Click here to switch to the map view.

The map label for this gene is ygjG [C]

Identifier: 110634757

GI number: 110634757

Start: 2587845

End: 2589218

Strand: Reverse

Name: ygjG [C]

Synonym: Meso_2416

Alternate gene names: 110634757

Gene position: 2589218-2587845 (Counterclockwise)

Preceding gene: 110634758

Following gene: 110634751

Centisome position: 58.68

GC content: 62.45

Gene sequence:

>1374_bases
ATGACCGACCGCTCGAACGAACTCAACGCCTGGGATCGCGACCATTTCTTCCATCCCTCGACCCATATGGGCACGCATGC
GCGTGGTGAATCGCCCAACCGCGTCGTCGCCGGTGGCGAGGGCGTCTACATTACAGACGTGAATGGCCGCACGAGCCTCG
ACGCCTTCGCTGGCCTCTACTGCGTCAATGTCGGTTATGGCCGCCAGAAGATCGCCGACGCGATCGCCGAACAGGCCAGG
AATCTCGCCTATTACCACGCCTATGTCGGCCACGGCACGGACGCCTCCATCCGGCTCGCCAAGATGATCATCGATCGTGC
GCCGCAGGGCATGAGCCGCGTCTATTTCGGCCTGTCGGGCTCGGATGCCAACGAGACCAACATCAAGCTGATCTGGTACT
ACAACAATGTGCTCGGCCGGCCTGAGAAGAAGAAGATCATCTCGCGCTGGCGCGGCTATCACGGCTCCGGCATCATGACC
GGCTCGCTAACCGGGCTCGATCTCTTCCACAATGCCTTCGACCTGCCGCGTGCGCCGATCCTGCACACCGAGGCGCCCTA
TTATTTCCGCCGCCCTGACCGCTCCATGAGCGAGGAGCAGTTCTCGCAGTACTGCGCCGACAAACTGGAGGAGATGATTC
TGGCGGAAGGTCCGGACACGGTGGCCGCCTTCATTGGCGAGCCGATCCTCGGCACAGGAGGCATCGTGCCGCCGCCGGCC
GGCTATTGGGAAAAGATTCAGGCCGTGCTGAAGAAGTACGACGTGCTTCTCATCGCCGACGAGGTGGTGACCGGCTTTGG
CCGTCTTGGCACCATGTTCGGCTCCGACCACTACGGCATAAAGCCGGATCTCATCACCATCGCCAAGGGCCTGACCTCGG
CCTATGCCCCACTTTCGGGCGTCATTGTCTCGGACAAGGTCTGGCAGGTATTGGTCCAAGGCTCCGACAAGCTCGGCGCG
CTCGGCCATGGCTGGACCTATTCGGCGCATCCGCTCTGCGCGGCCGCCGGCGTTGCCAATCTCGAGCTGATCGATGAAAT
GAATCTGGTCGAGAATGCGGGCACGGTCGGCGCCTATTTCCGTGCAGAACTGGCGAATGCAGTGGGCAGTCACCCCAATG
TCGGCGAGGTCCGGGGCGATGGTATGCTGGCCGCCGTCGAATTCGTCGCCGATCGTGACGATCGCGTCTTTTTCGATGCG
TCGAAGAAGATCGGGCCGCAGATCGCCGCCGCACTCGCCGAACGCGGCGTGATCGGCCGCGCAATGCCTCAGGGCGACAT
TCTGGGCTTCGCCCCACCGCTGTGCCTGACGAAAGAAGAAGCGGACAAGGTTATCGCCGCGACGGCCTCTGCCGTCGATA
GCGTGTTGGGATGA

Upstream 100 bases:

>100_bases
GCATAGGGCGCGAAGGCGCCCGCCACGGGCTGGAGGCCTTCACCGATCTCAAATATCTGTGCCTCGACGCAGCCTGAAAA
AAAGGAAGCAGGAATCCGCC

Downstream 100 bases:

