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The map label for this gene is treZ [H]

Identifier: 110635009

GI number: 110635009

Start: 2903645

End: 2905468

Strand: Reverse

Name: treZ [H]

Synonym: Meso_2675

Alternate gene names: 110635009

Gene position: 2905468-2903645 (Counterclockwise)

Preceding gene: 110635010

Following gene: 110635008

Centisome position: 65.85

GC content: 61.68

Gene sequence:

>1824_bases
ATGACCCACACAACTTTCCAGACACGCTGGGGCGCTCAGCTCCAGGATGACGATACCGCTCTTTTCCGCCTCTGGGCGCC
GGCGGCGGACCAACTTCGCCTGCGCTTTGGAGGGGGCGAAGAGCGCGCGATGGAGCGCGGCCAAGGCGGCTGGTTCGAAT
TGGAAATCGGTGGCCTCGCGGCAGGGACACCGTACCAGTTCGTGCTGCCCGACGGCACTGCGGTGCCGGACCCTGCCTCC
CGTGCACAGGCGGGTGACGTGCATGGACCAAGCCTGTTGACGAGCCGCGATTTCAATTGGGGTGTGAAGGATTGGAAGGG
GCGGCCCTGGGAAGAGGCGGTCGTTTATGAGCTTCATCCTGGCACATTTTCCCCGGAAGGCGGCTCCGGCGGCATCCGGC
GCAAGCTCGATTACCTGGCCGAAGTCGGGTTCACGGCGATCGAGATCATGCCGGTCGCGCAGTTTTCCGGCAATCGCGGC
TGGGGCTATGACGGCGTGCTCCCCTATTGCCCGCATTCGGCCTATGGAGGCGTGGCCGGCCTGAAGGAACTCGTTGATGC
CGCGCATGAGCGCGGGCTGATGATGATCCTGGATGTGGTCTACAACCACTTTGGCCCTGACGGGAATTATCTCAGCCTCT
ATGCGCCCGATTTCTTCGATCCCTCGCGGGATACGCCATGGGGACCGGCCATCCGTTTCGAGGAGCCGGCGGTGCGTGCC
TTCTTCCTCGACAATCCGATTTACTGGCTGGAGGAGTTCCGCTTCGACGGACTGCGCTTCGATGCGATCGACCAGATAAA
GGACAGAAGCGAGACACCCATTCTTCAGGAGATCGCACGCGCAATTCGTTCGCGATATCCGGACCGGCACATTCATCTCA
TGACAGAGGATGAGCGCAACATCGTGGAACTCCATCCGCGCGACGATGCGAACCGTCCCATCCTCTTCACGGCGGAGTGG
AACGATGATTTCCATCATGCCGCGCATTGCGTCGCGACGGGGGAGGATACCGGTTACTATGCCGCCTTCGCCGACGATCC
CGCCGGCCACCTCGCGCGGGCGCTGGCGGAAGGTTTCTGCTACCAGGGCGAGCCCTACGCGCCGCGGGAGGGAAAGCCGC
GGGGCGTGCCGAGCGCCGGACAACCACCCGCGGCCTTCGTCGATTTCCTGCAAAACCATGATCAGATCGGCAACCGCGCC
TTTGGAGAACGGCTGACTGCGCTAGCAGATGCCGATACGGTCGAGCTTCTGACGGCTGTGCTCTTGCTCAATCCGCAGAT
CCCGCTCGCTTTCATGGGGGAGGAATTCGGCGAGACCAACCCGTTTCTCTTTTTTACCGACTTTCACGGTGATCTTGCGA
AGGCAGTGCGGGAGGGGCGCCGGCACGAATTCAAGGATTTCGGGCACTTCAGCGGCGAACAGGCAGAGCAGATCCCCGAT
CCCAACGCGCTCTCCACCTTCGAGGCCTCCATGCTGGATTGGGACCGGGTGGAAACGGAAGCAGGTCGGAAGCGCCTTGA
TCTTTTCCGGCGGCTTCTACAGGTCCGCAAAGTCCATCTTCTGCCGCACCTGTCGGACATGACATCCATGCAGGGTCATT
CGACACGGCTTGGCGAAAAGGCGTTGTCCGTGCGCTGGCGCATGAGCGATCGCGTATTGGTCATGGCGGCAAATTTCGGC
ACCGCTGCCGTCGATACCGCTGATGGTTTCGTGGGCTGCAAAGCGATCTACGAGAGCAGGAAGGGCGTTGAGGCAGCGCT
GCTCCAGGGAGAATTGCCCGAACGAAGCGTTGCAGTTCTCATTACAGAGGAAGCCGGCACATGA

Upstream 100 bases:

>100_bases
GTACCGATACCGGCCAATGGCCGGTCTGGGAGGCCATGCGTTCTCCGCACACGCTGGAACTCGCCGACCGTTCGATGGTT
GTGCTGGAAGGCCGTGTACG

Downstream 100 bases:

>100_bases
GCGAGGAAGTTGACCGGCTGGCAGCCGCGCACGGTGTCCTGCGCTCCTATCGCGCGCTGGACGGAACCATCTCGCGCGCA
TCGGATGATGCCGTACAGGC

Product: malto-oligosyltrehalose trehalohydrolase

Products: NA

Alternate protein names: MTHase; 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase; Maltooligosyl trehalose trehalohydrolase [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MTHTTFQTRWGAQLQDDDTALFRLWAPAADQLRLRFGGGEERAMERGQGGWFELEIGGLAAGTPYQFVLPDGTAVPDPAS
RAQAGDVHGPSLLTSRDFNWGVKDWKGRPWEEAVVYELHPGTFSPEGGSGGIRRKLDYLAEVGFTAIEIMPVAQFSGNRG
WGYDGVLPYCPHSAYGGVAGLKELVDAAHERGLMMILDVVYNHFGPDGNYLSLYAPDFFDPSRDTPWGPAIRFEEPAVRA
FFLDNPIYWLEEFRFDGLRFDAIDQIKDRSETPILQEIARAIRSRYPDRHIHLMTEDERNIVELHPRDDANRPILFTAEW
NDDFHHAAHCVATGEDTGYYAAFADDPAGHLARALAEGFCYQGEPYAPREGKPRGVPSAGQPPAAFVDFLQNHDQIGNRA
FGERLTALADADTVELLTAVLLLNPQIPLAFMGEEFGETNPFLFFTDFHGDLAKAVREGRRHEFKDFGHFSGEQAEQIPD
PNALSTFEASMLDWDRVETEAGRKRLDLFRRLLQVRKVHLLPHLSDMTSMQGHSTRLGEKALSVRWRMSDRVLVMAANFG
TAAVDTADGFVGCKAIYESRKGVEAALLQGELPERSVAVLITEEAGT

Sequences:

>Translated_607_residues
MTHTTFQTRWGAQLQDDDTALFRLWAPAADQLRLRFGGGEERAMERGQGGWFELEIGGLAAGTPYQFVLPDGTAVPDPAS
RAQAGDVHGPSLLTSRDFNWGVKDWKGRPWEEAVVYELHPGTFSPEGGSGGIRRKLDYLAEVGFTAIEIMPVAQFSGNRG
WGYDGVLPYCPHSAYGGVAGLKELVDAAHERGLMMILDVVYNHFGPDGNYLSLYAPDFFDPSRDTPWGPAIRFEEPAVRA
FFLDNPIYWLEEFRFDGLRFDAIDQIKDRSETPILQEIARAIRSRYPDRHIHLMTEDERNIVELHPRDDANRPILFTAEW
NDDFHHAAHCVATGEDTGYYAAFADDPAGHLARALAEGFCYQGEPYAPREGKPRGVPSAGQPPAAFVDFLQNHDQIGNRA
FGERLTALADADTVELLTAVLLLNPQIPLAFMGEEFGETNPFLFFTDFHGDLAKAVREGRRHEFKDFGHFSGEQAEQIPD
PNALSTFEASMLDWDRVETEAGRKRLDLFRRLLQVRKVHLLPHLSDMTSMQGHSTRLGEKALSVRWRMSDRVLVMAANFG
TAAVDTADGFVGCKAIYESRKGVEAALLQGELPERSVAVLITEEAGT
>Mature_606_residues
THTTFQTRWGAQLQDDDTALFRLWAPAADQLRLRFGGGEERAMERGQGGWFELEIGGLAAGTPYQFVLPDGTAVPDPASR
AQAGDVHGPSLLTSRDFNWGVKDWKGRPWEEAVVYELHPGTFSPEGGSGGIRRKLDYLAEVGFTAIEIMPVAQFSGNRGW
GYDGVLPYCPHSAYGGVAGLKELVDAAHERGLMMILDVVYNHFGPDGNYLSLYAPDFFDPSRDTPWGPAIRFEEPAVRAF
FLDNPIYWLEEFRFDGLRFDAIDQIKDRSETPILQEIARAIRSRYPDRHIHLMTEDERNIVELHPRDDANRPILFTAEWN
DDFHHAAHCVATGEDTGYYAAFADDPAGHLARALAEGFCYQGEPYAPREGKPRGVPSAGQPPAAFVDFLQNHDQIGNRAF
GERLTALADADTVELLTAVLLLNPQIPLAFMGEEFGETNPFLFFTDFHGDLAKAVREGRRHEFKDFGHFSGEQAEQIPDP
NALSTFEASMLDWDRVETEAGRKRLDLFRRLLQVRKVHLLPHLSDMTSMQGHSTRLGEKALSVRWRMSDRVLVMAANFGT
AAVDTADGFVGCKAIYESRKGVEAALLQGELPERSVAVLITEEAGT

Specific function: Hydrolyzes The Alpha-1,6-Glucosidic Linkages In Glycogen Which Has First Been Partially Depolymerized By Phosphorylase. Shows Only Very Little Activity With Native Glycogen. [C]

COG id: COG0296

COG function: function code G; 1,4-alpha-glucan branching enzyme

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI189458812, Length=168, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI2367229, Length=268, Percent_Identity=28.7313432835821, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789839, Length=268, Percent_Identity=25.3731343283582, Blast_Score=66, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI32564391, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554896, Length=306, Percent_Identity=25.1633986928105, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320826, Length=298, Percent_Identity=25.503355704698, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573410, Length=299, Percent_Identity=23.4113712374582, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004193
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR015156
- InterPro:   IPR012768 [H]

Pfam domain/function: PF09071 Alpha-amyl_C; PF00128 Alpha-amylase; PF02922 CBM_48 [H]

EC number: =3.2.1.141 [H]

Molecular weight: Translated: 67644; Mature: 67513

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTTFQTRWGAQLQDDDTALFRLWAPAADQLRLRFGGGEERAMERGQGGWFELEIGGLA
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHCCCCCEEEEEECCEE
AGTPYQFVLPDGTAVPDPASRAQAGDVHGPSLLTSRDFNWGVKDWKGRPWEEAVVYELHP
CCCCEEEECCCCCCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECC
GTFSPEGGSGGIRRKLDYLAEVGFTAIEIMPVAQFSGNRGWGYDGVLPYCPHSAYGGVAG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHEECCCCCCCCCCCCCCCCCCCCCCHHH
LKELVDAAHERGLMMILDVVYNHFGPDGNYLSLYAPDFFDPSRDTPWGPAIRFEEPAVRA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCEEE
FFLDNPIYWLEEFRFDGLRFDAIDQIKDRSETPILQEIARAIRSRYPDRHIHLMTEDERN
EEECCCHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
IVELHPRDDANRPILFTAEWNDDFHHAAHCVATGEDTGYYAAFADDPAGHLARALAEGFC
EEEECCCCCCCCCEEEEEECCCCHHHHEEEEECCCCCCEEEEECCCCHHHHHHHHHHCCC
YQGEPYAPREGKPRGVPSAGQPPAAFVDFLQNHDQIGNRAFGERLTALADADTVELLTAV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
LLLNPQIPLAFMGEEFGETNPFLFFTDFHGDLAKAVREGRRHEFKDFGHFSGEQAEQIPD
HHHCCCCCEEECCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
PNALSTFEASMLDWDRVETEAGRKRLDLFRRLLQVRKVHLLPHLSDMTSMQGHSTRLGEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHH
ALSVRWRMSDRVLVMAANFGTAAVDTADGFVGCKAIYESRKGVEAALLQGELPERSVAVL
HHEEEEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEE
ITEEAGT
EECCCCC
>Mature Secondary Structure 
THTTFQTRWGAQLQDDDTALFRLWAPAADQLRLRFGGGEERAMERGQGGWFELEIGGLA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHCCCCCEEEEEECCEE
AGTPYQFVLPDGTAVPDPASRAQAGDVHGPSLLTSRDFNWGVKDWKGRPWEEAVVYELHP
CCCCEEEECCCCCCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECC
GTFSPEGGSGGIRRKLDYLAEVGFTAIEIMPVAQFSGNRGWGYDGVLPYCPHSAYGGVAG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEHEECCCCCCCCCCCCCCCCCCCCCCHHH
LKELVDAAHERGLMMILDVVYNHFGPDGNYLSLYAPDFFDPSRDTPWGPAIRFEEPAVRA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCEEE
FFLDNPIYWLEEFRFDGLRFDAIDQIKDRSETPILQEIARAIRSRYPDRHIHLMTEDERN
EEECCCHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
IVELHPRDDANRPILFTAEWNDDFHHAAHCVATGEDTGYYAAFADDPAGHLARALAEGFC
EEEECCCCCCCCCEEEEEECCCCHHHHEEEEECCCCCCEEEEECCCCHHHHHHHHHHCCC
YQGEPYAPREGKPRGVPSAGQPPAAFVDFLQNHDQIGNRAFGERLTALADADTVELLTAV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
LLLNPQIPLAFMGEEFGETNPFLFFTDFHGDLAKAVREGRRHEFKDFGHFSGEQAEQIPD
HHHCCCCCEEECCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
PNALSTFEASMLDWDRVETEAGRKRLDLFRRLLQVRKVHLLPHLSDMTSMQGHSTRLGEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHH
ALSVRWRMSDRVLVMAANFGTAAVDTADGFVGCKAIYESRKGVEAALLQGELPERSVAVL
HHEEEEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCEEEE
ITEEAGT
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]