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The map label for this gene is pabB [H]

Identifier: 110635063

GI number: 110635063

Start: 2967053

End: 2968210

Strand: Reverse

Name: pabB [H]

Synonym: Meso_2729

Alternate gene names: 110635063

Gene position: 2968210-2967053 (Counterclockwise)

Preceding gene: 110635064

Following gene: 110635062

Centisome position: 67.27

GC content: 61.92

Gene sequence:

>1158_bases
ATGTGCCAGCCCTCGCGCGCTACTACCCTAGCGCTCTTCCGCAACGACCTTACGGATGAGACCCTGTGCTTCTCCGTGCC
GGAGGAAATTCTTCAGGCGGACGATCCGGAAGACCTTTTTCCCATGCTGGAAAAGGCAGAAGCACTCCGCCGCGCGGGCA
AGTGGCTTGCAGGCTACATCTCCTATGAAGCTGGCTATCTGTTGGAACCCTCCCTCGTCCGGCACCTGCCGGAAGGTCGT
CGCGCGCCTCTTTTATGCCTCGGCGTCTTCGGCGAGCCGTCAGGCGTTTTGCAAGACACTTCTTCTTCAGGCCAGCCGCC
GCGCCTCTTCGACTTCAAGCTAGCCTGGACTTTTGAGGATTACCGGACCCGCTTCGAGCAGCTTCACCGCCATCTGCGGC
TGGGCGATTGCTACCAGGGCAATCTCACCTTCCCCGTGCATGCTCGCTGGGAGGGCGATCCGCTCACGCTTTTCCAGGCG
CTGACGGCGCGCCAGCCGGTGCGCTATGCGGCTTTCATTAATCTGGGCGGCCCGGTGGTGCTCTCACGCTCGCCCGAACT
CTTTTTCGAGATCTCCGCCGATGGCTGGATCGAAACGCTTCCCATGAAGGGCACGATGCCGCGGGGCAAGACGCCTCGCG
AAGACGAAGCGCTGAAGGAAGCCCTGCGCAACGACCCGAAGAACCAGGCGGAAAACCGCATGATCGTCGACCTCCTGCGC
AACGACATCTCGCGCATTTCGCAGGTCGGCACGCTCGACGTGCCGGAGCTTTTTCACGTGGAGAGCTACCCCACTGTCCA
CCAGATGATCAGCCGCGTTCGGGCAAAGCTGTGCGACGGGCTGGCGCTGGCCGATATTCTCGCCGCACTCTTTCCCTGCG
GCTCGGTCACCGGTGCTCCGAAGATTTCCGCCATGAAGATCCTGCGGGAACTTGAGGCAACCCCGCGGGATGTTTACTGC
GGCGCCATCGGCTGGGCGGCACCCGACGGGCGCATGCGCTTCAGTGTGGCGATCCGCACCATTTCTCTCTATCCGGGCGG
TGATGCAGTCTTTAATGTCGGCGGCGGTGTGGTCTTTGATTCCACCGCCCGCGATGAATATGACGAATGCCTGCTGAAGG
CCCGATTCGCCACCAGCGAAATTTGCGCTGCGCCCTGA

Upstream 100 bases:

>100_bases
TGCATCCGACCCCGCCTTCTGGACCAAGGGCCTCTCGGTCATCGAAAGCTTGATCGACGAACTGGAAGCGCTGGAGGAAG
GCTGATCGCCTTTGAAGGAG

Downstream 100 bases:

>100_bases
AAACCGACCACCGGAGCCTTACCTTTCATGTTCATCGTTTCGCTTGAATATGTCGTGCCCATCGAAGAGATCGAGCCACA
CGTTTCCGGCCACATGCAGT

Product: aminodeoxychorismate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MCQPSRATTLALFRNDLTDETLCFSVPEEILQADDPEDLFPMLEKAEALRRAGKWLAGYISYEAGYLLEPSLVRHLPEGR
RAPLLCLGVFGEPSGVLQDTSSSGQPPRLFDFKLAWTFEDYRTRFEQLHRHLRLGDCYQGNLTFPVHARWEGDPLTLFQA
LTARQPVRYAAFINLGGPVVLSRSPELFFEISADGWIETLPMKGTMPRGKTPREDEALKEALRNDPKNQAENRMIVDLLR
NDISRISQVGTLDVPELFHVESYPTVHQMISRVRAKLCDGLALADILAALFPCGSVTGAPKISAMKILRELEATPRDVYC
GAIGWAAPDGRMRFSVAIRTISLYPGGDAVFNVGGGVVFDSTARDEYDECLLKARFATSEICAAP

Sequences:

>Translated_385_residues
MCQPSRATTLALFRNDLTDETLCFSVPEEILQADDPEDLFPMLEKAEALRRAGKWLAGYISYEAGYLLEPSLVRHLPEGR
RAPLLCLGVFGEPSGVLQDTSSSGQPPRLFDFKLAWTFEDYRTRFEQLHRHLRLGDCYQGNLTFPVHARWEGDPLTLFQA
LTARQPVRYAAFINLGGPVVLSRSPELFFEISADGWIETLPMKGTMPRGKTPREDEALKEALRNDPKNQAENRMIVDLLR
NDISRISQVGTLDVPELFHVESYPTVHQMISRVRAKLCDGLALADILAALFPCGSVTGAPKISAMKILRELEATPRDVYC
GAIGWAAPDGRMRFSVAIRTISLYPGGDAVFNVGGGVVFDSTARDEYDECLLKARFATSEICAAP
>Mature_385_residues
MCQPSRATTLALFRNDLTDETLCFSVPEEILQADDPEDLFPMLEKAEALRRAGKWLAGYISYEAGYLLEPSLVRHLPEGR
RAPLLCLGVFGEPSGVLQDTSSSGQPPRLFDFKLAWTFEDYRTRFEQLHRHLRLGDCYQGNLTFPVHARWEGDPLTLFQA
LTARQPVRYAAFINLGGPVVLSRSPELFFEISADGWIETLPMKGTMPRGKTPREDEALKEALRNDPKNQAENRMIVDLLR
NDISRISQVGTLDVPELFHVESYPTVHQMISRVRAKLCDGLALADILAALFPCGSVTGAPKISAMKILRELEATPRDVYC
GAIGWAAPDGRMRFSVAIRTISLYPGGDAVFNVGGGVVFDSTARDEYDECLLKARFATSEICAAP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=263, Percent_Identity=42.2053231939163, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787518, Length=240, Percent_Identity=33.75, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786809, Length=222, Percent_Identity=24.3243243243243, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=402, Percent_Identity=30.5970149253731, Blast_Score=162, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=282, Percent_Identity=30.8510638297872, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 42798; Mature: 42798

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCQPSRATTLALFRNDLTDETLCFSVPEEILQADDPEDLFPMLEKAEALRRAGKWLAGYI
CCCCCCHHHHHHHHCCCCCCCEEHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SYEAGYLLEPSLVRHLPEGRRAPLLCLGVFGEPSGVLQDTSSSGQPPRLFDFKLAWTFED
HHCCCCEECHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEHHH
YRTRFEQLHRHLRLGDCYQGNLTFPVHARWEGDPLTLFQALTARQPVRYAAFINLGGPVV
HHHHHHHHHHHCCCCCEECCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCEE
LSRSPELFFEISADGWIETLPMKGTMPRGKTPREDEALKEALRNDPKNQAENRMIVDLLR
EECCCCEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
NDISRISQVGTLDVPELFHVESYPTVHQMISRVRAKLCDGLALADILAALFPCGSVTGAP
HHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
KISAMKILRELEATPRDVYCGAIGWAAPDGRMRFSVAIRTISLYPGGDAVFNVGGGVVFD
CHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEEEEEEECCCCCEEEECCCCEEEC
STARDEYDECLLKARFATSEICAAP
CCCCHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MCQPSRATTLALFRNDLTDETLCFSVPEEILQADDPEDLFPMLEKAEALRRAGKWLAGYI
CCCCCCHHHHHHHHCCCCCCCEEHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SYEAGYLLEPSLVRHLPEGRRAPLLCLGVFGEPSGVLQDTSSSGQPPRLFDFKLAWTFED
HHCCCCEECHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEHHH
YRTRFEQLHRHLRLGDCYQGNLTFPVHARWEGDPLTLFQALTARQPVRYAAFINLGGPVV
HHHHHHHHHHHCCCCCEECCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCEE
LSRSPELFFEISADGWIETLPMKGTMPRGKTPREDEALKEALRNDPKNQAENRMIVDLLR
EECCCCEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
NDISRISQVGTLDVPELFHVESYPTVHQMISRVRAKLCDGLALADILAALFPCGSVTGAP
HHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
KISAMKILRELEATPRDVYCGAIGWAAPDGRMRFSVAIRTISLYPGGDAVFNVGGGVVFD
CHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEEEEEEECCCCCEEEECCCCEEEC
STARDEYDECLLKARFATSEICAAP
CCCCHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]