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The map label for this gene is hipO [H]

Identifier: 110634873

GI number: 110634873

Start: 2712001

End: 2713344

Strand: Reverse

Name: hipO [H]

Synonym: Meso_2532

Alternate gene names: 110634873

Gene position: 2713344-2712001 (Counterclockwise)

Preceding gene: 110634874

Following gene: 110634862

Centisome position: 61.49

GC content: 54.76

Gene sequence:

>1344_bases
ATGAATATCAAATCAACCGCCACAAGCTTATTTCTTATTTTGCAATTTGCCGCGGGCCACGCCCTAGCGGAAACTGCAAC
ATTGGACGCTCTCATCGACCAGAAATATCCTGCGCTTGAAGCGATTTACCAGGATATTCACGCCAACCCGGAATTGGGCT
TTCATGAAACGCGGACGGCAAATCTGCTGGCGGAAGAGCTTGAAAAGCTCGGCTTTGATGTAACCGTCGGCTTTGGCGTC
GATTCCGGCCTTGTCGGCGTTTTCAAGAATGGTGACGGCCCAACCATCATGTTGCGTACGGAACTCGACGCTCTTCCCAT
GGAGGAAAAGACGGGACTTCCCTTTGCAAGCCGCGTGCAGGTACCGGCAACGCAGTGGCCAGGCAATACCGATGAATCGG
CAAAGGTCTTTGTCGCCCATAGTTGCGGCCATGATATTCACATGGCGGCATGGCTAGGAGCCGCGCAACTGTTGGTGGAT
ATGAAAGACGATTGGCGTGGCACGCTGTTGCTGATCGGCGAGCCCGCCGAAGAAATTGGCGGCGGTGCAACAGCAATGCT
CAAGGCAGGCCTGTTCGAAAAGTTTCCGAAGCCGGATTTCGGCTTTGCCATACATGTGTCTCCTGACCCTGCTGGCAAGA
TCGTCGTAAAGGACGGCCCCTTTAGCGGAAACTCCGATACCTTCGATCTGACCTTCAAAGGCCGTGGGGCACATGGTAGC
GCTCCGCACCTGTCGATTGATCCGATCGTGTTGGGTTCGCGCTTCGTCACTGATATTCAGACTATTGTGAGCCGCGAGAA
AGATCCACGCGAACCGGGGGTCATTTCGGTCGGTAGCTTCAATGCGGGAACCGCAGCCAACATCATCCCTGCCGAGGCTA
AGTTGAAGCTGACTCTACGTTCAACCTCGCCCGAGACACGCAAACTCCTGCTTGACTCCATGCAGCGCGTAGCGAAGGCT
ACAGCGCAATCCTCAGGCGCACCGGAGCCAGAATTGCAGCGTATAGGAGGCGGCGCTGTTGCAGGCGTCAACTCGACGGA
GTTGATCAGCAAACTTAAGCCGGCATTGGACAGCGCTTTCCAAAACATAGAGTACGTTCCGGAGGCTGTTAAGCCGACAC
TGGGCGTGGAGACCTATCCAGAGTTTATCGAGGCTGGTGTGCCTTCCATCTACTATAGGGTCGGCGGCAGTACACCCGAA
CAGATTGAAAAAGCCAAGCTCGAAAATAGGCCCGTACCGGCGAGCCACTCGCCGTTCTTCGCCCCGGACCCAGAGGTTAC
AATCAAAACTGGGGCAAAGCTGTTTGCAATTTCAGTGATCGAGAATGCAGGTGTGAACGAATAG

Upstream 100 bases:

>100_bases
CCTTGCGGTTCCTATGCCTGGGGGGAAGCCCCTATCGCGGCAACGTCCCAATATGTGCCGGTTAAGAGTCTTTCGGCCTC
CAACGACTGAAGGGAACCAA

Downstream 100 bases:

>100_bases
TCCCTTGATTGGGGCTTGCGGCCGGTTTCTGAGGTCATCAGATGTCTTGATGACCTCAGAATGGATGATGAGAAGGTTGC
TAGTTACTCGTCACTGACTC

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MNIKSTATSLFLILQFAAGHALAETATLDALIDQKYPALEAIYQDIHANPELGFHETRTANLLAEELEKLGFDVTVGFGV
DSGLVGVFKNGDGPTIMLRTELDALPMEEKTGLPFASRVQVPATQWPGNTDESAKVFVAHSCGHDIHMAAWLGAAQLLVD
MKDDWRGTLLLIGEPAEEIGGGATAMLKAGLFEKFPKPDFGFAIHVSPDPAGKIVVKDGPFSGNSDTFDLTFKGRGAHGS
APHLSIDPIVLGSRFVTDIQTIVSREKDPREPGVISVGSFNAGTAANIIPAEAKLKLTLRSTSPETRKLLLDSMQRVAKA
TAQSSGAPEPELQRIGGGAVAGVNSTELISKLKPALDSAFQNIEYVPEAVKPTLGVETYPEFIEAGVPSIYYRVGGSTPE
QIEKAKLENRPVPASHSPFFAPDPEVTIKTGAKLFAISVIENAGVNE

Sequences:

>Translated_447_residues
MNIKSTATSLFLILQFAAGHALAETATLDALIDQKYPALEAIYQDIHANPELGFHETRTANLLAEELEKLGFDVTVGFGV
DSGLVGVFKNGDGPTIMLRTELDALPMEEKTGLPFASRVQVPATQWPGNTDESAKVFVAHSCGHDIHMAAWLGAAQLLVD
MKDDWRGTLLLIGEPAEEIGGGATAMLKAGLFEKFPKPDFGFAIHVSPDPAGKIVVKDGPFSGNSDTFDLTFKGRGAHGS
APHLSIDPIVLGSRFVTDIQTIVSREKDPREPGVISVGSFNAGTAANIIPAEAKLKLTLRSTSPETRKLLLDSMQRVAKA
TAQSSGAPEPELQRIGGGAVAGVNSTELISKLKPALDSAFQNIEYVPEAVKPTLGVETYPEFIEAGVPSIYYRVGGSTPE
QIEKAKLENRPVPASHSPFFAPDPEVTIKTGAKLFAISVIENAGVNE
>Mature_447_residues
MNIKSTATSLFLILQFAAGHALAETATLDALIDQKYPALEAIYQDIHANPELGFHETRTANLLAEELEKLGFDVTVGFGV
DSGLVGVFKNGDGPTIMLRTELDALPMEEKTGLPFASRVQVPATQWPGNTDESAKVFVAHSCGHDIHMAAWLGAAQLLVD
MKDDWRGTLLLIGEPAEEIGGGATAMLKAGLFEKFPKPDFGFAIHVSPDPAGKIVVKDGPFSGNSDTFDLTFKGRGAHGS
APHLSIDPIVLGSRFVTDIQTIVSREKDPREPGVISVGSFNAGTAANIIPAEAKLKLTLRSTSPETRKLLLDSMQRVAKA
TAQSSGAPEPELQRIGGGAVAGVNSTELISKLKPALDSAFQNIEYVPEAVKPTLGVETYPEFIEAGVPSIYYRVGGSTPE
QIEKAKLENRPVPASHSPFFAPDPEVTIKTGAKLFAISVIENAGVNE

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=370, Percent_Identity=25.9459459459459, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 47546; Mature: 47546

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKSTATSLFLILQFAAGHALAETATLDALIDQKYPALEAIYQDIHANPELGFHETRTA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHH
NLLAEELEKLGFDVTVGFGVDSGLVGVFKNGDGPTIMLRTELDALPMEEKTGLPFASRVQ
HHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCHHCCCCCHHEEC
VPATQWPGNTDESAKVFVAHSCGHDIHMAAWLGAAQLLVDMKDDWRGTLLLIGEPAEEIG
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEECCCCCCEEEEEEECCHHHHC
GGATAMLKAGLFEKFPKPDFGFAIHVSPDPAGKIVVKDGPFSGNSDTFDLTFKGRGAHGS
CCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCC
APHLSIDPIVLGSRFVTDIQTIVSREKDPREPGVISVGSFNAGTAANIIPAEAKLKLTLR
CCCCEECCEEECCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEECCCEEEEEEEE
STSPETRKLLLDSMQRVAKATAQSSGAPEPELQRIGGGAVAGVNSTELISKLKPALDSAF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHH
QNIEYVPEAVKPTLGVETYPEFIEAGVPSIYYRVGGSTPEQIEKAKLENRPVPASHSPFF
HHHHHCHHHHCCCCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCC
APDPEVTIKTGAKLFAISVIENAGVNE
CCCCCEEEECCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MNIKSTATSLFLILQFAAGHALAETATLDALIDQKYPALEAIYQDIHANPELGFHETRTA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHH
NLLAEELEKLGFDVTVGFGVDSGLVGVFKNGDGPTIMLRTELDALPMEEKTGLPFASRVQ
HHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCHHCCCCCHHEEC
VPATQWPGNTDESAKVFVAHSCGHDIHMAAWLGAAQLLVDMKDDWRGTLLLIGEPAEEIG
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEECCCCCCEEEEEEECCHHHHC
GGATAMLKAGLFEKFPKPDFGFAIHVSPDPAGKIVVKDGPFSGNSDTFDLTFKGRGAHGS
CCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCC
APHLSIDPIVLGSRFVTDIQTIVSREKDPREPGVISVGSFNAGTAANIIPAEAKLKLTLR
CCCCEECCEEECCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEECCCEEEEEEEE
STSPETRKLLLDSMQRVAKATAQSSGAPEPELQRIGGGAVAGVNSTELISKLKPALDSAF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHH
QNIEYVPEAVKPTLGVETYPEFIEAGVPSIYYRVGGSTPEQIEKAKLENRPVPASHSPFF
HHHHHCHHHHCCCCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCC
APDPEVTIKTGAKLFAISVIENAGVNE
CCCCCEEEECCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]