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The map label for this gene is slt [C]

Identifier: 110634367

GI number: 110634367

Start: 2166085

End: 2166702

Strand: Reverse

Name: slt [C]

Synonym: Meso_2017

Alternate gene names: 110634367

Gene position: 2166702-2166085 (Counterclockwise)

Preceding gene: 110634368

Following gene: 110634366

Centisome position: 49.1

GC content: 55.99

Gene sequence:

>618_bases
ATGAAAATCAGGGTCTTTATTGCGACAGCAATCGCTGTCGGGGCGATGACTATTGTCTCGAGTGCAAAGGATGCTTCTCC
TAGGGAAAGTTTAGCGACGGCAAATGCAGAAGCTGCTCCTAGCACTCTGTCGGAAGCAATGAAGCGGGCGCAGGCCAAAA
GCGCCGGGGGCGGTCAAGAGAAGGCGTTGGACGAGACGATCACTGCTTCCACGCGGGTGCCGAAGCAGCCCGCGAAACAG
GATGGGCGCCCCTTTCACTCGATAATCTCCCGCTATGCGGCTCAATATGGCGTGCCTGTTTCGCTCGCCCACGCGGTGGT
ATCGCTGGAAAGCAGCTATCGCCCCACTGTCAGGGGAAGAGCGGGCGAAATCGGCCTGATGCAGATCAAGCCGGCAACCG
CGCGAATGATGGGCTATACCGGTTCCGCAAAGGGCCTTTACGAGCCCGAAACCAACATCAAGTACGGCATGAAATATCTG
GGTAAGGCATTTGAACTGGGGGGCGGTAAAACCTGTTCCGTCATCTTGAAATACAATGCCGGCCATGCGGCAAAGCGCAT
GAACCCCGTTTCCTCTGCTTATTGCGCAAAGGTTAAGCGCCTGATTGGCGGGAAATAA

Upstream 100 bases:

>100_bases
AAACCGAGCCTCATCGGTGGCGGGCGGTATCACTCCGACCGACAAAAGAGAAACCAAGAAACGCAGTTGTCGAAACAGCG
GCGATAAAAAACGGGTAACT

Downstream 100 bases:

>100_bases
GCAAAGCCCATTGCCTTTTGCCTTCGGAATGCCTTTATACGCACTACCAGCCGGTCGGACGGCCGCACGCGCAAGCGCCG
AAAGGCCGCGCGTGAGGAAA

Product: lytic transglycosylase, catalytic

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase; Transglycosylase Protein; Lytic Murein Transglycosylase; Transglycosylase SLT Domain Protein; Soluble Lytic Transglycosylase; Soluble Lytic Murein Transglycosylase; Lytic Transglycosylase; Peptide Deformylase; Transmembrane Protein; Transglycosylase Slt Family; Transglycosylase SLT Domain-Containing Protein; Lytic Transglycosylase Catalytic Subunit

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKIRVFIATAIAVGAMTIVSSAKDASPRESLATANAEAAPSTLSEAMKRAQAKSAGGGQEKALDETITASTRVPKQPAKQ
DGRPFHSIISRYAAQYGVPVSLAHAVVSLESSYRPTVRGRAGEIGLMQIKPATARMMGYTGSAKGLYEPETNIKYGMKYL
GKAFELGGGKTCSVILKYNAGHAAKRMNPVSSAYCAKVKRLIGGK

Sequences:

>Translated_205_residues
MKIRVFIATAIAVGAMTIVSSAKDASPRESLATANAEAAPSTLSEAMKRAQAKSAGGGQEKALDETITASTRVPKQPAKQ
DGRPFHSIISRYAAQYGVPVSLAHAVVSLESSYRPTVRGRAGEIGLMQIKPATARMMGYTGSAKGLYEPETNIKYGMKYL
GKAFELGGGKTCSVILKYNAGHAAKRMNPVSSAYCAKVKRLIGGK
>Mature_205_residues
MKIRVFIATAIAVGAMTIVSSAKDASPRESLATANAEAAPSTLSEAMKRAQAKSAGGGQEKALDETITASTRVPKQPAKQ
DGRPFHSIISRYAAQYGVPVSLAHAVVSLESSYRPTVRGRAGEIGLMQIKPATARMMGYTGSAKGLYEPETNIKYGMKYL
GKAFELGGGKTCSVILKYNAGHAAKRMNPVSSAYCAKVKRLIGGK

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 21598; Mature: 21598

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRVFIATAIAVGAMTIVSSAKDASPRESLATANAEAAPSTLSEAMKRAQAKSAGGGQE
CEEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHH
KALDETITASTRVPKQPAKQDGRPFHSIISRYAAQYGVPVSLAHAVVSLESSYRPTVRGR
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
AGEIGLMQIKPATARMMGYTGSAKGLYEPETNIKYGMKYLGKAFELGGGKTCSVILKYNA
CCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECC
GHAAKRMNPVSSAYCAKVKRLIGGK
CCHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIRVFIATAIAVGAMTIVSSAKDASPRESLATANAEAAPSTLSEAMKRAQAKSAGGGQE
CEEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHH
KALDETITASTRVPKQPAKQDGRPFHSIISRYAAQYGVPVSLAHAVVSLESSYRPTVRGR
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
AGEIGLMQIKPATARMMGYTGSAKGLYEPETNIKYGMKYLGKAFELGGGKTCSVILKYNA
CCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECC
GHAAKRMNPVSSAYCAKVKRLIGGK
CCHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA