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The map label for this gene is yrhP [H]

Identifier: 110634517

GI number: 110634517

Start: 2317276

End: 2317902

Strand: Direct

Name: yrhP [H]

Synonym: Meso_2168

Alternate gene names: 110634517

Gene position: 2317276-2317902 (Clockwise)

Preceding gene: 110634510

Following gene: 110634519

Centisome position: 52.52

GC content: 59.01

Gene sequence:

>627_bases
ATGAGTCTGCTAGAGATCGTCACCTTTGCCATCGTCGCGGCCCTTCTCGTCCTCTCGCCGGGGCCGAACGGCGTTCTGAT
CGCCAAAACCGTTCCGACCTCGGGCAGGGCGGCGGGCTTCGCCAACATCGCCGGGTTCTTCGCCTCCTTCTACCTGCACG
GAACCCTTTCAGTGCTCGGCATTTCAATCATTCTCGTACAGTCCGCGGAGCTCTTCTTTATCGTCAAGATGCTGGGCGCC
GCCTATCTCAGCTATGTCGGCTTAAAGGCGCTCTGGCAGGCATGGAAGGGAATTGGCCCAGCGAATATCGCACCGGCCAA
AAGCCGCCGCACCCTCGCCCGCGCAGTGGCGGAAGGCTTCCTCACCAACGCACTGAACCCGAAGGTCTCGATGTTCTACC
TGGCGGCCTTCCCCCAGTTTATCCCGATCGGAGCGGAAGCCCAATGGGGATTCGTATTGGTGACGATCCACGCACTCACA
AATGTGGTCTGGTTTTCCAGCCTCGTTCTGCTCTTCTCCGTATTCAAGGGGGTTGGCAGAAGAGCTTGGGTGCAGCGCTG
GCTGAAAGCAATCACCGGAGCGATTTTCGTCGGCTTTGGGCTCAAGCTCGCAATGCTGAAGGCTTGA

Upstream 100 bases:

>100_bases
AACCCGCAATATGGTGCGCGATGGAGCGAATGTCATCATTCCCGTGAATTCGACTTCCGAACAACCGGGTCGATATCCGG
CACTTGAAGGGTAATCTCCG

Downstream 100 bases:

>100_bases
TGCCTACGGCCACTTCACCACGGGCGGCAGGCTGGACAGGATAGAGTTGACATTCCCGCCGGTCTTGAGCCCGAAAATCG
TGCCGCGGTCGTAGAGCAGG

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSLLEIVTFAIVAALLVLSPGPNGVLIAKTVPTSGRAAGFANIAGFFASFYLHGTLSVLGISIILVQSAELFFIVKMLGA
AYLSYVGLKALWQAWKGIGPANIAPAKSRRTLARAVAEGFLTNALNPKVSMFYLAAFPQFIPIGAEAQWGFVLVTIHALT
NVVWFSSLVLLFSVFKGVGRRAWVQRWLKAITGAIFVGFGLKLAMLKA

Sequences:

>Translated_208_residues
MSLLEIVTFAIVAALLVLSPGPNGVLIAKTVPTSGRAAGFANIAGFFASFYLHGTLSVLGISIILVQSAELFFIVKMLGA
AYLSYVGLKALWQAWKGIGPANIAPAKSRRTLARAVAEGFLTNALNPKVSMFYLAAFPQFIPIGAEAQWGFVLVTIHALT
NVVWFSSLVLLFSVFKGVGRRAWVQRWLKAITGAIFVGFGLKLAMLKA
>Mature_207_residues
SLLEIVTFAIVAALLVLSPGPNGVLIAKTVPTSGRAAGFANIAGFFASFYLHGTLSVLGISIILVQSAELFFIVKMLGAA
YLSYVGLKALWQAWKGIGPANIAPAKSRRTLARAVAEGFLTNALNPKVSMFYLAAFPQFIPIGAEAQWGFVLVTIHALTN
VVWFSSLVLLFSVFKGVGRRAWVQRWLKAITGAIFVGFGLKLAMLKA

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=27.1844660194175, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788099, Length=205, Percent_Identity=29.7560975609756, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22261; Mature: 22130

Theoretical pI: Translated: 11.34; Mature: 11.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLEIVTFAIVAALLVLSPGPNGVLIAKTVPTSGRAAGFANIAGFFASFYLHGTLSVLG
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ISIILVQSAELFFIVKMLGAAYLSYVGLKALWQAWKGIGPANIAPAKSRRTLARAVAEGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LTNALNPKVSMFYLAAFPQFIPIGAEAQWGFVLVTIHALTNVVWFSSLVLLFSVFKGVGR
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RAWVQRWLKAITGAIFVGFGLKLAMLKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLLEIVTFAIVAALLVLSPGPNGVLIAKTVPTSGRAAGFANIAGFFASFYLHGTLSVLG
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ISIILVQSAELFFIVKMLGAAYLSYVGLKALWQAWKGIGPANIAPAKSRRTLARAVAEGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LTNALNPKVSMFYLAAFPQFIPIGAEAQWGFVLVTIHALTNVVWFSSLVLLFSVFKGVGR
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
RAWVQRWLKAITGAIFVGFGLKLAMLKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]