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The map label for this gene is iorA [H]

Identifier: 110634256

GI number: 110634256

Start: 2042932

End: 2043426

Strand: Direct

Name: iorA [H]

Synonym: Meso_1906

Alternate gene names: 110634256

Gene position: 2042932-2043426 (Clockwise)

Preceding gene: 110634255

Following gene: 110634257

Centisome position: 46.3

GC content: 63.84

Gene sequence:

>495_bases
ATGGCGATATCCCTGAACGTCAATGGCGAAACGCACGAGGTCGATGTCGATCCCGCGACGCCGCTTCTTTATGTGCTGCG
AAACGATCTTGAGCTGAACGGCGCCAAGTTCGGCTGCGGCCTCGGCCAGTGCGGTTCCTGCACGGTGGTGGTCGATGGCG
CAGCGGTCCTGTCCTGCGTCACCCCTGTCTCGCTGATGGAAGGCCGGGAGATCACCACGGTGGAAGGGCTGGGCACGATC
GAGGAGCCCGGTCCGCTGCAAACCGCCTTCATCGAGATGCAGGCCGCCCAATGCGGCTATTGCATTCCCGGCATGATGAT
GAGCGCTCATGCGCTGCTGACCAGAAACCAGCAGCCCAGCGACCGGGAAATCCGCGACGCGCTCATGACCAATCTGTGCC
GCTGCGGCACGCATATGCGCATCATGGCGGCGATCCGCCGTGCGGGCGAGTTGATGCAGCAAGCGGCTGCCCCGAGCGAG
AGGAGGGCCGGATAA

Upstream 100 bases:

>100_bases
TACGCGCTCGGGCGAGTACAAAGTGGTTATCCTGCCGGCAGACGGCATCGAAAGAGGGCCGGAAAACGTAGGCGCCAGCG
ATGGCGCGGAGGAGTAGGTC

Downstream 100 bases:

>100_bases
TGACCATTGTTCCAAAAGACGGCTTCACCCGCAAAGGGCTCACCCGCCGCAGCGTCCTGACCGGCACCGGCGCACTCGTC
GTCAGCTTCGCGCTTGCCCC

Product: (2Fe-2S)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MAISLNVNGETHEVDVDPATPLLYVLRNDLELNGAKFGCGLGQCGSCTVVVDGAAVLSCVTPVSLMEGREITTVEGLGTI
EEPGPLQTAFIEMQAAQCGYCIPGMMMSAHALLTRNQQPSDREIRDALMTNLCRCGTHMRIMAAIRRAGELMQQAAAPSE
RRAG

Sequences:

>Translated_164_residues
MAISLNVNGETHEVDVDPATPLLYVLRNDLELNGAKFGCGLGQCGSCTVVVDGAAVLSCVTPVSLMEGREITTVEGLGTI
EEPGPLQTAFIEMQAAQCGYCIPGMMMSAHALLTRNQQPSDREIRDALMTNLCRCGTHMRIMAAIRRAGELMQQAAAPSE
RRAG
>Mature_163_residues
AISLNVNGETHEVDVDPATPLLYVLRNDLELNGAKFGCGLGQCGSCTVVVDGAAVLSCVTPVSLMEGREITTVEGLGTIE
EPGPLQTAFIEMQAAQCGYCIPGMMMSAHALLTRNQQPSDREIRDALMTNLCRCGTHMRIMAAIRRAGELMQQAAAPSER
RAG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=152, Percent_Identity=36.8421052631579, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI71773480, Length=154, Percent_Identity=37.6623376623377, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786480, Length=167, Percent_Identity=42.5149700598802, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=37.4149659863946, Blast_Score=98, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=40, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=155, Percent_Identity=39.3548387096774, Blast_Score=112, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=37.5838926174497, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=40.7894736842105, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24647197, Length=161, Percent_Identity=37.2670807453416, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647195, Length=161, Percent_Identity=37.2670807453416, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=30.3225806451613, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17480; Mature: 17349

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
11.0 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
10.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISLNVNGETHEVDVDPATPLLYVLRNDLELNGAKFGCGLGQCGSCTVVVDGAAVLSCV
CEEEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCEEEEECCHHHHHHH
TPVSLMEGREITTVEGLGTIEEPGPLQTAFIEMQAAQCGYCIPGMMMSAHALLTRNQQPS
CHHHHHCCCCEEEECCCCCCCCCCCCHHHHEEHHHHCCCCCCHHHHHHHHHHHHCCCCCC
DREIRDALMTNLCRCGTHMRIMAAIRRAGELMQQAAAPSERRAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AISLNVNGETHEVDVDPATPLLYVLRNDLELNGAKFGCGLGQCGSCTVVVDGAAVLSCV
EEEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCEEEEECCHHHHHHH
TPVSLMEGREITTVEGLGTIEEPGPLQTAFIEMQAAQCGYCIPGMMMSAHALLTRNQQPS
CHHHHHCCCCEEEECCCCCCCCCCCCHHHHEEHHHHCCCCCCHHHHHHHHHHHHCCCCCC
DREIRDALMTNLCRCGTHMRIMAAIRRAGELMQQAAAPSERRAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]