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The map label for this gene is aroE [H]

Identifier: 110634639

GI number: 110634639

Start: 2445931

End: 2446797

Strand: Direct

Name: aroE [H]

Synonym: Meso_2294

Alternate gene names: 110634639

Gene position: 2445931-2446797 (Clockwise)

Preceding gene: 110634636

Following gene: 110634640

Centisome position: 55.43

GC content: 58.59

Gene sequence:

>867_bases
ATGCAATCGGAGCGCATACTGAACCAGTGGAGTCCCGGTGGAACAACCGTCGCGTATCTAATGATCGGCCACCCTACCGT
TCAGGTACGCTCGCCGACGACTTTCAATCGCTGGTTTCGCGAACGCGAAATGGACGCGGTTATGATTGCCGTAGATTTGA
TGCCCGGCGCAGTACCGGATTTTTTTCGAGCGTTACGCGCCCAAGTAAGTGTCGGTGGCGTGATCGTAACGGTCCCACAC
AAGCTCGCGGCGTTTCACGAGATGGACCGATTATCGCGCAGGGCAGAACGGCTCGGCGTCGTCAATGTCGTGCAGCGTCT
GGATGACGGTACGCTACTCGGGGATATGGTCGACGGCCTCGGGTTCACCGGCGCGCTCAGGCGGAATGGATTTTCGCCGC
GAGGCAAGCGTGGCGTCCTGTTCGGAGCCGGAGGGGTGGGCTCGGCGATTGCGCTCGCCTTGCTCGATGACGGTATAGGC
GTACTCGACATTGTCGACCCTGACCAAGCCCGGCTGAACGCACTGTACGATAGGCTCGATAGACCGGCCGGTGCGTGTTT
CACAGAAAGCCGGAGGCACGTAGGTGATGCCGATCTGGTCATAAATGCCACCCCGATTGGAATGAACGGTGATCCAAGAA
TGCCGTTCAATGGTGAAGGGCTTTCCAGCAGAATCTACGTGGCCGATGTCGTGACCAAGCCCGAAGTCACGCCCCTGCTG
ACACTGGCGCAGTCACTCGGATGCAAGATTCAGACCGGCAGTCAGATGGCCGACGCACAATTCGCGCCGTTGGCGCTCGC
CATGGGAATCACCCATCCCGACCTCCAAACCAAAATATTGACCGAGACGAGAAAGAGCGAAGCATGA

Upstream 100 bases:

>100_bases
ATTCGTTGTAGGACAAAGCGATTGACAGGATGTCGAGTGGTGCTTCATGATGTGCGAAGGATCATTAATCGTGCGTCCAG
CGCACTCAACGGGGCAACCG

Downstream 100 bases:

>100_bases
GTGCTCACCTGAGAAGCGAGCGGTACGACGTCGTCGTCATCGGCGCTGGAGCGAGCGGTGTTGCCGCGGCAGCAAGCGCC
GCGCAGAACGGAGCGCGAAC

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MQSERILNQWSPGGTTVAYLMIGHPTVQVRSPTTFNRWFREREMDAVMIAVDLMPGAVPDFFRALRAQVSVGGVIVTVPH
KLAAFHEMDRLSRRAERLGVVNVVQRLDDGTLLGDMVDGLGFTGALRRNGFSPRGKRGVLFGAGGVGSAIALALLDDGIG
VLDIVDPDQARLNALYDRLDRPAGACFTESRRHVGDADLVINATPIGMNGDPRMPFNGEGLSSRIYVADVVTKPEVTPLL
TLAQSLGCKIQTGSQMADAQFAPLALAMGITHPDLQTKILTETRKSEA

Sequences:

>Translated_288_residues
MQSERILNQWSPGGTTVAYLMIGHPTVQVRSPTTFNRWFREREMDAVMIAVDLMPGAVPDFFRALRAQVSVGGVIVTVPH
KLAAFHEMDRLSRRAERLGVVNVVQRLDDGTLLGDMVDGLGFTGALRRNGFSPRGKRGVLFGAGGVGSAIALALLDDGIG
VLDIVDPDQARLNALYDRLDRPAGACFTESRRHVGDADLVINATPIGMNGDPRMPFNGEGLSSRIYVADVVTKPEVTPLL
TLAQSLGCKIQTGSQMADAQFAPLALAMGITHPDLQTKILTETRKSEA
>Mature_288_residues
MQSERILNQWSPGGTTVAYLMIGHPTVQVRSPTTFNRWFREREMDAVMIAVDLMPGAVPDFFRALRAQVSVGGVIVTVPH
KLAAFHEMDRLSRRAERLGVVNVVQRLDDGTLLGDMVDGLGFTGALRRNGFSPRGKRGVLFGAGGVGSAIALALLDDGIG
VLDIVDPDQARLNALYDRLDRPAGACFTESRRHVGDADLVINATPIGMNGDPRMPFNGEGLSSRIYVADVVTKPEVTPLL
TLAQSLGCKIQTGSQMADAQFAPLALAMGITHPDLQTKILTETRKSEA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=236, Percent_Identity=32.6271186440678, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787983, Length=265, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31033; Mature: 31033

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSERILNQWSPGGTTVAYLMIGHPTVQVRSPTTFNRWFREREMDAVMIAVDLMPGAVPD
CCCCHHHHCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCHH
FFRALRAQVSVGGVIVTVPHKLAAFHEMDRLSRRAERLGVVNVVQRLDDGTLLGDMVDGL
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
GFTGALRRNGFSPRGKRGVLFGAGGVGSAIALALLDDGIGVLDIVDPDQARLNALYDRLD
CCCHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHC
RPAGACFTESRRHVGDADLVINATPIGMNGDPRMPFNGEGLSSRIYVADVVTKPEVTPLL
CCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHH
TLAQSLGCKIQTGSQMADAQFAPLALAMGITHPDLQTKILTETRKSEA
HHHHHHCCEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQSERILNQWSPGGTTVAYLMIGHPTVQVRSPTTFNRWFREREMDAVMIAVDLMPGAVPD
CCCCHHHHCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCHH
FFRALRAQVSVGGVIVTVPHKLAAFHEMDRLSRRAERLGVVNVVQRLDDGTLLGDMVDGL
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
GFTGALRRNGFSPRGKRGVLFGAGGVGSAIALALLDDGIGVLDIVDPDQARLNALYDRLD
CCCHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHC
RPAGACFTESRRHVGDADLVINATPIGMNGDPRMPFNGEGLSSRIYVADVVTKPEVTPLL
CCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHH
TLAQSLGCKIQTGSQMADAQFAPLALAMGITHPDLQTKILTETRKSEA
HHHHHHCCEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA