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The map label for this gene is argS

Identifier: 110634164

GI number: 110634164

Start: 1943710

End: 1945467

Strand: Reverse

Name: argS

Synonym: Meso_1813

Alternate gene names: 110634164

Gene position: 1945467-1943710 (Counterclockwise)

Preceding gene: 110634165

Following gene: 110634163

Centisome position: 44.09

GC content: 60.01

Gene sequence:

>1758_bases
ATGAACATTTTTGCCGATTTTTCCGATCGGATCATCAACGCCGTGAAGGCACTGGAGCTGAAGCCGAAGGAAGGCGGAGA
GCTCGATCTGTCGCGTGTTGCCGTCGAGCCGCCGCGCGATCCGAGCCATGGCGACATCGCAACCAATGCGGCAATGGTGC
TGTCGAAGGCGGTTGGCGAAAATCCGCGCGCCCTTGGAGAGCGGCTTGCTGCTGCCCTGGCCGAGGATCCTGACGTGGCC
GAGGCGAGCGTGGCCGGCCCGGGATTCGTCAATTTGAGGCTCGGAAATGGCTTCTGGCATGCGCGGCTCGGCGAGATGCT
GCTTCTGGCCGGCGACTACGGGCGCTCGAAAATGGGCAACGGGCACAAGGTCAATGTCGAATATGTCTCGGCCAATCCGA
CCGGGCCGATGCATGTGGGCCACTGCCGCGGCGCCGTTGTCGGGGATGCGCTTTCCAATCTCCTTGCCTTTGCCGGCTAT
GATGTGACGCGGGAATACTACATCAACGATGCGGGCGCGCAGATCGACGTGCTCGGGCGTTCCGTCCTCATGCGCTATAG
GGAGGCGCTGGGCGAGGATATCGGCCAGATTCCCGAAGGGCTCTATCCCGGCGACTACCTCAAGCCGGTGGGCAAGGCGC
TCGCGGATGAATATGGCACCAAGCTTCTGGAAAGGCCGGCCGAAGAAGCGCTGAAAATCGCGAAGGACACGGCGATCGAC
GCCATGATGGCCATGATCCGCGAGGATCTGGCCGCGCTCAACGTGCACCATGACGTGTTCTTCTCCGAGCGCTCGCTGCA
CGCCGGCAATGGCGGGACCATCCGCTCGGCGATCAACGACCTGACGCTGAAGGGCCATGTCTACAAAGGCAAGCTGCCGC
CGCCCAAGGGCCAGGTTCTCGAGGATTGGGAGGACCGGGAGCAGACGCTCTTCCGGTCCACCGATGTCGGGGATGATATC
GACCGGCCCTTGATCAAGTCGGATGGCACATTCACCTATTTCGCCGCCGATGTGGCCTATATGAAGGATAAATATAGCCG
GGGTTTTGAGCACCTGATCTATGTGCTGGGCGCGGACCATGGCGGGTATGTGAAGCGCCTGGAGGCGCTCGCCCGGGCCA
TTTCCGAGGGCAAACTGCATCTGACCGTGCTGCTCTGCCAGCTCGTCAAGCTTTTCCGCAACGGCGAGCCGGTGCGCATG
TCCAAGCGGGCCGGTGAATTCGTAACGCTGCGCGACGTGATCGATGAAGTCGGCCGCGATGCGGTGCGCTTCATGATGCT
GTACCGGAAGAGCGATGCGCCGCTGGACTTCGATTTCGCGAAGGTGACAGAACAGTCGAAGGATAACCCCGTCTTTTATG
TCCAGTATGCTTCCGCCCGCTGTCATTCTGTCTTCCGCCAGGCGAGCGAGCAACTGAACGTCAGAAAATTCGACCGCGAA
GCGATGAAGGCGGCCTTGCATCGGCTGGACGATCCAGGTGAAATCGCCTTGATACGCAAGCTTGCCGAGTATCCGAGGCT
GATAGAAAGCGCGGCACAGGCGCTGGAGCCGCACAGGCTTGCTTTTTATTTGTATGAACTTGCCAACCAGTTCCATGTGC
AATGGAATCGTGGTAGCGAGACAGATCGCTTACGTTTTGTTAAAGTTAACGACCCAGAGTTGACACATGCCAGGCTGGGT
CTGGTGCAGGCTGTTTGTGATGTCGTGCGGTCGGGACTGGCGCTCGTAGGAGCAGATGCCCCAGAGGAGATGCGATAA

Upstream 100 bases:

>100_bases
CGAACGCCTATTTGACCGCACCCCGGATTTGCGTTAGGCGCAGGCGGCTGGCTCGCGGCCAGACGCCGCAGCACCGAAAT
TAATTTCCAGGACCGGGTCC

Downstream 100 bases:

>100_bases
TCACAGACAATACTGTCACCTTTTGCCCACATTGCCCTGGTAGGGCCAATAGAAGCGAGACGTGCCGGCGTCCGACCGGG
GTGTGGGAAGATGGCTGATA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MNIFADFSDRIINAVKALELKPKEGGELDLSRVAVEPPRDPSHGDIATNAAMVLSKAVGENPRALGERLAAALAEDPDVA
EASVAGPGFVNLRLGNGFWHARLGEMLLLAGDYGRSKMGNGHKVNVEYVSANPTGPMHVGHCRGAVVGDALSNLLAFAGY
DVTREYYINDAGAQIDVLGRSVLMRYREALGEDIGQIPEGLYPGDYLKPVGKALADEYGTKLLERPAEEALKIAKDTAID
AMMAMIREDLAALNVHHDVFFSERSLHAGNGGTIRSAINDLTLKGHVYKGKLPPPKGQVLEDWEDREQTLFRSTDVGDDI
DRPLIKSDGTFTYFAADVAYMKDKYSRGFEHLIYVLGADHGGYVKRLEALARAISEGKLHLTVLLCQLVKLFRNGEPVRM
SKRAGEFVTLRDVIDEVGRDAVRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLNVRKFDRE
AMKAALHRLDDPGEIALIRKLAEYPRLIESAAQALEPHRLAFYLYELANQFHVQWNRGSETDRLRFVKVNDPELTHARLG
LVQAVCDVVRSGLALVGADAPEEMR

Sequences:

>Translated_585_residues
MNIFADFSDRIINAVKALELKPKEGGELDLSRVAVEPPRDPSHGDIATNAAMVLSKAVGENPRALGERLAAALAEDPDVA
EASVAGPGFVNLRLGNGFWHARLGEMLLLAGDYGRSKMGNGHKVNVEYVSANPTGPMHVGHCRGAVVGDALSNLLAFAGY
DVTREYYINDAGAQIDVLGRSVLMRYREALGEDIGQIPEGLYPGDYLKPVGKALADEYGTKLLERPAEEALKIAKDTAID
AMMAMIREDLAALNVHHDVFFSERSLHAGNGGTIRSAINDLTLKGHVYKGKLPPPKGQVLEDWEDREQTLFRSTDVGDDI
DRPLIKSDGTFTYFAADVAYMKDKYSRGFEHLIYVLGADHGGYVKRLEALARAISEGKLHLTVLLCQLVKLFRNGEPVRM
SKRAGEFVTLRDVIDEVGRDAVRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLNVRKFDRE
AMKAALHRLDDPGEIALIRKLAEYPRLIESAAQALEPHRLAFYLYELANQFHVQWNRGSETDRLRFVKVNDPELTHARLG
LVQAVCDVVRSGLALVGADAPEEMR
>Mature_585_residues
MNIFADFSDRIINAVKALELKPKEGGELDLSRVAVEPPRDPSHGDIATNAAMVLSKAVGENPRALGERLAAALAEDPDVA
EASVAGPGFVNLRLGNGFWHARLGEMLLLAGDYGRSKMGNGHKVNVEYVSANPTGPMHVGHCRGAVVGDALSNLLAFAGY
DVTREYYINDAGAQIDVLGRSVLMRYREALGEDIGQIPEGLYPGDYLKPVGKALADEYGTKLLERPAEEALKIAKDTAID
AMMAMIREDLAALNVHHDVFFSERSLHAGNGGTIRSAINDLTLKGHVYKGKLPPPKGQVLEDWEDREQTLFRSTDVGDDI
DRPLIKSDGTFTYFAADVAYMKDKYSRGFEHLIYVLGADHGGYVKRLEALARAISEGKLHLTVLLCQLVKLFRNGEPVRM
SKRAGEFVTLRDVIDEVGRDAVRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLNVRKFDRE
AMKAALHRLDDPGEIALIRKLAEYPRLIESAAQALEPHRLAFYLYELANQFHVQWNRGSETDRLRFVKVNDPELTHARLG
LVQAVCDVVRSGLALVGADAPEEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=149, Percent_Identity=33.5570469798658, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI1788184, Length=579, Percent_Identity=23.3160621761658, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71985061, Length=157, Percent_Identity=29.2993630573248, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71985068, Length=157, Percent_Identity=29.2993630573248, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320548, Length=572, Percent_Identity=25.3496503496504, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321883, Length=603, Percent_Identity=22.2222222222222, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_MESSB (Q11HB8)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_674372.1
- ProteinModelPortal:   Q11HB8
- STRING:   Q11HB8
- GeneID:   4181519
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1813
- NMPDR:   fig|266779.1.peg.3753
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   MSP266779:MESO_1813-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64751; Mature: 64751

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFADFSDRIINAVKALELKPKEGGELDLSRVAVEPPRDPSHGDIATNAAMVLSKAVGE
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHCC
NPRALGERLAAALAEDPDVAEASVAGPGFVNLRLGNGFWHARLGEMLLLAGDYGRSKMGN
CHHHHHHHHHHHHCCCCCCCHHCCCCCCEEEEEECCCCHHHHHCCEEEEECCCCCCCCCC
GHKVNVEYVSANPTGPMHVGHCRGAVVGDALSNLLAFAGYDVTREYYINDAGAQIDVLGR
CCEEEEEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEHHHHH
SVLMRYREALGEDIGQIPEGLYPGDYLKPVGKALADEYGTKLLERPAEEALKIAKDTAID
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMMAMIREDLAALNVHHDVFFSERSLHAGNGGTIRSAINDLTLKGHVYKGKLPPPKGQVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCEEECEEEECCCCCCCCCHH
EDWEDREQTLFRSTDVGDDIDRPLIKSDGTFTYFAADVAYMKDKYSRGFEHLIYVLGADH
HCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHHHEEEEEECCC
GGYVKRLEALARAISEGKLHLTVLLCQLVKLFRNGEPVRMSKRAGEFVTLRDVIDEVGRD
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHCCCEEEHHHHHHHHHHH
AVRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLNVRKFDRE
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHH
AMKAALHRLDDPGEIALIRKLAEYPRLIESAAQALEPHRLAFYLYELANQFHVQWNRGSE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCC
TDRLRFVKVNDPELTHARLGLVQAVCDVVRSGLALVGADAPEEMR
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure
MNIFADFSDRIINAVKALELKPKEGGELDLSRVAVEPPRDPSHGDIATNAAMVLSKAVGE
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHCC
NPRALGERLAAALAEDPDVAEASVAGPGFVNLRLGNGFWHARLGEMLLLAGDYGRSKMGN
CHHHHHHHHHHHHCCCCCCCHHCCCCCCEEEEEECCCCHHHHHCCEEEEECCCCCCCCCC
GHKVNVEYVSANPTGPMHVGHCRGAVVGDALSNLLAFAGYDVTREYYINDAGAQIDVLGR
CCEEEEEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEHHHHH
SVLMRYREALGEDIGQIPEGLYPGDYLKPVGKALADEYGTKLLERPAEEALKIAKDTAID
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMMAMIREDLAALNVHHDVFFSERSLHAGNGGTIRSAINDLTLKGHVYKGKLPPPKGQVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCEEECEEEECCCCCCCCCHH
EDWEDREQTLFRSTDVGDDIDRPLIKSDGTFTYFAADVAYMKDKYSRGFEHLIYVLGADH
HCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCHHHEEEEEECCC
GGYVKRLEALARAISEGKLHLTVLLCQLVKLFRNGEPVRMSKRAGEFVTLRDVIDEVGRD
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEHHHCCCEEEHHHHHHHHHHH
AVRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLNVRKFDRE
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHCCHHHHHHH
AMKAALHRLDDPGEIALIRKLAEYPRLIESAAQALEPHRLAFYLYELANQFHVQWNRGSE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCC
TDRLRFVKVNDPELTHARLGLVQAVCDVVRSGLALVGADAPEEMR
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA