Click here to switch to the map view.

The map label for this gene is gsiD [H]

Identifier: 110634970

GI number: 110634970

Start: 2845923

End: 2846774

Strand: Reverse

Name: gsiD [H]

Synonym: Meso_2636

Alternate gene names: 110634970

Gene position: 2846774-2845923 (Counterclockwise)

Preceding gene: 110634971

Following gene: 110634969

Centisome position: 64.52

GC content: 62.09

Gene sequence:

>852_bases
ATGCAGCGTCTGACCAGGTTCGCTGGGAAGATCGGGACTTCGGGCACCTTCGGCTTCGCCGGAGTAGCGATCCTGCTTCT
GACGGCTATCATATCGCCGGCCTTCACGCCCCACGATCCGAATGCGATCGATGTGCTCCACCGCATGGCGCTCCCATCCT
GGGAGCATTGGTTCGGCACCGATCATCTGGGTCGCGACCTTTTGAGCCGCCACATGGTAGGGACTTCCGTGGCGATGGCG
GTGGCACTGGGAGCGGCGTTCATCGCCTTGACCGGAGGAACCATTCTCGGGCTCCTGGCCGCCTATATGTCCGGCTATGT
CGAGCGGGCGATATTGATCGCCTTCGATGCCATCGCCTCCTATCCCAGCGTCATCCTCGCCCTCGCCGCCGTGGCCGTTC
TGGGCTCCTCGATGGTTACGATCTCGGCTGTGATTGGCTTTGCGCTGATCCCACACTTCGGGCGCGTTGCCCGCGCCCAA
ACCCTAGCGATACGCCGCGCGCCTTTTGTCGAGGCGGAGATCGTGGTCGGCGCATCGGAGGCGCGGATCCTGATGCACCA
CATCCTGCCCAATATTGCAGGCCCGCTGATCGTGCTCGCTTCCTTGGATATTCCTATCATCATCGCGATCGAGGCCGGCA
TGTCCTTCCTGGGCCTGGGCATCCGCCCGCCAAGCGCCAGTTGGGGCGTGCTGCTCCAGGACGGCTATCAAAACCTGTCG
GAGTCCATGTCTCCGGTTCTGATCTCGTGTGGAGTGCTGGCCGTCGCCACCCTGGCATTCACCTTGTTGGGCGAGACCTT
GCGTAAGCTGGGAGACCCGCGCGCAGTAAGTAATAGTGCCCGATATGCATAA

Upstream 100 bases:

>100_bases
GGAGCATTTTTGTCGTCGTGGTCCTGTTCGTCTTCATCAACTTCATAACCGAATATGTCTTCCGGATCGCCGATCCCCGG
TTCAGCAAGGATGCCGCCTG

Downstream 100 bases:

>100_bases
TCCGTTGCTGTCGATAAAGGACGTGCGCCTCAGCGTACGCGGGAACGGGGAGCACGAGATTCTCTGCGGCGTGGATCTGA
ATCTCCCCAGGGGGAAAATC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MQRLTRFAGKIGTSGTFGFAGVAILLLTAIISPAFTPHDPNAIDVLHRMALPSWEHWFGTDHLGRDLLSRHMVGTSVAMA
VALGAAFIALTGGTILGLLAAYMSGYVERAILIAFDAIASYPSVILALAAVAVLGSSMVTISAVIGFALIPHFGRVARAQ
TLAIRRAPFVEAEIVVGASEARILMHHILPNIAGPLIVLASLDIPIIIAIEAGMSFLGLGIRPPSASWGVLLQDGYQNLS
ESMSPVLISCGVLAVATLAFTLLGETLRKLGDPRAVSNSARYA

Sequences:

>Translated_283_residues
MQRLTRFAGKIGTSGTFGFAGVAILLLTAIISPAFTPHDPNAIDVLHRMALPSWEHWFGTDHLGRDLLSRHMVGTSVAMA
VALGAAFIALTGGTILGLLAAYMSGYVERAILIAFDAIASYPSVILALAAVAVLGSSMVTISAVIGFALIPHFGRVARAQ
TLAIRRAPFVEAEIVVGASEARILMHHILPNIAGPLIVLASLDIPIIIAIEAGMSFLGLGIRPPSASWGVLLQDGYQNLS
ESMSPVLISCGVLAVATLAFTLLGETLRKLGDPRAVSNSARYA
>Mature_283_residues
MQRLTRFAGKIGTSGTFGFAGVAILLLTAIISPAFTPHDPNAIDVLHRMALPSWEHWFGTDHLGRDLLSRHMVGTSVAMA
VALGAAFIALTGGTILGLLAAYMSGYVERAILIAFDAIASYPSVILALAAVAVLGSSMVTISAVIGFALIPHFGRVARAQ
TLAIRRAPFVEAEIVVGASEARILMHHILPNIAGPLIVLASLDIPIIIAIEAGMSFLGLGIRPPSASWGVLLQDGYQNLS
ESMSPVLISCGVLAVATLAFTLLGETLRKLGDPRAVSNSARYA

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=254, Percent_Identity=35.8267716535433, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787760, Length=281, Percent_Identity=37.0106761565836, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1789889, Length=250, Percent_Identity=34, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787498, Length=250, Percent_Identity=34.4, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789964, Length=255, Percent_Identity=34.5098039215686, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787549, Length=265, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788505, Length=227, Percent_Identity=27.3127753303965, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29616; Mature: 29616

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLTRFAGKIGTSGTFGFAGVAILLLTAIISPAFTPHDPNAIDVLHRMALPSWEHWFGT
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHCCC
DHLGRDLLSRHMVGTSVAMAVALGAAFIALTGGTILGLLAAYMSGYVERAILIAFDAIAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPSVILALAAVAVLGSSMVTISAVIGFALIPHFGRVARAQTLAIRRAPFVEAEIVVGASE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHH
ARILMHHILPNIAGPLIVLASLDIPIIIAIEAGMSFLGLGIRPPSASWGVLLQDGYQNLS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHH
ESMSPVLISCGVLAVATLAFTLLGETLRKLGDPRAVSNSARYA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQRLTRFAGKIGTSGTFGFAGVAILLLTAIISPAFTPHDPNAIDVLHRMALPSWEHWFGT
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHCCC
DHLGRDLLSRHMVGTSVAMAVALGAAFIALTGGTILGLLAAYMSGYVERAILIAFDAIAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPSVILALAAVAVLGSSMVTISAVIGFALIPHFGRVARAQTLAIRRAPFVEAEIVVGASE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHH
ARILMHHILPNIAGPLIVLASLDIPIIIAIEAGMSFLGLGIRPPSASWGVLLQDGYQNLS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHH
ESMSPVLISCGVLAVATLAFTLLGETLRKLGDPRAVSNSARYA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]