Click here to switch to the map view.

The map label for this gene is hss [H]

Identifier: 110635061

GI number: 110635061

Start: 2965185

End: 2966630

Strand: Reverse

Name: hss [H]

Synonym: Meso_2727

Alternate gene names: 110635061

Gene position: 2966630-2965185 (Counterclockwise)

Preceding gene: 110635062

Following gene: 110635060

Centisome position: 67.23

GC content: 61.27

Gene sequence:

>1446_bases
ATGGCTGAGAAGAACTGGCCCATTCATGGAACGATCACCGGCCCTGTCGTGATGATCGGCTTCGGCTCGATCGGCCGCGG
AATGCTGCCCCTCATTGAGCGCCATTTCCGTTTCGACAAATCCCGCATGGTGGTGATCGATCCCGTCGACACCGACCGCA
AGCTTTTGGACGAGCGCAGCATCCGCTTCATCCAGACCCATGTCACGAGGGAGAATTACCGCGAACTCCTCACGCCCCTT
TTGACCGAGGGCACCGGCCAGGGCTTTTGCGTCAACCTCTCGGTTGACACCTCCTCTCTCGACCTGATGAAGCTCTGCCG
CGAGCTCGGCGTGCTCTACATCGATACCGTTGTAGAGCCGTGGCTCGGTTTTTATTTCGATACTTCCGTGAGCAACGAAT
CGCGCACGAACTATGCGCTGCGCGAGACGGTCCGCGAAGAAAAGCGAAGGAGCCCCGGCGGCACGACGGCGGTCTCCACC
TGCGGGGCAAATCCAGGCATGGTCTCCTGGTTCGTCAAGCAGGCGCTCGTCCATCTCGCGCAGGATATGATGCTCGAATT
TGAAGAGCCTGGCCCTTACGATCGCGAAGGCTGGGCGGCTCTCATGCGGAAGGTGGGCGTGAAAGGCATCCACATAGCCG
AGCGCGACACCCAGCGCACCCGCAAGCCCAAGCCTATGAACGTCTTTTGGAACACCTGGTCGGTGGAGGGTTTCATTTCC
GAGGGCCTGCAGCCGGCCGAGCTTGGCTGGGGCACGCACGAGAAATGGATGCCGTCGAACGCGCGTGGGCACGACAAGGG
CTGCATGGCGGGGATCTACCTGGAGCAGCCGGGGGCCAACACCCGCGTACGCACCTGGTGCCCCACGCCCGGCGCGCAAT
ACGGGTTCCTCGTCACGCACAACGAAGCGATCTCGATAGCCGACTTCTTCACCGTTCGGGACGAGAGCGGCGATGTAATC
TATCGCCCGACTTGCAATTACGCTTATCACCCCTGCAACGACGCGGTGCTCTCGCTGCACGAGATGTTCGGGGCTGGCGG
CAAGGCGCAGCCCGTCCAACATGTTCTGGACGAAAAGGAGCTCGTGGACGGGGTCGATGAGCTTGGTGTGCTCCTCTACG
GCCATGACAAGAACGCCTACTGGTATGGCTCGCAGCTCTCCCTGGAAGAGGCGCGGGAGCTTGCGCCTTACCAGAATGCC
ACGGGCCTGCAGGTGACCTCCGCAGTGCTTGCCGGCATGGTCTGGGCGCTCGAAAACCCCGAGGCCGGCATTGTCGAGGC
CGATGAGGTTGACTATCGCCGCTGCCTGGAAGTTCAGCTTCCCTATCTCGGCCCGGTTAAGGGCTATTATACCGACTGGA
CACCGCTTGAGGGGCGTCCTGGCCTTTTCTCCGAGGAGATCGACCAGTCCGACCCATGGCAATTTCGCAACATCCTCGTG
CGGTAA

Upstream 100 bases:

>100_bases
GAGGCATGAAGGGCTCTTTGGTCATTCCCGCTTTATTGTGACGCCGTTCTGTGTTTTGAGCTGGCAGTCCTAAATCGACC
AATGAGGAGAAACCACTGAA

Downstream 100 bases:

>100_bases
TGCTCCTCTGACCGCATGACGGGTTGCATTCGCGGCAAAAGTGCGGCGAATGGAAATGTCACTTACAGAGGAGGCGGGTA
TGATTTCCTTTCGCTCAGCG

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MAEKNWPIHGTITGPVVMIGFGSIGRGMLPLIERHFRFDKSRMVVIDPVDTDRKLLDERSIRFIQTHVTRENYRELLTPL
LTEGTGQGFCVNLSVDTSSLDLMKLCRELGVLYIDTVVEPWLGFYFDTSVSNESRTNYALRETVREEKRRSPGGTTAVST
CGANPGMVSWFVKQALVHLAQDMMLEFEEPGPYDREGWAALMRKVGVKGIHIAERDTQRTRKPKPMNVFWNTWSVEGFIS
EGLQPAELGWGTHEKWMPSNARGHDKGCMAGIYLEQPGANTRVRTWCPTPGAQYGFLVTHNEAISIADFFTVRDESGDVI
YRPTCNYAYHPCNDAVLSLHEMFGAGGKAQPVQHVLDEKELVDGVDELGVLLYGHDKNAYWYGSQLSLEEARELAPYQNA
TGLQVTSAVLAGMVWALENPEAGIVEADEVDYRRCLEVQLPYLGPVKGYYTDWTPLEGRPGLFSEEIDQSDPWQFRNILV
R

Sequences:

>Translated_481_residues
MAEKNWPIHGTITGPVVMIGFGSIGRGMLPLIERHFRFDKSRMVVIDPVDTDRKLLDERSIRFIQTHVTRENYRELLTPL
LTEGTGQGFCVNLSVDTSSLDLMKLCRELGVLYIDTVVEPWLGFYFDTSVSNESRTNYALRETVREEKRRSPGGTTAVST
CGANPGMVSWFVKQALVHLAQDMMLEFEEPGPYDREGWAALMRKVGVKGIHIAERDTQRTRKPKPMNVFWNTWSVEGFIS
EGLQPAELGWGTHEKWMPSNARGHDKGCMAGIYLEQPGANTRVRTWCPTPGAQYGFLVTHNEAISIADFFTVRDESGDVI
YRPTCNYAYHPCNDAVLSLHEMFGAGGKAQPVQHVLDEKELVDGVDELGVLLYGHDKNAYWYGSQLSLEEARELAPYQNA
TGLQVTSAVLAGMVWALENPEAGIVEADEVDYRRCLEVQLPYLGPVKGYYTDWTPLEGRPGLFSEEIDQSDPWQFRNILV
R
>Mature_480_residues
AEKNWPIHGTITGPVVMIGFGSIGRGMLPLIERHFRFDKSRMVVIDPVDTDRKLLDERSIRFIQTHVTRENYRELLTPLL
TEGTGQGFCVNLSVDTSSLDLMKLCRELGVLYIDTVVEPWLGFYFDTSVSNESRTNYALRETVREEKRRSPGGTTAVSTC
GANPGMVSWFVKQALVHLAQDMMLEFEEPGPYDREGWAALMRKVGVKGIHIAERDTQRTRKPKPMNVFWNTWSVEGFISE
GLQPAELGWGTHEKWMPSNARGHDKGCMAGIYLEQPGANTRVRTWCPTPGAQYGFLVTHNEAISIADFFTVRDESGDVIY
RPTCNYAYHPCNDAVLSLHEMFGAGGKAQPVQHVLDEKELVDGVDELGVLLYGHDKNAYWYGSQLSLEEARELAPYQNAT
GLQVTSAVLAGMVWALENPEAGIVEADEVDYRRCLEVQLPYLGPVKGYYTDWTPLEGRPGLFSEEIDQSDPWQFRNILVR

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 54208; Mature: 54077

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKNWPIHGTITGPVVMIGFGSIGRGMLPLIERHFRFDKSRMVVIDPVDTDRKLLDERS
CCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHH
IRFIQTHVTRENYRELLTPLLTEGTGQGFCVNLSVDTSSLDLMKLCRELGVLYIDTVVEP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCEEEHHHHHHH
WLGFYFDTSVSNESRTNYALRETVREEKRRSPGGTTAVSTCGANPGMVSWFVKQALVHLA
HHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
QDMMLEFEEPGPYDREGWAALMRKVGVKGIHIAERDTQRTRKPKPMNVFWNTWSVEGFIS
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCEEEEECEEEHHHHH
EGLQPAELGWGTHEKWMPSNARGHDKGCMAGIYLEQPGANTRVRTWCPTPGAQYGFLVTH
CCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEC
NEAISIADFFTVRDESGDVIYRPTCNYAYHPCNDAVLSLHEMFGAGGKAQPVQHVLDEKE
CCEEEEEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVDGVDELGVLLYGHDKNAYWYGSQLSLEEARELAPYQNATGLQVTSAVLAGMVWALENP
HHCCHHHCCEEEEECCCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCC
EAGIVEADEVDYRRCLEVQLPYLGPVKGYYTDWTPLEGRPGLFSEEIDQSDPWQFRNILV
CCCCEECCCCCHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHC
R
C
>Mature Secondary Structure 
AEKNWPIHGTITGPVVMIGFGSIGRGMLPLIERHFRFDKSRMVVIDPVDTDRKLLDERS
CCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHH
IRFIQTHVTRENYRELLTPLLTEGTGQGFCVNLSVDTSSLDLMKLCRELGVLYIDTVVEP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCEEEHHHHHHH
WLGFYFDTSVSNESRTNYALRETVREEKRRSPGGTTAVSTCGANPGMVSWFVKQALVHLA
HHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHH
QDMMLEFEEPGPYDREGWAALMRKVGVKGIHIAERDTQRTRKPKPMNVFWNTWSVEGFIS
HHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCEEEEECEEEHHHHH
EGLQPAELGWGTHEKWMPSNARGHDKGCMAGIYLEQPGANTRVRTWCPTPGAQYGFLVTH
CCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEC
NEAISIADFFTVRDESGDVIYRPTCNYAYHPCNDAVLSLHEMFGAGGKAQPVQHVLDEKE
CCEEEEEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
LVDGVDELGVLLYGHDKNAYWYGSQLSLEEARELAPYQNATGLQVTSAVLAGMVWALENP
HHCCHHHCCEEEEECCCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCC
EAGIVEADEVDYRRCLEVQLPYLGPVKGYYTDWTPLEGRPGLFSEEIDQSDPWQFRNILV
CCCCEECCCCCHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]