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The map label for this gene is pcaR [H]

Identifier: 110634652

GI number: 110634652

Start: 2462283

End: 2463845

Strand: Reverse

Name: pcaR [H]

Synonym: Meso_2307

Alternate gene names: 110634652

Gene position: 2463845-2462283 (Counterclockwise)

Preceding gene: 110634659

Following gene: 110634650

Centisome position: 55.84

GC content: 58.54

Gene sequence:

>1563_bases
ATGAAGGTAAAACGAAGCGATGGTGGTAGCCAGGCGAAGGATATTGTCGCCGCTTTCTCGCGTGGGCTCAGGCTCATTGA
GGCTCTGGCAGCCGGCGGAGATTTAGTCTCGCCATCGGAGCTCGCCGGACGTGTCAAGTTGGATCGCGCAGTCGTTCGGC
GACTGCTTATGACACTTGATCGTTTCGGATACGTGACCGCAGGTGTCCGGGGTTACCGTCTGGCACCGATGGTACGGGAA
CTTGCATTTGCTTATCTCGACAGTATCGGCATTACCGGCGCGTTCGAGCGCGCTCTCTCGCAGGTTTCCCATCTCCTTGG
CGAGACCGTTTCGGTGTCGGTAAGTGATGGCGATGAAATGGTGGTAGTCGCGCGCGCCGATATGAGTGGCCGCCGATTGT
CCTATATCGTTCCACCCGGTACGCGGTTCGCGCTTGCCGAGAGCGCATCCGGGGTTGCGTGGCTTTCCGGGTTGTCGGAG
CAGGCTGCTTGGGACATCGTAGGGAAGCAATCCCTTCGCGGCGCCGCCGGGGCTTTGGCAGCCGAGGTGGAGGCTGCCCG
CTCGAGCGGCTTCGCCACGCGGACTAACGAATATGAAATGGGGCAGTTTGCGATCGCCTGTCCGATCCCGCACCCTCGGA
ATCGTGCGTCTATCGTGCTTCAGGTAGAGCCGTTAGAAGCGCCACGTGATCCAGACGCCTATATAATGGCAAAGGCGCCA
TTGATACGAAAGCATATCCAATTTCTGTCGGAATCACTCTTCGATGTTCCGGGTGGCACTCCTCCTGCGGCGTTTCTCCG
CGAGAACTCGAATGAACCCGCCGCGGTTGCGAGCTTCGAGAGAGGCGTCGATCTAATCTCGCGCTTTGGCAGTAATTTCC
GGGCCGGCACCATCGCTACTGTCGCACGGGAGAACAACCTCGACAGGGCAGTTGCGAGGCGGTTGCTCAAGACGTTGGTG
GCCGGTGGATATGCACAGGTCGAGGATGACGTCTATTCTCTAACAGCACGCATCTTGCGTCTCGGCTTCTATCAGGTTGG
TCATTTGACAATGCCGGAACTGTTTCAACCTCAACTTGAGCGCTTGGCCTTGGCGATAGACGAGTCAACCTCGGCTTATG
TGCTCGACAACGGCGAGGCGCTTTGCATAGCGCGATCCGACATAACCGGCCGACGCATGGGCTACATGATCAACAAGGGA
TCGCGGTTGCCTCTCGCCTATTCCGCCTCGGGACGTGTGCTGCTTTCCACGCTGCCTGAAGATATGCGCCTCCGTCTGCT
GCGCGATATGCCGCCGCCTCCGACCAGTCACAGCGTAATAGGTGTTCATCAGGTGCTCGCGGAGGTGGCGGAGGCGGGTC
GGCAGGGTTACGCCATCAGCAATCAGGAATTGGACGAGGGCATGCTTTCCATGGCGGTTTTGGTTCGTGACCGCGACGGG
AATTCTGTGGGTACATTAGGCTGCAGCTCGCACGTATCACGCATGTCACTCGAGCGCCTGAAGGCTGAAGTCCTGCCCAA
ATTCATCGTCGCCGCGAACGAACTCTCGCGCATTATCCATTAG

Upstream 100 bases:

>100_bases
CGCGGGGCGGTTCGTTGCCATTGGTGGCCATCCTGCATTAGTGATACCGCGACATGGGGGCCGGGCTGTCTGGCGACCGC
AACACTTGGTCGGAACTGCG

Downstream 100 bases:

>100_bases
GGGCTGCGTGGACCTCCGCGTTCCCGGCACTAAGCCGCTCAGCCCCGTTCCGCAGACACGCGACCACCATATCGGCTTCC
ATCACGTCGCCGAAGTTAGA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKVKRSDGGSQAKDIVAAFSRGLRLIEALAAGGDLVSPSELAGRVKLDRAVVRRLLMTLDRFGYVTAGVRGYRLAPMVRE
LAFAYLDSIGITGAFERALSQVSHLLGETVSVSVSDGDEMVVVARADMSGRRLSYIVPPGTRFALAESASGVAWLSGLSE
QAAWDIVGKQSLRGAAGALAAEVEAARSSGFATRTNEYEMGQFAIACPIPHPRNRASIVLQVEPLEAPRDPDAYIMAKAP
LIRKHIQFLSESLFDVPGGTPPAAFLRENSNEPAAVASFERGVDLISRFGSNFRAGTIATVARENNLDRAVARRLLKTLV
AGGYAQVEDDVYSLTARILRLGFYQVGHLTMPELFQPQLERLALAIDESTSAYVLDNGEALCIARSDITGRRMGYMINKG
SRLPLAYSASGRVLLSTLPEDMRLRLLRDMPPPPTSHSVIGVHQVLAEVAEAGRQGYAISNQELDEGMLSMAVLVRDRDG
NSVGTLGCSSHVSRMSLERLKAEVLPKFIVAANELSRIIH

