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The map label for this gene is csd [H]

Identifier: 110634716

GI number: 110634716

Start: 2526358

End: 2527494

Strand: Reverse

Name: csd [H]

Synonym: Meso_2373

Alternate gene names: 110634716

Gene position: 2527494-2526358 (Counterclockwise)

Preceding gene: 110634717

Following gene: 110634715

Centisome position: 57.28

GC content: 63.06

Gene sequence:

>1137_bases
GTGAACCTAGCCGAAGCCCGCAGTGATTTCCCCATCGTCTATCGCCGCGCCTATCTGAATGCCTGTTCGCTCATGCCGCT
GTCCAATCGCGTGGTCGGGGCGGTCCACGCGCAACTCGGCGATCTGCAATTGAACGGCCGCAACAACTCACCGCACCGGA
TCCGCTTTGCCGAGGAGCACATCCGGCCCGCCATCGCCCGGCTGATTGGCGCCGTGCCCGCGGAGATCGCCTTCGTGAAG
AACACGACCGAGGGGCTGAACATCGTCGCCAACGGGATCGACTGGAGAGAGGGCGACAATGTCGTCATCGCCAATATAGA
ATATCCGTCGAACGTCTATTGCTGGCTGAATCTGGCCCGGCGGGGCGTCGAAATCAGATGGATCGATGCCAAAGCGGCCG
GCGGACGTGTCACCGTGGACGACGTCGCCCGCCAAATCGACAGCCGGACGCGGCTTGTGTCGGTGAGTTGCGTCCAGTTC
TCGACCGGATTCCGGCAGGACATGGAGGCGACGGGCGACCTCTGCCGCGAGCGGGGCGTTCTTCTGAACTATGACGCTAT
CCAGGCGGCGGGGGTGCTGGAGATCGACGCGAGCCGCACGCATTTCGATTTCATGTCGGCGGGCGGGCACAAATGGATGG
GTGGCCCTATGGGAACGGGCTTCTTCTATTGCAGGGCGTCCTCGCTTGAGCGTCTACATCCCCACGGCATCGGGCCCGGG
TCGATGACGAATGAGGAGACGGACATCGACTATGACATCGGCCTGATGCAGCCGGATGCGCGCCGCTTCGAAGAGGCGCT
CCCGAACTATCCCGGTCTGTGGGGCCTGCACGCCTCGCTCGGTACAATTTTGGCGCTGGGGCCGCAGGTGGTCGAGGCGC
ACTCGCTCCGCCTCATATCCCGGGCCATCGAAGGGCTGAAGCGAAAGGGTTATCTGATCCACAGTCCGCAGGAGGAAAGG
CACCGCTCCGGCATCCTGACCTTCCGCCATCCCGAACGGAGCAGCGAGGAGCTGAACGAGCGCCTCGTTGAAGCCGGAGT
CGACGTCACCGTCAGGCAGGGCAATCTGCGCATCGCGCCGCACTTCTACAATGACGACGGCGATATCGATTGGCTGCTCG
AGGCATTGCCAGCTTAG

Upstream 100 bases:

>100_bases
TGATGTGTGAGGACACCGGTGTCGTGACCGAAGCAGGTTTCGAGCTCATCTCTTCGATGGACCGCAGCCTTCGGGTCCTG
AATTAAACTGGAGGCCACCA

Downstream 100 bases:

>100_bases
CTAGCGTTCCGGGGTGGCGGGAAACTGTGCCCATGGCGGGCCAGGTTCGTCCGGCAAATCGCTGCGGCACCGCCTGTGTC
GGAGATCCGAACGGCGTGTG

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNLAEARSDFPIVYRRAYLNACSLMPLSNRVVGAVHAQLGDLQLNGRNNSPHRIRFAEEHIRPAIARLIGAVPAEIAFVK
NTTEGLNIVANGIDWREGDNVVIANIEYPSNVYCWLNLARRGVEIRWIDAKAAGGRVTVDDVARQIDSRTRLVSVSCVQF
STGFRQDMEATGDLCRERGVLLNYDAIQAAGVLEIDASRTHFDFMSAGGHKWMGGPMGTGFFYCRASSLERLHPHGIGPG
SMTNEETDIDYDIGLMQPDARRFEEALPNYPGLWGLHASLGTILALGPQVVEAHSLRLISRAIEGLKRKGYLIHSPQEER
HRSGILTFRHPERSSEELNERLVEAGVDVTVRQGNLRIAPHFYNDDGDIDWLLEALPA

Sequences:

>Translated_378_residues
MNLAEARSDFPIVYRRAYLNACSLMPLSNRVVGAVHAQLGDLQLNGRNNSPHRIRFAEEHIRPAIARLIGAVPAEIAFVK
NTTEGLNIVANGIDWREGDNVVIANIEYPSNVYCWLNLARRGVEIRWIDAKAAGGRVTVDDVARQIDSRTRLVSVSCVQF
STGFRQDMEATGDLCRERGVLLNYDAIQAAGVLEIDASRTHFDFMSAGGHKWMGGPMGTGFFYCRASSLERLHPHGIGPG
SMTNEETDIDYDIGLMQPDARRFEEALPNYPGLWGLHASLGTILALGPQVVEAHSLRLISRAIEGLKRKGYLIHSPQEER
HRSGILTFRHPERSSEELNERLVEAGVDVTVRQGNLRIAPHFYNDDGDIDWLLEALPA
>Mature_378_residues
MNLAEARSDFPIVYRRAYLNACSLMPLSNRVVGAVHAQLGDLQLNGRNNSPHRIRFAEEHIRPAIARLIGAVPAEIAFVK
NTTEGLNIVANGIDWREGDNVVIANIEYPSNVYCWLNLARRGVEIRWIDAKAAGGRVTVDDVARQIDSRTRLVSVSCVQF
STGFRQDMEATGDLCRERGVLLNYDAIQAAGVLEIDASRTHFDFMSAGGHKWMGGPMGTGFFYCRASSLERLHPHGIGPG
SMTNEETDIDYDIGLMQPDARRFEEALPNYPGLWGLHASLGTILALGPQVVEAHSLRLISRAIEGLKRKGYLIHSPQEER
HRSGILTFRHPERSSEELNERLVEAGVDVTVRQGNLRIAPHFYNDDGDIDWLLEALPA

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=223, Percent_Identity=29.1479820627803, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1787970, Length=388, Percent_Identity=27.319587628866, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI48994898, Length=234, Percent_Identity=30.3418803418803, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789175, Length=405, Percent_Identity=25.679012345679, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25143064, Length=235, Percent_Identity=28.0851063829787, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=226, Percent_Identity=26.5486725663717, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI20129463, Length=237, Percent_Identity=31.6455696202532, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 42001; Mature: 42001

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAEARSDFPIVYRRAYLNACSLMPLSNRVVGAVHAQLGDLQLNGRNNSPHRIRFAEEH
CCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHHEEHHHEECCEEECCCCCCCCEEEEHHHH
IRPAIARLIGAVPAEIAFVKNTTEGLNIVANGIDWREGDNVVIANIEYPSNVYCWLNLAR
HHHHHHHHHCCCCHHEEEEECCCCCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEEHHH
RGVEIRWIDAKAAGGRVTVDDVARQIDSRTRLVSVSCVQFSTGFRQDMEATGDLCRERGV
CCCEEEEEECCCCCCEEEHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCC
LLNYDAIQAAGVLEIDASRTHFDFMSAGGHKWMGGPMGTGFFYCRASSLERLHPHGIGPG
EEEEHHHHHCCEEEECCCCCEEHHHHCCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCC
SMTNEETDIDYDIGLMQPDARRFEEALPNYPGLWGLHASLGTILALGPQVVEAHSLRLIS
CCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHH
RAIEGLKRKGYLIHSPQEERHRSGILTFRHPERSSEELNERLVEAGVDVTVRQGNLRIAP
HHHHHHHHCCEEEECCHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCEEEEE
HFYNDDGDIDWLLEALPA
EEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MNLAEARSDFPIVYRRAYLNACSLMPLSNRVVGAVHAQLGDLQLNGRNNSPHRIRFAEEH
CCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHHEEHHHEECCEEECCCCCCCCEEEEHHHH
IRPAIARLIGAVPAEIAFVKNTTEGLNIVANGIDWREGDNVVIANIEYPSNVYCWLNLAR
HHHHHHHHHCCCCHHEEEEECCCCCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEEHHH
RGVEIRWIDAKAAGGRVTVDDVARQIDSRTRLVSVSCVQFSTGFRQDMEATGDLCRERGV
CCCEEEEEECCCCCCEEEHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCC
LLNYDAIQAAGVLEIDASRTHFDFMSAGGHKWMGGPMGTGFFYCRASSLERLHPHGIGPG
EEEEHHHHHCCEEEECCCCCEEHHHHCCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCC
SMTNEETDIDYDIGLMQPDARRFEEALPNYPGLWGLHASLGTILALGPQVVEAHSLRLIS
CCCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHH
RAIEGLKRKGYLIHSPQEERHRSGILTFRHPERSSEELNERLVEAGVDVTVRQGNLRIAP
HHHHHHHHCCEEEECCHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCEEEEE
HFYNDDGDIDWLLEALPA
EEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]