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The map label for this gene is allR [H]

Identifier: 110634722

GI number: 110634722

Start: 2535343

End: 2536107

Strand: Reverse

Name: allR [H]

Synonym: Meso_2380

Alternate gene names: 110634722

Gene position: 2536107-2535343 (Counterclockwise)

Preceding gene: 110634727

Following gene: 110634719

Centisome position: 57.48

GC content: 62.22

Gene sequence:

>765_bases
ATGGCTGGAAGTCAATCGCTGGAACGTGGCCTTGAAATCCTTGAAGTTCTCGACAAGGCGGCGACGCCGCTTGGTGTTCG
CGAGATCGGGCGCCGTCTGAACATCAGCGCGACGATCGTCCAACGACTGGTTAACACCCTGGCGGCGCTGCATTATGTCG
TTCAGGATCCCGAGACGAAACGCTATTCCATAGGGTACCGCGTCCTCGGTCTCGGATGGACGCTGATGAAGAAGGATCCG
CTGATCACCGCCAGCCAGCCGCATTTGGAGCGGCTGGCGAGGTCGCACCTGCTGAACGGCTACCTGGCGAAACTGCACGG
AAGTCGGGCGGTCTATCTGCTGTCGATGCAGAGCGAGGGGCCAATCGCCATCCGCAGCGCGCCGGGCAGCCTGGCGTGGC
TGCACAGCACGGCGATGGGGAAGGTGCTCCTCGCGGCGATGCCGCCCGAACAGGCCTACGCTGTGCTTTCGAGCGAACCG
CTGCCCCAGCTTACCCCCAACACGATCGTCGATATCGACGCTCTGATGAAGCAGATGGAGGAAGTTCGCACCTCCGGCGT
CGCGATATCCAACAGCGAGAATTTGGTCGGAGTCGTTTCGGTCGGTGCGCCATTGCGCGACGGCTCCGGCCAGGTCGTGG
CGGCGCTCAGCGTGGCCTATACCCCTTGGTCCGCGCCTGAAATGTCCACCGAGAAGGCGGCAGAGCTCGTTGTGGATAGT
GCGCTTCAGATCTCTTCCGCCCTTGGCTATTCGCCTGACCGGTAA

Upstream 100 bases:

>100_bases
TAACGCTGTTTCTCTCTTGTACGGATCGCTATTTTCATTGTCAACGGCAGTTGCTTCCGTGCATGGATTGCAAAAGGATT
CGCGGGTATCGGGTAAGAAA

Downstream 100 bases:

>100_bases
AGGCGGCGCGGCATCGCATCCTCTATCCTGCAAGCGATGGCAAATAACAGCTCCTCCGCCCGCATCGGCCCCACAAGCTG
GAGACCGATCGGCAGTCCTT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MAGSQSLERGLEILEVLDKAATPLGVREIGRRLNISATIVQRLVNTLAALHYVVQDPETKRYSIGYRVLGLGWTLMKKDP
LITASQPHLERLARSHLLNGYLAKLHGSRAVYLLSMQSEGPIAIRSAPGSLAWLHSTAMGKVLLAAMPPEQAYAVLSSEP
LPQLTPNTIVDIDALMKQMEEVRTSGVAISNSENLVGVVSVGAPLRDGSGQVVAALSVAYTPWSAPEMSTEKAAELVVDS
ALQISSALGYSPDR

Sequences:

>Translated_254_residues
MAGSQSLERGLEILEVLDKAATPLGVREIGRRLNISATIVQRLVNTLAALHYVVQDPETKRYSIGYRVLGLGWTLMKKDP
LITASQPHLERLARSHLLNGYLAKLHGSRAVYLLSMQSEGPIAIRSAPGSLAWLHSTAMGKVLLAAMPPEQAYAVLSSEP
LPQLTPNTIVDIDALMKQMEEVRTSGVAISNSENLVGVVSVGAPLRDGSGQVVAALSVAYTPWSAPEMSTEKAAELVVDS
ALQISSALGYSPDR
>Mature_253_residues
AGSQSLERGLEILEVLDKAATPLGVREIGRRLNISATIVQRLVNTLAALHYVVQDPETKRYSIGYRVLGLGWTLMKKDPL
ITASQPHLERLARSHLLNGYLAKLHGSRAVYLLSMQSEGPIAIRSAPGSLAWLHSTAMGKVLLAAMPPEQAYAVLSSEPL
PQLTPNTIVDIDALMKQMEEVRTSGVAISNSENLVGVVSVGAPLRDGSGQVVAALSVAYTPWSAPEMSTEKAAELVVDSA
LQISSALGYSPDR

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=250, Percent_Identity=30.4, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786468, Length=246, Percent_Identity=28.0487804878049, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1788131, Length=227, Percent_Identity=27.3127753303965, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789999, Length=255, Percent_Identity=25.4901960784314, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788581, Length=245, Percent_Identity=25.3061224489796, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790752, Length=217, Percent_Identity=25.8064516129032, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=23.0769230769231, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27175; Mature: 27044

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSQSLERGLEILEVLDKAATPLGVREIGRRLNISATIVQRLVNTLAALHYVVQDPETK
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
RYSIGYRVLGLGWTLMKKDPLITASQPHLERLARSHLLNGYLAKLHGSRAVYLLSMQSEG
EEECCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
PIAIRSAPGSLAWLHSTAMGKVLLAAMPPEQAYAVLSSEPLPQLTPNTIVDIDALMKQME
CEEEEECCCCEEHHHHHHHHHEEEEECCCHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
EVRTSGVAISNSENLVGVVSVGAPLRDGSGQVVAALSVAYTPWSAPEMSTEKAAELVVDS
HHHHCCEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHH
ALQISSALGYSPDR
HHHHHHHCCCCCCC
>Mature Secondary Structure 
AGSQSLERGLEILEVLDKAATPLGVREIGRRLNISATIVQRLVNTLAALHYVVQDPETK
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
RYSIGYRVLGLGWTLMKKDPLITASQPHLERLARSHLLNGYLAKLHGSRAVYLLSMQSEG
EEECCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
PIAIRSAPGSLAWLHSTAMGKVLLAAMPPEQAYAVLSSEPLPQLTPNTIVDIDALMKQME
CEEEEECCCCEEHHHHHHHHHEEEEECCCHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
EVRTSGVAISNSENLVGVVSVGAPLRDGSGQVVAALSVAYTPWSAPEMSTEKAAELVVDS
HHHHCCEEEECCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHH
ALQISSALGYSPDR
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA