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The map label for this gene is atoS [C]

Identifier: 110634254

GI number: 110634254

Start: 2039488

End: 2041443

Strand: Direct

Name: atoS [C]

Synonym: Meso_1904

Alternate gene names: 110634254

Gene position: 2039488-2041443 (Clockwise)

Preceding gene: 110634253

Following gene: 110634255

Centisome position: 46.22

GC content: 60.48

Gene sequence:

>1956_bases
ATGCTGCGTGCAAACCGGGAGCTTCTTTCGGGGTCGGCGGAAGATCGATATCGCCTTCTGGTGGAGGCGATCACCGATTA
CGCCGTCTACATGCTCGATATCGACGGCTATGTGGTGAGTTGGAATCCCGGCGCGCAGCGCTTCAAAGGGTATGAGGCGT
CCGAAATCATCGGACAGCACTTCTCACAATTTTATACTCCGGAGGATCGAGAGGCGGGACTCCCTCAAAAGGCCCTTGCC
GTTGCGGCTTCTGAAGGCCGTTACGAGGCGGAGGGATGGCGCCTTCGCAAGGACGGCTCGCGTTTCTGGACGCATGCGGT
CATCGATCCCATCCGCGACCCCGCCGGGAGGCTGATCGGCTTTGCCAAGATCACCCGTGACCTGACCGAGCGAAAAGCGG
CGGAGACAGCACTCAAGCAGAGCGAGGAGCAGTTTCGCATTCTGGTCCAAGGCGTGACCGACTATGCCATCTTCATGCTC
GACCCCAACGGCCGCATCATCAGTTGGAACGCAGGCGCCAAGCGTATCAAAGGATACGACGCCAGCGAGATTATCGGCCA
GCATTTCTCGCGCTTCTATATGGAGGACGAGCGGGAACGAGGAGAGCCGCAACGGGGGTTGAAGACCGCCGCCAAGGAAG
GACATTTCGAGAAGGAGGGTTGGCGGGTCCGCAAGGACGGTTCGCGGTTCTGGGCGAGCGTGGTTATCGATGCGATCCGC
GACGAACGGGGTGAACTCATCGGCTTTGCCAAGGTCACGCGCGATATTACGGAGAAGAAGGAAGCCCAGCGCGCTCTGGA
TGAGGCCCGCGAAGCATTGTTCCAGGCACAGAAGCTCGAGGCGATCGGCCAGCTCACCGGCGGCGTGGCGCACGACTTCA
ACAATCTGCTCATGGTCATTCTGAGCAGCTTGGACCTCCTTCGCCGCAAGCTGCCCGACAATGACGAAAGAATCCGCTCG
CTTGTCGACAACGCGGTTCAGGCAGCTCAGCGCGGCGCATCGCTGACCCAGCGTATGCTTTCTTTCGCCCGGCGTCAGGA
ACTGAAGCGCACCGCGGTCGATCTTCCTGAACTGGTTCACGGCATCAGTGATCTTCTGCAGCGCACGCTCGGACCGCTGA
TCAGGATCGAGACGCGGTTTCCACCGACGCTTCCCAAGGTTCATACCGATGCCAACCAGTTTGAATCGGCGCTCCTCAAT
CTGGCGATCAACGCACGGGATGCAATGCCCTCCGGCGGCCCTCTGATCATATCCGCGCGCGAGGAGACGATCTCGGGCGG
CCCGGGCGCCAGGCTTGCGCCCGGCCGCTATGTTTGCCTTTCGGTTGAAGACCGAGGAGAAGGCATGGATGAGGAGACGC
TTGCTCGCGCAACGGACCCCTTTTTCACCACCAAGGGCATTGGCAAGGGTACTGGCCTTGGGCTGTCGATGGTGCAGGGG
CTGGCGGAGCAATCGGGCGGACGGCTGTCCCTGAAAAGCGTAAAGGGAGAAGGCACGACAGCGGAGATGTGGTTGCCAGC
AATCGATGCCGAAGAGCTGGCCCAAATGCGTGAGGAGCCGCGCGATACTCCCTCATCGGAATTCCCCCGGCCCGCGGTGG
TCATGGTTGTGGATGATGATCCTCTGGTACTTCTCAACACAGCGGCAATGCTGGAAGATCTCGGGCATACAGTGATCGAA
GCCTCTGACGCGGAGGAAGCGCTGAACGCGCTGCGGCAGGATAACAATATCGATGTCGTTATAACCGACCAGGCGATGCC
TGGTATGCGGGGTGATGAACTGGCGGGCGCAATCAAGGTGAGCTGGCCGGATCTTCCGGTCATCATTGCGACGGGTTACG
CGGAGCTTTCTCACGCAACGAGGGCCCAGTTCCCACGCCTGTCGAAGCCTTTTGGCCAGAAGCAGCTGGCGAGTAAGCTA
GCCGAGGCCCTCCGATCCCGGCGTCTGACGACCTAG

Upstream 100 bases:

>100_bases
CTTTTTCTGCATTTTACGATAAGCGAGGGGCAACCTTTTCGTGTTTTCCTGCGTTCCCCACTGTTGAATCGTGGGACCGC
AATGCCATGGGCGGGAAATA

Downstream 100 bases:

>100_bases
CCGGGATGCGGCATATATAGCGAAGTGGCCGGCCTCCCGGCTGACTTTCGCAGTGGTGCAGACGGGCGAGGAGACCGATC
GATGCGTTTTACACGTATCC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MLRANRELLSGSAEDRYRLLVEAITDYAVYMLDIDGYVVSWNPGAQRFKGYEASEIIGQHFSQFYTPEDREAGLPQKALA
VAASEGRYEAEGWRLRKDGSRFWTHAVIDPIRDPAGRLIGFAKITRDLTERKAAETALKQSEEQFRILVQGVTDYAIFML
DPNGRIISWNAGAKRIKGYDASEIIGQHFSRFYMEDERERGEPQRGLKTAAKEGHFEKEGWRVRKDGSRFWASVVIDAIR
DERGELIGFAKVTRDITEKKEAQRALDEAREALFQAQKLEAIGQLTGGVAHDFNNLLMVILSSLDLLRRKLPDNDERIRS
LVDNAVQAAQRGASLTQRMLSFARRQELKRTAVDLPELVHGISDLLQRTLGPLIRIETRFPPTLPKVHTDANQFESALLN
LAINARDAMPSGGPLIISAREETISGGPGARLAPGRYVCLSVEDRGEGMDEETLARATDPFFTTKGIGKGTGLGLSMVQG
LAEQSGGRLSLKSVKGEGTTAEMWLPAIDAEELAQMREEPRDTPSSEFPRPAVVMVVDDDPLVLLNTAAMLEDLGHTVIE
ASDAEEALNALRQDNNIDVVITDQAMPGMRGDELAGAIKVSWPDLPVIIATGYAELSHATRAQFPRLSKPFGQKQLASKL
AEALRSRRLTT

Sequences:

>Translated_651_residues
MLRANRELLSGSAEDRYRLLVEAITDYAVYMLDIDGYVVSWNPGAQRFKGYEASEIIGQHFSQFYTPEDREAGLPQKALA
VAASEGRYEAEGWRLRKDGSRFWTHAVIDPIRDPAGRLIGFAKITRDLTERKAAETALKQSEEQFRILVQGVTDYAIFML
DPNGRIISWNAGAKRIKGYDASEIIGQHFSRFYMEDERERGEPQRGLKTAAKEGHFEKEGWRVRKDGSRFWASVVIDAIR
DERGELIGFAKVTRDITEKKEAQRALDEAREALFQAQKLEAIGQLTGGVAHDFNNLLMVILSSLDLLRRKLPDNDERIRS
LVDNAVQAAQRGASLTQRMLSFARRQELKRTAVDLPELVHGISDLLQRTLGPLIRIETRFPPTLPKVHTDANQFESALLN
LAINARDAMPSGGPLIISAREETISGGPGARLAPGRYVCLSVEDRGEGMDEETLARATDPFFTTKGIGKGTGLGLSMVQG
LAEQSGGRLSLKSVKGEGTTAEMWLPAIDAEELAQMREEPRDTPSSEFPRPAVVMVVDDDPLVLLNTAAMLEDLGHTVIE
ASDAEEALNALRQDNNIDVVITDQAMPGMRGDELAGAIKVSWPDLPVIIATGYAELSHATRAQFPRLSKPFGQKQLASKL
AEALRSRRLTT
>Mature_651_residues
MLRANRELLSGSAEDRYRLLVEAITDYAVYMLDIDGYVVSWNPGAQRFKGYEASEIIGQHFSQFYTPEDREAGLPQKALA
VAASEGRYEAEGWRLRKDGSRFWTHAVIDPIRDPAGRLIGFAKITRDLTERKAAETALKQSEEQFRILVQGVTDYAIFML
DPNGRIISWNAGAKRIKGYDASEIIGQHFSRFYMEDERERGEPQRGLKTAAKEGHFEKEGWRVRKDGSRFWASVVIDAIR
DERGELIGFAKVTRDITEKKEAQRALDEAREALFQAQKLEAIGQLTGGVAHDFNNLLMVILSSLDLLRRKLPDNDERIRS
LVDNAVQAAQRGASLTQRMLSFARRQELKRTAVDLPELVHGISDLLQRTLGPLIRIETRFPPTLPKVHTDANQFESALLN
LAINARDAMPSGGPLIISAREETISGGPGARLAPGRYVCLSVEDRGEGMDEETLARATDPFFTTKGIGKGTGLGLSMVQG
LAEQSGGRLSLKSVKGEGTTAEMWLPAIDAEELAQMREEPRDTPSSEFPRPAVVMVVDDDPLVLLNTAAMLEDLGHTVIE
ASDAEEALNALRQDNNIDVVITDQAMPGMRGDELAGAIKVSWPDLPVIIATGYAELSHATRAQFPRLSKPFGQKQLASKL
AEALRSRRLTT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=378, Percent_Identity=26.984126984127, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=31.4655172413793, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI48994928, Length=406, Percent_Identity=25.1231527093596, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=29.0196078431373, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=398, Percent_Identity=23.8693467336683, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790861, Length=254, Percent_Identity=27.1653543307087, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081816, Length=180, Percent_Identity=28.3333333333333, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72105; Mature: 72105

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRANRELLSGSAEDRYRLLVEAITDYAVYMLDIDGYVVSWNPGAQRFKGYEASEIIGQH
CCCCCHHHHCCCCHHHHHHHHHHHHHHEEEEEEECCEEEEECCCHHHHCCCCHHHHHHHH
FSQFYTPEDREAGLPQKALAVAASEGRYEAEGWRLRKDGSRFWTHAVIDPIRDPAGRLIG
HHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHHH
FAKITRDLTERKAAETALKQSEEQFRILVQGVTDYAIFMLDPNGRIISWNAGAKRIKGYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCHHHCCCC
ASEIIGQHFSRFYMEDERERGEPQRGLKTAAKEGHFEKEGWRVRKDGSRFWASVVIDAIR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHH
DERGELIGFAKVTRDITEKKEAQRALDEAREALFQAQKLEAIGQLTGGVAHDFNNLLMVI
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LSSLDLLRRKLPDNDERIRSLVDNAVQAAQRGASLTQRMLSFARRQELKRTAVDLPELVH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GISDLLQRTLGPLIRIETRFPPTLPKVHTDANQFESALLNLAINARDAMPSGGPLIISAR
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCEEEEEC
EETISGGPGARLAPGRYVCLSVEDRGEGMDEETLARATDPFFTTKGIGKGTGLGLSMVQG
HHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHH
LAEQSGGRLSLKSVKGEGTTAEMWLPAIDAEELAQMREEPRDTPSSEFPRPAVVMVVDDD
HHHCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
PLVLLNTAAMLEDLGHTVIEASDAEEALNALRQDNNIDVVITDQAMPGMRGDELAGAIKV
CEEEEHHHHHHHHHCHHHEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEE
SWPDLPVIIATGYAELSHATRAQFPRLSKPFGQKQLASKLAEALRSRRLTT
CCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLRANRELLSGSAEDRYRLLVEAITDYAVYMLDIDGYVVSWNPGAQRFKGYEASEIIGQH
CCCCCHHHHCCCCHHHHHHHHHHHHHHEEEEEEECCEEEEECCCHHHHCCCCHHHHHHHH
FSQFYTPEDREAGLPQKALAVAASEGRYEAEGWRLRKDGSRFWTHAVIDPIRDPAGRLIG
HHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHHH
FAKITRDLTERKAAETALKQSEEQFRILVQGVTDYAIFMLDPNGRIISWNAGAKRIKGYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCHHHCCCC
ASEIIGQHFSRFYMEDERERGEPQRGLKTAAKEGHFEKEGWRVRKDGSRFWASVVIDAIR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHH
DERGELIGFAKVTRDITEKKEAQRALDEAREALFQAQKLEAIGQLTGGVAHDFNNLLMVI
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
LSSLDLLRRKLPDNDERIRSLVDNAVQAAQRGASLTQRMLSFARRQELKRTAVDLPELVH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
GISDLLQRTLGPLIRIETRFPPTLPKVHTDANQFESALLNLAINARDAMPSGGPLIISAR
HHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCEEEEEC
EETISGGPGARLAPGRYVCLSVEDRGEGMDEETLARATDPFFTTKGIGKGTGLGLSMVQG
HHHCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCEECCCCCCCCCCHHHHHHH
LAEQSGGRLSLKSVKGEGTTAEMWLPAIDAEELAQMREEPRDTPSSEFPRPAVVMVVDDD
HHHCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
PLVLLNTAAMLEDLGHTVIEASDAEEALNALRQDNNIDVVITDQAMPGMRGDELAGAIKV
CEEEEHHHHHHHHHCHHHEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEE
SWPDLPVIIATGYAELSHATRAQFPRLSKPFGQKQLASKLAEALRSRRLTT
CCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA