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The map label for this gene is malE [C]

Identifier: 110634642

GI number: 110634642

Start: 2449770

End: 2451038

Strand: Reverse

Name: malE [C]

Synonym: Meso_2297

Alternate gene names: 110634642

Gene position: 2451038-2449770 (Counterclockwise)

Preceding gene: 110634643

Following gene: 110634641

Centisome position: 55.55

GC content: 53.9

Gene sequence:

>1269_bases
ATGAAGAAGCTGCTGCTCTGGGCTGCCGCAACGGCACTGTCGAGCCTCACACTCACTGCCGAGCTACACGCCGGCACGGT
GAAAATGTGGACCTTCCTCAACCCTAACAACAATTCGGGCCTTGAAGTGGCCTTGCGCAATATCGTTACAGAGTTCGAGA
AGGAGAACCCGCAAATCGATGTCGTTGTGGAACCCCAAGCCTGGGCGACGATGTCCGAAAAATTCGTGCTCAGCCACAGC
ACGAACACAGCACCTGATATCATCTGGAGCGCAAAGAATCTGGGCTTACTGGTCAATTCGGGATCTCTGGCCCCGCTCAA
TCCCTATTTGGGTGGCTGGGACGGTCCAGAGGGGGGAGATTTGCTGTTTAAGAAAGCTTATGAAAACGCAACGTATGACG
GCAATCTGATGGCTGTCCCAATATTTGCGTACGCCGTGTTACTCTTTTACCGAAAGGATATATTTGAAGAACTCGGATTG
ACTGAAGAGTCGATCGCGACATGGGACGGGTTAATCGAAACCGCTCGGAAACTGAAGGCTGCGGGAAAGCCCGGCTTGCT
TGTTCCGACGTCGGTCGATAAGCCGAGTGAGGGAGTAGCGGCAGATGCCTACGTCCAGCTCAATGGCGGCCAAATGTTCG
ACGAAGGTTGTGTTGCAAACTTTGCCAGCGAGAACGGGCTAAGAGCGTTGGAGCTGCAGGTCCGTATGTTCAAGGAAGGG
ATTCTGTCTCAGGAGGATCTCGTTCGCAACAATGACGATGACTGGGACTTATTCAAGGGTGGCCGTGGCGCCATTATTCC
TCAGGTGAACGACCGGGCGGGTGCTCTCTTCGCATCGACTGACTGGGCCAACGAGAAAACGGTTGGAATCACCCGGTGGC
CCAATTTCCCTGGAGAGACTGAGGGGTCGGCAGTCGGCGCAGCATGGCAAGCATCGCTGTGGACTGGCTCGCAAAATAAA
GAAGAGGCTGCAAAGTTCATCCTTTTCATGGTCAGTAAGTTTGCTGCTCGCCAGTGGGCGCGAGAAGGCAAGTTGCTCCC
AATCCGCGCATCAATCGCTACGGACCCGGAATTCTCGGGCGGAATCTATGAGTTCAACAAAAAAGCGGGCAAGCTTGTGG
AAGAAACCGGTGTGTTTCAACGGCCTGGATGTAACTTCTCTCCGGCGGTCGTTGGCTGGAATACGGCGGTCCAGGAAGTT
GTGCTGAATAATGCAGACCCTATGGAGGTTCTGAAGAAAGTTTCGGCGGATGTGAATCGTCGGCAATGA

Upstream 100 bases:

>100_bases
AACGAAAAGGTGGTAGGGCTGTTGTTGTGCGTTGGGAGGCATGCAACAAGCGGGCATGCGGCGCCGGTTAATATCTTACG
ACTAAGGGATGGAGTTCAGG

Downstream 100 bases:

>100_bases
GCAAGGCTGGTATGCACAGGACCGAGGAGCGCACGCCGGTGCGCTCCTTCATTTGTTTGCGACTGTGTTCTAAGCTAATG
GACTCGTTTTTTTAATAGGG

Product: extracellular solute-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKKLLLWAAATALSSLTLTAELHAGTVKMWTFLNPNNNSGLEVALRNIVTEFEKENPQIDVVVEPQAWATMSEKFVLSHS
TNTAPDIIWSAKNLGLLVNSGSLAPLNPYLGGWDGPEGGDLLFKKAYENATYDGNLMAVPIFAYAVLLFYRKDIFEELGL
TEESIATWDGLIETARKLKAAGKPGLLVPTSVDKPSEGVAADAYVQLNGGQMFDEGCVANFASENGLRALELQVRMFKEG
ILSQEDLVRNNDDDWDLFKGGRGAIIPQVNDRAGALFASTDWANEKTVGITRWPNFPGETEGSAVGAAWQASLWTGSQNK
EEAAKFILFMVSKFAARQWAREGKLLPIRASIATDPEFSGGIYEFNKKAGKLVEETGVFQRPGCNFSPAVVGWNTAVQEV
VLNNADPMEVLKKVSADVNRRQ

Sequences:

>Translated_422_residues
MKKLLLWAAATALSSLTLTAELHAGTVKMWTFLNPNNNSGLEVALRNIVTEFEKENPQIDVVVEPQAWATMSEKFVLSHS
TNTAPDIIWSAKNLGLLVNSGSLAPLNPYLGGWDGPEGGDLLFKKAYENATYDGNLMAVPIFAYAVLLFYRKDIFEELGL
TEESIATWDGLIETARKLKAAGKPGLLVPTSVDKPSEGVAADAYVQLNGGQMFDEGCVANFASENGLRALELQVRMFKEG
ILSQEDLVRNNDDDWDLFKGGRGAIIPQVNDRAGALFASTDWANEKTVGITRWPNFPGETEGSAVGAAWQASLWTGSQNK
EEAAKFILFMVSKFAARQWAREGKLLPIRASIATDPEFSGGIYEFNKKAGKLVEETGVFQRPGCNFSPAVVGWNTAVQEV
VLNNADPMEVLKKVSADVNRRQ
>Mature_422_residues
MKKLLLWAAATALSSLTLTAELHAGTVKMWTFLNPNNNSGLEVALRNIVTEFEKENPQIDVVVEPQAWATMSEKFVLSHS
TNTAPDIIWSAKNLGLLVNSGSLAPLNPYLGGWDGPEGGDLLFKKAYENATYDGNLMAVPIFAYAVLLFYRKDIFEELGL
TEESIATWDGLIETARKLKAAGKPGLLVPTSVDKPSEGVAADAYVQLNGGQMFDEGCVANFASENGLRALELQVRMFKEG
ILSQEDLVRNNDDDWDLFKGGRGAIIPQVNDRAGALFASTDWANEKTVGITRWPNFPGETEGSAVGAAWQASLWTGSQNK
EEAAKFILFMVSKFAARQWAREGKLLPIRASIATDPEFSGGIYEFNKKAGKLVEETGVFQRPGCNFSPAVVGWNTAVQEV
VLNNADPMEVLKKVSADVNRRQ

Specific function: Probably part of an ABC transporter complex [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 46070; Mature: 46070

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLLWAAATALSSLTLTAELHAGTVKMWTFLNPNNNSGLEVALRNIVTEFEKENPQID
CCCEEHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
VVVEPQAWATMSEKFVLSHSTNTAPDIIWSAKNLGLLVNSGSLAPLNPYLGGWDGPEGGD
EEECCCHHHCCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCC
LLFKKAYENATYDGNLMAVPIFAYAVLLFYRKDIFEELGLTEESIATWDGLIETARKLKA
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AGKPGLLVPTSVDKPSEGVAADAYVQLNGGQMFDEGCVANFASENGLRALELQVRMFKEG
CCCCCEEEECCCCCCCCCCEEEEEEEECCCEEECCHHHHHHHCCCCCEEEHHHHHHHHHH
ILSQEDLVRNNDDDWDLFKGGRGAIIPQVNDRAGALFASTDWANEKTVGITRWPNFPGET
CCCHHHHHCCCCCCHHHHCCCCCEECCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCC
EGSAVGAAWQASLWTGSQNKEEAAKFILFMVSKFAARQWAREGKLLPIRASIATDPEFSG
CCCEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
GIYEFNKKAGKLVEETGVFQRPGCNFSPAVVGWNTAVQEVVLNNADPMEVLKKVSADVNR
CCEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCC
RQ
CC
>Mature Secondary Structure
MKKLLLWAAATALSSLTLTAELHAGTVKMWTFLNPNNNSGLEVALRNIVTEFEKENPQID
CCCEEHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
VVVEPQAWATMSEKFVLSHSTNTAPDIIWSAKNLGLLVNSGSLAPLNPYLGGWDGPEGGD
EEECCCHHHCCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCC
LLFKKAYENATYDGNLMAVPIFAYAVLLFYRKDIFEELGLTEESIATWDGLIETARKLKA
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AGKPGLLVPTSVDKPSEGVAADAYVQLNGGQMFDEGCVANFASENGLRALELQVRMFKEG
CCCCCEEEECCCCCCCCCCEEEEEEEECCCEEECCHHHHHHHCCCCCEEEHHHHHHHHHH
ILSQEDLVRNNDDDWDLFKGGRGAIIPQVNDRAGALFASTDWANEKTVGITRWPNFPGET
CCCHHHHHCCCCCCHHHHCCCCCEECCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCC
EGSAVGAAWQASLWTGSQNKEEAAKFILFMVSKFAARQWAREGKLLPIRASIATDPEFSG
CCCEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
GIYEFNKKAGKLVEETGVFQRPGCNFSPAVVGWNTAVQEVVLNNADPMEVLKKVSADVNR
CCEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCC
RQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA