Click here to switch to the map view.

The map label for this gene is nac [H]

Identifier: 110634890

GI number: 110634890

Start: 2731754

End: 2733613

Strand: Direct

Name: nac [H]

Synonym: Meso_2549

Alternate gene names: 110634890

Gene position: 2731754-2733613 (Clockwise)

Preceding gene: 110634879

Following gene: 110634892

Centisome position: 61.91

GC content: 60.22

Gene sequence:

>1860_bases
ATGAATCTTAGGGCCCTCTGGTACTTCCTGTCCGCTTTTTCGGGAGCAGGCATCAACAACGGGGCGAAACGGCTGGGAAT
TTCGCAAGCCACGCTAAGCGCTGCGATCACCGGCCTTGAGGAACTGCTGGGCGCAGCCCTGTTCGACCGCACGCCGGCCG
GGCTGCAGCCTACCCCGATGGCAATGCGGTTCAGCGCTTTCGCGAGCGCGATCACGACCGATGTTGAAATGGCCTTCCTG
GACATCGCAGCGAATTCCAGCGGCGAGATCGAGCCTGCCCCCGTAATTTCCTATGACGTCCCACTCTGCTCTGTTGCCGA
CTGGGCCCTTCTGCGCGGCATGCTGGCATCCATTCCGCTCGGGGGCGCGAGGGGAATAAGGATTGCTTCGGATTTGACTG
AAAGAGACGTTCCGAGGCCTGGCTCGGTGTCTGTCTCCTATGGGCTCGCCAGGCCCGGATCGGAGGAAATGGACGGACCG
GGAGAGATTATCCCCGACAGCTGGTGCCTGGTCACGACCGGGTCCCGCTTTTCGGAGGAGCAGCCAATTGCATGGGACGA
TATCATCAAGGCACCCCTGCTGATGGCCCGAGTGTCTGGCAATCCCGAGCAGCGGCTGTTTCGGCAGGCCCGGCCGCCCG
AACTTATCAGGTTGGACCGCTTGAGGTCATATACCAATCTTCTTTCGCAGGGTGACACCTCCCTGCTGCTGCCGCGATCC
TGCCTGCTGGACGGCTTCGTCTCCAGCGAGCTCCGCATGCTGAAAATAGAAGGTGCCCCGCTGCAGCCGGCAATCCAGGT
GCAATGCCATGATGGTTCGCCCTTGCCCGTGAAGCGCCTCGCCGCAGAAATAGCAAGGGAGCTTTCAGCCACTTTGCCGG
CGACCAATTATCGCCAGACACGGCTGCAAGTGCTTGAACGCGGTTTGGAAATCCAAGCCTTCCGGAGCTTTACAGAAACC
ATCAGGACCGGAAGCACGACCAAAGCCGCCAACCAGCTCCGCATTGTCCAGCCTGCACTGTCGCGCCAGATCCGGAAGCT
GGAAAACGCAACGGGACAGCAGCTTTTCATCCGCTCCGAGCATGGCATGACGCCTACCGCCGCGAGCCGCCGACTGCATC
TGCTGACCAAGACGGTTATGGCCGATTACGCGACCGGACTTGAGCAGATGAAGGGCAGGAAAAGCATCGGCGAATCCGCC
GCCGCCCGGGTCCGCTTCGGCATTATCCCGGCTGCGGATTCGAGCAGCCTCATAGCTCAAGGCGTCGCGAAAACCATTGC
GCAATGGAAGATCGCATTTCCAGAGGCTGAAGTGATGATGGCGGAGGGCTATTCCAGCGAGCTTCTTCGCTGGCTGCGTA
CCCATCTGATCGACTTTGCCATTATCGATACCCATGAAAGAGAACCGGGGCTGGTCGTCAATCCGATCTTCACGGAGCCA
ATCAGCTTGGTCTTCGCGAAAGGCTCGATCTGGGACACCGGCGAGCCGGAGATTGCGATGTCGAAATTGGACCCAAGGCG
CCTATGCCTTCCTTCTAAAGAATTTGGTCTTCGGGCCCATTTCGACCTGGCAATGTCCGAGATTGACAAGGGTGTTTCGC
CTGGTCTCCAAATAGACAGCCTGGCGGTTTGCCTGGGCCTCGTGACGACGGCAGAATGGGCAACGCTTCTGCCTTTCAGC
GCCGTGCATCATCTTTTGGCAGCGCGGCAATTGAGCTACCGCGTTCTGGTCCAGCCGCAAGTGGATCGGCGCATCTGTTC
TGTGCGCAGCCTGCGCGCACCGCAGACGACCGCTTCGGCGGCCCTGATGCGTGCGCTGGAGGTCTCCCTCGCGCAGCTTC
TGCACCAGGATGGCCGGTGA

Upstream 100 bases:

>100_bases
CCCGCCGATCTTTCTGGTCTAGCTACCTCCTATGCTGGGAGCCTTGTTGCACTCCAATGATAGTTTTCTATAAAGGGTAT
CAATTTTTGCGAAGGCCAAA

Downstream 100 bases:

>100_bases
GCTGTTGGATTGGCGCCGTTTGCGAGAAGCCGTTGAGCAAGGGGCCACTGCAGTTGCTTTCGCTCAATCGCGAGCGAGTC
TCAATGTTAAGGCCTGCAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen assimilation control protein [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MNLRALWYFLSAFSGAGINNGAKRLGISQATLSAAITGLEELLGAALFDRTPAGLQPTPMAMRFSAFASAITTDVEMAFL
DIAANSSGEIEPAPVISYDVPLCSVADWALLRGMLASIPLGGARGIRIASDLTERDVPRPGSVSVSYGLARPGSEEMDGP
GEIIPDSWCLVTTGSRFSEEQPIAWDDIIKAPLLMARVSGNPEQRLFRQARPPELIRLDRLRSYTNLLSQGDTSLLLPRS
CLLDGFVSSELRMLKIEGAPLQPAIQVQCHDGSPLPVKRLAAEIARELSATLPATNYRQTRLQVLERGLEIQAFRSFTET
IRTGSTTKAANQLRIVQPALSRQIRKLENATGQQLFIRSEHGMTPTAASRRLHLLTKTVMADYATGLEQMKGRKSIGESA
AARVRFGIIPAADSSSLIAQGVAKTIAQWKIAFPEAEVMMAEGYSSELLRWLRTHLIDFAIIDTHEREPGLVVNPIFTEP
ISLVFAKGSIWDTGEPEIAMSKLDPRRLCLPSKEFGLRAHFDLAMSEIDKGVSPGLQIDSLAVCLGLVTTAEWATLLPFS
AVHHLLAARQLSYRVLVQPQVDRRICSVRSLRAPQTTASAALMRALEVSLAQLLHQDGR

Sequences:

>Translated_619_residues
MNLRALWYFLSAFSGAGINNGAKRLGISQATLSAAITGLEELLGAALFDRTPAGLQPTPMAMRFSAFASAITTDVEMAFL
DIAANSSGEIEPAPVISYDVPLCSVADWALLRGMLASIPLGGARGIRIASDLTERDVPRPGSVSVSYGLARPGSEEMDGP
GEIIPDSWCLVTTGSRFSEEQPIAWDDIIKAPLLMARVSGNPEQRLFRQARPPELIRLDRLRSYTNLLSQGDTSLLLPRS
CLLDGFVSSELRMLKIEGAPLQPAIQVQCHDGSPLPVKRLAAEIARELSATLPATNYRQTRLQVLERGLEIQAFRSFTET
IRTGSTTKAANQLRIVQPALSRQIRKLENATGQQLFIRSEHGMTPTAASRRLHLLTKTVMADYATGLEQMKGRKSIGESA
AARVRFGIIPAADSSSLIAQGVAKTIAQWKIAFPEAEVMMAEGYSSELLRWLRTHLIDFAIIDTHEREPGLVVNPIFTEP
ISLVFAKGSIWDTGEPEIAMSKLDPRRLCLPSKEFGLRAHFDLAMSEIDKGVSPGLQIDSLAVCLGLVTTAEWATLLPFS
AVHHLLAARQLSYRVLVQPQVDRRICSVRSLRAPQTTASAALMRALEVSLAQLLHQDGR
>Mature_619_residues
MNLRALWYFLSAFSGAGINNGAKRLGISQATLSAAITGLEELLGAALFDRTPAGLQPTPMAMRFSAFASAITTDVEMAFL
DIAANSSGEIEPAPVISYDVPLCSVADWALLRGMLASIPLGGARGIRIASDLTERDVPRPGSVSVSYGLARPGSEEMDGP
GEIIPDSWCLVTTGSRFSEEQPIAWDDIIKAPLLMARVSGNPEQRLFRQARPPELIRLDRLRSYTNLLSQGDTSLLLPRS
CLLDGFVSSELRMLKIEGAPLQPAIQVQCHDGSPLPVKRLAAEIARELSATLPATNYRQTRLQVLERGLEIQAFRSFTET
IRTGSTTKAANQLRIVQPALSRQIRKLENATGQQLFIRSEHGMTPTAASRRLHLLTKTVMADYATGLEQMKGRKSIGESA
AARVRFGIIPAADSSSLIAQGVAKTIAQWKIAFPEAEVMMAEGYSSELLRWLRTHLIDFAIIDTHEREPGLVVNPIFTEP
ISLVFAKGSIWDTGEPEIAMSKLDPRRLCLPSKEFGLRAHFDLAMSEIDKGVSPGLQIDSLAVCLGLVTTAEWATLLPFS
AVHHLLAARQLSYRVLVQPQVDRRICSVRSLRAPQTTASAALMRALEVSLAQLLHQDGR