Sequences:

>Translated_520_residues
MKVKRSDGGSQAKDIVAAFSRGLRLIEALAAGGDLVSPSELAGRVKLDRAVVRRLLMTLDRFGYVTAGVRGYRLAPMVRE
LAFAYLDSIGITGAFERALSQVSHLLGETVSVSVSDGDEMVVVARADMSGRRLSYIVPPGTRFALAESASGVAWLSGLSE
QAAWDIVGKQSLRGAAGALAAEVEAARSSGFATRTNEYEMGQFAIACPIPHPRNRASIVLQVEPLEAPRDPDAYIMAKAP
LIRKHIQFLSESLFDVPGGTPPAAFLRENSNEPAAVASFERGVDLISRFGSNFRAGTIATVARENNLDRAVARRLLKTLV
AGGYAQVEDDVYSLTARILRLGFYQVGHLTMPELFQPQLERLALAIDESTSAYVLDNGEALCIARSDITGRRMGYMINKG
SRLPLAYSASGRVLLSTLPEDMRLRLLRDMPPPPTSHSVIGVHQVLAEVAEAGRQGYAISNQELDEGMLSMAVLVRDRDG
NSVGTLGCSSHVSRMSLERLKAEVLPKFIVAANELSRIIH
>Mature_520_residues
MKVKRSDGGSQAKDIVAAFSRGLRLIEALAAGGDLVSPSELAGRVKLDRAVVRRLLMTLDRFGYVTAGVRGYRLAPMVRE
LAFAYLDSIGITGAFERALSQVSHLLGETVSVSVSDGDEMVVVARADMSGRRLSYIVPPGTRFALAESASGVAWLSGLSE
QAAWDIVGKQSLRGAAGALAAEVEAARSSGFATRTNEYEMGQFAIACPIPHPRNRASIVLQVEPLEAPRDPDAYIMAKAP
LIRKHIQFLSESLFDVPGGTPPAAFLRENSNEPAAVASFERGVDLISRFGSNFRAGTIATVARENNLDRAVARRLLKTLV
AGGYAQVEDDVYSLTARILRLGFYQVGHLTMPELFQPQLERLALAIDESTSAYVLDNGEALCIARSDITGRRMGYMINKG
SRLPLAYSASGRVLLSTLPEDMRLRLLRDMPPPPTSHSVIGVHQVLAEVAEAGRQGYAISNQELDEGMLSMAVLVRDRDG
NSVGTLGCSSHVSRMSLERLKAEVLPKFIVAANELSRIIH

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 56118; Mature: 56118

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKRSDGGSQAKDIVAAFSRGLRLIEALAAGGDLVSPSELAGRVKLDRAVVRRLLMTLD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RFGYVTAGVRGYRLAPMVRELAFAYLDSIGITGAFERALSQVSHLLGETVSVSVSDGDEM
HHCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCE
VVVARADMSGRRLSYIVPPGTRFALAESASGVAWLSGLSEQAAWDIVGKQSLRGAAGALA
EEEEECCCCCCEEEEEECCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
AEVEAARSSGFATRTNEYEMGQFAIACPIPHPRNRASIVLQVEPLEAPRDPDAYIMAKAP
HHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCH
LIRKHIQFLSESLFDVPGGTPPAAFLRENSNEPAAVASFERGVDLISRFGSNFRAGTIAT
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
VARENNLDRAVARRLLKTLVAGGYAQVEDDVYSLTARILRLGFYQVGHLTMPELFQPQLE
EHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RLALAIDESTSAYVLDNGEALCIARSDITGRRMGYMINKGSRLPLAYSASGRVLLSTLPE
HHHHHCCCCCCEEEEECCCEEEEECCCCCCCHHCEEECCCCCCCEEECCCCCEEEECCCH
DMRLRLLRDMPPPPTSHSVIGVHQVLAEVAEAGRQGYAISNQELDEGMLSMAVLVRDRDG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHEEECCCC
NSVGTLGCSSHVSRMSLERLKAEVLPKFIVAANELSRIIH
CCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVKRSDGGSQAKDIVAAFSRGLRLIEALAAGGDLVSPSELAGRVKLDRAVVRRLLMTLD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RFGYVTAGVRGYRLAPMVRELAFAYLDSIGITGAFERALSQVSHLLGETVSVSVSDGDEM
HHCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCE
VVVARADMSGRRLSYIVPPGTRFALAESASGVAWLSGLSEQAAWDIVGKQSLRGAAGALA
EEEEECCCCCCEEEEEECCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
AEVEAARSSGFATRTNEYEMGQFAIACPIPHPRNRASIVLQVEPLEAPRDPDAYIMAKAP
HHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCH
LIRKHIQFLSESLFDVPGGTPPAAFLRENSNEPAAVASFERGVDLISRFGSNFRAGTIAT
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
VARENNLDRAVARRLLKTLVAGGYAQVEDDVYSLTARILRLGFYQVGHLTMPELFQPQLE
EHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RLALAIDESTSAYVLDNGEALCIARSDITGRRMGYMINKGSRLPLAYSASGRVLLSTLPE
HHHHHCCCCCCEEEEECCCEEEEECCCCCCCHHCEEECCCCCCCEEECCCCCEEEECCCH
DMRLRLLRDMPPPPTSHSVIGVHQVLAEVAEAGRQGYAISNQELDEGMLSMAVLVRDRDG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHEEECCCC
NSVGTLGCSSHVSRMSLERLKAEVLPKFIVAANELSRIIH
CCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]