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The map label for this gene is ftsK [H]

Identifier: 110634229

GI number: 110634229

Start: 2018150

End: 2020798

Strand: Reverse

Name: ftsK [H]

Synonym: Meso_1879

Alternate gene names: 110634229

Gene position: 2020798-2018150 (Counterclockwise)

Preceding gene: 110634230

Following gene: 110634228

Centisome position: 45.8

GC content: 63.68

Gene sequence:

>2649_bases
ATGCAGTTTTCCCGTAAAAATTTCCGAACTCAAGCATTGCGCCACCACGCCCCGACAGCCGTGGAGAATCACGAGAAGGC
CGATCTTTCGCGGGCGCAGCCTGCTTCCGCGGAACCTCGCTTGAGCGGGAAGACAGCGCCGACAAATCAGGCCGCTTTGC
AAGACCGCGAGCCACTCGAACGGCAAAGCCTGGATAAGGCAGGCTCCGGGCAAAGCAGGATTGCCGAACCCGGCGCACGG
TCGTTGCTGAGGCAGGTCGAGGACAAGTTCAGGGACCAACCCTGGCAATCTTATTTCTACCTGGCGCCTAATGTACGCTT
CACCCGAACGCCGGAACGGCGGCCCGCCGCGGAGACGGACCAAGAAGCCACGGCTGCAAGCCGGGAATCAGCGACTTTCA
CCGGGCGCATTGCGAGCAGCACCGCTCGTGAGAGAACACCGGCCAAGCCGGTCGAGGTGCCGCCGAGCGCGTACGCCTTC
GGCTCGCTGCTGGGGCAGGGGCTGGAGCTTTCGGCATTGGCGATGAAGCCGAGGGCGAAAGGTTATGCTTCCGTAAGCGT
GGAGCAGGGCGGCAGTTGGCGCGAGGGGGGAGTTTCCCCGCAGCCGGAAGACCGGAATGCCTCGAAAAGGAGCTGTTCTG
CTGCGCGTGCGGCATGCTGGCGCGATCTTTCCGACCATGCATTCTTCGAGCTGATGCCTTTCGATGAGTCCGAGGACTGG
GTCCCGGCTTCTTTCAGGCAGGTAGCCGTAAAGACGCAGGCCCAACGATCCGCAGTTCCGGCAGCGGCCCGACAGGTCAG
GCTCCCGGTTGCCGGCGCATCCGAGATCACGTCGCTGTTCCGGGTGATCGAATGCTCTCCACCTCCCGCTTCGGACGCCG
TGAATGCACCCTTGCCGGAACCCAAAGCCGAGGTTCGGTACGAGACGAGCACCGCGGCGACGGAAGAGCGGATCATGGCG
GCCGACGCGGCAAGCAGGGAGAACGCCGCGCGCGAGCGGGACCGGCAAGCTGCGGGACGGGTAGTCCCTTTCCCGCCGGC
TCCGATGAAGAGGGCTTCTGCCCCCGTGGTCGTTGCTCCCAGGCATTCTCTGGCGGCGGGCGGCTCCTATGAATTTCCCT
CTGAAGAATTGTTGCAGAACCCGCCGGAAGGGCAGGGCTTCTACATGACCCAGGAGCAGATCGAGCAGAATGCCGGGCTC
CTGGAGAATGTTCTGGAAGATTTCGGCGTGCGAGGCGAAATCATCCATGTCCGCCCCGGCCCGGTGGTGACGCTTTATGA
ATTCGAGCCGGCGCCAGGGGTGAAATCCTCGCGCGTGATCAACCTGGCCGACGACATCGCCCGTTCCATGTCGGCCGTGT
CGGCGCGCGTGGCTGTGGTGCCGGGCCGCAACGTGATCGGCATCGAGCTGCCGAATGTGGAGCGCGAAACCGTTTATCTG
CGCGAGCTGATTCAGTCGGGCGACTTCCACAAGACCGGCTACAAGCTGGCCCTGTGTCTCGGCAAGACGATCGGCGGAGA
GGCGGTTATCGCCGAGCTCGCGAAGATGCCGCACCTGCTCGTGGCTGGCACGACCGGCTCGGGAAAGTCGGTCGCCATCA
ACACTATGATTCTGTCACTGCTCTATCGGCTGCGGCCGGAGGAGTGCCGGCTGATCATGGTCGATCCGAAAATGCTGGAG
CTTTCCGTCTATGACGGCATCCCGCATCTGCTGACGCCCGTGGTGACCGATCCGAAGAAGGCGGTGACGGCGCTCAAATG
GGCGGTGCGCGAGATGGAGGACCGCTATCGCAAGATGGCGCGGCTCGGCGTGCGCAATATCGACGGCTATAACCAACGCG
CCGCCACGGCGCGCGACAAGGGCGAGCCGGTGCTCATCTCCGTCCAGACCGGCTTCGACCGTTCAACCGGTGAACCCATC
TACGAAGAGCAGGAGATGGACCTTGCGCCCATGCCCTATATCGTCGTGATCGTCGACGAGATGGCCGACCTGATGATGGT
CGCGGGCAAGGAGATCGAGGGGGCGATCCAGCGCCTTGCGCAGATGGCGCGGGCCGCCGGCATCCATCTGATCATGGCAA
CGCAGCGTCCCTCGGTCGATGTGATTACAGGCACGATCAAGGCCAATTTCCCAACGCGCATCTCCTTCCAGGTGACGTCG
AAGATCGACAGCCGCACGATCCTCGGCGAGCAGGGTGCCGAGCAGCTCCTGGGCCAGGGAGACATGCTGCACATGTCCGG
CGGCGGGCGCATCGTGCGCGTGCACGGCCCCTTCGTCTCCGACGAGGAGGTGGAGCAGGTCGTGGCGCATTTGAAGACGC
AGGGACGCCCGGAATATCTGGACACCGTCACCGCCGATGAGGAGGAGGAGCAGGCGCCGGAGGAGGACAGCGCGGTGTTT
GACAAGGGGGCAATTGCCTCCGAGGACGGCAACGAAATCTATGATCAGGCGGTCAAGGTGGTGCTGCGCGACAAGAGGTG
CTCCACCTCCTATATCCAGCGCAGGCTGGGCATTGGCTATAACCGCGCTGCCTCGCTGATCGAGCGGATGGAGAAGGAAG
GCCTGGTGGGCAAGCCCAACCATGTCGGCAAGCGGGAAATCCTCATGGGCGGCCGGGATGTGGGGCCGAGCAGCGGCGAC
GGAGATTGA

Upstream 100 bases:

>100_bases
TCCGTTTTTTTGCCGCCGGAGGTGCCTGCTTATGGAAGCTGTTAACCTTCATTTTTTATTGCCTATGGGGAGAGTCGCGT
CAGGATTCGAGTCTACCGTC

Downstream 100 bases:

>100_bases
CGCGACTTGCCGGCTGGGCGGGAGGATATTACATCCGCCGCGGCCGGCGGGTTTCCGGCAGCAGGGGAAATCGTCAAGAA
CGGGCGGTCTCCGCTTGACG

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 882; Mature: 882

Protein sequence:

>882_residues
MQFSRKNFRTQALRHHAPTAVENHEKADLSRAQPASAEPRLSGKTAPTNQAALQDREPLERQSLDKAGSGQSRIAEPGAR
SLLRQVEDKFRDQPWQSYFYLAPNVRFTRTPERRPAAETDQEATAASRESATFTGRIASSTARERTPAKPVEVPPSAYAF
GSLLGQGLELSALAMKPRAKGYASVSVEQGGSWREGGVSPQPEDRNASKRSCSAARAACWRDLSDHAFFELMPFDESEDW
VPASFRQVAVKTQAQRSAVPAAARQVRLPVAGASEITSLFRVIECSPPPASDAVNAPLPEPKAEVRYETSTAATEERIMA
ADAASRENAARERDRQAAGRVVPFPPAPMKRASAPVVVAPRHSLAAGGSYEFPSEELLQNPPEGQGFYMTQEQIEQNAGL
LENVLEDFGVRGEIIHVRPGPVVTLYEFEPAPGVKSSRVINLADDIARSMSAVSARVAVVPGRNVIGIELPNVERETVYL
RELIQSGDFHKTGYKLALCLGKTIGGEAVIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRLRPEECRLIMVDPKMLE
LSVYDGIPHLLTPVVTDPKKAVTALKWAVREMEDRYRKMARLGVRNIDGYNQRAATARDKGEPVLISVQTGFDRSTGEPI
YEEQEMDLAPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTS
KIDSRTILGEQGAEQLLGQGDMLHMSGGGRIVRVHGPFVSDEEVEQVVAHLKTQGRPEYLDTVTADEEEEQAPEEDSAVF
DKGAIASEDGNEIYDQAVKVVLRDKRCSTSYIQRRLGIGYNRAASLIERMEKEGLVGKPNHVGKREILMGGRDVGPSSGD
GD

Sequences:

>Translated_882_residues
MQFSRKNFRTQALRHHAPTAVENHEKADLSRAQPASAEPRLSGKTAPTNQAALQDREPLERQSLDKAGSGQSRIAEPGAR
SLLRQVEDKFRDQPWQSYFYLAPNVRFTRTPERRPAAETDQEATAASRESATFTGRIASSTARERTPAKPVEVPPSAYAF
GSLLGQGLELSALAMKPRAKGYASVSVEQGGSWREGGVSPQPEDRNASKRSCSAARAACWRDLSDHAFFELMPFDESEDW
VPASFRQVAVKTQAQRSAVPAAARQVRLPVAGASEITSLFRVIECSPPPASDAVNAPLPEPKAEVRYETSTAATEERIMA
ADAASRENAARERDRQAAGRVVPFPPAPMKRASAPVVVAPRHSLAAGGSYEFPSEELLQNPPEGQGFYMTQEQIEQNAGL
LENVLEDFGVRGEIIHVRPGPVVTLYEFEPAPGVKSSRVINLADDIARSMSAVSARVAVVPGRNVIGIELPNVERETVYL
RELIQSGDFHKTGYKLALCLGKTIGGEAVIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRLRPEECRLIMVDPKMLE
LSVYDGIPHLLTPVVTDPKKAVTALKWAVREMEDRYRKMARLGVRNIDGYNQRAATARDKGEPVLISVQTGFDRSTGEPI
YEEQEMDLAPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTS
KIDSRTILGEQGAEQLLGQGDMLHMSGGGRIVRVHGPFVSDEEVEQVVAHLKTQGRPEYLDTVTADEEEEQAPEEDSAVF
DKGAIASEDGNEIYDQAVKVVLRDKRCSTSYIQRRLGIGYNRAASLIERMEKEGLVGKPNHVGKREILMGGRDVGPSSGD
GD
>Mature_882_residues
MQFSRKNFRTQALRHHAPTAVENHEKADLSRAQPASAEPRLSGKTAPTNQAALQDREPLERQSLDKAGSGQSRIAEPGAR
SLLRQVEDKFRDQPWQSYFYLAPNVRFTRTPERRPAAETDQEATAASRESATFTGRIASSTARERTPAKPVEVPPSAYAF
GSLLGQGLELSALAMKPRAKGYASVSVEQGGSWREGGVSPQPEDRNASKRSCSAARAACWRDLSDHAFFELMPFDESEDW
VPASFRQVAVKTQAQRSAVPAAARQVRLPVAGASEITSLFRVIECSPPPASDAVNAPLPEPKAEVRYETSTAATEERIMA
ADAASRENAARERDRQAAGRVVPFPPAPMKRASAPVVVAPRHSLAAGGSYEFPSEELLQNPPEGQGFYMTQEQIEQNAGL
LENVLEDFGVRGEIIHVRPGPVVTLYEFEPAPGVKSSRVINLADDIARSMSAVSARVAVVPGRNVIGIELPNVERETVYL
RELIQSGDFHKTGYKLALCLGKTIGGEAVIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRLRPEECRLIMVDPKMLE
LSVYDGIPHLLTPVVTDPKKAVTALKWAVREMEDRYRKMARLGVRNIDGYNQRAATARDKGEPVLISVQTGFDRSTGEPI
YEEQEMDLAPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTS
KIDSRTILGEQGAEQLLGQGDMLHMSGGGRIVRVHGPFVSDEEVEQVVAHLKTQGRPEYLDTVTADEEEEQAPEEDSAVF
DKGAIASEDGNEIYDQAVKVVLRDKRCSTSYIQRRLGIGYNRAASLIERMEKEGLVGKPNHVGKREILMGGRDVGPSSGD
GD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=500, Percent_Identity=52, Blast_Score=495, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 96255; Mature: 96255

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSRKNFRTQALRHHAPTAVENHEKADLSRAQPASAEPRLSGKTAPTNQAALQDREPLE
CCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCHH
RQSLDKAGSGQSRIAEPGARSLLRQVEDKFRDQPWQSYFYLAPNVRFTRTPERRPAAETD
HHHHCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCCCC
QEATAASRESATFTGRIASSTARERTPAKPVEVPPSAYAFGSLLGQGLELSALAMKPRAK
HHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
GYASVSVEQGGSWREGGVSPQPEDRNASKRSCSAARAACWRDLSDHAFFELMPFDESEDW
CCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
VPASFRQVAVKTQAQRSAVPAAARQVRLPVAGASEITSLFRVIECSPPPASDAVNAPLPE
CCHHHHHHHHHHHHHHHHCCHHHHHEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PKAEVRYETSTAATEERIMAADAASRENAARERDRQAAGRVVPFPPAPMKRASAPVVVAP
CCHHEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEEEC
RHSLAAGGSYEFPSEELLQNPPEGQGFYMTQEQIEQNAGLLENVLEDFGVRGEIIHVRPG
CCCCCCCCCCCCCCHHHHCCCCCCCCEEECHHHHHHCCCHHHHHHHHCCCCCEEEEECCC
PVVTLYEFEPAPGVKSSRVINLADDIARSMSAVSARVAVVPGRNVIGIELPNVERETVYL
CEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCHHHHHH
RELIQSGDFHKTGYKLALCLGKTIGGEAVIAELAKMPHLLVAGTTGSGKSVAINTMILSL
HHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCEEHHHHHHHHH
LYRLRPEECRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVTALKWAVREMEDRYRKMA
HHHCCCCCCEEEEECCCEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLGVRNIDGYNQRAATARDKGEPVLISVQTGFDRSTGEPIYEEQEMDLAPMPYIVVIVDE
HHCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEHHH
MADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTS
HHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCEEEEEEEC
KIDSRTILGEQGAEQLLGQGDMLHMSGGGRIVRVHGPFVSDEEVEQVVAHLKTQGRPEYL
CCCCHHECCHHHHHHHHCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHH
DTVTADEEEEQAPEEDSAVFDKGAIASEDGNEIYDQAVKVVLRDKRCSTSYIQRRLGIGY
HCCCCCCHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
NRAASLIERMEKEGLVGKPNHVGKREILMGGRDVGPSSGDGD
HHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCCCCCCCC
>Mature Secondary Structure
MQFSRKNFRTQALRHHAPTAVENHEKADLSRAQPASAEPRLSGKTAPTNQAALQDREPLE
CCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCHH
RQSLDKAGSGQSRIAEPGARSLLRQVEDKFRDQPWQSYFYLAPNVRFTRTPERRPAAETD
HHHHCCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCCCCCCCC
QEATAASRESATFTGRIASSTARERTPAKPVEVPPSAYAFGSLLGQGLELSALAMKPRAK
HHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
GYASVSVEQGGSWREGGVSPQPEDRNASKRSCSAARAACWRDLSDHAFFELMPFDESEDW
CCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
VPASFRQVAVKTQAQRSAVPAAARQVRLPVAGASEITSLFRVIECSPPPASDAVNAPLPE
CCHHHHHHHHHHHHHHHHCCHHHHHEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PKAEVRYETSTAATEERIMAADAASRENAARERDRQAAGRVVPFPPAPMKRASAPVVVAP
CCHHEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCEEEEC
RHSLAAGGSYEFPSEELLQNPPEGQGFYMTQEQIEQNAGLLENVLEDFGVRGEIIHVRPG
CCCCCCCCCCCCCCHHHHCCCCCCCCEEECHHHHHHCCCHHHHHHHHCCCCCEEEEECCC
PVVTLYEFEPAPGVKSSRVINLADDIARSMSAVSARVAVVPGRNVIGIELPNVERETVYL
CEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCHHHHHH
RELIQSGDFHKTGYKLALCLGKTIGGEAVIAELAKMPHLLVAGTTGSGKSVAINTMILSL
HHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCEEHHHHHHHHH
LYRLRPEECRLIMVDPKMLELSVYDGIPHLLTPVVTDPKKAVTALKWAVREMEDRYRKMA
HHHCCCCCCEEEEECCCEEEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RLGVRNIDGYNQRAATARDKGEPVLISVQTGFDRSTGEPIYEEQEMDLAPMPYIVVIVDE
HHCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEHHH
MADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTS
HHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCEEEEEEEC
KIDSRTILGEQGAEQLLGQGDMLHMSGGGRIVRVHGPFVSDEEVEQVVAHLKTQGRPEYL
CCCCHHECCHHHHHHHHCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHH
DTVTADEEEEQAPEEDSAVFDKGAIASEDGNEIYDQAVKVVLRDKRCSTSYIQRRLGIGY
HCCCCCCHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
NRAASLIERMEKEGLVGKPNHVGKREILMGGRDVGPSSGDGD
HHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]