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The map label for this gene is aatA [H]

Identifier: 110634456

GI number: 110634456

Start: 2262283

End: 2263485

Strand: Direct

Name: aatA [H]

Synonym: Meso_2107

Alternate gene names: 110634456

Gene position: 2262283-2263485 (Clockwise)

Preceding gene: 110634454

Following gene: 110634458

Centisome position: 51.27

GC content: 60.27

Gene sequence:

>1203_bases
ATGGCTTTCCTTGCCGATGCTCTTTCACGCGTGAAGCCCTCCGCCACCATTGCCGTCACCCAGAAGGCGCGGGAGCTCAA
AGCGCAGGGTCGCGATGTCATCGGACTGGGGGCCGGCGAACCGGATTTCGATACGCCGGACAATATCAAACAGGCCGCGA
TCGAAGCCATCAAGCGCGGCGAAACGAAATATCCGCCCGTCTCCGGCATTCAGCCTCTGCGCGAGGCGATCGCCGCAAAG
TTCAAGCGCGAGAACAATCTCGACTACGACTGGAAGCAGACCATCGTCGGAACGGGTGGTAAGCAGATCCTCTTCAACGC
CTTCATGGCGACACTGAACCCCGGTGATGAAGTGGTGATCCCGACGCCCTATTGGGTGAGCTATCCCGAGATGGTGTCAA
TCTGCGGCGGCACGTCGGTCTTCGCGGAGACCCGGCTGGAAGACAACTTCAAGCTCCAGCCGGAGGTGCTTGAAAGGGCG
ATCACGCCCAGAACCAAGTGGCTTATCATGAACTCGCCATCGAACCCCTCAGGCGCAGCCTATACGCGCGAGGAACTGAA
GGCGGTGGCCGATGTGCTGCTTAAGCATCCGCATGTCTGGGTTCTGACCGACGACATGTATGAGCACCTGACCTATGGCG
ATTTCACCTATCACACCATTGCCGAGGTGGAACCGCAGCTTTACGGACGCACGCTCACCATGAACGGCGTCTCGAAGGCT
TATGCCATGACGGGCTGGCGGATCGGCTATGCGGCAGGACCGATCGAGCTCATCAAGGCCATGGACATGATCCAGGGCCA
GCAGACCTCTGGAGCGGCCACCGTCTGCCAGTTTGCGGCGCTGGAGGCGCTGACCGGACCGCAGGACTTCATCCACCAGA
GCAAAAAGGTCTTTCAGGAGCGCCGCGATCTCGTGGTCTCGATGCTCAACCAGGCGAAAGGCATCAGTTGCCCGGTGCCG
GAAGGTGCGTTCTACGTCTATCCTTCCTGCGCGGGCACGATCGGCAAAAAGGCGCCCTCCGGCAAGCTGATCGAAAGCGA
CACCGATTTCGTCTCCGAACTTCTGGAGACTGAAGGCGTTGCCGTGGTCCAGGGTTCGGCCTTCGGCCTTGGCCCCAATT
TCCGCATCTCCTACGCCACTTCGGACGCGCTGTTGGAAGAGGCCTGCAGCCGCATCCAGCGCTTTACCGCGAACCTTCGC
TAG

Upstream 100 bases:

>100_bases
GCAAAAAAGGGGTGCCTTGCGAATTGACGCGCGATCGGACATTAAGGCGTGTCCCGCGAGCCGAGCGGAACACATCAATT
CCCAGTGGAGAAACCAGCCA

Downstream 100 bases:

>100_bases
AACACATGCCCTCCCCGAGTGGGAGGGCATGTGCATTGCTGGCGCTGGCCTTTGCCAACGCTAGGCATAGCGGGCCAATG
GCTGGGTGCTGCACCGGAAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAFLADALSRVKPSATIAVTQKARELKAQGRDVIGLGAGEPDFDTPDNIKQAAIEAIKRGETKYPPVSGIQPLREAIAAK
FKRENNLDYDWKQTIVGTGGKQILFNAFMATLNPGDEVVIPTPYWVSYPEMVSICGGTSVFAETRLEDNFKLQPEVLERA
ITPRTKWLIMNSPSNPSGAAYTREELKAVADVLLKHPHVWVLTDDMYEHLTYGDFTYHTIAEVEPQLYGRTLTMNGVSKA
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGAATVCQFAALEALTGPQDFIHQSKKVFQERRDLVVSMLNQAKGISCPVP
EGAFYVYPSCAGTIGKKAPSGKLIESDTDFVSELLETEGVAVVQGSAFGLGPNFRISYATSDALLEEACSRIQRFTANLR

Sequences:

>Translated_400_residues
MAFLADALSRVKPSATIAVTQKARELKAQGRDVIGLGAGEPDFDTPDNIKQAAIEAIKRGETKYPPVSGIQPLREAIAAK
FKRENNLDYDWKQTIVGTGGKQILFNAFMATLNPGDEVVIPTPYWVSYPEMVSICGGTSVFAETRLEDNFKLQPEVLERA
ITPRTKWLIMNSPSNPSGAAYTREELKAVADVLLKHPHVWVLTDDMYEHLTYGDFTYHTIAEVEPQLYGRTLTMNGVSKA
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGAATVCQFAALEALTGPQDFIHQSKKVFQERRDLVVSMLNQAKGISCPVP
EGAFYVYPSCAGTIGKKAPSGKLIESDTDFVSELLETEGVAVVQGSAFGLGPNFRISYATSDALLEEACSRIQRFTANLR
>Mature_399_residues
AFLADALSRVKPSATIAVTQKARELKAQGRDVIGLGAGEPDFDTPDNIKQAAIEAIKRGETKYPPVSGIQPLREAIAAKF
KRENNLDYDWKQTIVGTGGKQILFNAFMATLNPGDEVVIPTPYWVSYPEMVSICGGTSVFAETRLEDNFKLQPEVLERAI
TPRTKWLIMNSPSNPSGAAYTREELKAVADVLLKHPHVWVLTDDMYEHLTYGDFTYHTIAEVEPQLYGRTLTMNGVSKAY
AMTGWRIGYAAGPIELIKAMDMIQGQQTSGAATVCQFAALEALTGPQDFIHQSKKVFQERRDLVVSMLNQAKGISCPVPE
GAFYVYPSCAGTIGKKAPSGKLIESDTDFVSELLETEGVAVVQGSAFGLGPNFRISYATSDALLEEACSRIQRFTANLR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=28.0397022332506, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=28.0397022332506, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI56713254, Length=318, Percent_Identity=29.874213836478, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI56713256, Length=318, Percent_Identity=29.874213836478, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881281, Length=399, Percent_Identity=24.812030075188, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4507369, Length=385, Percent_Identity=24.9350649350649, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4885351, Length=365, Percent_Identity=25.7534246575342, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI19263340, Length=375, Percent_Identity=22.6666666666667, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI215599424, Length=375, Percent_Identity=22.6666666666667, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1788627, Length=394, Percent_Identity=28.6802030456853, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=26.5957446808511, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1788722, Length=351, Percent_Identity=30.4843304843305, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=23.3595800524934, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=382, Percent_Identity=26.9633507853403, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=382, Percent_Identity=26.9633507853403, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=255, Percent_Identity=28.6274509803922, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=370, Percent_Identity=23.5135135135135, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=27.4809160305344, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573069, Length=368, Percent_Identity=25.5434782608696, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24646114, Length=368, Percent_Identity=25.5434782608696, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573067, Length=368, Percent_Identity=25.5434782608696, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573065, Length=368, Percent_Identity=25.5434782608696, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=23.8726790450928, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641770, Length=377, Percent_Identity=26.2599469496021, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641760, Length=377, Percent_Identity=26.2599469496021, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641768, Length=377, Percent_Identity=26.2599469496021, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641766, Length=377, Percent_Identity=26.2599469496021, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641764, Length=377, Percent_Identity=26.2599469496021, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551451, Length=371, Percent_Identity=26.1455525606469, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43787; Mature: 43656

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLADALSRVKPSATIAVTQKARELKAQGRDVIGLGAGEPDFDTPDNIKQAAIEAIKRG
CCHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCC
ETKYPPVSGIQPLREAIAAKFKRENNLDYDWKQTIVGTGGKQILFNAFMATLNPGDEVVI
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCHHHHHHHHHHHCCCCCCEEE
PTPYWVSYPEMVSICGGTSVFAETRLEDNFKLQPEVLERAITPRTKWLIMNSPSNPSGAA
CCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCH
YTREELKAVADVLLKHPHVWVLTDDMYEHLTYGDFTYHTIAEVEPQLYGRTLTMNGVSKA
HHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCEEEHHHHHCCHHHCCCEEEECCCHHH
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGAATVCQFAALEALTGPQDFIHQSKKVFQE
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRDLVVSMLNQAKGISCPVPEGAFYVYPSCAGTIGKKAPSGKLIESDTDFVSELLETEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCE
AVVQGSAFGLGPNFRISYATSDALLEEACSRIQRFTANLR
EEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AFLADALSRVKPSATIAVTQKARELKAQGRDVIGLGAGEPDFDTPDNIKQAAIEAIKRG
CHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCC
ETKYPPVSGIQPLREAIAAKFKRENNLDYDWKQTIVGTGGKQILFNAFMATLNPGDEVVI
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCHHHHHHHHHHHCCCCCCEEE
PTPYWVSYPEMVSICGGTSVFAETRLEDNFKLQPEVLERAITPRTKWLIMNSPSNPSGAA
CCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCH
YTREELKAVADVLLKHPHVWVLTDDMYEHLTYGDFTYHTIAEVEPQLYGRTLTMNGVSKA
HHHHHHHHHHHHHHCCCCEEEEECHHHHHCCCCCEEEHHHHHCCHHHCCCEEEECCCHHH
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGAATVCQFAALEALTGPQDFIHQSKKVFQE
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RRDLVVSMLNQAKGISCPVPEGAFYVYPSCAGTIGKKAPSGKLIESDTDFVSELLETEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCE
AVVQGSAFGLGPNFRISYATSDALLEEACSRIQRFTANLR
EEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]