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The map label for this gene is amiD [H]

Identifier: 110634641

GI number: 110634641

Start: 2448286

End: 2449656

Strand: Reverse

Name: amiD [H]

Synonym: Meso_2296

Alternate gene names: 110634641

Gene position: 2449656-2448286 (Counterclockwise)

Preceding gene: 110634642

Following gene: 110634638

Centisome position: 55.52

GC content: 55.07

Gene sequence:

>1371_bases
ATGCATTACCATGATATAATAGGTATTGGGGAATTAATTAGAACAAGAGCCATTTCACCTATAGAGTTAGTTGAAACTAT
AGTTGCTAGAATTAAGGGGATAGATCCGGTACTCAAAAGCTATGCAGAAGTCTTTGAGGAGCACGCACGGCGATCGGCGG
TCAATGCAGAGGCGGAGATTTCGAGGGGTAATTATCGAGGCCCGTTACACGGAATTCCGGTCGCCCTCAAAGACCTGATA
TTTGCCAAGTATGGGCCGACGAAATGCGGAATGACGATCTATCGAGATTTTGTTCCCACGAGCAATGCTACCGTCGTGAC
GAGGCTAGAGGCGGCCGGCGCGATAATCGTCGGTAAGCTGAATATGACGGAAGGAGCTCTTTCTGGTCACCATCCACTTC
TGGATACGCCGAGCAATCCGTGGGGAGCCAATCTCTGGACTGGCGCCTCGTCATCGGGTGCCGGAAGTGCCACCGCCGCG
GGCCTTTGCTTTGCTTCAATCGGTTCGGATAGTGGAGGATCCATCCGTTTGCCGGCGGCCGCGAACGGGCTTACCGGCCT
GAAGCCTACCTGGGGGCTGATCAGTCGCAATGGCGTATTCCCGTTGGCAGAGACCCTGGATCATATAGGTCCAATTGCGC
GCTCTGCCGAAGATATCGCCGTCGTTCTTTCTGCGATCGCTGGGGAGGACACGGAAGATCCGACATCCCTTCGTCAGCCT
GCTCAGGATTACCTGTCCCTTGCAAGGCAGCCGATACGCGGGCTGCGGATCGGTGTAGACGAGGCCTTTGCGTTCGATGG
TGTCGATCCGCAGGTATCAGGCGCATTGCAGGATGCCCTCTCTGTATTCGCGAGATTGGGTGCGCACCTGCGGGTTATGA
AATTCCCATCCACGGCGGATGTGGTACGTCACTGGCGTACGATTTGCTTTTCTGAATGCGCCGTTGCCCATTCTGACACA
TATCCGGCCAGGAAGAATGAGTACGGCCATGATCTTGCCGACCGCATCGAATATGGGCGAAGTCTTTCAGCTACGGACTT
GGCAAAAGCTCTACACTACCTGGCCAAAATCAGAGGGCCCGTGCAGAAGGCAATGGACGAGTGTGACGTATTCATTACGC
CGGCGATGAGTAGTCCGGTGCCGGAAGTGAGTGTCGACTCAAGTAGTTCGGACAGGATGCGTTACATGGCGATCTTTAAT
CTGACCGGCCATCCTGCACTTTCGTTCAATGGCGGGTTTGACATAAGGCAGGCGCCAATTGGCTTGCAGTTGGTGGGCGA
GCACCTCGGCGAAGCCGTTCTCCTGCGAGTGGTTCACGCATTCCAAACGGAAACAGGGTGGCACCTGCAGCGCCCTGCCG
GGTTCCCGTAA

Upstream 100 bases:

>100_bases
GCACAGGACCGAGGAGCGCACGCCGGTGCGCTCCTTCATTTGTTTGCGACTGTGTTCTAAGCTAATGGACTCGTTTTTTT
AATAGGGCGGCGGGCGGAGT

Downstream 100 bases:

>100_bases
CCACGGAGCGAAACACTTTTATATCGGAATCTTCAGGCCTGGATGATTCGTGCCGGACATCGCATCCGCGTGATGAACCG
GAGTGTTGACACGATCAGAC

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MHYHDIIGIGELIRTRAISPIELVETIVARIKGIDPVLKSYAEVFEEHARRSAVNAEAEISRGNYRGPLHGIPVALKDLI
FAKYGPTKCGMTIYRDFVPTSNATVVTRLEAAGAIIVGKLNMTEGALSGHHPLLDTPSNPWGANLWTGASSSGAGSATAA
GLCFASIGSDSGGSIRLPAAANGLTGLKPTWGLISRNGVFPLAETLDHIGPIARSAEDIAVVLSAIAGEDTEDPTSLRQP
AQDYLSLARQPIRGLRIGVDEAFAFDGVDPQVSGALQDALSVFARLGAHLRVMKFPSTADVVRHWRTICFSECAVAHSDT
YPARKNEYGHDLADRIEYGRSLSATDLAKALHYLAKIRGPVQKAMDECDVFITPAMSSPVPEVSVDSSSSDRMRYMAIFN
LTGHPALSFNGGFDIRQAPIGLQLVGEHLGEAVLLRVVHAFQTETGWHLQRPAGFP

Sequences:

