Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 110634123

GI number: 110634123

Start: 1894189

End: 1894965

Strand: Direct

Name: ppnK [H]

Synonym: Meso_1772

Alternate gene names: 110634123

Gene position: 1894189-1894965 (Clockwise)

Preceding gene: 110634113

Following gene: 110634124

Centisome position: 42.93

GC content: 58.69

Gene sequence:

>777_bases
ATGAACAAGCTCTCCTCGCTAGCCCTTGCCTTCGTTTCGGCCGAGACCGAAGACGCGACCACGGCCGCCGCGACGCTTTC
CGCCCTTTATGGGCAGGAGAGGCCGGAGGACGCCGATGTGATTGTCGCGCTTGGGGGCGATGGCTTCATGTTGAAGACAT
TGCGCGAGACCATGGGCACCGGCAAGAAGATCTATGGCATGAACCGCGGCACGGTCGGTTTCCTTATGAACGAGTACCGT
GAAGATGGCCTGCATGAACGCATCGCCGAGGCCATCGCGGAAACCGTTCGCCCGCTGGAAATGACGGCGATCGATCAAAA
CGGGGAGATTTTCCGGGCTCTTGCCATCAATGAGGTATCGCTTCTGCGTCAATCCTATCAGGCTGCAAAGATCCGCATCG
CCATAGACGGCAACGTGCGGCTGGAGGAGCTTATCTGTGACGGGATCATGGTTGCGACCCCGGCGGGTTCGACAGCCTAT
AATCTCTCGGCGCATGGCCCGATCCTGCCACTCGATGCGCCTCTTCTGGCCCTGACGCCCGTGAGCCCGTTTCGCCCGAG
ACGTTGGCGGGGGGCGCTTCTGCCCAACAAGTCGAATGTGGAGCTCACAATACTTGAACCCGAAAAGCGGCCGGTCAACG
CAGTGGCCGATCATACGGAAATCAAGTCCGTTCGTAAGGTAACGGTGCAGGAATCCCTTGATATGACCGCGACGATCCTT
TTCGATGCCAGCCATTCGTGGAATGAGCGCATCCTGTCGGAACAATTCCGCTACTAG

Upstream 100 bases:

>100_bases
CCTGCGCGCTCACCAAAAGCTCTTCTCTCAGCCGCTTTGCACCGCCTCGTGAGCGTGCTACCACCCGTGGGCCATGCCCC
AGAACGGGACGCGAACTTGG

Downstream 100 bases:

>100_bases
CCAATTCTTGCCGTATGAAGGGACGCGGCGAAAAACAGCGCCTGCGGTGCAATACTTGTTGTTGACATCGGCCGCACCAC
ACCTTAGGCCCCGATCACAG

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MNKLSSLALAFVSAETEDATTAAATLSALYGQERPEDADVIVALGGDGFMLKTLRETMGTGKKIYGMNRGTVGFLMNEYR
EDGLHERIAEAIAETVRPLEMTAIDQNGEIFRALAINEVSLLRQSYQAAKIRIAIDGNVRLEELICDGIMVATPAGSTAY
NLSAHGPILPLDAPLLALTPVSPFRPRRWRGALLPNKSNVELTILEPEKRPVNAVADHTEIKSVRKVTVQESLDMTATIL
FDASHSWNERILSEQFRY

Sequences:

>Translated_258_residues
MNKLSSLALAFVSAETEDATTAAATLSALYGQERPEDADVIVALGGDGFMLKTLRETMGTGKKIYGMNRGTVGFLMNEYR
EDGLHERIAEAIAETVRPLEMTAIDQNGEIFRALAINEVSLLRQSYQAAKIRIAIDGNVRLEELICDGIMVATPAGSTAY
NLSAHGPILPLDAPLLALTPVSPFRPRRWRGALLPNKSNVELTILEPEKRPVNAVADHTEIKSVRKVTVQESLDMTATIL
FDASHSWNERILSEQFRY
>Mature_258_residues
MNKLSSLALAFVSAETEDATTAAATLSALYGQERPEDADVIVALGGDGFMLKTLRETMGTGKKIYGMNRGTVGFLMNEYR
EDGLHERIAEAIAETVRPLEMTAIDQNGEIFRALAINEVSLLRQSYQAAKIRIAIDGNVRLEELICDGIMVATPAGSTAY
NLSAHGPILPLDAPLLALTPVSPFRPRRWRGALLPNKSNVELTILEPEKRPVNAVADHTEIKSVRKVTVQESLDMTATIL
FDASHSWNERILSEQFRY

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=156, Percent_Identity=34.6153846153846, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325068, Length=191, Percent_Identity=32.4607329842932, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 28341; Mature: 28341

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLSSLALAFVSAETEDATTAAATLSALYGQERPEDADVIVALGGDGFMLKTLRETMGT
CCCHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
GKKIYGMNRGTVGFLMNEYREDGLHERIAEAIAETVRPLEMTAIDQNGEIFRALAINEVS
CCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEHHHHHH
LLRQSYQAAKIRIAIDGNVRLEELICDGIMVATPAGSTAYNLSAHGPILPLDAPLLALTP
HHHHHHCEEEEEEEECCCCCHHHHHHCCEEEECCCCCCEEEECCCCCEEECCCCEEEECC
VSPFRPRRWRGALLPNKSNVELTILEPEKRPVNAVADHTEIKSVRKVTVQESLDMTATIL
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
FDASHSWNERILSEQFRY
EECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNKLSSLALAFVSAETEDATTAAATLSALYGQERPEDADVIVALGGDGFMLKTLRETMGT
CCCHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
GKKIYGMNRGTVGFLMNEYREDGLHERIAEAIAETVRPLEMTAIDQNGEIFRALAINEVS
CCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEHHHHHH
LLRQSYQAAKIRIAIDGNVRLEELICDGIMVATPAGSTAYNLSAHGPILPLDAPLLALTP
HHHHHHCEEEEEEEECCCCCHHHHHHCCEEEECCCCCCEEEECCCCCEEECCCCEEEECC
VSPFRPRRWRGALLPNKSNVELTILEPEKRPVNAVADHTEIKSVRKVTVQESLDMTATIL
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
FDASHSWNERILSEQFRY
EECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]