>100_bases
CTTCAAGCGAGCTGTCGGCTGCTTGCCGTAAGCTCGCGCTATCAAAGCCGACTTTTTCGTTAAGCGATTTGCGAGCATGG
GCTGCGGGAGATCCGGCGGC

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTDRSNELNAWDRDHFFHPSTHMGTHARGESPNRVVAGGEGVYITDVNGRTSLDAFAGLYCVNVGYGRQKIADAIAEQAR
NLAYYHAYVGHGTDASIRLAKMIIDRAPQGMSRVYFGLSGSDANETNIKLIWYYNNVLGRPEKKKIISRWRGYHGSGIMT
GSLTGLDLFHNAFDLPRAPILHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMILAEGPDTVAAFIGEPILGTGGIVPPPA
GYWEKIQAVLKKYDVLLIADEVVTGFGRLGTMFGSDHYGIKPDLITIAKGLTSAYAPLSGVIVSDKVWQVLVQGSDKLGA
LGHGWTYSAHPLCAAAGVANLELIDEMNLVENAGTVGAYFRAELANAVGSHPNVGEVRGDGMLAAVEFVADRDDRVFFDA
SKKIGPQIAAALAERGVIGRAMPQGDILGFAPPLCLTKEEADKVIAATASAVDSVLG

Sequences:

>Translated_457_residues
MTDRSNELNAWDRDHFFHPSTHMGTHARGESPNRVVAGGEGVYITDVNGRTSLDAFAGLYCVNVGYGRQKIADAIAEQAR
NLAYYHAYVGHGTDASIRLAKMIIDRAPQGMSRVYFGLSGSDANETNIKLIWYYNNVLGRPEKKKIISRWRGYHGSGIMT
GSLTGLDLFHNAFDLPRAPILHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMILAEGPDTVAAFIGEPILGTGGIVPPPA
GYWEKIQAVLKKYDVLLIADEVVTGFGRLGTMFGSDHYGIKPDLITIAKGLTSAYAPLSGVIVSDKVWQVLVQGSDKLGA
LGHGWTYSAHPLCAAAGVANLELIDEMNLVENAGTVGAYFRAELANAVGSHPNVGEVRGDGMLAAVEFVADRDDRVFFDA
SKKIGPQIAAALAERGVIGRAMPQGDILGFAPPLCLTKEEADKVIAATASAVDSVLG
>Mature_456_residues
TDRSNELNAWDRDHFFHPSTHMGTHARGESPNRVVAGGEGVYITDVNGRTSLDAFAGLYCVNVGYGRQKIADAIAEQARN
LAYYHAYVGHGTDASIRLAKMIIDRAPQGMSRVYFGLSGSDANETNIKLIWYYNNVLGRPEKKKIISRWRGYHGSGIMTG
SLTGLDLFHNAFDLPRAPILHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMILAEGPDTVAAFIGEPILGTGGIVPPPAG
YWEKIQAVLKKYDVLLIADEVVTGFGRLGTMFGSDHYGIKPDLITIAKGLTSAYAPLSGVIVSDKVWQVLVQGSDKLGAL
GHGWTYSAHPLCAAAGVANLELIDEMNLVENAGTVGAYFRAELANAVGSHPNVGEVRGDGMLAAVEFVADRDDRVFFDAS
KKIGPQIAAALAERGVIGRAMPQGDILGFAPPLCLTKEEADKVIAATASAVDSVLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=27.2727272727273, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4557809, Length=446, Percent_Identity=27.5784753363229, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI37574042, Length=407, Percent_Identity=26.7813267813268, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI226442705, Length=409, Percent_Identity=27.6283618581907, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI226442709, Length=356, Percent_Identity=27.5280898876405, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI284507298, Length=226, Percent_Identity=33.1858407079646, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=24.7663551401869, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI188536080, Length=288, Percent_Identity=24.3055555555556, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI38679950, Length=288, Percent_Identity=24.3055555555556, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI38679946, Length=288, Percent_Identity=24.3055555555556, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI145693181, Length=413, Percent_Identity=26.3922518159806, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788044, Length=416, Percent_Identity=28.125, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787560, Length=419, Percent_Identity=29.3556085918854, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1789759, Length=421, Percent_Identity=27.5534441805226, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789016, Length=381, Percent_Identity=25.4593175853018, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786991, Length=447, Percent_Identity=26.3982102908277, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786349, Length=305, Percent_Identity=25.2459016393443, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=30.4054054054054, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI25144271, Length=434, Percent_Identity=27.8801843317972, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=224, Percent_Identity=34.375, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=26.6203703703704, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323470, Length=430, Percent_Identity=29.7674418604651, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=354, Percent_Identity=25.9887005649718, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=471, Percent_Identity=24.6284501061571, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=370, Percent_Identity=27.2972972972973, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574759, Length=443, Percent_Identity=28.8939051918736, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI161085790, Length=429, Percent_Identity=29.3706293706294, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21357415, Length=415, Percent_Identity=29.1566265060241, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=23.6781609195402, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281366494, Length=282, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667139, Length=282, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667143, Length=282, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 49297; Mature: 49166

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRSNELNAWDRDHFFHPSTHMGTHARGESPNRVVAGGEGVYITDVNGRTSLDAFAGLY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHCEE
CVNVGYGRQKIADAIAEQARNLAYYHAYVGHGTDASIRLAKMIIDRAPQGMSRVYFGLSG
EEECCCCHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHEEEECCC
SDANETNIKLIWYYNNVLGRPEKKKIISRWRGYHGSGIMTGSLTGLDLFHNAFDLPRAPI
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCE
LHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMILAEGPDTVAAFIGEPILGTGGIVPPPA
EECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC
GYWEKIQAVLKKYDVLLIADEVVTGFGRLGTMFGSDHYGIKPDLITIAKGLTSAYAPLSG
CHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC
VIVSDKVWQVLVQGSDKLGALGHGWTYSAHPLCAAAGVANLELIDEMNLVENAGTVGAYF
EEECHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCHHHHH
RAELANAVGSHPNVGEVRGDGMLAAVEFVADRDDRVFFDASKKIGPQIAAALAERGVIGR
HHHHHHHHCCCCCCCCCCCCCCEEEEHHHHCCCCEEEEECCHHCCHHHHHHHHHCCCCCC
AMPQGDILGFAPPLCLTKEEADKVIAATASAVDSVLG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDRSNELNAWDRDHFFHPSTHMGTHARGESPNRVVAGGEGVYITDVNGRTSLDAFAGLY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHCEE
CVNVGYGRQKIADAIAEQARNLAYYHAYVGHGTDASIRLAKMIIDRAPQGMSRVYFGLSG
EEECCCCHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHEEEECCC
SDANETNIKLIWYYNNVLGRPEKKKIISRWRGYHGSGIMTGSLTGLDLFHNAFDLPRAPI
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCE
LHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMILAEGPDTVAAFIGEPILGTGGIVPPPA
EECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC
GYWEKIQAVLKKYDVLLIADEVVTGFGRLGTMFGSDHYGIKPDLITIAKGLTSAYAPLSG
CHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCC
VIVSDKVWQVLVQGSDKLGALGHGWTYSAHPLCAAAGVANLELIDEMNLVENAGTVGAYF
EEECHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCHHHHH
RAELANAVGSHPNVGEVRGDGMLAAVEFVADRDDRVFFDASKKIGPQIAAALAERGVIGR
HHHHHHHHCCCCCCCCCCCCCCEEEEHHHHCCCCEEEEECCHHCCHHHHHHHHHCCCCCC
AMPQGDILGFAPPLCLTKEEADKVIAATASAVDSVLG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]