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The map label for this gene is yheS [H]

Identifier: 110634105

GI number: 110634105

Start: 1872932

End: 1874809

Strand: Direct

Name: yheS [H]

Synonym: Meso_1754

Alternate gene names: 110634105

Gene position: 1872932-1874809 (Clockwise)

Preceding gene: 110634104

Following gene: 110634108

Centisome position: 42.45

GC content: 64.16

Gene sequence:

>1878_bases
ATGCTGAACATCAATGATCTCTCGCTCCGCGTTGCAGGCCGGCTCCTCATCGAGCAGGCCTCCTTGACGCTGCCCGCCGG
CACGAAAGCCGGCCTTGTCGGCCGAAACGGCACCGGCAAGACGACGCTTTTCCGCGCCATCACGGGCGAGCTTTCGCCGG
AAACGGGCTCGATCAGCCTGCCGAAGGGCACGCGCATCGGCCAGGTGGCACAGGAGGCCCCCGGCACCGAGGAGCCGCTG
ATCGACATAGTGCTCAAGGCCGATACCGAGCGCGACCGGCTGATGCGGGAGGCAGAGACGGCCGAGGACCCGCACCGCAT
CGCCGAGATTCAAACCCGGCTTGCCGATATTGACGCCCATTCCGCGGAGGCACGCGCCGCGGCGATCCTAGCCGGCCTTG
GCTTCGGTCCGGCAGCACAGAAGCGCCCAGCCTCCTCCTTTTCCGGCGGCTGGCGTATGCGTGTGGCGCTCGCGGCGGTG
CTCTTCGCCGAGCCCGATCTCCTGCTTCTCGACGAGCCCACCAACTATCTCGACCTCGAAGGCACGCTCTGGCTGGAAGG
CTACCTGGCGAAATATCCCTACACGGTGCTGCTCATCAGCCACGACCGCGACCTCCTGAACCATGCGGTCAACAACATCG
TGCATCTGGAGGGGAAGAAGCTCACCTTCTGGCGCGGCGGTTATGACCAGTTCGCCCGGCAATATGCCGAAAAGGCCGAA
TTGCAGGAAAAGATGCGCACCAAGCAGGAAGCGCAGAAGAAGCATATGGAAGCCTTTGTGGAGCGCTTCCGGGCCAAGGC
GTCCAAAGCGCGGCAGGCGCAATCGCGCCTGAAAGCGTTGGAGCGGATGAAGCCCATCGCGGCCACGGTGAACGAGAATG
TCAGGCCGTTCCGGTTCCCTAATCCGGTAAAGACAGTCGCCTCTCCCATCGTCGCGATCGATAGCGGCGCGGTGGGCTAT
GAACCCGGCCGGCCAATCCTGAAGAACCTGACGCTGCGCATCGACAATGACGACCGCATCGCTCTTCTGGGGTCGAACGG
CAACGGCAAGTCCACCTTTGCCAAGCTGATCGCCGGCAGGCTCAAGCTTGAAAGCGGAACGATGACGCTCGCGCCGGGCC
TGAAGGTCTCGATTTTTGCGCAGCACCAGCTTGATGACCTGAGGCCGGAGGAGAACGCGCACCAGCATGTGCGCCGGCTT
ATGCCGGATGCGCCCGAAGCGAAGGTGCGCGCGCGTGTGGCCCAGTTCGGCCTTTCGACGGAGAAGATGGATACGCCGGC
CAAGGAGCTTTCGGGCGGCGAAAAGGCGCGGCTGCTCATGGGGCTTGCCTCCTTCGAGGCGCCTCACCTCTTCATCCTCG
ACGAGCCGACCAACCACCTCGACATCGACAGCCGCGAGGCATTGGTGGAAGCGTTGAACGAGTTCGAGGGGGCTGTGATC
CTCATCAGCCACGACCGGCACCTTATCGAGGCCTGCGCCGACCGGCTGTGGCTCGTGAACCACGGAACCGTGCAGCCTTA
CGACGGCGACATGGAAGATTATCGCGCGCTGACGACCGGTGGAGGAAGCCGCAACCGCGAGCGGCGCGAAGCCGACAAGG
CGTCGAAGGCCGACCGCCGGAGGGAAGCTGCGAAACGTCGCGCCGCACTCGAACCGCTCGCCAAGGAAATCAAGGCCACG
GAAGGGCTGATCGAGCGTACACGCAAGCGCATCGAAGCAATCGAGGCCCAAATGGCCGATCCCGGCCTTTATGCCCGCGA
CCCGGGAAAGATCTCCACGCTCGGCAAGGAGCGCGCGGACCTGGCGCAAGCGCTCGCGCGCCAGGAGGAGAAGTGGCTGG
AGCTTTCGACGGAATATGAGGAAGGGGTGGCTGAGTAG

Upstream 100 bases:

>100_bases
CCTGAATTGCGCCAAGGGATAGCCGGGCCGAGATCAGCGCTCCGGAAAATCGCTGAACGGGCTTGCAAGCGCAGGCGGCC
TCGGCCAAAACCGCGCGGCT

Downstream 100 bases:

>100_bases
ATTGGGCAGTAAGGAATTAAGCAGTAGGGCAGTAGGTTGAGACATCTCAACCGTAACTCGGAACGAGCTCTACTTCACCT
GTTCTTGACCGCCGTGGCGC

Product: ABC transporter related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MLNINDLSLRVAGRLLIEQASLTLPAGTKAGLVGRNGTGKTTLFRAITGELSPETGSISLPKGTRIGQVAQEAPGTEEPL
IDIVLKADTERDRLMREAETAEDPHRIAEIQTRLADIDAHSAEARAAAILAGLGFGPAAQKRPASSFSGGWRMRVALAAV
LFAEPDLLLLDEPTNYLDLEGTLWLEGYLAKYPYTVLLISHDRDLLNHAVNNIVHLEGKKLTFWRGGYDQFARQYAEKAE
LQEKMRTKQEAQKKHMEAFVERFRAKASKARQAQSRLKALERMKPIAATVNENVRPFRFPNPVKTVASPIVAIDSGAVGY
EPGRPILKNLTLRIDNDDRIALLGSNGNGKSTFAKLIAGRLKLESGTMTLAPGLKVSIFAQHQLDDLRPEENAHQHVRRL
MPDAPEAKVRARVAQFGLSTEKMDTPAKELSGGEKARLLMGLASFEAPHLFILDEPTNHLDIDSREALVEALNEFEGAVI
LISHDRHLIEACADRLWLVNHGTVQPYDGDMEDYRALTTGGGSRNRERREADKASKADRRREAAKRRAALEPLAKEIKAT
EGLIERTRKRIEAIEAQMADPGLYARDPGKISTLGKERADLAQALARQEEKWLELSTEYEEGVAE

Sequences:

>Translated_625_residues
MLNINDLSLRVAGRLLIEQASLTLPAGTKAGLVGRNGTGKTTLFRAITGELSPETGSISLPKGTRIGQVAQEAPGTEEPL
IDIVLKADTERDRLMREAETAEDPHRIAEIQTRLADIDAHSAEARAAAILAGLGFGPAAQKRPASSFSGGWRMRVALAAV
LFAEPDLLLLDEPTNYLDLEGTLWLEGYLAKYPYTVLLISHDRDLLNHAVNNIVHLEGKKLTFWRGGYDQFARQYAEKAE
LQEKMRTKQEAQKKHMEAFVERFRAKASKARQAQSRLKALERMKPIAATVNENVRPFRFPNPVKTVASPIVAIDSGAVGY
EPGRPILKNLTLRIDNDDRIALLGSNGNGKSTFAKLIAGRLKLESGTMTLAPGLKVSIFAQHQLDDLRPEENAHQHVRRL
MPDAPEAKVRARVAQFGLSTEKMDTPAKELSGGEKARLLMGLASFEAPHLFILDEPTNHLDIDSREALVEALNEFEGAVI
LISHDRHLIEACADRLWLVNHGTVQPYDGDMEDYRALTTGGGSRNRERREADKASKADRRREAAKRRAALEPLAKEIKAT
EGLIERTRKRIEAIEAQMADPGLYARDPGKISTLGKERADLAQALARQEEKWLELSTEYEEGVAE
>Mature_625_residues
MLNINDLSLRVAGRLLIEQASLTLPAGTKAGLVGRNGTGKTTLFRAITGELSPETGSISLPKGTRIGQVAQEAPGTEEPL
IDIVLKADTERDRLMREAETAEDPHRIAEIQTRLADIDAHSAEARAAAILAGLGFGPAAQKRPASSFSGGWRMRVALAAV
LFAEPDLLLLDEPTNYLDLEGTLWLEGYLAKYPYTVLLISHDRDLLNHAVNNIVHLEGKKLTFWRGGYDQFARQYAEKAE
LQEKMRTKQEAQKKHMEAFVERFRAKASKARQAQSRLKALERMKPIAATVNENVRPFRFPNPVKTVASPIVAIDSGAVGY
EPGRPILKNLTLRIDNDDRIALLGSNGNGKSTFAKLIAGRLKLESGTMTLAPGLKVSIFAQHQLDDLRPEENAHQHVRRL
MPDAPEAKVRARVAQFGLSTEKMDTPAKELSGGEKARLLMGLASFEAPHLFILDEPTNHLDIDSREALVEALNEFEGAVI
LISHDRHLIEACADRLWLVNHGTVQPYDGDMEDYRALTTGGGSRNRERREADKASKADRRREAAKRRAALEPLAKEIKAT
EGLIERTRKRIEAIEAQMADPGLYARDPGKISTLGKERADLAQALARQEEKWLELSTEYEEGVAE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=528, Percent_Identity=38.4469696969697, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI27881506, Length=528, Percent_Identity=38.0681818181818, Blast_Score=344, Evalue=1e-94,
Organism=Homo sapiens, GI10947137, Length=528, Percent_Identity=38.0681818181818, Blast_Score=344, Evalue=2e-94,
Organism=Homo sapiens, GI69354671, Length=539, Percent_Identity=36.734693877551, Blast_Score=309, Evalue=5e-84,
Organism=Homo sapiens, GI10947135, Length=539, Percent_Identity=36.734693877551, Blast_Score=309, Evalue=5e-84,
Organism=Homo sapiens, GI31657092, Length=216, Percent_Identity=26.8518518518519, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1789751, Length=636, Percent_Identity=40.251572327044, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1787041, Length=525, Percent_Identity=33.7142857142857, Blast_Score=313, Evalue=2e-86,
Organism=Escherichia coli, GI1787182, Length=614, Percent_Identity=28.3387622149837, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI2367384, Length=523, Percent_Identity=28.8718929254302, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788165, Length=198, Percent_Identity=26.2626262626263, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788506, Length=223, Percent_Identity=27.8026905829596, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081791, Length=212, Percent_Identity=30.6603773584906, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789864, Length=221, Percent_Identity=28.5067873303167, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786319, Length=209, Percent_Identity=30.1435406698565, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787758, Length=201, Percent_Identity=27.363184079602, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788644, Length=235, Percent_Identity=28.936170212766, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789891, Length=214, Percent_Identity=24.2990654205607, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=35.8490566037736, Blast_Score=345, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17555318, Length=526, Percent_Identity=35.9315589353612, Blast_Score=340, Evalue=9e-94,
Organism=Caenorhabditis elegans, GI17559834, Length=546, Percent_Identity=35.5311355311355, Blast_Score=318, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17555800, Length=496, Percent_Identity=23.1854838709677, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115533608, Length=220, Percent_Identity=30.9090909090909, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=545, Percent_Identity=34.6788990825688, Blast_Score=352, Evalue=9e-98,
Organism=Saccharomyces cerevisiae, GI6320874, Length=527, Percent_Identity=33.5863377609108, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6325030, Length=408, Percent_Identity=28.921568627451, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324314, Length=438, Percent_Identity=25.5707762557078, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323278, Length=436, Percent_Identity=25.4587155963303, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=38.3301707779886, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24642252, Length=550, Percent_Identity=36.5454545454545, Blast_Score=349, Evalue=3e-96,
Organism=Drosophila melanogaster, GI18859989, Length=550, Percent_Identity=36.5454545454545, Blast_Score=349, Evalue=3e-96,
Organism=Drosophila melanogaster, GI24641342, Length=534, Percent_Identity=36.3295880149813, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI28574150, Length=214, Percent_Identity=29.9065420560748, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007328, Length=214, Percent_Identity=29.9065420560748, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007184, Length=190, Percent_Identity=29.4736842105263, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=190, Percent_Identity=29.4736842105263, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69067; Mature: 69067

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNINDLSLRVAGRLLIEQASLTLPAGTKAGLVGRNGTGKTTLFRAITGELSPETGSISL
CCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEC
PKGTRIGQVAQEAPGTEEPLIDIVLKADTERDRLMREAETAEDPHRIAEIQTRLADIDAH
CCCCCHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SAEARAAAILAGLGFGPAAQKRPASSFSGGWRMRVALAAVLFAEPDLLLLDEPTNYLDLE
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLEGYLAKYPYTVLLISHDRDLLNHAVNNIVHLEGKKLTFWRGGYDQFARQYAEKAE
CEEEEEHHHHCCCEEEEEEECCHHHHHHHHHHEEEECCCEEEEEECCHHHHHHHHHHHHH
LQEKMRTKQEAQKKHMEAFVERFRAKASKARQAQSRLKALERMKPIAATVNENVRPFRFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NPVKTVASPIVAIDSGAVGYEPGRPILKNLTLRIDNDDRIALLGSNGNGKSTFAKLIAGR
CHHHHHHCCEEEECCCCCCCCCCCCHHCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHH
LKLESGTMTLAPGLKVSIFAQHQLDDLRPEENAHQHVRRLMPDAPEAKVRARVAQFGLST
HEECCCCEEECCCCEEEEEEEHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCH
EKMDTPAKELSGGEKARLLMGLASFEAPHLFILDEPTNHLDIDSREALVEALNEFEGAVI
HHCCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
LISHDRHLIEACADRLWLVNHGTVQPYDGDMEDYRALTTGGGSRNRERREADKASKADRR
EEECCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
REAAKRRAALEPLAKEIKATEGLIERTRKRIEAIEAQMADPGLYARDPGKISTLGKERAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
LAQALARQEEKWLELSTEYEEGVAE
HHHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MLNINDLSLRVAGRLLIEQASLTLPAGTKAGLVGRNGTGKTTLFRAITGELSPETGSISL
CCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEC
PKGTRIGQVAQEAPGTEEPLIDIVLKADTERDRLMREAETAEDPHRIAEIQTRLADIDAH
CCCCCHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
SAEARAAAILAGLGFGPAAQKRPASSFSGGWRMRVALAAVLFAEPDLLLLDEPTNYLDLE
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLEGYLAKYPYTVLLISHDRDLLNHAVNNIVHLEGKKLTFWRGGYDQFARQYAEKAE
CEEEEEHHHHCCCEEEEEEECCHHHHHHHHHHEEEECCCEEEEEECCHHHHHHHHHHHHH
LQEKMRTKQEAQKKHMEAFVERFRAKASKARQAQSRLKALERMKPIAATVNENVRPFRFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
NPVKTVASPIVAIDSGAVGYEPGRPILKNLTLRIDNDDRIALLGSNGNGKSTFAKLIAGR
CHHHHHHCCEEEECCCCCCCCCCCCHHCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHH
LKLESGTMTLAPGLKVSIFAQHQLDDLRPEENAHQHVRRLMPDAPEAKVRARVAQFGLST
HEECCCCEEECCCCEEEEEEEHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCH
EKMDTPAKELSGGEKARLLMGLASFEAPHLFILDEPTNHLDIDSREALVEALNEFEGAVI
HHCCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEE
LISHDRHLIEACADRLWLVNHGTVQPYDGDMEDYRALTTGGGSRNRERREADKASKADRR
EEECCHHHHHHHHHHEEEEECCCCCCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHHHH
REAAKRRAALEPLAKEIKATEGLIERTRKRIEAIEAQMADPGLYARDPGKISTLGKERAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHH
LAQALARQEEKWLELSTEYEEGVAE
HHHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]