Specific function: Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=259, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789506, Length=250, Percent_Identity=26.8, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI157672245, Length=292, Percent_Identity=26.3698630136986, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 67446; Mature: 67446

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRALWYFLSAFSGAGINNGAKRLGISQATLSAAITGLEELLGAALFDRTPAGLQPTPM
CCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
AMRFSAFASAITTDVEMAFLDIAANSSGEIEPAPVISYDVPLCSVADWALLRGMLASIPL
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCC
GGARGIRIASDLTERDVPRPGSVSVSYGLARPGSEEMDGPGEIIPDSWCLVTTGSRFSEE
CCCCCCEEHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
QPIAWDDIIKAPLLMARVSGNPEQRLFRQARPPELIRLDRLRSYTNLLSQGDTSLLLPRS
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEECCHH
CLLDGFVSSELRMLKIEGAPLQPAIQVQCHDGSPLPVKRLAAEIARELSATLPATNYRQT
HHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
RLQVLERGLEIQAFRSFTETIRTGSTTKAANQLRIVQPALSRQIRKLENATGQQLFIRSE
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHEEHHHHHHHHHHHHHCCCCCEEEEECC
HGMTPTAASRRLHLLTKTVMADYATGLEQMKGRKSIGESAAARVRFGIIPAADSSSLIAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEEEECCCCHHHHHH
GVAKTIAQWKIAFPEAEVMMAEGYSSELLRWLRTHLIDFAIIDTHEREPGLVVNPIFTEP
HHHHHHHHHEEECCCHHEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCEEECCCCCCC
ISLVFAKGSIWDTGEPEIAMSKLDPRRLCLPSKEFGLRAHFDLAMSEIDKGVSPGLQIDS
EEEEEECCCCCCCCCCCEECCCCCCHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCHHH
LAVCLGLVTTAEWATLLPFSAVHHLLAARQLSYRVLVQPQVDRRICSVRSLRAPQTTASA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCHHHHH
ALMRALEVSLAQLLHQDGR
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLRALWYFLSAFSGAGINNGAKRLGISQATLSAAITGLEELLGAALFDRTPAGLQPTPM
CCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
AMRFSAFASAITTDVEMAFLDIAANSSGEIEPAPVISYDVPLCSVADWALLRGMLASIPL
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCC
GGARGIRIASDLTERDVPRPGSVSVSYGLARPGSEEMDGPGEIIPDSWCLVTTGSRFSEE
CCCCCCEEHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
QPIAWDDIIKAPLLMARVSGNPEQRLFRQARPPELIRLDRLRSYTNLLSQGDTSLLLPRS
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEECCHH
CLLDGFVSSELRMLKIEGAPLQPAIQVQCHDGSPLPVKRLAAEIARELSATLPATNYRQT
HHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
RLQVLERGLEIQAFRSFTETIRTGSTTKAANQLRIVQPALSRQIRKLENATGQQLFIRSE
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHEEHHHHHHHHHHHHHCCCCCEEEEECC
HGMTPTAASRRLHLLTKTVMADYATGLEQMKGRKSIGESAAARVRFGIIPAADSSSLIAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEEEECCCCHHHHHH
GVAKTIAQWKIAFPEAEVMMAEGYSSELLRWLRTHLIDFAIIDTHEREPGLVVNPIFTEP
HHHHHHHHHEEECCCHHEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCEEECCCCCCC
ISLVFAKGSIWDTGEPEIAMSKLDPRRLCLPSKEFGLRAHFDLAMSEIDKGVSPGLQIDS
EEEEEECCCCCCCCCCCEECCCCCCHHHCCCCHHHCCCHHHHHHHHHHHCCCCCCCCHHH
LAVCLGLVTTAEWATLLPFSAVHHLLAARQLSYRVLVQPQVDRRICSVRSLRAPQTTASA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCHHHHH
ALMRALEVSLAQLLHQDGR
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]