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The map label for this gene is glmS [H]

Identifier: 110635197

GI number: 110635197

Start: 3115339

End: 3116349

Strand: Reverse

Name: glmS [H]

Synonym: Meso_2864

Alternate gene names: 110635197

Gene position: 3116349-3115339 (Counterclockwise)

Preceding gene: 110635198

Following gene: 110635196

Centisome position: 70.63

GC content: 64.39

Gene sequence:

>1011_bases
ATGTTCCGGGAAACGGGCGAAGCACCGGAAGCCGTTCACAGGCTTCTTCAACGTGAAGGCAGGACATTCCGCGAGATCGG
CCGGCTCGTTGCGGAGCGGCGCCCGGCGGTGGTCACAGTCGCGGCCCGCGGTTCGTCCGACCATGCCGTCAGCTTCTTCA
AATATCTCTTCGAGATCTCCTGCGGCATCCCGGTAGCGTCCATCGGGCCGTCCGTCGCCTCGGTTTATCATGCTTCCCTG
CGCGTGCCGGGCGGGCTGCACATTACCGTTTCGCAGTCTGGGGCCAGTCCTGACATCATCGCCGTGCAGGATGAAGCCAA
GCGCGGCGGTGCCCTGACCGTGGCCGTGGTCAATGTGGCCGAGAGTCCGCTTGCACGTGCCGCCGATATCGTGCTTCCCA
TCCATGCCGGCGAGGAAAAGAGCGTGGCGGCCACGAAAAGCTTTATCGCCTCGGCGGCAGCGCTCGCAGCGGTGACCCAG
GCCGCATCGGGCAGCGAGGCGCTTGCGGCGGGGCTTGCAAGGCTGCCGGAGGCGCTCAAGGCCGCCTGCCAGGCAGATTA
CGAACGGGCCATGCCGCTGCTGCTAAAAGCACAATCGCTGTTCACCGGCGGGCGCGGGCCGGGCTTTGCCATCGCCCTTG
AAGCGGCGCTTAAGGCCAAGGAGACGGCAAAGCTTCACGCCGAGGCATTTTCCCTCGCCGAACTTATGCACGGCCCGATG
CAACTCGTGGAGGAAGGGTTCCCCATTCTCGCCTTTGCGCCGGAGGATGAGGCGCTTTCTTCGAGCATGGCAGTCATGGA
AACGCTGCGCGGCATGGGCGCCTGCATCGTCGCCTTCTCCTCGCGGCCGACCGGGCAAGATACGATTGCCGTGCCGTCAA
CAGGTTATGGCCAATTAGACCCGCTGGCGGCACTTGCCGCCTATTACCGGCTGGTGGAGCGGCTTGCGCGCGAGCGCGGA
TTCAACCCCGATACGCCAGACAAGCTTAAGAAGGTGACGGAGACGATCTGA

Upstream 100 bases:

>100_bases
GAGGCGGCTTTGGAGCGGCATGGCGGTGATCTTCATGCGGTGCTTGGAATAAAGACGGTCTGATGTAAACGGAGACCAAA
CGGTGAGTGAGCGATCGCGG

Downstream 100 bases:

>100_bases
TGGACATAACCATCCTCGCCGGGGCGCGCCTGTTTGATGGTGAGCGCTTCATCGACCGGCACGCTCTCGTCGTGGTGGCT
GGTCGCGTTAGGGATATCGT

Product: sugar isomerase (SIS)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MFRETGEAPEAVHRLLQREGRTFREIGRLVAERRPAVVTVAARGSSDHAVSFFKYLFEISCGIPVASIGPSVASVYHASL
RVPGGLHITVSQSGASPDIIAVQDEAKRGGALTVAVVNVAESPLARAADIVLPIHAGEEKSVAATKSFIASAAALAAVTQ
AASGSEALAAGLARLPEALKAACQADYERAMPLLLKAQSLFTGGRGPGFAIALEAALKAKETAKLHAEAFSLAELMHGPM
QLVEEGFPILAFAPEDEALSSSMAVMETLRGMGACIVAFSSRPTGQDTIAVPSTGYGQLDPLAALAAYYRLVERLARERG
FNPDTPDKLKKVTETI

Sequences:

>Translated_336_residues
MFRETGEAPEAVHRLLQREGRTFREIGRLVAERRPAVVTVAARGSSDHAVSFFKYLFEISCGIPVASIGPSVASVYHASL
RVPGGLHITVSQSGASPDIIAVQDEAKRGGALTVAVVNVAESPLARAADIVLPIHAGEEKSVAATKSFIASAAALAAVTQ
AASGSEALAAGLARLPEALKAACQADYERAMPLLLKAQSLFTGGRGPGFAIALEAALKAKETAKLHAEAFSLAELMHGPM
QLVEEGFPILAFAPEDEALSSSMAVMETLRGMGACIVAFSSRPTGQDTIAVPSTGYGQLDPLAALAAYYRLVERLARERG
FNPDTPDKLKKVTETI
>Mature_336_residues
MFRETGEAPEAVHRLLQREGRTFREIGRLVAERRPAVVTVAARGSSDHAVSFFKYLFEISCGIPVASIGPSVASVYHASL
RVPGGLHITVSQSGASPDIIAVQDEAKRGGALTVAVVNVAESPLARAADIVLPIHAGEEKSVAATKSFIASAAALAAVTQ
AASGSEALAAGLARLPEALKAACQADYERAMPLLLKAQSLFTGGRGPGFAIALEAALKAKETAKLHAEAFSLAELMHGPM
QLVEEGFPILAFAPEDEALSSSMAVMETLRGMGACIVAFSSRPTGQDTIAVPSTGYGQLDPLAALAAYYRLVERLARERG
FNPDTPDKLKKVTETI

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=263, Percent_Identity=29.277566539924, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI4826742, Length=264, Percent_Identity=29.5454545454545, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790167, Length=305, Percent_Identity=31.4754098360656, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17532899, Length=260, Percent_Identity=28.8461538461538, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17532897, Length=260, Percent_Identity=28.8461538461538, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17539970, Length=260, Percent_Identity=28.0769230769231, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322745, Length=369, Percent_Identity=28.1842818428184, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357745, Length=268, Percent_Identity=27.6119402985075, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35175; Mature: 35175

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRETGEAPEAVHRLLQREGRTFREIGRLVAERRPAVVTVAARGSSDHAVSFFKYLFEIS
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHH
CGIPVASIGPSVASVYHASLRVPGGLHITVSQSGASPDIIAVQDEAKRGGALTVAVVNVA
CCCCHHHCCHHHHHHHHHHEECCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEEHH
ESPLARAADIVLPIHAGEEKSVAATKSFIASAAALAAVTQAASGSEALAAGLARLPEALK
HCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AACQADYERAMPLLLKAQSLFTGGRGPGFAIALEAALKAKETAKLHAEAFSLAELMHGPM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVEEGFPILAFAPEDEALSSSMAVMETLRGMGACIVAFSSRPTGQDTIAVPSTGYGQLD
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCCC
PLAALAAYYRLVERLARERGFNPDTPDKLKKVTETI
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MFRETGEAPEAVHRLLQREGRTFREIGRLVAERRPAVVTVAARGSSDHAVSFFKYLFEIS
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHH
CGIPVASIGPSVASVYHASLRVPGGLHITVSQSGASPDIIAVQDEAKRGGALTVAVVNVA
CCCCHHHCCHHHHHHHHHHEECCCCEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEEHH
ESPLARAADIVLPIHAGEEKSVAATKSFIASAAALAAVTQAASGSEALAAGLARLPEALK
HCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AACQADYERAMPLLLKAQSLFTGGRGPGFAIALEAALKAKETAKLHAEAFSLAELMHGPM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVEEGFPILAFAPEDEALSSSMAVMETLRGMGACIVAFSSRPTGQDTIAVPSTGYGQLD
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCCCCCCC
PLAALAAYYRLVERLARERGFNPDTPDKLKKVTETI
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA