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The map label for this gene is btuC [H]

Identifier: 110634415

GI number: 110634415

Start: 2218681

End: 2219679

Strand: Direct

Name: btuC [H]

Synonym: Meso_2065

Alternate gene names: 110634415

Gene position: 2218681-2219679 (Clockwise)

Preceding gene: 110634414

Following gene: 110634416

Centisome position: 50.28

GC content: 67.37

Gene sequence:

>999_bases
ATGAGGCCGGCCGTCCTCAATATCATTCTTGGCCTGCTGATGCTGGCGCTCTTTGTGGCCTCTATGGCCGTCGGCCCGGC
CGAGCTCGGCATTTCGGAAAGCGTGCGGGGGCTTTTCGCAGGCGGCGGAGAGGCGGCGGGGATCATCATGCGCGAGATCC
GCCTGCCCCGCGCCTTGCTCGGCCTCGGCATCGGCTTCACGCTGGGTATCTCCGGCGCGGTCCTGCAGGGGTTTCTGCGC
AATCCCCTGGCCGAGCCCGGCATTATCGGCGTCTCTGCCATGGCTGCTTTCGGCGCTGTCCTTATCTTCTATTCAGGGCT
CGCGGGCAGCACGCTTTATGCCCTCCCCGCCGGCGCATTGCTGGGCGCGGTGGTGGCCGTTCTCCTCCTCCTGGCGCTCG
CCGCGCGCAGCGGCTCCACACTCACGCTCATCCTGGCGGGCGTGGCGCTCTCCAGTCTTTCCGCCGCGCTCACCTCCCTC
GTGCTCAATCTTTCGCCAAATCCCTTCGCCAGTTACGAGATCATCTTTTGGCTCCTGGGCTCGCTGAAGGACCGCTCCAT
GGAGCATGTCTGGCTCGCGCTCCCCCTCATGGCTGCCGGCTGGCTGCTGATCGCCCTGTCCGGCCGCGCCATCGATGCGC
TTTCGCTTGGCGAGGAGGCGGCGGCAAGCCTCGGCATCCACATGAAACGCACGCGCCTTTTGATCGTGATGGGCACCGCG
CTCGGTGTCGGCGCTGCCACCGCGGTGGCAGGCACGATTGGTTTCGTCGGCCTGGTCGTGCCGCATCTCATCCGGCCGCT
GACGAACCGCCTGCCGAGCCGCCTCCTGCTCCCGGCAGGCCTTGGCGGAGCCGTCCTCCTTCTGGCGGCTGATGTGGCCG
TCCGCCTCGTCTTGCCCGCGGGCGAACTCAATGTGGGCGTGCTGACGGCGCTTATCGGCGCGCCCTTCTTCCTCTGGCTG
GTGGTGCGCTCCCGCCGGGAGGTCTTCTATGCGGCTTGA

Upstream 100 bases:

>100_bases
TGCCAAGGGGCACATGGTCCTGCGGCGGTCCCTTCACGATGGAAGCCGTCAGGGCGCTGGCATCCTTGCGCGAGGATATC
GCACCCTGCGGAGAAACGCG

Downstream 100 bases:

>100_bases
GGTCGAGAATCTCGATGTGGCTCTTTCCGGCCGCCAAGTGCTTCGAGGCATAGCGATGGCCCTTGCCGCCGGCGAGGTGG
TGGGTCTTCTCGGCCCCAAT

Product: transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRPAVLNIILGLLMLALFVASMAVGPAELGISESVRGLFAGGGEAAGIIMREIRLPRALLGLGIGFTLGISGAVLQGFLR
NPLAEPGIIGVSAMAAFGAVLIFYSGLAGSTLYALPAGALLGAVVAVLLLLALAARSGSTLTLILAGVALSSLSAALTSL
VLNLSPNPFASYEIIFWLLGSLKDRSMEHVWLALPLMAAGWLLIALSGRAIDALSLGEEAAASLGIHMKRTRLLIVMGTA
LGVGAATAVAGTIGFVGLVVPHLIRPLTNRLPSRLLLPAGLGGAVLLLAADVAVRLVLPAGELNVGVLTALIGAPFFLWL
VVRSRREVFYAA

Sequences:

>Translated_332_residues
MRPAVLNIILGLLMLALFVASMAVGPAELGISESVRGLFAGGGEAAGIIMREIRLPRALLGLGIGFTLGISGAVLQGFLR
NPLAEPGIIGVSAMAAFGAVLIFYSGLAGSTLYALPAGALLGAVVAVLLLLALAARSGSTLTLILAGVALSSLSAALTSL
VLNLSPNPFASYEIIFWLLGSLKDRSMEHVWLALPLMAAGWLLIALSGRAIDALSLGEEAAASLGIHMKRTRLLIVMGTA
LGVGAATAVAGTIGFVGLVVPHLIRPLTNRLPSRLLLPAGLGGAVLLLAADVAVRLVLPAGELNVGVLTALIGAPFFLWL
VVRSRREVFYAA
>Mature_332_residues
MRPAVLNIILGLLMLALFVASMAVGPAELGISESVRGLFAGGGEAAGIIMREIRLPRALLGLGIGFTLGISGAVLQGFLR
NPLAEPGIIGVSAMAAFGAVLIFYSGLAGSTLYALPAGALLGAVVAVLLLLALAARSGSTLTLILAGVALSSLSAALTSL
VLNLSPNPFASYEIIFWLLGSLKDRSMEHVWLALPLMAAGWLLIALSGRAIDALSLGEEAAASLGIHMKRTRLLIVMGTA
LGVGAATAVAGTIGFVGLVVPHLIRPLTNRLPSRLLLPAGLGGAVLLLAADVAVRLVLPAGELNVGVLTALIGAPFFLWL
VVRSRREVFYAA

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=297, Percent_Identity=41.0774410774411, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=40.5797101449275, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786805, Length=298, Percent_Identity=39.5973154362416, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=35.4385964912281, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786347, Length=290, Percent_Identity=31.3793103448276, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786804, Length=304, Percent_Identity=31.25, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33914; Mature: 33914

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAVLNIILGLLMLALFVASMAVGPAELGISESVRGLFAGGGEAAGIIMREIRLPRALL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GLGIGFTLGISGAVLQGFLRNPLAEPGIIGVSAMAAFGAVLIFYSGLAGSTLYALPAGAL
HHCCHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LGAVVAVLLLLALAARSGSTLTLILAGVALSSLSAALTSLVLNLSPNPFASYEIIFWLLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SLKDRSMEHVWLALPLMAAGWLLIALSGRAIDALSLGEEAAASLGIHMKRTRLLIVMGTA
HHCCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCHHHHHHHCCEEEHHEEEEEEECH
LGVGAATAVAGTIGFVGLVVPHLIRPLTNRLPSRLLLPAGLGGAVLLLAADVAVRLVLPA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHEEEECC
GELNVGVLTALIGAPFFLWLVVRSRREVFYAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MRPAVLNIILGLLMLALFVASMAVGPAELGISESVRGLFAGGGEAAGIIMREIRLPRALL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GLGIGFTLGISGAVLQGFLRNPLAEPGIIGVSAMAAFGAVLIFYSGLAGSTLYALPAGAL
HHCCHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LGAVVAVLLLLALAARSGSTLTLILAGVALSSLSAALTSLVLNLSPNPFASYEIIFWLLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SLKDRSMEHVWLALPLMAAGWLLIALSGRAIDALSLGEEAAASLGIHMKRTRLLIVMGTA
HHCCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHCCHHHHHHHCCEEEHHEEEEEEECH
LGVGAATAVAGTIGFVGLVVPHLIRPLTNRLPSRLLLPAGLGGAVLLLAADVAVRLVLPA
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHEEEECC
GELNVGVLTALIGAPFFLWLVVRSRREVFYAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA