Click here to switch to the map view.

The map label for this gene is hflC [H]

Identifier: 110634099

GI number: 110634099

Start: 1867741

End: 1868727

Strand: Reverse

Name: hflC [H]

Synonym: Meso_1748

Alternate gene names: 110634099

Gene position: 1868727-1867741 (Counterclockwise)

Preceding gene: 110634100

Following gene: 110634098

Centisome position: 42.35

GC content: 63.32

Gene sequence:

>987_bases
ATGCAGAACCGTCTTCCCTTCATCGCCGTTCTTGCAGCGCTGGTGCTGTTCCTGCTCTATTCCTCCGTGTTCGTGGTGAA
CGAACGGCAGCAGGCGATCGTCCTGCGCTTCGGCGAGATCGTGCGGGTCGAGCGCCAGCCCGGCCTTTATTTCAAGCTGC
CCTTCGCCTTCGCCGGGGCTGATAATGTACAGGTGATCGAAGACCGCATCCTGCGCTTCGACCTCGACGATATCCGGGTT
CAGGTATCCGGCGGCAAGTTCTACGAGGTGGATGCTTTTGTCGCCTATTCGATCAATGATCCGATGCGTTTCCGGCAGGC
CGTTTCCGGCAGCATTCAGCTCGCTGAACAGCGTCTGCGCACCCGTCTCGATGCGGCGCTTCGGCGCGTTTATGGTCTGC
GTGGCTTCGAGGCGGCGCTCTCGGAAGAGCGTGGCTCCATGATGCGCGAGGTCGCCGATCAGCTTCGCCCGGATGCGGCG
TCGCTCGGGGTCGAGATCAGGGACGTCCGCATTCGCCGCACGGATTTGACCGCTGAGGTTTCGCAGCAGACCTATGACCG
CATGAAGGCGGAGCGCCTGGCCGAGGCTGAGCGCCTGCGCGCGCGGGGTCGTGAGGCGGCGGCGAGAATTCGCGCCCGCG
CCGACCGTGAAGTGGTGGAGATTCTTGCTGCCGCACAGCGAGAGGCGGAGATCCTGCGTGGTGAAGGTGAAGGGCAACGC
AACGCCATCTTTGCCGAGGCGTTTCAACGCGATCCCGGCTTCTTCGAGTTTTACCGCTCGATGGCGGCCTATCGCGAAGC
GCTCGATCCTTCAGGAACGACCATGCTTCTTTCGCCGGATTCCGATTTCTTCCGCTTCTTCGGTTCTCCGAGTGGAAGAA
ACGGCGCCGGAGGCGAGCAAGATGCCGGCGGACCGTTGACCGGTGCGATCCCACCGGCCCAGGGGCAGGAACCTGCCCCC
CGCTCTGCGCCAGCACCGGCGCAATAG

Upstream 100 bases:

>100_bases
CATATCTCCCGCTGCCCGAACTTAGGCGAACCGCGCCGCAGGCGTCCACCACACAAAATTCAAACCAGCCTGGCGTTCAG
GCGCAAGGGGGGAATAACTG

Downstream 100 bases:

>100_bases
GCAGAGCCGCGTTTGATGCGTCGTGCGTTTCCGGGGGGGCGGGTGCGGTGACTGACTTCATAGCCGCGCTCGGGCTCGTC
CTTGTCTTTGAAGGACTGCT

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MQNRLPFIAVLAALVLFLLYSSVFVVNERQQAIVLRFGEIVRVERQPGLYFKLPFAFAGADNVQVIEDRILRFDLDDIRV
QVSGGKFYEVDAFVAYSINDPMRFRQAVSGSIQLAEQRLRTRLDAALRRVYGLRGFEAALSEERGSMMREVADQLRPDAA
SLGVEIRDVRIRRTDLTAEVSQQTYDRMKAERLAEAERLRARGREAAARIRARADREVVEILAAAQREAEILRGEGEGQR
NAIFAEAFQRDPGFFEFYRSMAAYREALDPSGTTMLLSPDSDFFRFFGSPSGRNGAGGEQDAGGPLTGAIPPAQGQEPAP
RSAPAPAQ

Sequences:

>Translated_328_residues
MQNRLPFIAVLAALVLFLLYSSVFVVNERQQAIVLRFGEIVRVERQPGLYFKLPFAFAGADNVQVIEDRILRFDLDDIRV
QVSGGKFYEVDAFVAYSINDPMRFRQAVSGSIQLAEQRLRTRLDAALRRVYGLRGFEAALSEERGSMMREVADQLRPDAA
SLGVEIRDVRIRRTDLTAEVSQQTYDRMKAERLAEAERLRARGREAAARIRARADREVVEILAAAQREAEILRGEGEGQR
NAIFAEAFQRDPGFFEFYRSMAAYREALDPSGTTMLLSPDSDFFRFFGSPSGRNGAGGEQDAGGPLTGAIPPAQGQEPAP
RSAPAPAQ
>Mature_328_residues
MQNRLPFIAVLAALVLFLLYSSVFVVNERQQAIVLRFGEIVRVERQPGLYFKLPFAFAGADNVQVIEDRILRFDLDDIRV
QVSGGKFYEVDAFVAYSINDPMRFRQAVSGSIQLAEQRLRTRLDAALRRVYGLRGFEAALSEERGSMMREVADQLRPDAA
SLGVEIRDVRIRRTDLTAEVSQQTYDRMKAERLAEAERLRARGREAAARIRARADREVVEILAAAQREAEILRGEGEGQR
NAIFAEAFQRDPGFFEFYRSMAAYREALDPSGTTMLLSPDSDFFRFFGSPSGRNGAGGEQDAGGPLTGAIPPAQGQEPAP
RSAPAPAQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=319, Percent_Identity=34.1692789968652, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 36554; Mature: 36554

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRLPFIAVLAALVLFLLYSSVFVVNERQQAIVLRFGEIVRVERQPGLYFKLPFAFAGA
CCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHEEHHHHEEEECCCCEEEECCEEECCC
DNVQVIEDRILRFDLDDIRVQVSGGKFYEVDAFVAYSINDPMRFRQAVSGSIQLAEQRLR
CCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
TRLDAALRRVYGLRGFEAALSEERGSMMREVADQLRPDAASLGVEIRDVRIRRTDLTAEV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEEEEECCCHHHH
SQQTYDRMKAERLAEAERLRARGREAAARIRARADREVVEILAAAQREAEILRGEGEGQR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
NAIFAEAFQRDPGFFEFYRSMAAYREALDPSGTTMLLSPDSDFFRFFGSPSGRNGAGGEQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCC
DAGGPLTGAIPPAQGQEPAPRSAPAPAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQNRLPFIAVLAALVLFLLYSSVFVVNERQQAIVLRFGEIVRVERQPGLYFKLPFAFAGA
CCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHEEHHHHEEEECCCCEEEECCEEECCC
DNVQVIEDRILRFDLDDIRVQVSGGKFYEVDAFVAYSINDPMRFRQAVSGSIQLAEQRLR
CCHHHHHHHHHHCCCCCEEEEECCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
TRLDAALRRVYGLRGFEAALSEERGSMMREVADQLRPDAASLGVEIRDVRIRRTDLTAEV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEEEEECCCHHHH
SQQTYDRMKAERLAEAERLRARGREAAARIRARADREVVEILAAAQREAEILRGEGEGQR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
NAIFAEAFQRDPGFFEFYRSMAAYREALDPSGTTMLLSPDSDFFRFFGSPSGRNGAGGEQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCC
DAGGPLTGAIPPAQGQEPAPRSAPAPAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]