>Translated_456_residues
MHYHDIIGIGELIRTRAISPIELVETIVARIKGIDPVLKSYAEVFEEHARRSAVNAEAEISRGNYRGPLHGIPVALKDLI
FAKYGPTKCGMTIYRDFVPTSNATVVTRLEAAGAIIVGKLNMTEGALSGHHPLLDTPSNPWGANLWTGASSSGAGSATAA
GLCFASIGSDSGGSIRLPAAANGLTGLKPTWGLISRNGVFPLAETLDHIGPIARSAEDIAVVLSAIAGEDTEDPTSLRQP
AQDYLSLARQPIRGLRIGVDEAFAFDGVDPQVSGALQDALSVFARLGAHLRVMKFPSTADVVRHWRTICFSECAVAHSDT
YPARKNEYGHDLADRIEYGRSLSATDLAKALHYLAKIRGPVQKAMDECDVFITPAMSSPVPEVSVDSSSSDRMRYMAIFN
LTGHPALSFNGGFDIRQAPIGLQLVGEHLGEAVLLRVVHAFQTETGWHLQRPAGFP
>Mature_456_residues
MHYHDIIGIGELIRTRAISPIELVETIVARIKGIDPVLKSYAEVFEEHARRSAVNAEAEISRGNYRGPLHGIPVALKDLI
FAKYGPTKCGMTIYRDFVPTSNATVVTRLEAAGAIIVGKLNMTEGALSGHHPLLDTPSNPWGANLWTGASSSGAGSATAA
GLCFASIGSDSGGSIRLPAAANGLTGLKPTWGLISRNGVFPLAETLDHIGPIARSAEDIAVVLSAIAGEDTEDPTSLRQP
AQDYLSLARQPIRGLRIGVDEAFAFDGVDPQVSGALQDALSVFARLGAHLRVMKFPSTADVVRHWRTICFSECAVAHSDT
YPARKNEYGHDLADRIEYGRSLSATDLAKALHYLAKIRGPVQKAMDECDVFITPAMSSPVPEVSVDSSSSDRMRYMAIFN
LTGHPALSFNGGFDIRQAPIGLQLVGEHLGEAVLLRVVHAFQTETGWHLQRPAGFP

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=494, Percent_Identity=29.1497975708502, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI195972892, Length=486, Percent_Identity=25.9259259259259, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI166795287, Length=207, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17543272, Length=448, Percent_Identity=29.0178571428571, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17537465, Length=245, Percent_Identity=30.6122448979592, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17556264, Length=300, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538252, Length=190, Percent_Identity=27.8947368421053, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323950, Length=424, Percent_Identity=25.4716981132075, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319685, Length=390, Percent_Identity=25.3846153846154, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320448, Length=235, Percent_Identity=28.5106382978723, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648113, Length=461, Percent_Identity=30.8026030368764, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24652985, Length=477, Percent_Identity=23.8993710691824, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922090, Length=477, Percent_Identity=23.8993710691824, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24652981, Length=477, Percent_Identity=23.8993710691824, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24652983, Length=477, Percent_Identity=23.8993710691824, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI161078093, Length=485, Percent_Identity=25.5670103092783, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24648435, Length=465, Percent_Identity=24.0860215053763, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648437, Length=465, Percent_Identity=24.0860215053763, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45550774, Length=465, Percent_Identity=24.3010752688172, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644968, Length=482, Percent_Identity=23.6514522821577, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356731, Length=477, Percent_Identity=22.0125786163522, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648441, Length=397, Percent_Identity=24.4332493702771, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648439, Length=397, Percent_Identity=24.4332493702771, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 48833; Mature: 48833

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYHDIIGIGELIRTRAISPIELVETIVARIKGIDPVLKSYAEVFEEHARRSAVNAEAEI
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
SRGNYRGPLHGIPVALKDLIFAKYGPTKCGMTIYRDFVPTSNATVVTRLEAAGAIIVGKL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCEEEEEEC
NMTEGALSGHHPLLDTPSNPWGANLWTGASSSGAGSATAAGLCFASIGSDSGGSIRLPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCC
ANGLTGLKPTWGLISRNGVFPLAETLDHIGPIARSAEDIAVVLSAIAGEDTEDPTSLRQP
CCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHH
AQDYLSLARQPIRGLRIGVDEAFAFDGVDPQVSGALQDALSVFARLGAHLRVMKFPSTAD
HHHHHHHHHCCHHHEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
VVRHWRTICFSECAVAHSDTYPARKNEYGHDLADRIEYGRSLSATDLAKALHYLAKIRGP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCH
VQKAMDECDVFITPAMSSPVPEVSVDSSSSDRMRYMAIFNLTGHPALSFNGGFDIRQAPI
HHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCEECCC
GLQLVGEHLGEAVLLRVVHAFQTETGWHLQRPAGFP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCC
>Mature Secondary Structure
MHYHDIIGIGELIRTRAISPIELVETIVARIKGIDPVLKSYAEVFEEHARRSAVNAEAEI
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
SRGNYRGPLHGIPVALKDLIFAKYGPTKCGMTIYRDFVPTSNATVVTRLEAAGAIIVGKL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCEEEEEEC
NMTEGALSGHHPLLDTPSNPWGANLWTGASSSGAGSATAAGLCFASIGSDSGGSIRLPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCC
ANGLTGLKPTWGLISRNGVFPLAETLDHIGPIARSAEDIAVVLSAIAGEDTEDPTSLRQP
CCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHH
AQDYLSLARQPIRGLRIGVDEAFAFDGVDPQVSGALQDALSVFARLGAHLRVMKFPSTAD
HHHHHHHHHCCHHHEEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
VVRHWRTICFSECAVAHSDTYPARKNEYGHDLADRIEYGRSLSATDLAKALHYLAKIRGP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCH
VQKAMDECDVFITPAMSSPVPEVSVDSSSSDRMRYMAIFNLTGHPALSFNGGFDIRQAPI
HHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCEECCC
GLQLVGEHLGEAVLLRVVHAFQTETGWHLQRPAGFP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]