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The map label for this gene is betT [C]

Identifier: 110634813

GI number: 110634813

Start: 2649789

End: 2651792

Strand: Direct

Name: betT [C]

Synonym: Meso_2472

Alternate gene names: 110634813

Gene position: 2649789-2651792 (Clockwise)

Preceding gene: 110634812

Following gene: 110634814

Centisome position: 60.05

GC content: 60.63

Gene sequence:

>2004_bases
ATGTCTAAGTTTGTAATCAATCCGCCGGTATTTTTCGGCTCAGTAGCTATTACCGCGATATTTCTCGGTGTCGGCGTTCT
TTTTCCGGGCCAAGCGGAGGCGATCTTCACCGCTGTGCAGACCTGGATTCTCGGCTCCTTTGGCTGGCTGTACCTGCTCG
CAGTTGGGATCTTCATCGGTTCGGTGATCCTCTTTGCCGCCAGCGGGTTCGGCCATCTGAAGCTGGGGCCGGACGATTCC
ACGCCCGACTTCCATTACATGTCCTGGGTGGCCATGCTCTTTGCGGCGGGCATGGGCATCGGCCTCATGTATTTCGCCGT
CGGCGAACCGATGACGCATTTCGCTGCTCCGCCCGAGGCAGAGCCACTCACCATCGCTGCCCAGCGGCAGGCCATGAGCG
TGACCTTTTTCCACTGGGGTCTCCACGCCTGGGCTATTTATGCCGTGGTGGGCCTCTCGCTTGCCTATTTCGGCTATCGC
TACAATCTTCCTCTCACCGTGCGGTCGGGCCTTTACCCGCTGCTCAAGAACCGCATCGACGGGCCGATCGGGCATGCGGT
CGACATCTTCGCAATCTGCGGCACCCTTTTTGGCATCGCGACATCACTCGGCTTCGGCGTTCTGCAGATCAATGCGGGTC
TTAGCTATCTTCTCGGCGTGCCGAACAGCGCCGCCGTTCAGCTGGTGCTTATCGCCGTAATCACCACCGTTGCGACCATC
TCCGTCGTCACCGGAGTGGATAAGGGCATCCGGCGTTTGAGCGAGCTGAACCTGATCCTCGCGGTACTGCTCATGCTCTT
CGTGCTGGCGGTCGGCCCCACGGCGCAGCTCTTGCGCGATTTCGTGCAGAATATCGGCTTCTATCTTGACACGATCGTAT
TGCGGACCTTCAACATCTATGCCTATGAGCCGCGGCCCTGGATCGACGCCTGGACGCTCTTTTACTGGGCGTGGTGGATC
TCATGGTCGCCCTTTGTCGGCATGTTCATCGCCCGCATTTCGCGCGGCCGCACCGTGCGGGAGTTCGTGATCGCCGTCCT
TTTCATTCCCGCCGGCTTCACGTTTTTCTGGATGACGGTTTTCGGCAACACCGCCCTTTTCATCGATACGACCGTCGCCA
ATGGGGCCCTGTCCACTGCGGTCACCGATGATCTTTCCGTGGCGCTGTTCCAGTTCTTCCAATATCTTCCGCTTCCAGCC
GTCACTTCCTCGCTCGCTGTCCTGCTGGTGGCGGTGTTCTTCATCACCTCCTCCGATTCCGGCTCTCTTGTCGTCGATAC
GATCGCGGCAGGCGGCGAGACGGAGACCAGCATCGCCCAGCGCGTGTTCTGGTGTGTCCTGGAAGGTCTGATCGCGGCCG
TGCTTTTGGTTGCCGGCGGGCTTGCGGCGCTGCAATCAGCCACCATCGCAACGGCACTCCCCTTCACGCTTATCATGCTT
GTGCTGATCTGGGCGCTCTTCAAGGGCATGAAGTCAGACCTGGCGCAGCGGCAGGTCGGGCATATGGCTGTCACGCCTCA
AGCCTATCCGGCGGCCGGGCTGACTTGGCAGCGCCGGCTGGGGTTGATCCTGAATGCGCCCACGGAGCAGGAGGTGGCCG
ACTATATCGCGAAGGTGGTCACGCCGGCGCTCGAAAATGTGGCGCAGGAAATGGAGAAACGGGGAAGCAAGGCGACCGTC
TCACACGAAAACGGGGAGCATTCGGTCTCGCTCACAGTTCCCGCCAGTGGGGTGCGAGATTTCGTCTATGGGGTCCAGCC
GGCGGCCCATCGTCTGCCGGCCTTCTCCGCCCTTGAAGCGGCGCAAGGGGATCTGCGTTTCGAGGCACGCACCTTCTTCA
GCGATGGCAGCCGTGGCTACGATCTTATGGGCATGACGCAGGAGCAGATCATCGCGGATGTGCTTGCGCAATTTGACCGT
TACCTGCAGCTCGTGCAATCGCCCGAGGCTTCACTGGTGATCGGCGCGCCTGAGCACGCGCCGGATATGCCTGTCCGGCA
CTGA

Upstream 100 bases:

>100_bases
CAATCCACCAACAGAAATATCGAAGCCGAACCGGCTATCTCCTGTCAACGGGAGCTTGAATTTTCTCCCTTTGGCACGCT
TTAAACTTTGAGGTGCAGCC

Downstream 100 bases:

>100_bases
GGGCACGCCGGTTGTTGGTCGCTGGAGGGCTATTTGGAGTGGATCGCGAACCGCCCTGAACTGATCTCGGCGCTAACCGG
GCTGGGCATGTTGCTTGTCT

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MSKFVINPPVFFGSVAITAIFLGVGVLFPGQAEAIFTAVQTWILGSFGWLYLLAVGIFIGSVILFAASGFGHLKLGPDDS
TPDFHYMSWVAMLFAAGMGIGLMYFAVGEPMTHFAAPPEAEPLTIAAQRQAMSVTFFHWGLHAWAIYAVVGLSLAYFGYR
YNLPLTVRSGLYPLLKNRIDGPIGHAVDIFAICGTLFGIATSLGFGVLQINAGLSYLLGVPNSAAVQLVLIAVITTVATI
SVVTGVDKGIRRLSELNLILAVLLMLFVLAVGPTAQLLRDFVQNIGFYLDTIVLRTFNIYAYEPRPWIDAWTLFYWAWWI
SWSPFVGMFIARISRGRTVREFVIAVLFIPAGFTFFWMTVFGNTALFIDTTVANGALSTAVTDDLSVALFQFFQYLPLPA
VTSSLAVLLVAVFFITSSDSGSLVVDTIAAGGETETSIAQRVFWCVLEGLIAAVLLVAGGLAALQSATIATALPFTLIML
VLIWALFKGMKSDLAQRQVGHMAVTPQAYPAAGLTWQRRLGLILNAPTEQEVADYIAKVVTPALENVAQEMEKRGSKATV
SHENGEHSVSLTVPASGVRDFVYGVQPAAHRLPAFSALEAAQGDLRFEARTFFSDGSRGYDLMGMTQEQIIADVLAQFDR
YLQLVQSPEASLVIGAPEHAPDMPVRH

Sequences:

>Translated_667_residues
MSKFVINPPVFFGSVAITAIFLGVGVLFPGQAEAIFTAVQTWILGSFGWLYLLAVGIFIGSVILFAASGFGHLKLGPDDS
TPDFHYMSWVAMLFAAGMGIGLMYFAVGEPMTHFAAPPEAEPLTIAAQRQAMSVTFFHWGLHAWAIYAVVGLSLAYFGYR
YNLPLTVRSGLYPLLKNRIDGPIGHAVDIFAICGTLFGIATSLGFGVLQINAGLSYLLGVPNSAAVQLVLIAVITTVATI
SVVTGVDKGIRRLSELNLILAVLLMLFVLAVGPTAQLLRDFVQNIGFYLDTIVLRTFNIYAYEPRPWIDAWTLFYWAWWI
SWSPFVGMFIARISRGRTVREFVIAVLFIPAGFTFFWMTVFGNTALFIDTTVANGALSTAVTDDLSVALFQFFQYLPLPA
VTSSLAVLLVAVFFITSSDSGSLVVDTIAAGGETETSIAQRVFWCVLEGLIAAVLLVAGGLAALQSATIATALPFTLIML
VLIWALFKGMKSDLAQRQVGHMAVTPQAYPAAGLTWQRRLGLILNAPTEQEVADYIAKVVTPALENVAQEMEKRGSKATV
SHENGEHSVSLTVPASGVRDFVYGVQPAAHRLPAFSALEAAQGDLRFEARTFFSDGSRGYDLMGMTQEQIIADVLAQFDR
YLQLVQSPEASLVIGAPEHAPDMPVRH
>Mature_666_residues
SKFVINPPVFFGSVAITAIFLGVGVLFPGQAEAIFTAVQTWILGSFGWLYLLAVGIFIGSVILFAASGFGHLKLGPDDST
PDFHYMSWVAMLFAAGMGIGLMYFAVGEPMTHFAAPPEAEPLTIAAQRQAMSVTFFHWGLHAWAIYAVVGLSLAYFGYRY
NLPLTVRSGLYPLLKNRIDGPIGHAVDIFAICGTLFGIATSLGFGVLQINAGLSYLLGVPNSAAVQLVLIAVITTVATIS
VVTGVDKGIRRLSELNLILAVLLMLFVLAVGPTAQLLRDFVQNIGFYLDTIVLRTFNIYAYEPRPWIDAWTLFYWAWWIS
WSPFVGMFIARISRGRTVREFVIAVLFIPAGFTFFWMTVFGNTALFIDTTVANGALSTAVTDDLSVALFQFFQYLPLPAV
TSSLAVLLVAVFFITSSDSGSLVVDTIAAGGETETSIAQRVFWCVLEGLIAAVLLVAGGLAALQSATIATALPFTLIMLV
LIWALFKGMKSDLAQRQVGHMAVTPQAYPAAGLTWQRRLGLILNAPTEQEVADYIAKVVTPALENVAQEMEKRGSKATVS
HENGEHSVSLTVPASGVRDFVYGVQPAAHRLPAFSALEAAQGDLRFEARTFFSDGSRGYDLMGMTQEQIIADVLAQFDRY
LQLVQSPEASLVIGAPEHAPDMPVRH

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=673, Percent_Identity=40.8618127786033, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1788102, Length=462, Percent_Identity=29.8701298701299, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1786224, Length=498, Percent_Identity=26.5060240963855, Blast_Score=169, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 72229; Mature: 72098

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFVINPPVFFGSVAITAIFLGVGVLFPGQAEAIFTAVQTWILGSFGWLYLLAVGIFIG
CCCEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVILFAASGFGHLKLGPDDSTPDFHYMSWVAMLFAAGMGIGLMYFAVGEPMTHFAAPPEA
HHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
EPLTIAAQRQAMSVTFFHWGLHAWAIYAVVGLSLAYFGYRYNLPLTVRSGLYPLLKNRID
CCEEEEEHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECCCCHHHHHHHCC
GPIGHAVDIFAICGTLFGIATSLGFGVLQINAGLSYLLGVPNSAAVQLVLIAVITTVATI
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
SVVTGVDKGIRRLSELNLILAVLLMLFVLAVGPTAQLLRDFVQNIGFYLDTIVLRTFNIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
AYEPRPWIDAWTLFYWAWWISWSPFVGMFIARISRGRTVREFVIAVLFIPAGFTFFWMTV
EECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
FGNTALFIDTTVANGALSTAVTDDLSVALFQFFQYLPLPAVTSSLAVLLVAVFFITSSDS
HCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
GSLVVDTIAAGGETETSIAQRVFWCVLEGLIAAVLLVAGGLAALQSATIATALPFTLIML
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VLIWALFKGMKSDLAQRQVGHMAVTPQAYPAAGLTWQRRLGLILNAPTEQEVADYIAKVV
HHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHCCEEECCCCHHHHHHHHHHHH
TPALENVAQEMEKRGSKATVSHENGEHSVSLTVPASGVRDFVYGVQPAAHRLPAFSALEA
HHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHHCCCHHHHHCCHHHHHHH
AQGDLRFEARTFFSDGSRGYDLMGMTQEQIIADVLAQFDRYLQLVQSPEASLVIGAPEHA
HCCCCEEEHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PDMPVRH
CCCCCCC
>Mature Secondary Structure 
SKFVINPPVFFGSVAITAIFLGVGVLFPGQAEAIFTAVQTWILGSFGWLYLLAVGIFIG
CCEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVILFAASGFGHLKLGPDDSTPDFHYMSWVAMLFAAGMGIGLMYFAVGEPMTHFAAPPEA
HHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
EPLTIAAQRQAMSVTFFHWGLHAWAIYAVVGLSLAYFGYRYNLPLTVRSGLYPLLKNRID
CCEEEEEHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECCCCHHHHHHHCC
GPIGHAVDIFAICGTLFGIATSLGFGVLQINAGLSYLLGVPNSAAVQLVLIAVITTVATI
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHHH
SVVTGVDKGIRRLSELNLILAVLLMLFVLAVGPTAQLLRDFVQNIGFYLDTIVLRTFNIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
AYEPRPWIDAWTLFYWAWWISWSPFVGMFIARISRGRTVREFVIAVLFIPAGFTFFWMTV
EECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHH
FGNTALFIDTTVANGALSTAVTDDLSVALFQFFQYLPLPAVTSSLAVLLVAVFFITSSDS
HCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
GSLVVDTIAAGGETETSIAQRVFWCVLEGLIAAVLLVAGGLAALQSATIATALPFTLIML
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VLIWALFKGMKSDLAQRQVGHMAVTPQAYPAAGLTWQRRLGLILNAPTEQEVADYIAKVV
HHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHCCEEECCCCHHHHHHHHHHHH
TPALENVAQEMEKRGSKATVSHENGEHSVSLTVPASGVRDFVYGVQPAAHRLPAFSALEA
HHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHHCCCHHHHHCCHHHHHHH
AQGDLRFEARTFFSDGSRGYDLMGMTQEQIIADVLAQFDRYLQLVQSPEASLVIGAPEHA
HCCCCEEEHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PDMPVRH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]