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The map label for this gene is rpoC

Identifier: 110634168

GI number: 110634168

Start: 1948092

End: 1952291

Strand: Reverse

Name: rpoC

Synonym: Meso_1818

Alternate gene names: 110634168

Gene position: 1952291-1948092 (Counterclockwise)

Preceding gene: 110634169

Following gene: 110634167

Centisome position: 44.25

GC content: 62.71

Gene sequence:

>4200_bases
ATGAACCAAGAGGTCATGAACCTGTTCAACCCTCAGGCGCCGGCACAGACCTTCGATTCCATCCGGATTTCGCTCGCGAG
TCCGGAGAAGATCCTGTCCTGGTCCTACGGCGAGATCAAAAAGCCGGAAACGATCAACTACCGCACCTTCAAGCCGGAGC
GGGACGGCCTTTTCTGCGCGCGCATCTTCGGCCCGATCAAGGATTATGAGTGCTTGTGCGGCAAGTACAAGCGTATGAAA
TATAAGGGCGTCATCTGCGAGAAGTGCGGCGTGGAAGTGACGCTGTCGCGCGTGCGCCGCGAGCGCATGGGGCATATCGA
ACTCGCCGCGCCCGTTGCCCATATCTGGTTCCTTAAGTCGCTGCCCTCGCGCATCGGCACGCTGCTCGACATGACGCTCA
AGGATATCGAGCGCGTTCTCTATTTCGAGAACTATATCGTGACCGAGCCGGGCCTGACCGCGCTCAAGCAGAACCAGCTC
CTCTCCGAAGAGGAGTACATGATGGCCGTCGACGAGTATGGCGAGGATTCCTTCACCGCCATGATCGGCGCGGAGGCCAT
TCATCACCTGCTCGCCAGCATGGAACTGGAGAAGATCGCCGGCGATCTTCGCTCCGAGCTTGCTTCGACGACTTCGGACC
TGAAGCAGAAGAAGCTTTTGAAGCGGCTGAAGGTCGTGGAGAACTTCCTGGAATCCGGCAACAAGCCGGAGTGGATGGTC
ATGAAGATCATCCCGGTCATTCCGCCGGATCTGCGCCCGCTGGTGCCGCTCGACGGCGGCCGCTTCGCGACCTCGGATCT
CAATGATCTTTACCGCCGCGTCATCAACCGCAACAACCGCCTGAAGCGGCTGATCGAGCTCAAGGCGCCGGGCATCATCA
TTCGCAACGAGAAGCGCATGCTGCAGGAGGCCGTCGACGCTCTGTTCGACAATGGCCGCCGGGGCCGCGTGATCACGGGC
GCCAACAAGCGTCCGCTGAAGTCGCTGTCGGATATGCTGAAGGGCAAGCAGGGCCGCTTCCGGCAGAACCTGCTCGGCAA
GCGCGTCGACTATTCGGGCCGTTCGGTCATCGTGACCGGCCCGGAGCTGAAGCTGCACCAGTGCGGCCTGCCGAAGAAGA
TGGCGCTGGAGCTGTTCAAGCCGTTCATCTATGCGAGGCTTGACGCCAAGGGCTATTCCTCGACGGTCAAGCAGGCCAAG
AAGCTGGTCGAGAAGGAAAAGCCGGAAGTCTGGGATATCCTCGACGAGGTCATCCGTGAGCATCCGGTGCTCCTGAACCG
CGCGCCGACGCTGCACCGGTTGGGCATCCAGGCCTTCGAGCCAATCCTGATAGAGGGCAAGGCGATCCAGCTGCATCCGC
TCGTCTGCACGGCCTTCAACGCCGACTTCGACGGTGACCAGATGGCCGTGCACGTGCCGCTGTCGCTCGAAGCGCAGCTC
GAAGCGCGCGTCCTGATGATGTCCACCAACAACATCCTGCACCCGGCTTCCGGCGCACCGATCATCGTGCCTTCGCAGGA
CATGGTTCTGGGACTCTATTACCTGTCCATCATGAACCAGAACGAGCCGGGCGAGGGGATGGTGTTCGCCGATATGGGCG
AGCTGCAGCATGCGCTGGAGACGAAGGTCGTCACGCTGCACAGCAAGATCAAGGGCCGGTACAAGACCGTGGACGAGAAC
GGCAATCCCGTCTCGATGATCTACGAGACCACGCCTGGCCGGATGATCATCGGCGAGCTTCTGCCGAAGAACCACAATGT
GCCCTTCGACATCTGCAATCAGGAGCTGACCAAGAAGAACATCTCCAAGATGATCGACACGGTCTATCGCCATTGCGGCC
AGAAGGAGACGGTTATCTTCTGCGACCGCATCATGGCGCTGGGCTTCAGCCATGCGTGCAAGGCGGGAATCTCCTTCGGC
AAGGACGATATGGTGATCCCGGAGACGAAGGCGAAGCTGATCGCCGAGACCGAGGCGCTCGCGAAGGAATACGAGCAGCA
GTACAATGACGGTCTGATCACGCAGGGCGAGAAGTACAACAAGGTGGTCGACGCCTGGGCCAAGTGCTCGGAGCGTGTCG
CCGACGAGATGATGAAGCGCATCAAGGCGATCGAGTTCGACGACAGCGGTCGTCAGAAGCAGATGAACTCGATCTATATG
ATGTCGCATTCGGGCGCCCGCGGCTCGCCCGCGCAGATGCGCCAGCTCGCCGGCATGCGCGGCCTGATGGCACGCCCGGA
CGGCTCCATCATCGAGACGCCGATCATCTCGAACTTCAAGGAAGGCCTGACCGTGATGGAGTACTTCAACTCCACCCACG
GCGCACGTAAGGGTCTTGCCGACACCGCGCTGAAGACGGCGAACTCGGGTTACCTGACCCGCCGCCTCGTCGACGTGGCG
CAGGATTGCATCGTGGTCACCCCCGATTGCGGCACCGACAAGGGGCTAACCATGCAGCCCATCGTTGATGCCGGCCAGGT
CGTGGCGTCCATCGGCCAGCGTGTTCTGGGCCGCACGGCGCTTGACGATGTGGTGAATCCGGCCACGGGCGAGGTCATCG
TCCAAGCCGGCCGGCTCATCGATGAGCGGGACGTGGAGGCGATCGAGGCTGCCGGCATCCAGACCGTTCGTATCCGTTCG
GCGCTGACCTGCGAAGTGCGCACGGGCGTCTGCGCGGTCTGCTATGGCCGCGATCTGGCGCGCGGCACGCCTGTCAATAT
CGGCGAGGCTGTCGGCGTTATCGCCGCGCAGTCCATCGGCGAGCCGGGCACGCAGCTCACCATGCGTACCTTCCACATGG
GCGGCACGGCACAGGTCGTGGACCAGTCGTTCCTCGAAGCCTCCTTCGAGGGCACGGTAAAGATCCGCAACCGCAACGTG
GTGCGCAACTCGGACGGCCATCTCGTCGTCATGGGCCGCAACATGGCAGTGCTGATCCTGGACGAAGCAGGCGCGGAGCG
TGCGTCGCACAAGGTCACCTATGGTTCGCGCATCTTCGTGGACGATGGCGACAAGGTGAAGCGCGGCCAGCGCATCGCCG
AGTGGGACCCGTACACCCGCCCGATGCTGACGGAAGTGGAAGGCACAGTGGCCTTCGAGGATCTGGTGGACGGCATCTCC
GTGCAGGAGACGACCGACGAATCCACCGGCATCACCAAGCGCGAGGTCATCGACTGGCGGTCCACGCCGCGCGGTTCGGA
CCTGAAGCCGGCGATCACGATCCTCGACTCCAAGGGCAAGGTGGCAAAGCTCGCCCGTGGCGGCGATGCCCGCTTCCTGC
TCTCGGTGGAGACGGTTCTGTCGGTGGATTCGGGCGCGAAGGTCAGGCCGGGCGACGTTGTGGCCCGTATCCCGACCGAA
AGCGCGCGCACCAAGGACATCACCGGTGGTCTGCCGCGTGTGGCCGAGCTCTTCGAAGCGCGGCGCCCGAAGGACCATGC
CATCATCGCTGAGATCGACGGTACGGTGCGTTTCGGCCGCGACTACAAGAACAAGCGCCGCATCATCATCGAGCCGCATG
ACTCCACTTTGGAGCCGGTGGAGTATCTCATCCCGAAGGGCAAGCCGTTCCACCTGCAGGACGGCGACGTCATCGAGAAG
GGCGACTTCATCCTCGACGGCAATCCGGCGCCGCACGACATCCTGGCGATCAAGGGCGTGGAGGCGCTGGCCTCCTACCT
CGTCAACGAGATCCAGGAAGTCTACCGGCTCCAGGGCGTGTTGATCAACGACAAGCACATCGAGGTGATCGTCCGCCAGA
TGCTGCAGAAGGTCGAGATCACGGCTCAGGGCGATTCGACCTACATCCCCGGCGACCACGTGGATCAGGTCGAGTTTGAC
GAGGTGAACGACCGCTTGGTGGAAGAGGGCAAGAAGCCTGCGGAAGGCCAGCCGGTGCTGCTCGGCATCACCAAGGCCTC
GCTGCAGACGCCGTCCTTCATCTCCGCCGCCTCCTTCCAGGAGACGACGCGCGTGCTGACCGAGGCCGCTGTCGCGGGCA
AGATCGATACGCTGCAGGGCCTGAAGGAGAACGTCATCGTCGGCCGCCTCATCCCGGCAGGCACCGGCGGCGCCATGGCG
CAGATCCGGCGCATTGCCCGCTCGCGCGACGATCTCATCCTCGACGAGCGGCGCAAGGAATCGGGCGTGGAAATGGCCAA
TCCCGCCATTGCCGACATGGCCGGACAGCCGGCCGAGTAA

Upstream 100 bases:

>100_bases
CCCCTGATGGAAGGGCTTTCGCGACACGAGGCTCGCTAGCCGCCGGAAGCCGCCATCGCACTGTGATTAAGGGACGCGAA
GTCCCGTAAAGGAGATCGGC

Downstream 100 bases:

>100_bases
GCGCAGGCACCAGCATCGAAAAAAGCCGCCGGTTTTCGCCGGCGGCTTTTTTGTGCAACAACAGAACCGAAATTCGATTA
ACCAATTTCATTATTTGAGT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1399; Mature: 1399

Protein sequence:

>1399_residues
MNQEVMNLFNPQAPAQTFDSIRISLASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGVICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTALKQNQL
LSEEEYMMAVDEYGEDSFTAMIGAEAIHHLLASMELEKIAGDLRSELASTTSDLKQKKLLKRLKVVENFLESGNKPEWMV
MKIIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELKAPGIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPASGAPIIVPSQDMVLGLYYLSIMNQNEPGEGMVFADMGELQHALETKVVTLHSKIKGRYKTVDEN
GNPVSMIYETTPGRMIIGELLPKNHNVPFDICNQELTKKNISKMIDTVYRHCGQKETVIFCDRIMALGFSHACKAGISFG
KDDMVIPETKAKLIAETEALAKEYEQQYNDGLITQGEKYNKVVDAWAKCSERVADEMMKRIKAIEFDDSGRQKQMNSIYM
MSHSGARGSPAQMRQLAGMRGLMARPDGSIIETPIISNFKEGLTVMEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIVVTPDCGTDKGLTMQPIVDAGQVVASIGQRVLGRTALDDVVNPATGEVIVQAGRLIDERDVEAIEAAGIQTVRIRS
ALTCEVRTGVCAVCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHMGGTAQVVDQSFLEASFEGTVKIRNRNV
VRNSDGHLVVMGRNMAVLILDEAGAERASHKVTYGSRIFVDDGDKVKRGQRIAEWDPYTRPMLTEVEGTVAFEDLVDGIS
VQETTDESTGITKREVIDWRSTPRGSDLKPAITILDSKGKVAKLARGGDARFLLSVETVLSVDSGAKVRPGDVVARIPTE
SARTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPHDSTLEPVEYLIPKGKPFHLQDGDVIEK
GDFILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITAQGDSTYIPGDHVDQVEFD
EVNDRLVEEGKKPAEGQPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKIDTLQGLKENVIVGRLIPAGTGGAMA
QIRRIARSRDDLILDERRKESGVEMANPAIADMAGQPAE

Sequences:

>Translated_1399_residues
MNQEVMNLFNPQAPAQTFDSIRISLASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGVICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTALKQNQL
LSEEEYMMAVDEYGEDSFTAMIGAEAIHHLLASMELEKIAGDLRSELASTTSDLKQKKLLKRLKVVENFLESGNKPEWMV
MKIIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELKAPGIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPASGAPIIVPSQDMVLGLYYLSIMNQNEPGEGMVFADMGELQHALETKVVTLHSKIKGRYKTVDEN
GNPVSMIYETTPGRMIIGELLPKNHNVPFDICNQELTKKNISKMIDTVYRHCGQKETVIFCDRIMALGFSHACKAGISFG
KDDMVIPETKAKLIAETEALAKEYEQQYNDGLITQGEKYNKVVDAWAKCSERVADEMMKRIKAIEFDDSGRQKQMNSIYM
MSHSGARGSPAQMRQLAGMRGLMARPDGSIIETPIISNFKEGLTVMEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIVVTPDCGTDKGLTMQPIVDAGQVVASIGQRVLGRTALDDVVNPATGEVIVQAGRLIDERDVEAIEAAGIQTVRIRS
ALTCEVRTGVCAVCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHMGGTAQVVDQSFLEASFEGTVKIRNRNV
VRNSDGHLVVMGRNMAVLILDEAGAERASHKVTYGSRIFVDDGDKVKRGQRIAEWDPYTRPMLTEVEGTVAFEDLVDGIS
VQETTDESTGITKREVIDWRSTPRGSDLKPAITILDSKGKVAKLARGGDARFLLSVETVLSVDSGAKVRPGDVVARIPTE
SARTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPHDSTLEPVEYLIPKGKPFHLQDGDVIEK
GDFILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITAQGDSTYIPGDHVDQVEFD
EVNDRLVEEGKKPAEGQPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKIDTLQGLKENVIVGRLIPAGTGGAMA
QIRRIARSRDDLILDERRKESGVEMANPAIADMAGQPAE
>Mature_1399_residues
MNQEVMNLFNPQAPAQTFDSIRISLASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMK
YKGVICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTALKQNQL
LSEEEYMMAVDEYGEDSFTAMIGAEAIHHLLASMELEKIAGDLRSELASTTSDLKQKKLLKRLKVVENFLESGNKPEWMV
MKIIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELKAPGIIIRNEKRMLQEAVDALFDNGRRGRVITG
ANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAK
KLVEKEKPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
EARVLMMSTNNILHPASGAPIIVPSQDMVLGLYYLSIMNQNEPGEGMVFADMGELQHALETKVVTLHSKIKGRYKTVDEN
GNPVSMIYETTPGRMIIGELLPKNHNVPFDICNQELTKKNISKMIDTVYRHCGQKETVIFCDRIMALGFSHACKAGISFG
KDDMVIPETKAKLIAETEALAKEYEQQYNDGLITQGEKYNKVVDAWAKCSERVADEMMKRIKAIEFDDSGRQKQMNSIYM
MSHSGARGSPAQMRQLAGMRGLMARPDGSIIETPIISNFKEGLTVMEYFNSTHGARKGLADTALKTANSGYLTRRLVDVA
QDCIVVTPDCGTDKGLTMQPIVDAGQVVASIGQRVLGRTALDDVVNPATGEVIVQAGRLIDERDVEAIEAAGIQTVRIRS
ALTCEVRTGVCAVCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHMGGTAQVVDQSFLEASFEGTVKIRNRNV
VRNSDGHLVVMGRNMAVLILDEAGAERASHKVTYGSRIFVDDGDKVKRGQRIAEWDPYTRPMLTEVEGTVAFEDLVDGIS
VQETTDESTGITKREVIDWRSTPRGSDLKPAITILDSKGKVAKLARGGDARFLLSVETVLSVDSGAKVRPGDVVARIPTE
SARTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPHDSTLEPVEYLIPKGKPFHLQDGDVIEK
GDFILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITAQGDSTYIPGDHVDQVEFD
EVNDRLVEEGKKPAEGQPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKIDTLQGLKENVIVGRLIPAGTGGAMA
QIRRIARSRDDLILDERRKESGVEMANPAIADMAGQPAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=606, Percent_Identity=26.5676567656766, Blast_Score=155, Evalue=4e-37,
Organism=Homo sapiens, GI39725938, Length=664, Percent_Identity=26.2048192771084, Blast_Score=153, Evalue=9e-37,
Organism=Homo sapiens, GI103471997, Length=250, Percent_Identity=31.2, Blast_Score=92, Evalue=4e-18,
Organism=Escherichia coli, GI2367335, Length=1373, Percent_Identity=60.6700655498908, Blast_Score=1683, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=915, Percent_Identity=24.2622950819672, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25145495, Length=309, Percent_Identity=32.0388349514563, Blast_Score=137, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320061, Length=892, Percent_Identity=23.542600896861, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=709, Percent_Identity=25.8110014104372, Blast_Score=156, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324917, Length=616, Percent_Identity=25.1623376623377, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281360912, Length=848, Percent_Identity=25, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17530899, Length=489, Percent_Identity=26.5848670756646, Blast_Score=150, Evalue=9e-36,
Organism=Drosophila melanogaster, GI17647875, Length=357, Percent_Identity=26.3305322128852, Blast_Score=103, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_MESSB (Q11HB4)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_674376.1
- ProteinModelPortal:   Q11HB4
- STRING:   Q11HB4
- GeneID:   4181523
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1818
- NMPDR:   fig|266779.1.peg.3757
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q11HB4
- ProtClustDB:   PRK00566
- BioCyc:   MSP266779:MESO_1818-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155034; Mature: 155034

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEVMNLFNPQAPAQTFDSIRISLASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCHHHHHHEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGVICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTALKQNQLLSEEEYMMAVDEYGEDSFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHH
MIGAEAIHHLLASMELEKIAGDLRSELASTTSDLKQKKLLKRLKVVENFLESGNKPEWMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKIIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELKAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEKPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEEECCEEEEEEEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPASGAPIIVPSQDMVLGLYYLSIMNQNEPGEGMVFADMGELQHALE
CEEEEEEECCCEECCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
TKVVTLHSKIKGRYKTVDENGNPVSMIYETTPGRMIIGELLPKNHNVPFDICNQELTKKN
HHHEEEHHHHCCCEEEECCCCCEEEEEEECCCCCEEHHHHCCCCCCCCHHHHHHHHHHHH
ISKMIDTVYRHCGQKETVIFCDRIMALGFSHACKAGISFGKDDMVIPETKAKLIAETEAL
HHHHHHHHHHHCCCCCEEHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
AKEYEQQYNDGLITQGEKYNKVVDAWAKCSERVADEMMKRIKAIEFDDSGRQKQMNSIYM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHCCEEEE
MSHSGARGSPAQMRQLAGMRGLMARPDGSIIETPIISNFKEGLTVMEYFNSTHGARKGLA
EECCCCCCCHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHH
DTALKTANSGYLTRRLVDVAQDCIVVTPDCGTDKGLTMQPIVDAGQVVASIGQRVLGRTA
HHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
LDDVVNPATGEVIVQAGRLIDERDVEAIEAAGIQTVRIRSALTCEVRTGVCAVCYGRDLA
HHHHCCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEECCEEEEEECCCEEEEECCCHHC
RGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHMGGTAQVVDQSFLEASFEGTVKIRNRNV
CCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCE
VRNSDGHLVVMGRNMAVLILDEAGAERASHKVTYGSRIFVDDGDKVKRGQRIAEWDPYTR
EECCCCEEEEEECCEEEEEEECCCCCHHCCEEECCCEEEECCCHHHHHCCCCCCCCCCCC
PMLTEVEGTVAFEDLVDGISVQETTDESTGITKREVIDWRSTPRGSDLKPAITILDSKGK
CHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECCCCC
VAKLARGGDARFLLSVETVLSVDSGAKVRPGDVVARIPTESARTKDITGGLPRVAELFEA
EEHHHCCCCCEEEEEEEHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
RRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPHDSTLEPVEYLIPKGKPFHLQDGDVIEK
CCCCCCEEEEEECCCEEECCCCCCCCEEEECCCCCCCCHHHHHCCCCCEEECCCCCEEEC
GDFILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEI
CCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCEE
TAQGDSTYIPGDHVDQVEFDEVNDRLVEEGKKPAEGQPVLLGITKASLQTPSFISAASFQ
EECCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHHH
ETTRVLTEAAVAGKIDTLQGLKENVIVGRLIPAGTGGAMAQIRRIARSRDDLILDERRKE
HHHHHHHHHHHHCCHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHH
SGVEMANPAIADMAGQPAE
CCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MNQEVMNLFNPQAPAQTFDSIRISLASPEKILSWSYGEIKKPETINYRTFKPERDGLFCA
CCHHHHHHCCCCCCHHHHHHEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEE
RIFGPIKDYECLCGKYKRMKYKGVICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKS
HHHCCCCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
LPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTALKQNQLLSEEEYMMAVDEYGEDSFTA
HHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHH
MIGAEAIHHLLASMELEKIAGDLRSELASTTSDLKQKKLLKRLKVVENFLESGNKPEWMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
MKIIPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELKAPGIIIRNEKRM
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHH
LQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTG
HHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEC
PELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKEKPEVWDILDEVIRE
CCEEEHHCCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQL
CCEEECCCCCHHHHCHHHCCCEEEECCEEEEEEEEEEEECCCCCCCCEEEEECCEECCCC
EARVLMMSTNNILHPASGAPIIVPSQDMVLGLYYLSIMNQNEPGEGMVFADMGELQHALE
CEEEEEEECCCEECCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHH
TKVVTLHSKIKGRYKTVDENGNPVSMIYETTPGRMIIGELLPKNHNVPFDICNQELTKKN
HHHEEEHHHHCCCEEEECCCCCEEEEEEECCCCCEEHHHHCCCCCCCCHHHHHHHHHHHH
ISKMIDTVYRHCGQKETVIFCDRIMALGFSHACKAGISFGKDDMVIPETKAKLIAETEAL
HHHHHHHHHHHCCCCCEEHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
AKEYEQQYNDGLITQGEKYNKVVDAWAKCSERVADEMMKRIKAIEFDDSGRQKQMNSIYM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHCCEEEE
MSHSGARGSPAQMRQLAGMRGLMARPDGSIIETPIISNFKEGLTVMEYFNSTHGARKGLA
EECCCCCCCHHHHHHHHCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHH
DTALKTANSGYLTRRLVDVAQDCIVVTPDCGTDKGLTMQPIVDAGQVVASIGQRVLGRTA
HHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHH
LDDVVNPATGEVIVQAGRLIDERDVEAIEAAGIQTVRIRSALTCEVRTGVCAVCYGRDLA
HHHHCCCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEECCEEEEEECCCEEEEECCCHHC
RGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHMGGTAQVVDQSFLEASFEGTVKIRNRNV
CCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCE
VRNSDGHLVVMGRNMAVLILDEAGAERASHKVTYGSRIFVDDGDKVKRGQRIAEWDPYTR
EECCCCEEEEEECCEEEEEEECCCCCHHCCEEECCCEEEECCCHHHHHCCCCCCCCCCCC
PMLTEVEGTVAFEDLVDGISVQETTDESTGITKREVIDWRSTPRGSDLKPAITILDSKGK
CHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECCCCC
VAKLARGGDARFLLSVETVLSVDSGAKVRPGDVVARIPTESARTKDITGGLPRVAELFEA
EEHHHCCCCCEEEEEEEHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
RRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPHDSTLEPVEYLIPKGKPFHLQDGDVIEK
CCCCCCEEEEEECCCEEECCCCCCCCEEEECCCCCCCCHHHHHCCCCCEEECCCCCEEEC
GDFILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEI
CCEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHCEE
TAQGDSTYIPGDHVDQVEFDEVNDRLVEEGKKPAEGQPVLLGITKASLQTPSFISAASFQ
EECCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCHHHHHHHH
ETTRVLTEAAVAGKIDTLQGLKENVIVGRLIPAGTGGAMAQIRRIARSRDDLILDERRKE
HHHHHHHHHHHHCCHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHH
SGVEMANPAIADMAGQPAE
CCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA