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The map label for this gene is rna [C]

Identifier: 110634322

GI number: 110634322

Start: 2114320

End: 2114970

Strand: Direct

Name: rna [C]

Synonym: Meso_1972

Alternate gene names: 110634322

Gene position: 2114320-2114970 (Clockwise)

Preceding gene: 110634321

Following gene: 110634324

Centisome position: 47.92

GC content: 60.22

Gene sequence:

>651_bases
ATGCGAAGATGGGGTGCCGCGCTCTTTTTTGCCGCAGCCATGGCATCATCGGCGGAGGCTGGCGAGCGGGGCTCTGAGCC
CGGCATCTTCGATTTCTACGTGCTCTCGCTCTCCTGGTCGCCCAGCTATTGCGCGGCGGAAGGCACTGAGGCCAATGATG
AGCAATGTGGTTCAACACGGCCTTATGCCTTTGTCGTGCATGGGCTCTGGCCGCAATATGAGAAGGGATATCCTGAATTC
TGCCGAACACGCCAGCCCGAGCGCGTTCCCGGCCGGCTGGTGAAGGCTTATCGCGACATTGTGCCTTCCGCCGGCCTGAT
GGGCCATCAATGGCGCAAGCACGGCTCGTGCAGCGGGCTTGGGCAAAGCGACTATTTCGCTCTGTTGCGGCAGGCGCGGC
AGCGGATCAATATCCCTGCCGAGCTTTCCCGTCTTGATGAGACGCGCTCCGTTTCACCCGCCGACATTGAACAGCAGTTC
CTTGCCGCCAATCTGGATTTGCCTCCGTCGGGAATCGCGGTCACCTGCGACAGACGCTATCTGCGGGAGGTGCGCATTTG
CCTGACGCACGATCTAAGCTTCCGCTCTTGCGGCGAAGTTGATCAAAATGCCTGCCGAAGACCGGAAATAACCATGCCGC
CGGCACGATAA

Upstream 100 bases:

>100_bases
CTGTTTTATCTGCCGCTCCTGCTCCCCACTTTGATGCTTCCGTTCTGGTACAGGAGGACCTGTGCCCAGCCGGTGCGGAT
CAAGAAAAAGCGGAGATAGA

Downstream 100 bases:

>100_bases
GGCCTGTTTCATCCCCTCCCGAAGGAGATGAAAAGAAAAAGCCGGGCAGTGCCCGGCTTCTTCGTTTGGCGTTTGCCGCC
TTTTTTTTAGAACTGCATAC

Product: ribonuclease T2

Products: 3'- Phosphomononucleotides; 3'-Phosphooligonucleotides [C]

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MRRWGAALFFAAAMASSAEAGERGSEPGIFDFYVLSLSWSPSYCAAEGTEANDEQCGSTRPYAFVVHGLWPQYEKGYPEF
CRTRQPERVPGRLVKAYRDIVPSAGLMGHQWRKHGSCSGLGQSDYFALLRQARQRINIPAELSRLDETRSVSPADIEQQF
LAANLDLPPSGIAVTCDRRYLREVRICLTHDLSFRSCGEVDQNACRRPEITMPPAR

Sequences:

>Translated_216_residues
MRRWGAALFFAAAMASSAEAGERGSEPGIFDFYVLSLSWSPSYCAAEGTEANDEQCGSTRPYAFVVHGLWPQYEKGYPEF
CRTRQPERVPGRLVKAYRDIVPSAGLMGHQWRKHGSCSGLGQSDYFALLRQARQRINIPAELSRLDETRSVSPADIEQQF
LAANLDLPPSGIAVTCDRRYLREVRICLTHDLSFRSCGEVDQNACRRPEITMPPAR
>Mature_216_residues
MRRWGAALFFAAAMASSAEAGERGSEPGIFDFYVLSLSWSPSYCAAEGTEANDEQCGSTRPYAFVVHGLWPQYEKGYPEF
CRTRQPERVPGRLVKAYRDIVPSAGLMGHQWRKHGSCSGLGQSDYFALLRQARQRINIPAELSRLDETRSVSPADIEQQF
LAANLDLPPSGIAVTCDRRYLREVRICLTHDLSFRSCGEVDQNACRRPEITMPPAR

Specific function: One of the few RNases that cleave the phosphodiester bond between any two nucleotide. Shows a preference for adenylic acid [H]

COG id: COG3719

COG function: function code J; Ribonuclease I

Gene ontology:

Cell location: Periplasm. Cytoplasm. Note=An RNase I-like form (periplasmic) and RNase I*-like form (cytoplasmic) appear to be isoforms apparently encoded by the same gene. The cytoplasmic form is less active towards natural polymer RNA [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase T2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001568
- InterPro:   IPR018188 [H]

Pfam domain/function: PF00445 Ribonuclease_T2 [H]

EC number: 3.1.27.6 [C]

Molecular weight: Translated: 24194; Mature: 24194

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00530 RNASE_T2_1 ; PS00531 RNASE_T2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRWGAALFFAAAMASSAEAGERGSEPGIFDFYVLSLSWSPSYCAAEGTEANDEQCGSTR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHCCCCC
PYAFVVHGLWPQYEKGYPEFCRTRQPERVPGRLVKAYRDIVPSAGLMGHQWRKHGSCSGL
CEEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCC
GQSDYFALLRQARQRINIPAELSRLDETRSVSPADIEQQFLAANLDLPPSGIAVTCDRRY
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHH
LREVRICLTHDLSFRSCGEVDQNACRRPEITMPPAR
HHHHHHHHHCCCCCHHCCCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRRWGAALFFAAAMASSAEAGERGSEPGIFDFYVLSLSWSPSYCAAEGTEANDEQCGSTR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHCCCCC
PYAFVVHGLWPQYEKGYPEFCRTRQPERVPGRLVKAYRDIVPSAGLMGHQWRKHGSCSGL
CEEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCC
GQSDYFALLRQARQRINIPAELSRLDETRSVSPADIEQQFLAANLDLPPSGIAVTCDRRY
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEECHHH
LREVRICLTHDLSFRSCGEVDQNACRRPEITMPPAR
HHHHHHHHHCCCCCHHCCCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Nucleotides [C]

Specific reaction: Endonucleolytic Cleavage With 2',3'-Cyclic Phosphate Intermediates. [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685334 [H]