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The map label for this gene is ftsA [H]

Identifier: 110634352

GI number: 110634352

Start: 2147958

End: 2149271

Strand: Reverse

Name: ftsA [H]

Synonym: Meso_2002

Alternate gene names: 110634352

Gene position: 2149271-2147958 (Counterclockwise)

Preceding gene: 110634353

Following gene: 110634351

Centisome position: 48.71

GC content: 64.54

Gene sequence:

>1314_bases
ATGAGCTGGCTTCTCGGAAAAGGCGGAGCGGCCCAACGTTCAGGTATCATCACCGTGCTCGATGTGGGGTCGAGTAAGGT
TTCCTGCATCATCGCCAAACTGTTGCCCGACGAAAATATGCGCGCGCTGCCGCATCGCACCCATCGCATTAGGGTGGTGG
GCATCGGTCATCAGAAATCCCAGGGTGTGAAGTCCGGTGTGGTGGTCGATCTCGACCGCGCGGAGCAGGCGATCCGGCTT
GCCGTGGACGCTGCGGAGCGGATGGCGGGCCTCACGGTCGACTCGCTCATCGTCAATGTTTCAGCGGGGCGGATCCGCAG
TGAGACCGCATCCGCCACCATCAATCTCGGCGGGCACGAGGTGGCCAATGCCGATATCGCGCGTGTGCTGCTTGCGGGTG
CCCGCCAGGCCCTGCGTGCGGAGCGCGAGGTGGTGCATTCCCTAGCTGTCGGCTTCTCGCTCGACGTGGAGCGCGGCATT
CGCGACCCGAGGGGCATGATGGGCGATGCGCTCGGCGTCGACATGCATGTGGTCACCGCCGATGCCGTGCCGCTGAGAAA
TCTGGAACTGTGCATCAATCGGGCGCATCTGTCGGTCGAGCGCATGGTCGCGACGCCTTATGCCAGCGGGCTCGCGGCTC
TGGTCGACGACGAAGCGGAGATGGGAGCAGCCTGCATCGACATGGGCGGCGGCACCACGACCATGTCTGTGTTCGTCGAC
GGCAAGTTCGTTCACGCCGATGCCATCCCCGTGGGCGGCAATCATGTGACGATGGATCTGGCGCGCGGCCTCTCAATAAG
GCTTTCCGATGCTGAGCGGCTCAAGGTCATGCAAGGATCCGCACTGCCCGTGACCACCTCCGATGACCGCGAGATGGTCT
CGATACAGCCCATCGGCGGCGACGAGATGGACCAGCCGTTGCAGGTGCCGCGCTCGGTCATGACCCGCATCGTTCGGGCA
CGGGTCGAGGAAACCCTGGAGCTGGTTAGGGACCGGCTCAATCGTTCGGGTTATGGCGCCCTGGTCGGGCGCCGGGTTGT
GCTCACGGGCGGCGCAAGCCAGCTTTCGGGGTTGCCGGAAGCCGCGCGCCGGCTTCTGGGCAGGAATGTTCGCCTCGGGC
GGCCGCTTGGTGTCGCCGGTTTGCCGGAGGCGGCTAAGGGCGCGGCCTTTGCAGCGCCTGTCGGTCTTTTGATCTATCCG
CAGGTTGCGGAATTCGAGAGCCGGGCGGCGGCAAAGGGTGGCCTGTTCATGCGTGCCACAGGGACAGCAGGCAGGTTTCA
GCGTGTCGGACAGTGGTTCCGAGACAGTTTTTGA

Upstream 100 bases:

>100_bases
TGCCGGATCGGCTGACCGTGGCCCTTGCCCCGGAGGCGGCTGAAGCGCGTAAGAAAGAGTTCGAGGAAATGGAGCGGAAA
CGCAAGAAGGGAGCCAGGAC

Downstream 100 bases:

>100_bases
CGGGGGAAAGCCATCAACACCGCGGCGGCGAGGCAGCGGGCAAGGCGGAAAGGACGAAACTTATGACCATCAATCTTAAG
AAGCCGGACATTACCGAGCT

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MSWLLGKGGAAQRSGIITVLDVGSSKVSCIIAKLLPDENMRALPHRTHRIRVVGIGHQKSQGVKSGVVVDLDRAEQAIRL
AVDAAERMAGLTVDSLIVNVSAGRIRSETASATINLGGHEVANADIARVLLAGARQALRAEREVVHSLAVGFSLDVERGI
RDPRGMMGDALGVDMHVVTADAVPLRNLELCINRAHLSVERMVATPYASGLAALVDDEAEMGAACIDMGGGTTTMSVFVD
GKFVHADAIPVGGNHVTMDLARGLSIRLSDAERLKVMQGSALPVTTSDDREMVSIQPIGGDEMDQPLQVPRSVMTRIVRA
RVEETLELVRDRLNRSGYGALVGRRVVLTGGASQLSGLPEAARRLLGRNVRLGRPLGVAGLPEAAKGAAFAAPVGLLIYP
QVAEFESRAAAKGGLFMRATGTAGRFQRVGQWFRDSF

Sequences:

>Translated_437_residues
MSWLLGKGGAAQRSGIITVLDVGSSKVSCIIAKLLPDENMRALPHRTHRIRVVGIGHQKSQGVKSGVVVDLDRAEQAIRL
AVDAAERMAGLTVDSLIVNVSAGRIRSETASATINLGGHEVANADIARVLLAGARQALRAEREVVHSLAVGFSLDVERGI
RDPRGMMGDALGVDMHVVTADAVPLRNLELCINRAHLSVERMVATPYASGLAALVDDEAEMGAACIDMGGGTTTMSVFVD
GKFVHADAIPVGGNHVTMDLARGLSIRLSDAERLKVMQGSALPVTTSDDREMVSIQPIGGDEMDQPLQVPRSVMTRIVRA
RVEETLELVRDRLNRSGYGALVGRRVVLTGGASQLSGLPEAARRLLGRNVRLGRPLGVAGLPEAAKGAAFAAPVGLLIYP
QVAEFESRAAAKGGLFMRATGTAGRFQRVGQWFRDSF
>Mature_436_residues
SWLLGKGGAAQRSGIITVLDVGSSKVSCIIAKLLPDENMRALPHRTHRIRVVGIGHQKSQGVKSGVVVDLDRAEQAIRLA
VDAAERMAGLTVDSLIVNVSAGRIRSETASATINLGGHEVANADIARVLLAGARQALRAEREVVHSLAVGFSLDVERGIR
DPRGMMGDALGVDMHVVTADAVPLRNLELCINRAHLSVERMVATPYASGLAALVDDEAEMGAACIDMGGGTTTMSVFVDG
KFVHADAIPVGGNHVTMDLARGLSIRLSDAERLKVMQGSALPVTTSDDREMVSIQPIGGDEMDQPLQVPRSVMTRIVRAR
VEETLELVRDRLNRSGYGALVGRRVVLTGGASQLSGLPEAARRLLGRNVRLGRPLGVAGLPEAAKGAAFAAPVGLLIYPQ
VAEFESRAAAKGGLFMRATGTAGRFQRVGQWFRDSF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=426, Percent_Identity=28.8732394366197, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 46305; Mature: 46174

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLLGKGGAAQRSGIITVLDVGSSKVSCIIAKLLPDENMRALPHRTHRIRVVGIGHQKS
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHEEECCCCCCCCCCCCCCEEEEEEEECCCCC
QGVKSGVVVDLDRAEQAIRLAVDAAERMAGLTVDSLIVNVSAGRIRSETASATINLGGHE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCEECCCCCEEEECCCCH
VANADIARVLLAGARQALRAEREVVHSLAVGFSLDVERGIRDPRGMMGDALGVDMHVVTA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCCCHHCCCCCCCEEEEEEE
DAVPLRNLELCINRAHLSVERMVATPYASGLAALVDDEAEMGAACIDMGGGTTTMSVFVD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHCCHHHEECCCHHCCCEEEECCCCCEEEEEEEC
GKFVHADAIPVGGNHVTMDLARGLSIRLSDAERLKVMQGSALPVTTSDDREMVSIQPIGG
CEEEEECCEECCCCEEEEEECCCCEEEECCHHHHHHCCCCCCCEECCCCCEEEEEEECCC
DEMDQPLQVPRSVMTRIVRARVEETLELVRDRLNRSGYGALVGRRVVLTGGASQLSGLPE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEECCHHHHCCCHH
AARRLLGRNVRLGRPLGVAGLPEAAKGAAFAAPVGLLIYPQVAEFESRAAAKGGLFMRAT
HHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHCCCCEEEECCHHHHHHHHHHCCCEEEEEC
GTAGRFQRVGQWFRDSF
CCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWLLGKGGAAQRSGIITVLDVGSSKVSCIIAKLLPDENMRALPHRTHRIRVVGIGHQKS
CCCCCCCCCCCCCCEEEEEECCCCCHHHHEEECCCCCCCCCCCCCCEEEEEEEECCCCC
QGVKSGVVVDLDRAEQAIRLAVDAAERMAGLTVDSLIVNVSAGRIRSETASATINLGGHE
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCEECCCCCEEEECCCCH
VANADIARVLLAGARQALRAEREVVHSLAVGFSLDVERGIRDPRGMMGDALGVDMHVVTA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCCCHHCCCCCCCEEEEEEE
DAVPLRNLELCINRAHLSVERMVATPYASGLAALVDDEAEMGAACIDMGGGTTTMSVFVD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHCCHHHEECCCHHCCCEEEECCCCCEEEEEEEC
GKFVHADAIPVGGNHVTMDLARGLSIRLSDAERLKVMQGSALPVTTSDDREMVSIQPIGG
CEEEEECCEECCCCEEEEEECCCCEEEECCHHHHHHCCCCCCCEECCCCCEEEEEEECCC
DEMDQPLQVPRSVMTRIVRARVEETLELVRDRLNRSGYGALVGRRVVLTGGASQLSGLPE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEECCHHHHCCCHH
AARRLLGRNVRLGRPLGVAGLPEAAKGAAFAAPVGLLIYPQVAEFESRAAAKGGLFMRAT
HHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHCCCCEEEECCHHHHHHHHHHCCCEEEEEC
GTAGRFQRVGQWFRDSF
CCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]