Click here to switch to the map view.

The map label for this gene is eda [H]

Identifier: 110635067

GI number: 110635067

Start: 2973853

End: 2974494

Strand: Reverse

Name: eda [H]

Synonym: Meso_2733

Alternate gene names: 110635067

Gene position: 2974494-2973853 (Counterclockwise)

Preceding gene: 110635068

Following gene: 110635064

Centisome position: 67.41

GC content: 62.77

Gene sequence:

>642_bases
ATGAAAAAGAAGACCGAGAAGCTTTTGGAAATTCTCACGGCGCAGCCAGTCATCCCCGTTTTGAAGATCGACAGGCTCTC
GGACGCGGTACCGCTGGCAAGGGCACTTGCAAAGGGTGGCCTGCCGGCGATCGAGATCACGCTGCGCACGCCGAACGCGA
TCGATGCGATCCGCCTTGTCGTCGATGAGGTGCCGGAAGCGATCGTCGGAGCCGGTACGGTTCTGACGAAGAAAGACTTC
GCAAGGGCGGAGCAAGCGGGGGCAAGATTCATTGTCTCTCCGGGCACGACGCAGGAGCTTTTGGACGCGGCGGAAGGTTC
CCTTGTGCCGTTCCTGCCGGGCGCCGTGACCCCGAGCGAGATCATGGCGCTGCGGGAGGAAGATTACCGTGTTCTCAAAT
TCTTCCCGGCCGAGCAGGCGGGCGGGGCGGCATTCCTGAAATCCCTTGCCTCGCCGCTCGCCGATATGCGGTTCTGCCCG
ACGGGCGGGATTTCGCCGAAGAATGCGGGCGATTATCTGTCCTTGCCCAACATCGTCTGCGTGGGCGGCTCATGGGTGGC
ACCGGATGCCGAGCTTGCGGCCGGCAATTGGGCGGCAGTGGAAGAGCTCGCGCGTCAAACGGCGGGACTGCGCCAAGGAT
AG

Upstream 100 bases:

>100_bases
TAGTGCATAAGCACGATGCGTGTATTCAATAATTTGCAGCGTTCTTCCTTAAAGGACGCAAGGTGCTGTAAGACAGTCGT
ATCATCCACAGGAGCCGCCG

Downstream 100 bases:

>100_bases
CGCTCAAGCCTTGGGGGAAAGAGCCGCCCTGAAAGGAGCGGCTCCGGCGTTTATTCGAATTTTGCGAGCGAAAGGAAGAC
GACAGCCTTGCCGCTAAAGC

Product: keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase

Products: NA

Alternate protein names: KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKKKTEKLLEILTAQPVIPVLKIDRLSDAVPLARALAKGGLPAIEITLRTPNAIDAIRLVVDEVPEAIVGAGTVLTKKDF
ARAEQAGARFIVSPGTTQELLDAAEGSLVPFLPGAVTPSEIMALREEDYRVLKFFPAEQAGGAAFLKSLASPLADMRFCP
TGGISPKNAGDYLSLPNIVCVGGSWVAPDAELAAGNWAAVEELARQTAGLRQG

Sequences:

>Translated_213_residues
MKKKTEKLLEILTAQPVIPVLKIDRLSDAVPLARALAKGGLPAIEITLRTPNAIDAIRLVVDEVPEAIVGAGTVLTKKDF
ARAEQAGARFIVSPGTTQELLDAAEGSLVPFLPGAVTPSEIMALREEDYRVLKFFPAEQAGGAAFLKSLASPLADMRFCP
TGGISPKNAGDYLSLPNIVCVGGSWVAPDAELAAGNWAAVEELARQTAGLRQG
>Mature_213_residues
MKKKTEKLLEILTAQPVIPVLKIDRLSDAVPLARALAKGGLPAIEITLRTPNAIDAIRLVVDEVPEAIVGAGTVLTKKDF
ARAEQAGARFIVSPGTTQELLDAAEGSLVPFLPGAVTPSEIMALREEDYRVLKFFPAEQAGGAAFLKSLASPLADMRFCP
TGGISPKNAGDYLSLPNIVCVGGSWVAPDAELAAGNWAAVEELARQTAGLRQG

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=206, Percent_Identity=48.0582524271845, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI48994954, Length=167, Percent_Identity=28.7425149700599, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.2.14 [H]

Molecular weight: Translated: 22383; Mature: 22383

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKTEKLLEILTAQPVIPVLKIDRLSDAVPLARALAKGGLPAIEITLRTPNAIDAIRLV
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
VDEVPEAIVGAGTVLTKKDFARAEQAGARFIVSPGTTQELLDAAEGSLVPFLPGAVTPSE
HHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHH
IMALREEDYRVLKFFPAEQAGGAAFLKSLASPLADMRFCPTGGISPKNAGDYLSLPNIVC
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCCCCCCEEE
VGGSWVAPDAELAAGNWAAVEELARQTAGLRQG
ECCCEECCCCHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKKTEKLLEILTAQPVIPVLKIDRLSDAVPLARALAKGGLPAIEITLRTPNAIDAIRLV
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
VDEVPEAIVGAGTVLTKKDFARAEQAGARFIVSPGTTQELLDAAEGSLVPFLPGAVTPSE
HHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHH
IMALREEDYRVLKFFPAEQAGGAAFLKSLASPLADMRFCPTGGISPKNAGDYLSLPNIVC
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCCCCCCEEE
VGGSWVAPDAELAAGNWAAVEELARQTAGLRQG
ECCCEECCCCHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]