIHAAVR
CCCEEEEECCCCCCEEEEEHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
AIENAGCGHDDVILALAASGTTPYTLAAVEAARKCGALTIGLANNPGAPLLGRAEIGILL
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCCCCCEECCCEEEEEE
DTGPEAVAGSTRLAAGTSQKIALNLLSTALMARLGKVFRGQMVDMKAANDKLHRRAATIL
ECCCCHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHEEEEE
VEISGCSREEAVAALEKTGYRLKPAVLVLKGMEPSAAEAALERHGGDLHAVLGIKTV
EEECCCCHHHHHHHHHHCCCEECCEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MVSLHTESTGDRYRDLELAPDGELLRMMLDGQKNAFSAVSDALPALESALAAMVKRLRGS
CEEECCCCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGRLFYVGAGTSGRLAVLDALELGPTFSWPDERLVLLLAGGLGLAGVAEAAEDDIHAAVR
CCCEEEEECCCCCCEEEEEHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
AIENAGCGHDDVILALAASGTTPYTLAAVEAARKCGALTIGLANNPGAPLLGRAEIGILL
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEEECCCCCCCEECCCEEEEEE
DTGPEAVAGSTRLAAGTSQKIALNLLSTALMARLGKVFRGQMVDMKAANDKLHRRAATIL
ECCCCHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHEEEEE
VEISGCSREEAVAALEKTGYRLKPAVLVLKGMEPSAAEAALERHGGDLHAVLGIKTV
EEECCCCHHHHHHHHHHCCCEECCEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]